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Influence of medical and social factors on parents' attitude to specific prevention of infectious diseases in children of the Saratov region during the new coronavirus infection pandemic 新型冠状病毒感染大流行期间医疗和社会因素对萨拉托夫地区儿童家长传染病专项预防态度的影响
Pub Date : 2023-10-04 DOI: 10.22627/2072-8107-2023-22-3-39-44
E. V. Mikhailova, T. N. Malugina, D. Yu. Levin, A. N. Polyakova, A. Yu. Serdyukov
Objective: to analyze the influence of medical and social factors on the attitude of parents to the specific prevention of infectious diseases in children during the pandemic of a new coronavirus infection. Material and methods. Anonymous questioning of parents on the attitude to vaccination was conducted. A specially designed questionnaire included questions about attitudes towards vaccines included in the National Immunization Schedule, as well as those not included in it, in particular, the desire of parents to vaccinate their children against COVID-19 was assessed. In total, 153 people aged 17 to 42 took part in the survey — parents of children aged 1 to 14 years. Results. All parents under 18 years of age support vaccination in accordance with the National Vaccination Calendar; 52.1% of parents aged 18—25 years (p < 0.001), 55.6% of parents aged 26—35 years (p < 0.001 compared to parents under 18 years old), and 66.7% of parents over 35 years old (p < 0.001 compared to parents under 18 years old and parents 18—35 years old). Conclusion. The main medical and social factors associated with the refusal to carry out preventive vaccinations for their children are: the age of parents under 35, incomplete higher education and trust in information received on the Internet. The results obtained indicate the need to determine the «risk group» among parents who express doubts about the need for vaccination. It is necessary to conduct educational programs for them in order to form a positive attitude towards the specific prevention of infectious diseases.
目的:分析新型冠状病毒感染大流行期间医学和社会因素对家长对儿童传染病专项预防态度的影响。材料和方法。对家长进行了对疫苗接种态度的匿名询问。一份专门设计的调查问卷,包括对《国家免疫计划》所列疫苗和未列入《国家免疫计划》的疫苗的态度,特别是评估父母为子女接种COVID-19疫苗的意愿。共有153名年龄在17岁到42岁之间的人参与了这项调查,他们都是1岁到14岁孩子的父母。结果。所有18岁以下的父母都支持按照国家疫苗接种日历接种疫苗;52.1%的18-25岁家长(p <0.001), 55.6%的父母年龄在26-35岁之间(p <与18岁以下的父母相比,为0.001),35岁以上的父母为66.7% (p <与18岁以下父母和18 - 35岁父母相比,差异为0.001)。结论。与拒绝为子女进行预防性疫苗接种有关的主要医疗和社会因素是:父母年龄在35岁以下、高等教育不完整以及对互联网信息的信任。所获得的结果表明,有必要在对接种疫苗的必要性表示怀疑的父母中确定“风险群体”。有必要对他们进行教育,以形成对传染病具体预防的积极态度。
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引用次数: 0
Algorithm for monitoring patients after tick bite in the context of Lyme-borreliosis 莱姆病蜱叮咬后患者监测算法研究
Pub Date : 2023-10-04 DOI: 10.22627/2072-8107-2023-22-3-14-21
R. F. Sayfullin, N. N. Zvereva, A. A. Erovichenkov, A. K. Shakaryan, M. A. Sayfullin, A. A. Samkov, E. V. Kardonova, O. V. Shamsheva
Timely diagnosis of Lyme-borreliosis (LB) is the key to its successful treatment. Outpatient monitoring of patients after tick bite based on the algorithm is able to optimize the early diagnosis of LB, shorten the start of treatment and improve the disease surveillance.Purpose. Creation of an algorithm for monitoring patients after tick bite for use in outpatient settings by primary care physicians. Material and methods. A retrospective, non-randomized, single-center cohort study was conducted based on the analysis of data from 660 outpatient records of patients consulted by an infectious disease specialist in the Infectious clinical hospital No.1 in Moscow. Patients were divided by age and the presence or absence of a diagnosis of LB. Confirmation of the diagnosis was carried out according to clinical and/or laboratory criteria using methods of enzyme-linked immunoassay and immune blot. Results. The analysis of the results of enzyme immunoassay of antibodies to borrelia in patients with LB was carried out. The optimal sampling time was 7 or more weeks from the moment of tick bite and 4 or more weeks from the moment of onset of symptoms. The specificity of immunological diagnostics in patients with excluded LB was evaluated. The proportion of doubtful and false positive results in such patients was high — 28.1%. False positive results were more common in adults (37.6%) compared with children (9.8%), which is associated with more frequent false positive results of IgM determination (34.1% in adults, 4.9% in children). Based on the data of our study, an algorithm for monitoring patients after tick bite has been developed, focused on use in outpatient settings by primary care physicians.
