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Occupational asthma induced by fish exposure. 接触鱼类引起的职业性哮喘。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-30 DOI: 10.1093/occmed/kqad127
B Añibarro, L Feijoo, N de Las Cuevas, F J Seoane

Occupational asthma triggered by inhaling fish-derived aerosols is estimated to affect 2-8% of exposed individuals. This primarily affects workers in the fish processing industry. Fishmongers, rarely experience this issue, as recent research found no significant difference in asthma rates compared to a control group. We report the case of a fishmonger who presented with a 1-year history of rhinoconjunctivitis and asthma. The patient attributed these symptoms to his occupational exposure within the fish market environment, which worsened in the cold storage warehouse. Symptoms improved during holidays. Diagnosis involved skin-prick tests, sIgE (ImmunoCAP-specific IgE) measurements, and bronchial challenge tests, confirming occupational asthma from fish bioaerosol exposure. Parvalbumins, common fish proteins, share structural similarities, leading to cross-reactivity in fish allergy sufferers. In this case, sensitivity to rGad c1 (cod parvalbumin) was identified as the primary trigger for the patient's asthma, and responsible for sensitizations observed across various tested fish species.

据估计,2-8%的接触者因吸入鱼源气溶胶而引发职业性哮喘。这主要影响鱼类加工业的工人。鱼贩很少遇到这个问题,因为最近的研究发现,与对照组相比,他们的哮喘发病率没有显著差异。我们报告的情况下,鱼贩谁提出了1年的历史鼻结膜炎和哮喘。患者将这些症状归因于他在鱼市环境中的职业暴露,并在冷库中恶化。假期期间症状有所改善。诊断包括皮肤点刺试验、sIgE(免疫cap特异性IgE)测量和支气管激发试验,证实了鱼类生物气溶胶暴露引起的职业性哮喘。小鱼蛋白是一种常见的鱼类蛋白质,它们的结构相似,导致鱼类过敏患者产生交叉反应。在这种情况下,对rGad c1(鳕鱼小白蛋白)的敏感性被确定为患者哮喘的主要触发因素,并负责在各种测试鱼类中观察到的致敏。
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引用次数: 0
Shaping the stress consultation in Occupational Health. 塑造职业健康中的压力咨询。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-30 DOI: 10.1093/occmed/kqad073
John Sterland
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引用次数: 0
News from SOM and OM calendar. 来自 SOM 的新闻和 OM 日历。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-30 DOI: 10.1093/occmed/kqad152
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引用次数: 0
Mental health and vitality predict spinal pain in healthcare workers. 心理健康和活力可预测医护人员的脊柱疼痛。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1093/occmed/kqad096
A Espin, R Núñez-Cortés, J Irazusta, A Rodriguez-Larrad, J Torres-Unda, J Vinstrup, M D Jakobsen, L L Andersen

Background: Despite extensive investigation of ergonomic risk factors for spinal pain in healthcare workers, limited knowledge of psychological risk factors exists.

Aims: To assess the prospective association of mental health and vitality with development of spinal pain in healthcare workers.

Methods: A prospective cohort study was carried out involving 1950 healthcare workers from 19 hospitals in Denmark. Assessments were done at baseline and at 1-year follow-up. Mental health and vitality were measured using the Short Form-36 Health Survey, while spinal pain intensity was measured using a 0-10 scale in the low-back, upper-back and neck, respectively. Cumulative logistic regressions adjusted for several confounding factors were applied, reporting risk estimates as odds ratios (ORs) and 95% confidence intervals (CIs).

Results: Using good mental health as reference, moderate (but not poor) mental health at baseline was associated with increased pain intensity in the low-back (OR: 1.41 [95% CI: 1.21-1.77]), upper-back (OR: 1.63 [95% CI: 1.31-2.02]) and neck (OR: 1.31 [95% CI: 1.07-1.61]) at 1-year follow-up. Likewise, using high vitality as reference, both moderate and low vitality at baseline were associated with increased pain intensity in the low-back (OR: 1.54 [95% CI: 1.22-1.94] and OR: 2.34 [95% CI: 1.75-3.12], respectively), upper-back (OR: 1.72 [95% CI: 1.34-2.23] and OR: 2.46 [95% CI: 1.86-3.25], respectively) and neck (OR: 1.66 [95% CI: 1.34-2.06] and OR: 2.06 [95% CI: 1.61-2.63], respectively) at 1-year follow-up.

