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Prevalence, Correction Coverage, Unmet Need and Impact on the Quality of Life of Presbyopia among Market Traders in Ibadan, Nigeria. 尼日利亚伊巴丹市场商贩中老花眼的患病率、矫正覆盖率、未满足需求及其对生活质量的影响。
Q4 Pharmacology, Toxicology and Pharmaceutics Pub Date : 2020-07-01
O Adeyemi, C O Bekibele

Presbyopia is an age-related condition that results from the gradual decline in accommodation leading to inability to focus at near distances. This study sought to determine the prevalence, correction coverage, unmet need and impact on the quality of life of presbyopia among Bodija market traders in Ibadan, Nigeria. A cross sectional study was conducted on 314 participants aged 35 years and older selected by a non-probability sampling method. Their near vision was tested and corrected to the nearest diopter. Presbyopia was defined as being able to read the N8 optotype at a distance of 40 cm after correction with plus lens of at least one diopter. The prevalence of presbyopia was 46.8% (95% CI: 41.20, 52.5). The prevalence was significantly higher in those aged 50 years or more (95% CI: 2.98, 7.77), in females (95% CI: 1.45, 3.64) and in individuals with no formal education (95%CI: 3.32, 10.91). The presbyopia correction coverage was 29.9% and unmet need was = 70.1%. The major barriers reported as reasons for not obtaining near vision spectacles were lack of money and spectacles not being a priority. Presbyopes reported more difficulty with near work (p<0.001). The prevalence of presbyopia in Bodija market is relatively low compared to other reports with major risk factors being increasing age, female gender and no formal education. Presbyopia correction coverage is low with high unmet need it is important to create awareness and provide affordable and accessible near vision spectacles for those in need.

老花眼是一种与年龄有关的疾病,是由于调节力逐渐下降导致近距离无法聚焦。本研究旨在确定尼日利亚伊巴丹 Bodija 市场商贩中老花眼的患病率、矫正范围、未满足的需求以及对生活质量的影响。研究采用非概率抽样法对 314 名 35 岁及以上的参与者进行了横断面研究。对他们的近视力进行了测试,并校正到最接近的屈光度。老花眼的定义是,在使用至少一个屈光度的加倍镜片进行矫正后,能够在 40 厘米的距离上读取 N8 光型。老花眼的患病率为 46.8%(95% CI:41.20,52.5)。年龄在 50 岁或以上(95% CI:2.98, 7.77)、女性(95% CI:1.45, 3.64)和未接受过正规教育(95%CI:3.32, 10.91)的人群的患病率明显更高。老花眼矫正覆盖率为 29.9%,未满足的需求=70.1%。据报告,不配戴近视眼镜的主要障碍是没钱和不优先配戴眼镜。老花眼在近距离工作时遇到的困难更大(p
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引用次数: 0
Modifiable Risk Factors for Overweight and Obesity Among Traders In Abeokuta South Local Government Area, Ogun State 奥贡州阿倍奥库塔南地方政府区贸易商超重和肥胖的可修改风险因素
Q4 Pharmacology, Toxicology and Pharmaceutics Pub Date : 2019-05-31 DOI: 10.4314/AJBR.V22I2.%C
C. Oladoyinbo, A. M. Abiodun, O. O. Akinbule, I. Okeke, E. B. John
The market place as an occupational environment can predispose to obesity, mainly due to sedentary nature and enhanced access to food. This study was designed to determine the prevalence and risk factors of overweight and obesity among traders in Abeokuta South Local Government Area, Ogun State, Nigeria. A descriptive cross-sectional research design involving 210 (60.3%) males and 140 (39.7%) females randomly selected from three markets (Panseke, Kuto and Asero markets) was conducted using a systematic random sampling method. A validated semi-structured questionnaire was used to assess their personal and socio-economic characteristics, alcohol consumption, smoking habits and physical activity levels. Nutrient intake was assessed using a validated 24hr Dietary Recall questionnaire. Body Mass Index (BMI) was derived from height and weight measurements; Waist and hip circumference was taken to assess abdominal obesity. The nutrient intake was analyzed using the adapted Total Diet Allowance (TDA) for windows. Data was analyzed using the Statistical Package for Social Sciences (SPSS), version 20. Based on BMI, the prevalence of overweight and obesity was 24% and 3.7% respectively. About 39.4% of the respondents had abdominal obesity. The prevalence of general obesity was significantly higher among females than males (p=0.000). Over one-third (41.4%) of the