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Analysis of the Hospital Medical Surge Preparedness Index in Relation to Hospital Characteristics and Social Determinants of Health. 医院医疗高峰防范指数与医院特点及健康社会决定因素的关系分析
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-17 DOI: 10.1017/dmp.2025.10270
Philipp Lirk, David Marcozzi, Stephen Flynn, Paul C Kuo, Ricardo Pietrobon

Objective: Substantial investments have been made in hospital emergency preparedness. The Hospital Medical Surge Preparedness Index (HMSPI) has been proposed as a metric to assess health system readiness. This index summarizes hospital system characteristics, space and facilities, staff availability, and supply planning.

Methods: The primary objective was to evaluate the relationship between the HMSPI and characteristics of the respective hospitals, including size, type, location, performance on the Hospital Resilience Index (HRI), and Social Determinants of Health (SDoH).

Results: Higher HMSPI scores were found in suburban compared to rural hospitals, a higher HMSPI in larger hospitals with greater patient volumes and capacity (43.2 [42,44]) versus medium (26 [25,27]) and small (18 [17,19]) hospitals, and teaching status (29 [28,30]) versus non-teaching status (25 [25,26]). Investor-related hospitals and those caring for more patients with Medicare/Medicaid coverage had a lower HMSPI.

Conclusions: In conclusion, hospital medical surge preparedness is unevenly distributed across the U.S. health care system, with larger, not-for-profit, and teaching institutions having higher preparedness scores on the HMSPI, while a greater percentage of patients covered by Medicare/Medicaid is linked to lower scores.

目的:在医院应急准备方面进行了大量投资。医院医疗激增准备指数(HMSPI)已被提议作为一个指标来评估卫生系统的准备。该指数总结了医院系统特点、空间和设施、人员可用性和供应计划。方法:主要目的是评估HMSPI与各医院特征之间的关系,包括医院规模、类型、位置、医院恢复力指数(HRI)的表现和健康的社会决定因素(SDoH)。结果:郊区医院的HMSPI得分高于农村医院,患者数量和容量较大的大型医院(43.2[42,44])的HMSPI高于中型医院(26[25,27])和小型医院(18[17,19]),教学状态医院(29[28,30])高于非教学状态医院(25[25,26])。与投资者相关的医院和那些照顾更多医疗保险/医疗补助患者的医院的HMSPI较低。结论:总而言之,医院医疗应急准备在整个美国医疗保健系统中分布不均,大型非营利和教学机构在HMSPI上的准备得分较高,而医疗保险/医疗补助覆盖的患者比例较高,得分较低。
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引用次数: 0
Development of Public Information Material to Ensure Primary Protection Against Extreme Hot Weather Events. 编制公众资料,确保对极端炎热天气事件有初步防护。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-17 DOI: 10.1017/dmp.2025.10275
Nihal Dağ, Kerem Kinik, Cuneyt Caliskan

Aim: This study aimed to develop a slogan poster designed to systematically inform individuals and encourage protective actions against Extreme Hot Weather Events (EHWE).

Methods: A quasi-experimental single-group pretest-posttest design was employed, following the TREND guideline. EHWE knowledge was measured before exposure (Measurement 1), immediately after exposure (Measurement 2), and 2 months later (Measurement 3). Fifty-seven participants completed Measurements 1 and 2, and 45 completed all 3. Repeated-measures ANOVA and Bonferroni-adjusted pairwise comparisons were conducted; qualitative feedback was collected after Measurement 2.

Results: Knowledge scores increased from Measurement 1 (M = 9.36, SD = 2.39) to Measurement 2 (M = 13.93, SD = 0.94), then decreased at Measurement 3 (M = 12.07, SD = 1.80), while remaining above baseline. ANOVA confirmed a significant effect of time (F[2.88] = 129.13, P < 0.001, partial η2 = 0.70). Feedback indicated clarity and practicality, with suggestions for design improvements.