Conclusions: Compared to healthcare workers with good mental health and high vitality, those with moderate mental health and low/moderate vitality, respectively, were more likely to increase spinal pain intensity at 1-year follow-up. These components should also be considered in the prevention of spinal pain in healthcare workers.

背景:目的:评估心理健康和活力与医护人员脊柱疼痛发生的前瞻性关联:方法:对丹麦 19 家医院的 1950 名医护人员进行了前瞻性队列研究。在基线和随访 1 年时进行了评估。心理健康和活力采用短表-36健康调查进行测量,脊柱疼痛强度采用0-10分制,分别测量腰部、上背部和颈部的疼痛程度。采用累积逻辑回归法对几种混杂因素进行调整,以几率比(OR)和95%置信区间(CI)的形式报告风险估计值:以良好的心理健康状况为参照,基线心理健康状况中等(而非较差)与随访一年时腰背部(OR:1.41 [95% CI:1.21-1.77])、上背部(OR:1.63 [95% CI:1.31-2.02])和颈部(OR:1.31 [95% CI:1.07-1.61])疼痛强度增加有关。同样,以高活力为参照,基线活力为中度和低度时,腰背部疼痛强度增加(OR:1.54 [95% CI:1.22-1.94] 和 OR:2.34 [95% CI:1.75-3.12]),上背部疼痛强度增加(OR:1.63 [95% CI:1.31-2.02]),颈部疼痛强度增加(OR:1.31 [95% CI:1.07-1.61])。12])、上背部(OR:1.72 [95% CI:1.34-2.23]和 OR:2.46 [95% CI:1.86-3.25])和颈部(OR:1.66 [95% CI:1.34-2.06]和 OR:2.06 [95% CI:1.61-2.63])的疼痛强度:结论:与精神健康状况良好和活力较高的医护人员相比,精神健康状况中等和活力较低/中等的医护人员在 1 年随访时脊柱疼痛强度更有可能增加。在预防医护人员脊柱疼痛时也应考虑这些因素。
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引用次数: 0
Long-term occupational exposures on disability-free survival and mortality in older adults. 长期职业暴露对老年人无残疾生存和死亡率的影响。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1093/occmed/kqad105
S M Alif, G P Benke, H Kromhout, R Vermeulen, C Tran, K Ronaldson, K Walker-Bone, R Woods, L Beilin, A Tonkin, A J Owen, J J McNeil

Background: The impact of long-term occupational exposures on health in older adults is increasingly relevant as populations age. To date, no studies have reported their impact on survival free of disability in older adults.

Aims: We aimed to investigate the association between long-term occupational exposure and disability-free survival (DFS), all-cause mortality and cause-specific mortality in initially healthy older adults.

Methods: We analysed data from 12 215 healthy participants in the ASPirin in Reducing Events in the Elderly (ASPREE) study whose mean age was 75 years. Their work history was collated with the 'ALOHA-plus JEM' (Job Exposure Matrix) to assign occupational exposures. The primary endpoint, DFS, was a composite measure of death, dementia or persistent physical disability. The secondary endpoint, mortality, was classified according to the underlying cause. Cox proportional hazard models were used to calculate hazard ratios and 95% confidence intervals, adjusted for confounders.

Results: A total of 1835 individuals reached the DFS endpoint during the median 4.7 years follow-up period. Both ever-high and cumulative exposure to all dusts and all pesticides during a person's working years were associated with reduced DFS. Compared to no exposure, men with high exposure to dusts and pesticides had a reduced DFS. Neither of these exposures were significantly associated with all-cause mortality. Men with high occupational exposure to solvents and women exposed to dusts experienced higher all-cause and cancer-related mortality.

Conclusions: Long-term occupational exposure to all dusts and pesticides was associated with a reduced DFS and increased mortality in community-dwelling healthy older adults.

