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IF 1 4区 数学 Q2 Mathematics Pub Date : 2021-01-01 DOI: 10.1016/b978-0-12-819880-3.00003-2
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引用次数: 0
A new model for the emergence of blood capillary networks 毛细血管网络出现的新模型
IF 1 4区 数学 Q2 Mathematics Pub Date : 2020-12-21 DOI: 10.3934/nhm.2021001
Pedro Aceves-Sanchez, Benjamin Aymard, Diane Peurichard, Pol Kennel, Anne Lorsignol, Franck Plouraboué, Louis Casteilla, Pierre Degond
We propose a new model for the emergence of blood capillary networks. We assimilate the tissue and extra cellular matrix as a porous medium, using Darcy's law for describing both blood and interstitial fluid flows. Oxygen obeys a convection-diffusion-reaction equation describing advection by the blood, diffusion and consumption by the tissue. Discrete agents named capillary elements and modelling groups of endothelial cells are created or deleted according to different rules involving the oxygen concentration gradient, the blood velocity, the sheer stress or the capillary element density. Once created, a capillary element locally enhances the hydraulic conductivity matrix, contributing to a local increase of the blood velocity and oxygen flow. No connectivity between the capillary elements is imposed. The coupling between blood, oxygen flow and capillary elements provides a positive feedback mechanism which triggers the emergence of a network of channels of high hydraulic conductivity which we identify as new blood capillaries. We provide two different, biologically relevant geometrical settings and numerically analyze the influence of each of the capillary creation mechanism in detail. All mechanisms seem to concur towards a harmonious network but the most important ones are those involving oxygen gradient and sheer stress. A detailed discussion of this model with respect to the literature and its potential future developments concludes the paper.
我们为毛细血管网络的出现提出了一个新的模型。我们吸收组织和细胞外基质作为多孔介质,使用达西定律来描述血液和间质液流动。氧气服从一个对流-扩散-反应方程,描述血液的平流,组织的扩散和消耗。根据不同的规则(包括氧浓度梯度、血流速度、绝对应力或毛细血管元件密度)创建或删除被称为毛细血管元件和内皮细胞建模组的离散因子。一旦创建,毛细血管元件局部增强液压传导矩阵,有助于局部增加血液速度和氧气流量。毛细管元件之间没有连接性。血液、氧气流动和毛细血管元素之间的耦合提供了一种正反馈机制,该机制触发了高水力传导性通道网络的出现,我们将其识别为新的毛细血管。我们提供了两种不同的、生物学上相关的几何设置,并对每种毛细管形成机制的影响进行了详细的数值分析。所有的机制似乎都朝着一个和谐的网络发展,但最重要的是那些涉及氧梯度和纯粹压力的机制。关于该模型的文献及其潜在的未来发展的详细讨论结束了本文。
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引用次数: 0
EEG-based functional brain networks: hemispheric differences in males and females 基于脑电图的功能性脑网络:男性和女性的半球差异
IF 1 4区 数学 Q2 Mathematics Pub Date : 2015-02-01 DOI: 10.3934/NHM.2015.10.223
M. Jalili
Functional connectivity in human brain can be represented as a network using electroencephalography (EEG) signals. Network representation of EEG time series can be an efficient vehicle to understand the underlying mechanisms of brain function. Brain functional networks whose nodes are brain regions and edges correspond to functional links between them are characterized by neurobiologically meaningful graph theory metrics. This study investigates the degree to which graph theory metrics are sex dependent. To this end, EEGs from 24 healthy female subjects and 21 healthy male subjects were recorded in eyes-closed resting state conditions. The connectivity matrices were extracted using correlation analysis and were further binarized to obtain binary functional networks. Global and local efficiency measures as graph theory metrics were computed for the extracted networks. We found that male brains have significantly greater global efficiency (i.e., global communicability of the network) across all frequency bands for a wide range of cost values in both hemispheres. Furthermore, for a range of cost values, female brains showed significantly greater right-hemispheric local efficiency (i.e., local connectivity) than male brains.
人脑的功能连接可以用脑电图信号表示为一个网络。脑电图时间序列的网络表示是理解脑功能潜在机制的有效工具。脑功能网络的节点是脑区域,边缘对应于脑区域之间的功能连接,用神经生物学上有意义的图论度量来表征。本研究调查了图论度量是性别依赖的程度。为此,我们记录了24名健康女性受试者和21名健康男性受试者在闭眼静息状态下的脑电图。通过关联分析提取连通性矩阵,进一步二值化得到二值泛函网络。作为图论度量,计算了提取的网络的全局和局部效率度量。我们发现,男性大脑在两个半球的各种成本值下,在所有频带上都具有显著更高的全球效率(即网络的全球通信能力)。此外,在成本值范围内,女性大脑的右半球局部效率(即局部连通性)明显高于男性大脑。
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引用次数: 6
Effect of anisotropies on the magnetization dynamics 各向异性对磁化动力学的影响
IF 1 4区 数学 Q2 Mathematics Pub Date : 2015-02-01 DOI: 10.3934/NHM.2015.10.209
L. Pérez, J. Bragard, H. Mancini, J. Gallas, A. M. Cabanas, O. Suarez, D. Laroze
We report a systematic investigation of the magnetic anisotropy effects observed in the deterministic spin dynamics of a magnetic particle in the presence of a time-dependent magnetic field. The system is modeled by the Landau-Lifshitz-Gilbert equation and the magnetic field consists of two terms, a constant term and a term involving a harmonic time modulation. We consider a general quadratic anisotropic energy with three different preferential axes. The dynamical behavior of the system is represented in Lyapunov phase diagrams, and by calculating bifurcation diagrams, Poincare sections and Fourier spectra. We find an intricate distribution of shrimp-shaped regular island embedded in wide chaotic phases. Anisotropy effects are found to play a key role in defining the symmetries of regular and chaotic stability phases.