Conclusion: Poster exposure was associated with immediate knowledge gains, though a partial decline occurred by 2 months. Broader and controlled studies are needed to evaluate long-term effectiveness.

目的:本研究旨在设计一种标语海报,旨在系统地告知个人并鼓励对极端炎热天气事件(EHWE)采取保护行动。方法:采用准实验单组前测后测设计,遵循TREND指南。分别在暴露前(测量1)、暴露后立即(测量2)和2个月后(测量3)测量EHWE知识。57名参与者完成了测量1和2,45名完成了所有3项。采用重复测量方差分析和bonferroni校正两两比较;测量2后收集定性反馈。结果:知识得分从测量1 (M = 9.36, SD = 2.39)上升到测量2 (M = 13.93, SD = 0.94),然后在测量3 (M = 12.07, SD = 1.80)下降,但仍高于基线。方差分析证实了时间的显著影响(F[2.88] = 129.13, P < 0.001,偏η2 = 0.70)。反馈表明清晰和实用,并提出了改进设计的建议。结论:海报暴露与即时知识收获有关,尽管2个月后出现部分下降。需要更广泛的对照研究来评估长期有效性。
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引用次数: 0
Nuclear Disaster Medical Response and Preparedness: Perceived Radiation Risk in Ongoing Decommissioning Work and Future Strategies. 核灾难医疗反应和准备:正在进行的退役工作中的感知辐射风险和未来战略。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.54
Arifumi Hasegawa, Nobuyuki Hirohashi

This study aimed to assess the situations involving potential risks of over-exposure to radiation faced by workers during the decommissioning of the Fukushima Daiichi Nuclear Power Plant (FDNPP), and to prepare effective medical countermeasures. While deaths have occurred at regular intervals at the FDNPP site, they cannot be attributed to direct effects of radiation. Radiation exposure among decommissioning workers is strictly maintained within regulatory limits, and no deterministic or stochastic radiation effects have been observed. High-risk areas include the reactor buildings of Units 1-4 and the filtration systems for cooling water contaminated by decay heat from melted nuclear fuel. The reactor buildings contain a mix of α, β, and γ radionuclides, which may increase the need for medical responses specifically targeting α radionuclides in cases of internal contamination. With nuclear fuel removal in September 2024, there are growing concerns regarding the potential increase in radiation risks at the decommissioning site.

本研究旨在评估福岛第一核电站(FDNPP)退役期间工人所面临的辐射过度暴露的潜在风险,并准备有效的医疗对策。虽然在FDNPP场址定期发生死亡事件,但不能将其归因于辐射的直接影响。退役工人的辐射暴露被严格控制在规定范围内,没有观察到确定性或随机辐射效应。高风险区域包括1-4号机组的反应堆建筑和被熔化的核燃料衰变热污染的冷却水过滤系统。反应堆建筑物含有α、β和γ放射性核素的混合物,这可能会增加在内部污染情况下专门针对α放射性核素的医疗反应的需求。随着2024年9月核燃料的移除,人们越来越担心退役地点的辐射风险可能会增加。
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引用次数: 0
Overview of Recovery and Community-based Resilience in Fukushima from 2011 to 2023 After the Nuclear Power Plant Accident: Focusing on the Projects of Community-based Resilience. 2011 - 2023年福岛核电站事故后灾后恢复与社区复原力研究综述:以社区复原力项目为重点
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.24
Yurie Kobashi, Arifumi Hasegawa, Shunichi Yamashita

Objective: We aimed to describe representative activities related to radiation risk management and community-based revitalization in Fukushima following the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident by chronological phase and provide an overview of effective recovery projects and future prospects.

Methods: We systematically reviewed projects and research on the FDNPP accident in PubMed. For convenience, we defined the first, second, and third phases as 2011-2014, 2015-2018, and 2019-2023, respectively. The main project, purpose, organization, core location, and validation in each phase after the disaster were briefly summarized.