背景:随着人口老龄化,长期职业暴露对老年人健康的影响越来越重要。到目前为止,还没有研究报告它们对老年人无残疾生存的影响。目的:我们旨在调查长期职业暴露与最初健康的老年人的无残疾生存率(DFS)、全因死亡率和病因特异性死亡率之间的关系。方法:我们分析了12 215名平均年龄为75岁的ASPirin减少老年人事件(ASPREE)研究的健康参与者。他们的工作史与“ALOHA+JEM”(工作暴露矩阵)进行了核对,以分配职业暴露。主要终点DFS是死亡、痴呆或持续性身体残疾的综合指标。次要终点死亡率根据根本原因进行分类。Cox比例风险模型用于计算风险比和95%置信区间,并对混杂因素进行了调整。结果:在中位4.7年的随访期内,共有1835人达到DFS终点。在一个人工作期间,接触所有灰尘和杀虫剂的次数和累积次数都与DFS减少有关。与未接触相比,高接触灰尘和杀虫剂的男性DFS降低。这两种接触均与全因死亡率无显著相关性。高职业暴露于溶剂的男性和暴露于粉尘的女性经历了更高的全因死亡率和癌症相关死亡率。结论:在社区居住的健康老年人中,长期职业接触所有灰尘和杀虫剂与DFS降低和死亡率增加有关。
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引用次数: 0
Occupational injuries in workers of a Spanish bank. 西班牙一家银行工人的职业伤害。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1093/occmed/kqad116
L Reinoso-Barbero, L Pardillos, M-C Romero-Paredes, R Díaz-Garrido, J-M Mendiguren, A Gieco, F Gómez-Gallego

Background: In 2017, 69 108 work-related traffic injuries with medical leave were documented, constituting 12% of all occupational injuries (OI) in Spain.

Aims: The aim of this study was to describe OI within a Spanish bank company during 2017.

Methods: A cross-sectional analysis was conducted using the company's mandatory OI records, presenting data in both absolute (n) and relative (%) frequencies. The chi-square test was employed for comparisons.

Results: Among the company's 10 399 employees, 176 OI cases were recorded. Most were minor musculoskeletal incidents, with one severe myocardial infarction and one mild anxiety episode. Lower limb injuries were the most prevalent. Injuries of the trunk (P < 0.001), neck (P < 0.05), and upper limbs (P < 0.001) were linked to workplace factors. Approximately 62% of OI occurred outside the workplace and resulted in more extended medical leave (P < 0.01). Traffic-related injuries accounted for 39% of OI cases and caused 49% of days lost due to OI (P < 0.001).Female gender (P < 0.001) and age over 40 years (P < 0.05) were significantly associated with OI.

Conclusions: In our study, musculoskeletal injuries were the most common, with a single cardiovascular event being the most severe. OI occurring outside the workplace was more frequent and led to longer medical leaves. Notably, traffic-related injuries were especially significant, exceeding official statistics 4-fold.

背景:2017年,西班牙记录了69 108起工伤事故,占西班牙所有工伤事故(OI)的12%。目的:本研究的目的是描述2017年西班牙银行公司内部的OI。方法:使用该公司的强制性OI记录进行横断面分析,显示绝对(n)和相对(%)频率的数据。比较采用卡方检验。结果:在公司10399名员工中,记录有176例OI病例。大多数是轻微的肌肉骨骼事件,有一个严重的心肌梗死和一个轻微的焦虑发作。下肢损伤最为常见。结论:在我们的研究中,肌肉骨骼损伤最为常见,单一心血管事件最为严重。在工作场所以外发生的成骨不全更频繁,导致病假时间更长。值得注意的是,与交通有关的伤害尤其严重,超过官方统计数字的4倍。
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引用次数: 0
Non-fatal injuries among police officers during use-of-force encounters. 警察在使用武力时受非致命伤。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1093/occmed/kqad101
E R Maguire, E A Paoline

Background: Occupational injuries are common in police work due to routine exposure to conflict, violence, accidents, and other hazards. However, little is known about the factors associated with non-fatal job-related injuries among police officers.

Aims: To study the factors associated with non-fatal job-related injuries among Tucson, AZ, police officers during encounters involving the use of force.

Methods: Data were analysed on all use-of-force cases involving Tucson police officers from January 2018 through June 2020. Logistic regression models were used to assess the factors that influence the likelihood of officer injuries.

Results: Overall, about 11% of officers involved in a use-of-force encounter were injured. Multivariate analyses reveal that defensive physical resistance by the suspect increases injury risk among officers. When suspects assault officers or others during the encounter, the risk of officer injury also increases significantly. Certain types of force used by police, such as hands-on tactics and TASER use are also associated with increased risk of injury among officers. The age and race of the suspect are not associated with the likelihood of injury among officers.

