Sinapse最新文献

{"title":"Custo e Carga da Atrofia Muscular Espinhal em Portugal","authors":"João Costa","doi":"10.46531/sinapse/ao/210058/2021","DOIUrl":"https://doi.org/10.46531/sinapse/ao/210058/2021","url":null,"abstract":"","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48074384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractory Post-Dural Puncture Headache: The Utility of Computed Tomography Myelography","authors":"José Lourenço Rosa","doi":"10.46531/sinapse/cc/210049/2021","DOIUrl":"https://doi.org/10.46531/sinapse/cc/210049/2021","url":null,"abstract":"","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41994455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Presentation of Spontaneous Carotid Artery Dissection","authors":"Abreu Ângela","doi":"10.46531/sinapse/in/210018/2021","DOIUrl":"https://doi.org/10.46531/sinapse/in/210018/2021","url":null,"abstract":"","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43125229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balo’s Concentric Sclerosis Mimicking High-Grade Tumor","authors":"Catarina Pinto","doi":"10.46531/sinapse/in/210066/2021","DOIUrl":"https://doi.org/10.46531/sinapse/in/210066/2021","url":null,"abstract":"","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45866329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflexões","authors":"Catarina Resende de Oliveira","doi":"10.11606/issn.2318-9800.v0i14p119-121","DOIUrl":"https://doi.org/10.11606/issn.2318-9800.v0i14p119-121","url":null,"abstract":"Com embasamento nos estudos feitos pelos pesquisadores Pierre Dardot e Chistian Laval, o presente artigo tece reflexões sobre o neoliberalismo configurado como uma racionalidade","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45449149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pandemia COVID-19: Mitigação de uma Injustiça","authors":"J. Barros, Porto Portugal Centro Hospitalar Universitário do Porto","doi":"10.46531/sinapse/ed/covid19/barrosj/2020","DOIUrl":"https://doi.org/10.46531/sinapse/ed/covid19/barrosj/2020","url":null,"abstract":"","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44429063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Miller-Fisher Syndrome: clinical features and diagnostic challenges","authors":"AI Martins, Vasconcelos, Palavra","doi":"10.46531/SINAPSE/2020/CC/190008/2020","DOIUrl":"https://doi.org/10.46531/SINAPSE/2020/CC/190008/2020","url":null,"abstract":"Miller-Fisher syndrome is an acute demyelinating polyneuropathy and classically presents with ophthalmoplegia, hyporeflexia, and ataxia. Although being one of the rare variants of Guillain-Barré syndrome, there are several clinical, laboratory and imaging peculiarities of Miller-Fisher syndrome inherent to patient’s age group. We present a three-year old patient, which presented with a three days-history of gait imbalance and ocular movements impairment. Neurological examination revealed complete ophthalmoplegia, appendicular and axial ataxia and hyporeflexia. Cerebrospinal fluid study revealed albuminocytologic dissociation while nerve conduction tests, brain magnetic resonance imaging and anti-ganglioside antibodies screening were unrevealing. The patient was diagnosed with Miller-Fisher syndrome and started intravenous human immunoglobulin (2 g/kg), for 5 days. Three months after the diagnosis, the patient was fully recovered and the neurological examination was unremarkable. It is crucial to recognize pediatric Miller-Fisher syndrome particularities, surpass the difficulties in performing an accurate neurological exam in young patients and recognize the multiple entities to consider n the differential diagnosis of pediatric Miller-Fisher syndrome, in order to perform a correct diagnosis and establish an appropriate therapeutic strategy. Informações/Informations: Caso Clínico, publicado em Sinapse, Volume 20, Número 1, janeiro-março 2020. Versão eletrónica em www.sinapse.pt Case Report, published in Sinapse, Volume 20, Number 1, january-march 2020. Electronic version in www.sinapse.pt © Autor (es) (ou seu (s) empregador (es)) 2020. Reutilização permitida de acordo com CC BY-NC. Nenhuma reutilização comercial. © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. Palavras-chave: Criança; Gangliosídeos; Imunoglobulinas Intravenosas; Síndrome de Miller-Fisher/ diagnóstico; Síndrome de Miller-Fisher/ tratamento.","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47261570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cefaleia e Doença Celíaca: O Que Há em Comum?","authors":"Ana Carvalho","doi":"10.46531/SINAPSE/CC/190027/2020","DOIUrl":"https://doi.org/10.46531/SINAPSE/CC/190027/2020","url":null,"abstract":"Celiac disease is a condition with a large spectrum