Results: We found that lessons learned from the FDNPP disaster have been continuously and professionally conveyed across generations, regions, and nations by effectively disseminating easy-to-understand information, avoiding any misunderstanding and prejudice. A continuous flow of scientists, researchers, and trainees from Japan and abroad to the affected areas will create a positive cycle of attracting people and residents, eventually accelerating recovery and contributing to the development of safe and vibrant communities in disaster-affected areas.

Conclusions: Continued efforts are required to enhance expertise at the field level, strengthen organizational capabilities, and promote international cooperation, thereby ensuring that a similar nuclear accident never happens again.

目的:我们旨在按时间顺序描述福岛第一核电站(FDNPP)事故后与辐射风险管理和社区振兴相关的代表性活动,并概述有效的恢复项目和未来前景。方法:系统回顾PubMed中关于FDNPP事故的项目和研究。为方便起见,我们将第一、第二和第三阶段分别定义为2011-2014年、2015-2018年和2019-2023年。简要总结灾后各阶段的主要项目、目的、组织、核心位置和验证。结果:我们发现,从FDNPP灾难中吸取的教训,通过有效地传播易于理解的信息,持续和专业地跨代、跨地区和跨国家传播,避免了任何误解和偏见。来自日本和海外的科学家、研究人员和受训人员源源不断地前往灾区,将形成一个积极的循环,吸引人员和居民,最终加速灾后恢复,并为灾区安全、充满活力的社区的发展做出贡献。结论:需要继续努力提高现场的专业知识,加强组织能力,促进国际合作,从而确保不再发生类似的核事故。
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引用次数: 0
Internal Dose Assessment in a Plutonium Internal Contamination Accident at JAEA's Oarai Research and Development Center. 日本原子能机构大井研究与发展中心钚内部污染事故的内部剂量评估。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.10049
Eunjoo Kim, Takako Tominaga, Kazuaki Yajima, Kotaro Tani, Chie Takada, Takumaro Momose, Hideo Tatsuzaki, Makoto Akashi, Osamu Kurihara

Objectives: On June 6, 2017, an accident occurred at the JAEA's Oarai Research and Development Center, where 5 workers inhaled plutonium. This study aims to evaluate the validity of the internal dose assessments conducted by the QST and to share the findings with the dosimetry community.

Methods: In vivo measurements (lungs and liver) and bioassays were performed. The particle size of the inhaled material was estimated based on the ratio of early fecal excretion to residual lung content. The absorption types of Pu and 241Am were evaluated using urinary excretion levels from bioassay results of early fecal and pre-Ca- DTPA urine samples.

Results: The estimated particle sizes of the inhaled materials were over 10 μm and several micrometers for 2 workers, respectively. The absorption types were evaluated as intermediate between M (Moderate) and S (Slow). A change in urinary excretion levels between before and after Ca-DTPA administration was observed, with the most significant reduction occurring after the initial treatment, followed by smaller changes.

Conclusions: The internal dose assessments for the 5 workers were confirmed to be conservatively conducted within a reasonable range. Comprehensive individual monitoring in cases of internal contamination by actinide is crucial to reducing uncertainties in dose assessment.

2017年6月6日,日本原子能机构大井研究开发中心发生事故,5名工人吸入钚。本研究旨在评估QST进行的内剂量评估的有效性,并与剂量学界分享研究结果。方法:进行体内测量(肺和肝)和生物测定。吸入物质的颗粒大小是根据早期粪便排泄与残留肺内容物的比例来估计的。通过早期粪便和ca - DTPA前尿液样本的生物测定结果的尿排泄水平来评估Pu和241Am的吸收类型。结果:2名工人吸入颗粒物的粒径分别大于10 μm和几微米。吸收类型介于M(中度)和S(缓慢)之间。观察到Ca-DTPA给药前后尿排泄水平的变化,在初始治疗后发生最显著的减少,其次是较小的变化。结论:确认5名工人的内剂量评估保守地在合理范围内进行。在锕系元素内部污染的情况下,全面的个人监测对于减少剂量评估的不确定性至关重要。
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引用次数: 0
Internal Contamination with Transuranium Radionuclides: Systematic Review on Assessment Methods and Diethylenetriamine Pentaacetate (DTPA) Treatment. 超铀放射性核素的内部污染:评价方法和五乙酸二乙烯三胺(DTPA)处理的系统综述。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.10224
Sehajpreet Gill, Lara Christianson, Steffen Dreger, Hajo Zeeb