Conclusions: Certain suspect behaviours and use-of-force modalities increase the risk of injury among officers. Understanding these risk factors can help employers put in place appropriate measures to reduce the risk of occupational injuries among police officers.

背景:由于日常暴露在冲突、暴力、事故和其他危险中,职业伤害在警察工作中很常见。然而,人们对警察非致命性工伤的相关因素知之甚少。目的:研究亚利桑那州图森市警察在遭遇使用武力时非致命性工伤的相关因素。方法:分析2018年1月至2020年6月涉及图森市警察的所有使用武力案件的数据。使用Logistic回归模型来评估影响军官受伤可能性的因素。结果:总的来说,大约11%的警察在使用武力时受伤。多因素分析显示,嫌疑人的防御性身体抵抗增加了警察受伤的风险。当嫌疑人在遭遇过程中袭击警察或其他人时,警察受伤的风险也会显著增加。警察使用的某些类型的武力,如动手战术和TASER的使用,也会增加警察受伤的风险。嫌疑人的年龄和种族与警察受伤的可能性无关。结论:某些可疑行为和使用武力的方式增加了警官受伤的风险。了解这些风险因素可以帮助雇主采取适当措施,降低警察职业伤害的风险。
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引用次数: 0
Reply. 答复
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1093/occmed/kqad113
Feiko J M de Jong, Thijs T Wingelaar, Rob A van Hulst
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引用次数: 0
Management standards and burnout among surgeons in the United Kingdom. 英国外科医生的管理标准和倦怠。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1093/occmed/kqad102
J Houdmont, P Daliya, A Adiamah, E Theophilidou, J Hassard, D N Lobo

Background: Burnout arising from chronic work-related stress is endemic among surgeons in the UK. Identification of contributory and modifiable psychosocial work characteristics could inform risk reduction activities.

Aims: We aimed to assess the extent to which surgeons' psychosocial working conditions met aspirational Management Standards delineated by the UK Health and Safety Executive, draw comparisons with national general workforce benchmarks and explore associations with burnout.

Methods: Surgeons (N = 536) completed the Management Standards Indicator Tool and a single-item measure of burnout. Descriptive data were computed for each Standard, independent t-tests were used to examine differences between trainees and consultants, and hierarchical linear regression was applied to explore relations between psychosocial work environment quality and burnout.

Results: Psychosocial work environment quality fell short of each Management Standard. Trainee surgeons (n = 214) reported significantly poorer psychosocial working conditions than consultant surgeons (n = 322) on the control, peer support and change Standards. When compared with UK workforce benchmarks, trainees' psychosocial working conditions fell below the 10th percentile on four Standards and below the 50th percentile on the remainder. Consultant surgeons were below the 50th percentile on five of the seven Standards. Psychosocial working conditions accounted for 35% of the variance in burnout over that accounted for by socio- and occupational-demographic characteristics.

Conclusions: Surgeons' psychosocial working conditions were poor in comparison with benchmark data and associated with burnout. These findings suggest that risk management activities based on the Management Standards approach involving modification of psychosocial working conditions would help to reduce burnout in this population.

背景:在英国,由慢性工作压力引起的倦怠在外科医生中很普遍。确定有贡献和可改变的心理社会工作特征可以为降低风险活动提供信息。目的:我们旨在评估外科医生的心理社会工作条件在多大程度上符合英国健康与安全执行局制定的理想管理标准,与全国普通劳动力基准进行比较,并探讨与倦怠的关系。方法:外科医生(N = 536)完成了管理标准指标工具和倦怠的单项测量。计算每个标准的描述性数据,使用独立的t检验来检验受训者和顾问之间的差异,并应用层次线性回归来探索心理社会工作环境质量与倦怠之间的关系。结果:心理社会工作环境质量达不到各项管理标准要求。实习外科医生(n = 214)报告的心理社会工作条件明显比顾问外科医生差(n = 322)关于控制、对等支持和改变标准。与英国劳动力基准相比,受训人员的心理社会工作条件在四项标准中低于第10个百分点,在其余标准中低于50个百分点。在七项标准中,有五项低于第50百分位。与社会和职业人口统计特征相比,心理社会工作条件占倦怠差异的35%。结论:与基准数据相比,外科医生的心理社会工作条件较差,并与倦怠有关。这些发现表明,基于管理标准方法的风险管理活动,包括改变心理社会工作条件,将有助于减少这一人群的倦怠。
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引用次数: 0
Hydrogen cyanamide exposure: a case series from Pavia Poison Control Centre. 氰胺暴露:帕维亚毒物控制中心的一系列病例。
IF 5.1 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-12-29 DOI: 10.1093/occmed/kqad108
L Bernasconi, M Carnovale, D Lonati, V M Petrolini, A Schicchi, B Brolli, V M Negrini, C Grazioli, O Maystrova, E Buscaglia, Giulia Scaravaggi, F Crema, C A Locatelli

