Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.119
Jihye Heo
Pseudomonas aeruginosa (P. aeruginosa), Escherichia coli (E. coli), and Staphylococcus aureus (S. aureus) are typical opportunistic pathogens. Moreover, these bacteria are known to possess multidrug-resistant (MDR) properties. This study investigates the antimicrobial activity of six fermented products, which have varying efficacies against P. aeruginosa, E. coli, and S. aureus. To identify novel candidate genes, differential expression analysis was performed using an annealing control primer. In the disk diffusion method, Fig vinegar (FV) and Diospyros kaki Thunb. vinegar (DTV) showed the greatest increase in inhibition compared to other fermented products, whereas fermented Korean traditional nature herb (FKTNH) had no antibacterial effect. This study identified down-regulation of Escherichia coli O157:H7 OmpW gene for outer membrane protein W, whereas gene for synthetic construct Lao1 gene for L-amino acid oxidase were up-regulated in E. coli treated with 5% FV. Consuming fermented vinegar helps to prevent bacterial infections. In particular, FV and DTV are potentially useful alternative natural products for multidrug resistance. Furthermore, both are expected to be used as effective natural antimicrobial agents, such as disinfectants.
{"title":"Antibacterial Effect of Various Fermentation Products and Identification of Differentially Expressed Genes of E.coli","authors":"Jihye Heo","doi":"10.15324/kjcls.2022.54.2.119","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.119","url":null,"abstract":"Pseudomonas aeruginosa (P. aeruginosa), Escherichia coli (E. coli), and Staphylococcus aureus (S. aureus) are typical opportunistic pathogens. Moreover, these bacteria are known to possess multidrug-resistant (MDR) properties. This study investigates the antimicrobial activity of six fermented products, which have varying efficacies against P. aeruginosa, E. coli, and S. aureus. To identify novel candidate genes, differential expression analysis was performed using an annealing control primer. In the disk diffusion method, Fig vinegar (FV) and Diospyros kaki Thunb. vinegar (DTV) showed the greatest increase in inhibition compared to other fermented products, whereas fermented Korean traditional nature herb (FKTNH) had no antibacterial effect. This study identified down-regulation of Escherichia coli O157:H7 OmpW gene for outer membrane protein W, whereas gene for synthetic construct Lao1 gene for L-amino acid oxidase were up-regulated in E. coli treated with 5% FV. Consuming fermented vinegar helps to prevent bacterial infections. In particular, FV and DTV are potentially useful alternative natural products for multidrug resistance. Furthermore, both are expected to be used as effective natural antimicrobial agents, such as disinfectants.","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41385570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.95
Yo-Han Seo, Hee-Young Shin
{"title":"Relationship between Lipoprotein(a) and Dyslipidemia in the Elderly over 60 Years","authors":"Yo-Han Seo, Hee-Young Shin","doi":"10.15324/kjcls.2022.54.2.95","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.95","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44318717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.125
M. Chong, Kyutaeg Lee
{"title":"The Patterns of Conversion to Anti-Tuberculosis Drug Resistance in Mycobacterium tuberculosis","authors":"M. Chong, Kyutaeg Lee","doi":"10.15324/kjcls.2022.54.2.125","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.125","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44018572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.103
Bo Kyeung Jung, Seung Keun Ham, Jae Kyung Kim
In December 2019, the coronavirus disease 2019 (COVID-19) caused by the virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China and spread rapidly around the world, infecting millions of people. Cases of COVID-19 infection were observed to lead to viral pneumonia. Thirty-five patients admitted to the Gyeonggi Medical Center, South Korea, between November 2020 to January 2021, were found to have been infected with the influenza virus A and B, which cause symptoms similar to COVID-19. The records of these patients and those of COVID-19 patients who visited the hospital for medical examination were compared. The study patients included thirty patients with COVID-19 and/or influenza, five of those with influenza alone. A group of 121 patients without infection was used as control. Patients with COVID-19 and influenza had significantly higher lactate dehydrogenase levels than the patients with COVID-19 alone. The erythrocyte sedimentation rate (ESR) was higher in patients with COVID-19 alone than in other groups. Significant clinical outliers were observed in the COVID-19 and influenza infection group compared with the COVID-19 alone group. These results are expected to play an important role in the analysis of the hematological data of infected patients and the comparison of simultaneous and single infection data to determine clinical symptoms and other signs. These results may also assist in the development of vaccines and treatments for COVID-19. Copyright Ⓒ 2022 The Korean Society for Clinical Laboratory Science.