Objective: Provide a systematic overview of assessment approaches for treatment decisions after internal contamination with plutonium, americium, or curium and the efficacy of decorporation treatment with diethylenetriamine pentaacetate (DTPA) among humans and animals.

Methods: MEDLINE, EMBASE, and Cochrane Library were searched until December 06, 2023. Controlled experimental animal studies and human studies were eligible. Hand search of relevant reports continued until December 24, 2024. Risk of bias was assessed with the OHAT and JBI critical appraisal tools. Narrative synthesis was performed.

Results: A total of 37 studies and 1 report were included. Two studies reported averted dose in humans following DTPA ranging from 150 μSv to 1.1 Sv, but the contribution of rapid contamination assessments to treatment decisions was unclear. Numerous outcomes across different treatment schedules and observation periods were studied in animal populations. Studies provided very low certainty evidence of positive treatment effects.

Conclusions: Whether rapid dose assessment contributes to timely treatment decisions could not be assessed with the limited amount of informative studies. In animal studies, DTPA treatment seems to be effective in reducing radiation burden and other proximal outcomes, but risk of bias is high. Evidence for humans is based on a small number of case studies where reductions in body burden have been reported.

目的:系统概述了钚、镅或curium内部污染后的处理决策评估方法,以及人与动物间用五乙酸二乙烯三胺(DTPA)去除污染的效果。方法:检索MEDLINE、EMBASE和Cochrane Library,检索截止日期为2023年12月6日。对照实验动物研究和人类研究均符合条件。相关报告手工检索持续到2024年12月24日。使用OHAT和JBI关键评估工具评估偏倚风险。进行叙事综合。结果:共纳入37篇研究和1篇报道。两项研究报告了DTPA后人类避免的剂量从150 μSv到1.1 μSv不等,但快速污染评估对治疗决策的贡献尚不清楚。在动物种群中研究了不同治疗方案和观察期的许多结果。研究提供了非常低的确定性证据证明积极的治疗效果。结论:由于信息量有限,无法评估快速剂量评估是否有助于及时做出治疗决定。在动物研究中,DTPA治疗似乎在减少辐射负担和其他近端结果方面有效,但偏倚风险很高。对人类的证据是基于少数案例研究,这些研究报告了身体负担的减轻。
{"title":"Internal Contamination with Transuranium Radionuclides: Systematic Review on Assessment Methods and Diethylenetriamine Pentaacetate (DTPA) Treatment.","authors":"Sehajpreet Gill, Lara Christianson, Steffen Dreger, Hajo Zeeb","doi":"10.1017/dmp.2025.10224","DOIUrl":"10.1017/dmp.2025.10224","url":null,"abstract":"<p><strong>Objective: </strong>Provide a systematic overview of assessment approaches for treatment decisions after internal contamination with plutonium, americium, or curium and the efficacy of decorporation treatment with diethylenetriamine pentaacetate (DTPA) among humans and animals.</p><p><strong>Methods: </strong>MEDLINE, EMBASE, and Cochrane Library were searched until December 06, 2023. Controlled experimental animal studies and human studies were eligible. Hand search of relevant reports continued until December 24, 2024. Risk of bias was assessed with the OHAT and JBI critical appraisal tools. Narrative synthesis was performed.</p><p><strong>Results: </strong>A total of 37 studies and 1 report were included. Two studies reported averted dose in humans following DTPA ranging from 150 μSv to 1.1 Sv, but the contribution of rapid contamination assessments to treatment decisions was unclear. Numerous outcomes across different treatment schedules and observation periods were studied in animal populations. Studies provided very low certainty evidence of positive treatment effects.</p><p><strong>Conclusions: </strong>Whether rapid dose assessment contributes to timely treatment decisions could not be assessed with the limited amount of informative studies. In animal studies, DTPA treatment seems to be effective in reducing radiation burden and other proximal outcomes, but risk of bias is high. Evidence for humans is based on a small number of case studies where reductions in body burden have been reported.</p>","PeriodicalId":54390,"journal":{"name":"Disaster Medicine and Public Health Preparedness","volume":"19 ","pages":"e346"},"PeriodicalIF":1.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Centers for Disease Control and Prevention Communication Products, Tools, and Training for Radiological Emergency Preparedness. 疾病控制和预防中心,辐射应急准备的通讯产品、工具和培训。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.21
Adela Salame-Alfie

