Pub Date : 2023-01-01DOI: 10.4103/injr.injr_247_21
S. Sandip, S. Chandarashekhara
Chronic recurrent multifocal osteomyelitis (CRMO) is a noninfective auto-inflammatory bone disease; characterized by multifocal involvement of bone. This condition is primarily seen in children and adolescents though sometimes can be found in adults. It is primarily diagnosis of exclusion which is made in conjunction with radiological finding with clinical details with/or histopathology and at present no single test or modality is available to make the diagnosis. Magnetic resonance (MR) imaging can give clue to the diagnosis by demonstration of the involvement of bone in a specific distribution pattern. We report a case of an 11-year-old girl with MR features of CRMO.
{"title":"Chronic recurrent multifocal osteomyelitis on magnetic resonance imaging","authors":"S. Sandip, S. Chandarashekhara","doi":"10.4103/injr.injr_247_21","DOIUrl":"https://doi.org/10.4103/injr.injr_247_21","url":null,"abstract":"Chronic recurrent multifocal osteomyelitis (CRMO) is a noninfective auto-inflammatory bone disease; characterized by multifocal involvement of bone. This condition is primarily seen in children and adolescents though sometimes can be found in adults. It is primarily diagnosis of exclusion which is made in conjunction with radiological finding with clinical details with/or histopathology and at present no single test or modality is available to make the diagnosis. Magnetic resonance (MR) imaging can give clue to the diagnosis by demonstration of the involvement of bone in a specific distribution pattern. We report a case of an 11-year-old girl with MR features of CRMO.","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"18 1","pages":"78 - 80"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47491731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/injr.injr_178_22
Vattikuti Anusha, VarshaRajat Bhatt, ShwetaSuryakant Khopde, A. Zanwar
{"title":"An unusual case of ankle joint swelling: A young girl with cerebrotendinous xanthomatosis","authors":"Vattikuti Anusha, VarshaRajat Bhatt, ShwetaSuryakant Khopde, A. Zanwar","doi":"10.4103/injr.injr_178_22","DOIUrl":"https://doi.org/10.4103/injr.injr_178_22","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70775716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rashi Maheshwari, R. Sankaralingam, S. Chinnadurai, B. Chilukuri, Joseph T Antony
{"title":"Spectrum of macrophage activation syndrome in rheumatic diseases: A kaleidoscope","authors":"Rashi Maheshwari, R. Sankaralingam, S. Chinnadurai, B. Chilukuri, Joseph T Antony","doi":"10.4103/injr.injr_90_22","DOIUrl":"https://doi.org/10.4103/injr.injr_90_22","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"232 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70778544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/injr.injr_102_21
K. Chandwar
{"title":"Time to bring the background therapy to forefront","authors":"K. Chandwar","doi":"10.4103/injr.injr_102_21","DOIUrl":"https://doi.org/10.4103/injr.injr_102_21","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"18 1","pages":"113 - 113"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49583554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving drug trial success rates in systemic lupus erythematosus: Endotyping-based patient stratification could be the way forward","authors":"AnandN Malaviya, Neeraj Jain","doi":"10.4103/injr.injr_63_23","DOIUrl":"https://doi.org/10.4103/injr.injr_63_23","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135609302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Sureja, N. Sureja, T. Paul, S. Sistla, K. Tagore
{"title":"Immunoglobulin G4-related isolated cervical lymphadenopathy","authors":"V. Sureja, N. Sureja, T. Paul, S. Sistla, K. Tagore","doi":"10.4103/injr.injr_61_21","DOIUrl":"https://doi.org/10.4103/injr.injr_61_21","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"18 1","pages":"114 - 116"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44344355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swapnali Sabhapandit, Madhuri H Radhakrishna, Shireesha Anumula, A. Shaik, S. Perumalla, Sahithi Venapally
Objectives: The objective of this study was to evaluate the efficacy and safety of 0.1% cyclosporine A (CsA) eyedrop in patients having primary Sjogren's syndrome (SS) in India. Methods: A prospective consecutive case series of total 20 patients with moderate-to-severe dry eyes were treated with 0.1% CsA eyedrop twice daily along with lubricating eyedrop for 3 months. Efficacy measures included ocular staining score (OSS), van Bijsterveld score (VBS), and Schirmer's score of each eye based on the 2016 ACR-EULAR classification. Subjective improvement was also recorded at the final visit. Any adverse effects were noted. Results: Treatment with 0.1% CsA eyedrop showed a statistically significant improvement at 3 months for both OSS and VBS in each eye of study patients. A similar improvement in Schirmer's score was noted in each eye of the subjects. Subjective improvement of ocular sicca symptoms was also demonstrated. There was excellent compliance to therapy. The 0.1% CsA formulation did not show any topical or systemic side effects in any patient. Conclusion: The 0.1% ophthalmic preparation of CsA is safe and effective in the management of moderate-to-severe dry eyes in patients with primary SS in this pilot study in Indian patients.