{"title":"Comparison of Blood Test Results and Symptoms of Patients with COVID-19 Monoinfection and with COVID-19 and Influenza Virus Co-Infection","authors":"Bo Kyeung Jung, Seung Keun Ham, Jae Kyung Kim","doi":"10.15324/kjcls.2022.54.2.103","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.103","url":null,"abstract":"In December 2019, the coronavirus disease 2019 (COVID-19) caused by the virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China and spread rapidly around the world, infecting millions of people. Cases of COVID-19 infection were observed to lead to viral pneumonia. Thirty-five patients admitted to the Gyeonggi Medical Center, South Korea, between November 2020 to January 2021, were found to have been infected with the influenza virus A and B, which cause symptoms similar to COVID-19. The records of these patients and those of COVID-19 patients who visited the hospital for medical examination were compared. The study patients included thirty patients with COVID-19 and/or influenza, five of those with influenza alone. A group of 121 patients without infection was used as control. Patients with COVID-19 and influenza had significantly higher lactate dehydrogenase levels than the patients with COVID-19 alone. The erythrocyte sedimentation rate (ESR) was higher in patients with COVID-19 alone than in other groups. Significant clinical outliers were observed in the COVID-19 and influenza infection group compared with the COVID-19 alone group. These results are expected to play an important role in the analysis of the hematological data of infected patients and the comparison of simultaneous and single infection data to determine clinical symptoms and other signs. These results may also assist in the development of vaccines and treatments for COVID-19. Copyright Ⓒ 2022 The Korean Society for Clinical Laboratory Science.","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44578867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.163
N. Rashid, S. Amin, Aveen M. Raouf Abdulqader
{"title":"Diagnosis and Management of Post-Partum Hemorrhage Caused by Acquired Hemophilia A: A Case Report","authors":"N. Rashid, S. Amin, Aveen M. Raouf Abdulqader","doi":"10.15324/kjcls.2022.54.2.163","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.163","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49670023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.79
C. Lee, Dongsup Lee
{"title":"Comparison of Laboratory Tests Applied for Diagnosing the SARS-CoV-2 Infection","authors":"C. Lee, Dongsup Lee","doi":"10.15324/kjcls.2022.54.2.79","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.79","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45332527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.110
Yu-Yean Hwang, O. Kang, Chang-Eun Park, Sung-No Hong, Young-Kwon Kim, H. Huh, N. Lee
{"title":"Frequency of Candida Strains Isolated from Candidiasis Patients at A Tertiary Hospital over the Last 10 Years","authors":"Yu-Yean Hwang, O. Kang, Chang-Eun Park, Sung-No Hong, Young-Kwon Kim, H. Huh, N. Lee","doi":"10.15324/kjcls.2022.54.2.110","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.110","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67384102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.149
Hyun Yoon
{"title":"The Relationship between Lipid Accumulation Product, Insulin Resistance and Obesity in Korean Adults","authors":"Hyun Yoon","doi":"10.15324/kjcls.2022.54.2.149","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.149","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42902526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-30DOI: 10.15324/kjcls.2022.54.2.157
S. Lim, Min Hwan Jang
{"title":"Technical Considerations of Effective Direct Cortical and Subcortical Stimulation","authors":"S. Lim, Min Hwan Jang","doi":"10.15324/kjcls.2022.54.2.157","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.2.157","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46245875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-31DOI: 10.15324/kjcls.2022.54.1.73
Ho-Keun Choi, Kyung-Suk Choi
{"title":"Status of Blood Products Release at a General Hospital in Gyeonggi-Do","authors":"Ho-Keun Choi, Kyung-Suk Choi","doi":"10.15324/kjcls.2022.54.1.73","DOIUrl":"https://doi.org/10.15324/kjcls.2022.54.1.73","url":null,"abstract":"","PeriodicalId":52807,"journal":{"name":"Korean Journal of Clinical Laboratory Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43526224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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