The mission of the Radiation Studies Program (RSP) in the Centers for Disease Control and Prevention, National Center for Environmental Health, is to analyze scientific advances, educate the public, and build public health capacity for all communities in the US to reduce morbidity and mortality from unnecessary exposures to radiation-both in daily life and in the event of a radiation emergency. The program accomplishes these goals by collaborating with national and international partners and supporting scientific advancements in collaboration with national and international organizations.Since 2001, RSP has developed tools, training, and communication products to prepare and support local, state, tribal, and federal agencies in the US that are engaged in a response to a nuclear or radiological incident. This paper summarizes the latest RSP resources, which were presented during the 17th REMPAN Coordination Meeting in Seoul, South Korea, on September 14, 2023.

国家环境卫生中心疾病控制和预防中心的辐射研究计划(RSP)的使命是分析科学进展,教育公众,并为美国所有社区建立公共卫生能力,以减少在日常生活和辐射紧急情况下不必要暴露于辐射的发病率和死亡率。该计划通过与国家和国际合作伙伴合作,并与国家和国际组织合作支持科学进步来实现这些目标。自2001年以来,RSP开发了工具、培训和通信产品,以准备和支持美国从事核或辐射事件响应的地方、州、部落和联邦机构。本文总结了2023年9月14日在韩国首尔举行的第17届REMPAN协调会议上提交的最新RSP资源。
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引用次数: 0
National System of Medical Preparedness and Response to Radiation Emergencies in Korea: Current Status and Sustainable Development. 韩国辐射紧急情况的国家医疗准备和响应系统:现状和可持续发展。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.43
Haewon Kong, Songwon Seo, Eun Shil Cha, Min Seok Park, Yanghee Lee, Ki Moon Seong, Jungjin Kim, Kyung Hwan Park, Geum Cheol Jeong, Seung Bum Lee, Won Il Jang, Mihyun Yang, Sunsil Kim, Minsu Cho

Objectives: This article provides an overview of Korea's National Radiological Emergency Medical System, which coordinates medical responses to radiological emergencies through specialized infrastructure, training, and research.

Methods: The system's recent advancements are outlined, focusing on a nationwide network of emergency medical institutions and improvements in education, training, and research to enhance preparedness for radiological emergencies.

Results: The National Radiation Emergency Medical Center (NREMC) manages 31 designated emergency medical institutions, providing specialized training for first responders and medical personnel. Virtual reality tools have been integrated into training programs to improve instructional effectiveness. A hotline offers immediate support for radiation exposure cases and public consultations during non-emergency periods. Additionally, the NREMC employs internationally accredited physical and biological dosimetry methods and strengthens its expertise through collaborations with global organizations.

Conclusions: Continuous advancements in medical response, training, and international cooperation enhance Korea's radiological emergency preparedness. Ongoing research and technology integration ensure effective emergency interventions and long-term public health protection.