respondent have low physical activity level. About 14.9% of the respondents smoke cigarrete and more than one-third (35.1%) consume alcohol. More than half (58.6%) of the males and 89.7% of the females had excess calorie intake in the past 24 hours. A significant association was observed between BMI and smoking pattern but there was no significant association between BMI, physical activity and alcohol consumption pattern. Carbohydrate, protein and fat were consumed above the recommended dietary allowance, while respondents had inadequate intake of micro-nutrients, as well as fiber. Obesity is of public health concern, therefore, sensitization focused on lifestyle modification and proper dietary choices should be considered.Keywords: Traders, alcohol consumption, physical activity, obesity, dietary habitsAfr. J. Biomed. Res. Vol. 22 (May, 2019); 127- 133
市场作为一种职业环境可能容易导致肥胖,这主要是由于久坐的天性和获得食物的机会增加。本研究旨在确定尼日利亚奥贡州Abeokuta South地方政府区贸易商超重和肥胖的患病率和风险因素。采用系统随机抽样方法,对从三个市场(Panseke、Kuto和Asero市场)随机选择的210名(60.3%)男性和140名(39.7%)女性进行了描述性横断面研究设计。使用经验证的半结构化问卷来评估他们的个人和社会经济特征、饮酒量、吸烟习惯和体育活动水平。使用经验证的24小时膳食回忆问卷评估营养摄入。体重指数(BMI)来源于身高和体重测量;测量腰围和臀围以评估腹部肥胖。采用适用于窗口的总膳食津贴(TDA)对营养摄入进行分析。使用社会科学统计软件包(SPSS)第20版对数据进行分析。根据BMI,超重和肥胖的患病率分别为24%和3.7%。约39.4%的受访者患有腹部肥胖。女性普遍肥胖的患病率明显高于男性(p=0.000)。超过三分之一(41.4%)的受访者体力活动水平较低。约14.9%的受访者吸烟,超过三分之一(35.1%)的受访者饮酒。超过一半(58.6%)的男性和89.7%的女性在过去24小时内摄入了过量的卡路里。观察到BMI与吸烟模式之间存在显著关联,但BMI、体育活动和饮酒模式之间没有显著关联。碳水化合物、蛋白质和脂肪的摄入量超过了建议的饮食摄入量,而受访者的微量营养素和纤维摄入量不足。肥胖是公众健康关注的问题,因此,应考虑对生活方式的改变和适当的饮食选择进行宣传。关键词:贸易商,饮酒,体育活动,肥胖,饮食习惯。J.Biomed。Res.Vol.22(2019年5月);127-133
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引用次数: 4
Validity and Reliability of Hausa Version of The World Health Organization Quality of Life-Short Form Among Spinal Cord Injury Survivors 世界卫生组织Hausa版脊髓损伤幸存者生活质量简表的有效性和可靠性
Q4 Pharmacology, Toxicology and Pharmaceutics Pub Date : 2018-09-30 DOI: 10.4314/AJBR.V21I3
Roland Suluku, Ahmadu Tejan Jalloh, B. Emikpe
Background: The World Health Organization’s Quality of Life Bref (WHOQoL-Bref) is a well-validated, cross-cultural tool and widely-used for measuring Quality of Life (QoL) across different populations. The aim of this study was to translate the WHOQoL-Bref into the Hausa language and investigate the validity and reliability of the Hausa version among patients with spinal cord injury. Methods: The source English version of WHOQoL-Bref was translated into Hausa language through a forward-back translation phase, which involved two rounds of back translation. Individuals with spinal cord injury (ISCI) and their sex- and age-matched apparently healthy individuals (AHI) participated in this correlational study.  Participants were selected through purposive sampling technique. The ISCI were recruited from selected physiotherapy clinics of tertiary health institution in Northern Nigeria while the AHI were recruited from the same tertiary health institution. The ISCI completed both English and Hausa versions of WHOQoL-Bref while the AHI completed only the Hausa version. The ISCI also completed the Hausa version of WHOQoL-Bref two weeks after the initial administration. Data were analysed using Pearson correlation and dependent t-test. Level of significance was set at 0.05 ᾳ level. Results:The ISCHI  (38 males; 11 females) and AHI  (38 males; 11 females) were aged 32.86±7.15years and 33.68±7.15years respectively. The mean duration of SCI is 20.43±9.03months. Domain scores on the Hausa version of the WHOQoL-Bref correlated significantly with English version (r=0.514-0.638, p=<0.0001). There were differences between scores obtained by participants with SCI and those without SCI on the Hausa version. Domain scores on the Hausa version of WHOQoL-Bref obtained on the first and second administrations correlated significantly (r=0.413-0.766, p=<0.0001). Conclusion:The Hausa translated version  of WHOQoL-Bref  is a valid and reliable instrument, for assessing QoL of spinal cord injury survovors. It is recommended for use in Hausa-speaking populations.