{"title":"Efficacy of cyclosporine eyedrop 0.1% in the treatment of dry eye in primary sjogren's syndrome: A prospective Indian study","authors":"Swapnali Sabhapandit, Madhuri H Radhakrishna, Shireesha Anumula, A. Shaik, S. Perumalla, Sahithi Venapally","doi":"10.4103/injr.injr_49_22","DOIUrl":"https://doi.org/10.4103/injr.injr_49_22","url":null,"abstract":"Objectives: The objective of this study was to evaluate the efficacy and safety of 0.1% cyclosporine A (CsA) eyedrop in patients having primary Sjogren's syndrome (SS) in India. Methods: A prospective consecutive case series of total 20 patients with moderate-to-severe dry eyes were treated with 0.1% CsA eyedrop twice daily along with lubricating eyedrop for 3 months. Efficacy measures included ocular staining score (OSS), van Bijsterveld score (VBS), and Schirmer's score of each eye based on the 2016 ACR-EULAR classification. Subjective improvement was also recorded at the final visit. Any adverse effects were noted. Results: Treatment with 0.1% CsA eyedrop showed a statistically significant improvement at 3 months for both OSS and VBS in each eye of study patients. A similar improvement in Schirmer's score was noted in each eye of the subjects. Subjective improvement of ocular sicca symptoms was also demonstrated. There was excellent compliance to therapy. The 0.1% CsA formulation did not show any topical or systemic side effects in any patient. Conclusion: The 0.1% ophthalmic preparation of CsA is safe and effective in the management of moderate-to-severe dry eyes in patients with primary SS in this pilot study in Indian patients.","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"18 1","pages":"74 - 77"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49561301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/injr.injr_185_22
A. Nair, Sharath Kumar, V. Chaturvedi, P. Rath, V. Vasdev
{"title":"Is it time to introduce structured musculoskeletal ultrasound training in the rheumatology curriculum in India?","authors":"A. Nair, Sharath Kumar, V. Chaturvedi, P. Rath, V. Vasdev","doi":"10.4103/injr.injr_185_22","DOIUrl":"https://doi.org/10.4103/injr.injr_185_22","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"298 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70775770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The methotrexate story: How did a cancer chemotherapeutic agent become a disease-modifying antirheumatic drug","authors":"A. Malaviya, Astha Sareen","doi":"10.4103/injr.injr_13_23","DOIUrl":"https://doi.org/10.4103/injr.injr_13_23","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70774394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.4103/injr.injr_189_22
Shaariq Naqati, Mushtaq Ahmad, FarooqAhmad Guroo, F. Sofi, T. Shah
{"title":"Clinical and serological profile of Sjögren's syndrome patients in a tertiary care center in Kashmir, North India","authors":"Shaariq Naqati, Mushtaq Ahmad, FarooqAhmad Guroo, F. Sofi, T. Shah","doi":"10.4103/injr.injr_189_22","DOIUrl":"https://doi.org/10.4103/injr.injr_189_22","url":null,"abstract":"","PeriodicalId":54167,"journal":{"name":"Indian Journal of Rheumatology","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70775563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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