目的:本文概述了韩国的国家放射紧急医疗系统,该系统通过专门的基础设施、培训和研究协调对放射紧急情况的医疗反应。方法:概述了该系统的最新进展,重点是全国紧急医疗机构网络和教育、培训和研究方面的改进,以加强对放射性紧急情况的准备。结果:国家辐射应急医疗中心(NREMC)管理着31家定点应急医疗机构,对急救人员和医务人员进行了专业培训。虚拟现实工具已被整合到培训计划中,以提高教学效率。热线在非紧急期间为辐射个案和公众谘询提供即时支援。此外,NREMC采用国际认可的物理和生物剂量测定方法,并通过与全球组织的合作加强其专业知识。结论:医疗反应、培训和国际合作的不断进步增强了韩国的放射性应急准备。正在进行的研究和技术整合确保了有效的紧急干预和长期的公共健康保护。
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引用次数: 0
EURADOS/REMPAN Review on Monitoring and Dosimetry for Radionuclide-contaminated Wounds. EURADOS/REMPAN放射性核素污染伤口监测和剂量学综述。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.10092
María Antonia López, Arlene Alves, Maia Avtandilashvili, Luiz Bertelli, Sara Dumit, Pavel Fojtík, Didier Franck, Milan Gadd, Luke Hetrick, John Klumpp, Chunsheng Li, Juan Francisco Navarro Amaro, Jakub Ośko, Begoña Pérez López, Fabrice Petitot, Deepesh Poudel, Anthony Riddell, Martin Šefl, Steve Sugarman, Sergey Tolmachev, David Broggio

The European Radiation Dosimetry Group (EURADOS) and the WHO's Radiation Emergency Medical Preparedness and Assistance Network (REMPAN) have collaborated to review best practices for managing radionuclide intakes through wounds. Rapid response and decisions on wound decontamination, tissue excision, and chelation therapy are based on measurements of the exposed individual and preliminary dose assessments using reasonable default assumptions. The goal is to minimize exposure, prevent tissue reactions, and reduce the risk of stochastic effects.The management of a contaminated wound is always case-specific, but some general procedures typically apply for a proper evaluation of the contamination case. Medical doctors (surgeons and toxicologists) and internal dosimetrists should work together in the management of the contaminated wound case, with internal dosimetrists providing expert advice to aid clinical decision-making and communication with the patient and his/her family. The ISO standard 20031:2020 provides guidelines on the monitoring and dosimetry for internal exposures due to wound contamination with radionuclides. The Clinical Decision Guide was proposed by the National Council on Radiation Protection and Measurements in its Report 161 to assist physicians in making treatment decisions for individuals with internal radionuclide intakes. Best practices for medical treatment, based on previous experience, are presented here.