背景:世界卫生组织的生活质量Bref(WHOQoL-Bref)是一种经过充分验证的跨文化工具,广泛用于衡量不同人群的生活质量。本研究的目的是将WHOQoL Bref翻译成豪萨语,并调查豪萨语版本在脊髓损伤患者中的有效性和可靠性。方法:将WHOQoL Bref的源英文版本通过前后翻译阶段翻译成豪萨语,前后翻译阶段包括两轮。患有脊髓损伤(ISCI)的个体及其性别和年龄匹配的明显健康个体(AHI)参与了这项相关研究。参与者是通过有目的的抽样技术选出的。ISCI是从尼日利亚北部三级卫生机构的选定理疗诊所招募的,而AHI是从同一个三级卫生组织招募的。ISCI完成了WHOQoL Bref的英语和豪萨语版本,而AHI只完成了豪萨语版。ISCI还在初次给药两周后完成了WHOQoL Bref的豪萨版本。使用Pearson相关和相关t检验对数据进行分析。显著性水平设定为0.05ᾳ 数量结果:ISCHI(38名男性,11名女性)和AHI(38名女性,11名男性)的年龄分别为32.86±7.15岁和33.68±7.15年。SCI的平均持续时间为20.43±9.03个月。Hausa版WHOQoL Bref的领域得分与英文版显著相关(r=0.514-0.638,p=0.0001)。有SCI和无SCI的参与者在Hausa版本上的得分存在差异。Hausa版WHOQoL-Bref在第一次和第二次给药时的领域得分显著相关(r=0.413-0.766,p=0.0001)。结论:Hausa翻译版WHOQoL-Bref是评估脊髓损伤幸存者生活质量的有效和可靠的工具。建议在豪萨语人群中使用。
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引用次数: 6
Effects of Diets Containing Unripe Plantain Diet on Brain Serotonin in Mice 未成熟车前草日粮对小鼠脑血清素的影响
Q4 Pharmacology, Toxicology and Pharmaceutics Pub Date : 2017-09-30 DOI: 10.4314/AJBR.V20I3
Idayat Titilayo Gbadamosi, Lekan Abdullahi Raji, A. Oyagbemi, T. O. Omobowale
Musa paradisiaca (Plantain) fruit has been shown to be useful for nutritional, medicinal and industrial purposes. It contains serotonin (5-HT) and its immediate precursor, 5-Hydroxytryptophan (5-HTP). Serotonin plays a fundamental role in integration of behaviour and many physiological functions including regulation of mood, anxiety, arousal, aggression, impulse control, and thinking abilities. In this study, the effect of plantain-containing mouse diet on brain serotonin mice was investigated in mice. Thirty adult Swiss mice were divided into three groups of ten each and fed normal rodent chow containing 0%, 50% and 100% unripe plantain. After thirty days, the brain levels of 5-HT and 5-HTP were measured using High Performance Liquid Chromatography (HPLC) technique. Results show that 5-HT level was significantly increased in the plantain-diet fed mice. Conversely, 5-HTP level was reduced in the 100% plantain fed mice when compared with the control. Keywords : Musa paradisiaca , Unripe plantain, serotonin, 5-Hydroxytryptophan
芭蕉果实已被证明可用于营养、药用和工业用途。它含有5-羟色胺(5-HT)及其直接前体5-羟色氨酸(5-HTP)。血清素在行为和许多生理功能的整合中发挥着重要作用,包括调节情绪、焦虑、唤醒、攻击性、冲动控制和思维能力。在本研究中,研究了含车前草的小鼠饮食对小鼠大脑血清素的影响。将30只成年瑞士小鼠分为三组,每组10只,喂食含有0%、50%和100%未成熟车前草的正常啮齿动物食物。30天后,用高效液相色谱(HPLC)技术测定脑内5-HT和5-HTP的水平。结果表明,在车前草日粮喂养的小鼠中,5-HT水平显著升高。相反,与对照组相比,100%车前草喂养的小鼠的5-HTP水平降低。关键词:芭蕉、未成熟芭蕉、5-羟色胺、5-羟色氨酸
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引用次数: 8
Effects of endocrine disrupting heavy metals on pituitary and gonadal hormones in normal weight automechanics in Ibadan, Nigeria 内分泌干扰重金属对尼日利亚伊巴丹正常体重汽车修理工垂体和性腺激素的影响
Q4 Pharmacology, Toxicology and Pharmaceutics Pub Date : 2017-05-01 DOI: 10.4314/AJBR.V20I1
E. Olanrewaju, B. Anyaehie, C. O. Ezeh, K. Onyekwelu, R. Ezeh