Background: Hydrogen cyanamide is a plant growth regulator introduced in Italy as Dormex in 2000, but recalled from the market in 2008. It's currently not authorized in Europe. Inhalation/dermal contact may cause irritation/caustic burns, ingestion of severe organ damage and concomitant alcohol consumption disulfiram-like reaction due to aldehyde-dehydrogenase inhibition by hydrogen cyanamide.

Aims: To study all exposure cases referred to our centre, evaluating temporal and geographic distribution and analysing clinical manifestations, including the ones after alcohol consumption.

Methods: We retrospectively evaluated all hydrogen cyanamide exposures referred to our Poison Control Centre (January 2007-December 2021). For each case, age, sex, exposure route/year, geographical location, intent of exposure, alcohol co-ingestion, emergency department-admission Poison Severity Score, signs/symptoms and treatment were analysed.

Results: Thirty subjects were included. Median case/year was 1 [1; 2]: 79% occurred after market withdrawal, 92% in Sicily. All exposures were unintentional and work related; 41% of patients also co-ingested alcohol. Mean poison severity score at emergency department admission was 1.54, more severe when ingestion occurred. The most common signs/symptoms were flushing, secondary to peripheral vasodilation (41%), hyperaemia/erythema (29%), dyspnoea (25%), nausea (20%), vomiting (12%), oedema (12%), II-III degrees burns (12%) and pharyngodynia (12%). All patients were treated symptomatically and fully recovered.

Conclusions: Hydrogen cyanamide exposure can lead to severe clinical manifestations. Despite its withdrawal from the Italian market, hydrogen cyanamide is still used: through PCC's crucial role in monitoring exposure to agricultural products efforts should be made to contrast illegal trade and increase awareness of its potential toxicity in those countries in which it's still legal.

背景:氰胺氢是一种植物生长调节剂,于2000年在意大利以Dormex的名义引入,但于2008年从市场上召回。它目前未在欧洲获得授权。吸入/皮肤接触可能会引起刺激/腐蚀性烧伤,摄入严重的器官损伤,以及由于氰胺对乙醛脱氢酶的抑制而伴随的饮酒双硫仑样反应。目的:研究转介至我们中心的所有暴露病例,评估时间和地理分布,并分析临床表现,包括饮酒后的表现。方法:我们回顾性评估了我们毒物控制中心(2007年1月至2021年12月)的所有氰胺暴露。对每个病例的年龄、性别、接触途径/年、地理位置、接触意图、共同饮酒、急诊科入院毒物严重程度评分、体征/症状和治疗进行了分析。结果:纳入30名受试者。中位病例/年为1[1;2]:79%发生在市场退出后,西西里岛为92%。所有暴露都是无意的,与工作有关;41%的患者同时摄入酒精。急诊科入院时的平均中毒严重程度评分为1.54,摄入时更严重。最常见的体征/症状是潮红、继发于外周血管舒张(41%)、充血/红斑(29%)、呼吸困难(25%)、恶心(20%)、呕吐(12%)、水肿(12%),Ⅱ-Ⅲ度烧伤(12%)和咽痛(12%)。所有患者均接受了症状治疗并完全康复。结论:氰胺暴露可导致严重的临床表现。尽管氰胺已退出意大利市场,但它仍在使用:通过PCC在监测农产品暴露方面的关键作用,应努力在那些仍然合法的国家对比非法贸易,提高对其潜在毒性的认识。
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引用次数: 0
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