莱姆病(Lyme-borreliosis, LB)的及时诊断是成功治疗的关键。基于该算法对蜱叮咬后患者进行门诊监测,可优化LB的早期诊断,缩短治疗起始时间,提高疾病监测水平。创建一种算法,用于监测蜱叮咬后的病人,用于门诊设置的初级保健医生。材料和方法。对莫斯科第一感染临床医院一位传染病专家咨询的660例患者门诊记录进行了一项回顾性、非随机、单中心队列研究。患者按年龄和LB诊断的存在与否进行分类。根据临床和/或实验室标准,使用酶联免疫测定和免疫印迹方法进行诊断确认。结果。对LB患者伯氏疏螺旋体抗体酶免疫测定结果进行分析。最佳采样时间为蜱叮咬后7周及以上,症状出现后4周及以上。评估排除LB的患者免疫诊断的特异性。可疑和假阳性比例较高,达28.1%。假阳性结果在成人(37.6%)比儿童(9.8%)更常见,这与IgM检测假阳性结果更频繁相关(成人34.1%,儿童4.9%)。基于我们的研究数据,我们开发了一种蜱虫叮咬后监测患者的算法,重点是初级保健医生在门诊环境中使用。
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引用次数: 0
Триггерная роль COVID-19 в развитии сахарного диабета 1-го типа и кетоацидоза у ребенка: случай из практики 在1型糖尿病和儿童中的酮酸中毒发展中,COVID-19的触发器作用:实践中的例子
Pub Date : 2023-06-27 DOI: 10.22627/2072-8107-2023-22-2-56-60
V. V. Sokolovskaya, A. A. Litvinova, N. N. Smolyankin, A. V. Krikova, R. S. Kozlov
It has been proven that the SARS-CoV-2 virus is able to initiate the development of a number of metabolic disorders, leading to diabetes mellitus (DM). Given the high frequency of cases of newly diagnosed type 1 diabetes in children, as well as possible adverse prospective consequences, the study of such clinical cases seems to us to be an extremely relevant practice for doctors of all specialties. The aim of the study was to to demonstrate of a clinical case of newly diagnosed type 1 diabetes in a child with COVID-19. The article presents a general understanding of the pathogenetically bidirectional relationship between a new coronavirus infection and diabetes mellitus, presents a clinical case of type 1 diabetes diagnosed for the first time in a child 3 years 8 months with COVID-19, and describes the further stage of treatment in the specialized endocrinology department. Conclusion. The clinical case presented by us, as well as data obtained as a result of research by domestic and foreign colleagues, confirm the existence of a pathogenetically determined relationship between COVID-19 and type 1 diabetes mellitus in children. To better understand the mechanisms underlying the devel- opment of metabolic suffering, it is necessary to create a single Global registry of patients with diabetes mellitus, first identified in connection with COVID-19.
已经证明,SARS-CoV-2病毒能够引发多种代谢紊乱,导致糖尿病(DM)。鉴于儿童中新诊断的1型糖尿病病例的高频率,以及可能的不良预期后果,对这些临床病例的研究在我们看来对所有专业的医生来说都是非常相关的实践。该研究的目的是证明一名患有COVID-19的儿童新诊断为1型糖尿病的临床病例。本文介绍了新型冠状病毒感染与糖尿病的病理双向关系,介绍了1例3岁8个月新冠肺炎患儿首次诊断为1型糖尿病的临床病例,并介绍了在专科内分泌科的进一步治疗。结论。我们提出的临床病例,以及国内外同行的研究数据,证实了COVID-19与儿童1型糖尿病之间存在病理确定的关系。为了更好地了解代谢性痛苦发生的机制,有必要建立一个单一的全球糖尿病患者登记册,首先与COVID-19有关。
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