Association of hypogonadism and visceral obesity (VO) was recently demonstrated in male auto-mechanics occupationally exposed to endocrine disruptors (ED)-lead, cadmium, mercury and arsenic, known to alter the hypothalamic-pituitary-testicular axis. The effects of exposure to these EDs on pituitary and gonadal hormones in normal weight auto-mechanics in Ibadan were investigated. Ninety-nine normal weight male adults without any metabolic syndrome component-elevated VO, blood pressure, tryglycerides, fasting plasma glucose (FPG) and reduced high density lipoprotein cholesterol (HDLC), enrolled into this prospective cross sectional study. They were 50 auto-mechanics, age and anthropometry matched with 49 eugonadic males (occupationally unexposed to EDs) in Ibadan (control). Demography, lifestyle, sexual and reproductive history, anthropometery and blood pressure were obtained by standard methods. Fasting blood (15 mL) obtained was used for biochemical analyses-hormones (follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, oestradiol and testosterone) by ELISA; EDs-Lead, cadmium, mercury and arsenic by AAS; FPG, HDLC, triglycerides and oxidative stress (OS) biomarker-total antioxidant capacity (TAC) by spectrophotometry. Data obtained were statistically significant at P <0.05. Only 45 (90%) auto-mechanics were eugonadic. EDs except arsenic were significantly higher while libido and TAC level were significantly lower in the auto-mechanics compared with control ( P <0.05). In automechanics only, lead had an inverse relationship with testosterone ( P = 0.001) but direct relationship with FSH ( P = 0.013). LH had a direct relationship with mercury ( P = 0.031) but indirect relationship with TAC ( P <0.001). Auto mechanics may be occupational exposed to lead, cadmium and mercury with the induction of oxidative stress and testicular dysfunction. Keywords: Heavy Metals, Hypogonadism, Metabolic Syndrome, Total Antioxidant Capacity, Testosterone
性腺功能减退和内脏性肥胖(VO)的关联最近在男性汽车修理工职业暴露于内分泌干扰物(ED)-铅,镉,汞和砷,已知改变下丘脑-垂体-睾丸轴。研究了暴露于这些ed对伊巴丹市正常体重的机械工人垂体和性腺激素的影响。这项前瞻性横断面研究纳入了99名正常体重的男性成年人,他们没有任何代谢综合征成分——VO升高、血压升高、甘油三酯升高、空腹血糖(FPG)和高密度脂蛋白胆固醇(HDLC)降低。他们是50名汽车修理工,年龄和人体测量与49名伊巴丹(对照组)的正常性腺男性(职业未暴露于ed)相匹配。人口统计、生活方式、性和生殖史、人体测量和血压均采用标准方法。取空腹血15ml进行生化分析——激素(促卵泡激素(FSH)、促黄体生成素(LH)、催乳素、雌二醇、睾酮)ELISA法测定;原子吸收光谱法测定铅、镉、汞和砷;分光光度法测定FPG、HDLC、甘油三酯和氧化应激(OS)生物标志物-总抗氧化能力(TAC)。所得数据均有统计学意义,P <0.05。只有45例(90%)的自动机械师是良性的。除砷外的EDs显著高于对照组,性欲和TAC显著低于对照组(P <0.05)。仅在汽车力学中,铅与睾酮呈负相关(P = 0.001),但与FSH呈正相关(P = 0.013)。LH与汞有直接关系(P = 0.031),与TAC有间接关系(P <0.001)。汽车修理工可能是职业性接触铅、镉和汞,诱发氧化应激和睾丸功能障碍。关键词:重金属,性腺功能减退,代谢综合征,总抗氧化能力,睾酮
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引用次数: 11
期刊
African Journal Biomedical Research
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