of manifestations that goes far beyond the classic presentation, with poor weight progression. Extra-intestinal manifestations play an important role in the diagnostic approach and should therefore be recognized. Headache may be considered an extra-intestinal manifestation of the disease or may arise throughout its course. There is an increased prevalence of headache in celiac disease patients and vice-versa. We present the case of a 5-year-old boy with a diagnosis of celiac disease (established in the context of investigation for poor weight progression), who had complaints of episodic headache and paroxysmal vertigo. The semiology of the condition, the diagnostic categorization of headache and its accompanying symptoms are discussed, considering its primary or secondary features, in this case to the underlying autoimmune disease. Sinapse | Volume 20 | N.o 1 | January-March 2020 72 Introdução A cefaleia é uma queixa comum em crianças e adolescentes,1 assumindo uma prevalência elevada na população geral e sendo caracterizada por variáveis clínicas muito diversas, de onde resultam vários tipos de diagnósticos (de cefaleias primárias a secundárias, o espectro clínico é muito amplo). Pode apresentar-se como contínua, intermitente ou ocasional e associar-se, por vezes, a náuseas, vómitos ou sintomas neurológicos transitórios. Em crianças, a cefaleia é geralmente benigna, transitória e com um prognóstico favorável, mas o aparecimento dos sintomas supracitados pode fazer com que a expressão clínica de uma entidade dita benigna se transforme num evento com impacto muito negativo no dia-a-dia das crianças e das famílias, desde logo contribuindo para o absentismo escolar e, necessariamente, complicando o relacionamento com os pares.1 A coexistência de diferentes tipos de cefaleia pode dificultar um diagnóstico preciso.2 Ainda assim, é importante concretizá-lo, pois algumas entidades beneficiam de tratamento específico, contribuindo para uma importante redução da frequência das queixas e, naturalmente, para um incremento da qualidade de vida.3 A doença celíaca (DC) é uma enteropatia dependente de glúten,2 sendo considerada uma doença autoimune, desencadeada pela ingestão desse tipo de proteína.4 Tem uma prevalência estimada de aproximadamente 0,7%-2% na população em geral e 0,4%-1,3% em crianças.5,6 Ocorre principalmente no intestino delgado proximal, em indivíduos geneticamente suscetíveis.7 As manifestações clínicas da doença variam e podem incluir desde sintomatologia gastrointestinal típica a queixas intestinais mínimas, incomuns ou ausentes, havendo também possibilidade de ocorrência de manifestações extraintestinais5 Sintomas neurológicos podem constituir-se como manifestação extraintestinal da doença7 (os mais característicos são a ataxia cerebelosa e as queixas sugestivas de uma neuropatia periférica),8 podendo desenvolver-se durante a evolução da mesma ou ser uma apresentação inicial.6 As queixas","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45266000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teleneurology: current situation, opportunities and challenges in Portugal","authors":"Laura Teixeira","doi":"10.46531/sinapse/2020/ar/200013/2020","DOIUrl":"https://doi.org/10.46531/sinapse/2020/ar/200013/2020","url":null,"abstract":"The increasing prevalence and high morbidity and mortality of neurological diseases in Portugal poses new challenges for healthcare Given the unequal regional distribution of neurologists in the country, the implementation of teleneurology emerges as an alternative to improve accessibility to specialised care and to address these long-term challenges In this article, we review the literature regarding the safety, benefits and risks of using teleneurology in different neurological disorders The results show that teleneurology has proven to be a useful tool for patient orientation at primary and hospital level Its potential is particularly relevant in cerebrovascular disorders Teleneurology consultations have been considered satisfactory by patients and healthcare professionals, saving patients and institutions’ time and costs Challenges to its widespread implementation include equipment costs, patient data security and digital (i)literacy","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48432713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mielinólise Pôntica e Extrapôntica Secundária a Hiperglicemia","authors":"Manuel Machado","doi":"10.46531/sinapse/in/190038/2020","DOIUrl":"https://doi.org/10.46531/sinapse/in/190038/2020","url":null,"abstract":"","PeriodicalId":53695,"journal":{"name":"Sinapse","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48953729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}