欧洲辐射剂量学小组(EURADOS)和世卫组织的辐射应急医疗准备和援助网络(REMPAN)合作审查了管理通过伤口摄入放射性核素的最佳做法。伤口消毒、组织切除和螯合治疗的快速反应和决策是基于对暴露个体的测量和使用合理默认假设的初步剂量评估。目标是尽量减少暴露,防止组织反应,减少随机效应的风险。污染伤口的处理总是根据具体情况而定,但一些一般程序通常适用于对污染病例的适当评估。医生(外科医生和毒理学家)和内部剂量师应共同努力处理受污染的伤口病例,由内部剂量师提供专家意见,协助临床决策和与患者及其家属的沟通。ISO标准20031:2020提供了放射性核素伤口污染引起的内部照射监测和剂量测定指南。临床决策指南是由国家辐射防护和测量委员会在其报告161中提出的,目的是帮助医生为体内摄入放射性核素的患者做出治疗决定。本文介绍了基于以往经验的医疗最佳做法。
{"title":"EURADOS/REMPAN Review on Monitoring and Dosimetry for Radionuclide-contaminated Wounds.","authors":"María Antonia López, Arlene Alves, Maia Avtandilashvili, Luiz Bertelli, Sara Dumit, Pavel Fojtík, Didier Franck, Milan Gadd, Luke Hetrick, John Klumpp, Chunsheng Li, Juan Francisco Navarro Amaro, Jakub Ośko, Begoña Pérez López, Fabrice Petitot, Deepesh Poudel, Anthony Riddell, Martin Šefl, Steve Sugarman, Sergey Tolmachev, David Broggio","doi":"10.1017/dmp.2025.10092","DOIUrl":"https://doi.org/10.1017/dmp.2025.10092","url":null,"abstract":"<p><p>The European Radiation Dosimetry Group (EURADOS) and the WHO's Radiation Emergency Medical Preparedness and Assistance Network (REMPAN) have collaborated to review best practices for managing radionuclide intakes through wounds. Rapid response and decisions on wound decontamination, tissue excision, and chelation therapy are based on measurements of the exposed individual and preliminary dose assessments using reasonable default assumptions. The goal is to minimize exposure, prevent tissue reactions, and reduce the risk of stochastic effects.The management of a contaminated wound is always case-specific, but some general procedures typically apply for a proper evaluation of the contamination case. Medical doctors (surgeons and toxicologists) and internal dosimetrists should work together in the management of the contaminated wound case, with internal dosimetrists providing expert advice to aid clinical decision-making and communication with the patient and his/her family. The ISO standard 20031:2020 provides guidelines on the monitoring and dosimetry for internal exposures due to wound contamination with radionuclides. The Clinical Decision Guide was proposed by the National Council on Radiation Protection and Measurements in its Report 161 to assist physicians in making treatment decisions for individuals with internal radionuclide intakes. Best practices for medical treatment, based on previous experience, are presented here.</p>","PeriodicalId":54390,"journal":{"name":"Disaster Medicine and Public Health Preparedness","volume":"19 ","pages":"e353"},"PeriodicalIF":1.8,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in Biological Dose Assessment for Radiation Emergency Medicine in the Korea Institute of Radiological and Medical Sciences. 韩国放射医学研究所放射急诊医学生物剂量评估进展。
IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2025-12-12 DOI: 10.1017/dmp.2025.41
Ki Moon Seong, Minsu Cho, Jin Kyung Lee

Accurate radiation dose measurement is crucial for medical intervention and protective actions. Biological dose assessment directly measures radiation-induced molecular and physiological changes, providing information about the absorbed dose and potential health risks. The Korea Institute of Radiological and Medical Sciences (KIRAMS) has performed biological dosimetry using cytogenetic assays since 2010. These assays are used for individual dose estimation in various situations, including occupational exposure, accidental radiation exposure, and health risk assessment of people living near nuclear power plants in Korea. Recent advancements in biological dose assessment methods, such as automated scoring and high-throughput assays, have improved efficiency and enabled more people to undergo dose assessment. The KIRAMS continuously explores new methods and targets for biodosimetry to enhance dose assessment capabilities and can contribute to expand the biological dose assessment capacity with the expertise and facilities, responding to large-scale accidents of radiation exposure in the world.

准确的辐射剂量测量对医疗干预和防护行动至关重要。生物剂量评估直接测量辐射引起的分子和生理变化,提供有关吸收剂量和潜在健康风险的信息。韩国放射医学研究所(KIRAMS)自2010年以来一直使用细胞遗传学分析进行生物剂量测定。这些测定法用于各种情况下的个人剂量估计,包括对韩国核电站附近居民的职业照射、意外辐射照射和健康风险评估。生物剂量评估方法的最新进展,如自动评分和高通量分析,提高了效率,使更多的人能够接受剂量评估。KIRAMS不断探索新的生物剂量学方法和靶点,提高剂量评估能力,以专业知识和设施为扩大生物剂量评估能力做出贡献,以应对世界范围内的大规模辐射暴露事故。
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引用次数: 0
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