我们报告了一个系统的研究磁粒子的磁各向异性效应的确定性自旋动力学中观察到的时间相关的磁场存在。该系统由Landau-Lifshitz-Gilbert方程建模,磁场由两个项组成,一个常数项和一个涉及谐波时间调制的项。我们考虑具有三个不同优先轴的一般二次型各向异性能量。系统的动力学行为用李雅普诺夫相图、分岔图、庞加莱截面和傅立叶谱表示。我们发现虾形规则岛的复杂分布嵌在宽混沌相中。发现各向异性效应在定义规则和混沌稳定相的对称性方面起着关键作用。
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引用次数: 10
Open problems and research perspectives for irrigation channels 灌溉渠的开放性问题与研究展望
IF 1 4区 数学 Q2 Mathematics Pub Date : 2009-07-13 DOI: 10.3934/NHM.2009.4.2I
G. Bastin, A. Bayen, C. D'apice, X. Litrico, B. Piccoli
1. Introduction: Management of canal networks at the age of information technology. With the miniaturization of sensors and their decreasing costs, the paradigm of instrumentation of the built infrastructure and the environment has now been underway for several years, leading to numerous successful and sometimes spectacular realizations such as the instrumentation of the Golden Gate with wireless sensors a few years ago. The convergence of communication, control and sensing on numerous platforms including multi-media platforms has enabled engineers to augment physical infrastructure systems with an information layer, capable of realtime monitoring, with particular success in the health monitoring community. This paradigm has reached a level of maturity, revealed by the emergence of numerous technologies usable to monitor the built infrastructure. Supervisory Control And Data Acquisition (SCADA) systems are a perfect example of such infrastructure, which integrate sensing, communication and control. In the context of management of irrigation networks, the impact of this technology on the control of such systems has the potential of significantly improving efficiency of operations. The idea of “closing the loop” in large scale infrastructure systems is not new, in fact in water management systems such as estuarine environments in the US, State authorities have talked about it for now more than a decade, for example in California. In Vietnam, farmers already operate gates on tidal timescales to manage irrigation properly for rice and shrimps. The “last mile” in enabling one to “close the loop” (at least in the case of estuarine environments is the capability of using sensor data in real time to integrate accurate hydrodynamic features of the system which directly intervene in the feedback loop. 2. Contributions. This special issue of Networks and Heterogeneous Media assembles a collection of articles linked with a workshop on“Irrigation channels and related problems” organized in Maiori, Italy, October 2-4, 2008. The workshop involved experts with fields which included sensor hardware manufacturing, estimation and control, hydrodynamic modeling and control and optimization of partial differential equations. The goal of the workshop was to cross-fertilize ideas between these different fields with the irrigation application in mind. This special issue of Networks and Heterogeneous Media includes articles by some of the presenters on their respective topics of expertise. The complete list, in alphabetical order, is the following:
1. 导论:信息技术时代的运河网管理。随着传感器的小型化及其成本的降低,建筑基础设施和环境的仪器仪表模式已经进行了几年,导致了许多成功的,有时是壮观的实现,例如几年前的金门无线传感器仪器仪表。通信、控制和传感在包括多媒体平台在内的众多平台上的融合,使工程师能够用信息层增强物理基础设施系统,能够进行实时监测,在健康监测领域取得了特别成功。这种模式已经达到了成熟的程度,这是由许多可用于监视已构建的基础设施的技术的出现所揭示的。监控和数据采集(SCADA)系统是这种基础设施的一个完美例子,它集成了传感、通信和控制。在灌溉网管理方面,这项技术对控制这类系统的影响有可能大大提高作业效率。在大型基础设施系统中“闭环”的想法并不新鲜,事实上,在美国的河口环境等水管理系统中,州当局已经讨论了十多年,例如在加利福尼亚州。在越南,农民已经在潮汐时间尺度上操作闸门,以适当地管理水稻和虾的灌溉。实现“闭环”的“最后一英里”(至少在河口环境的情况下)是实时使用传感器数据来整合直接干预反馈回路的系统的精确水动力特征的能力。2. 的贡献。这期《网络与异质媒体》特刊汇集了与2008年10月2日至4日在意大利Maiori举办的“灌溉渠道及相关问题”研讨会相关的文章。研讨会的专家包括传感器硬件制造、估计和控制、流体动力学建模和控制以及偏微分方程优化等领域的专家。研讨会的目标是在考虑灌溉应用的情况下,在这些不同领域之间进行交叉施肥。本期《网络与异质媒体》特刊包括一些演讲者关于他们各自专业领域的文章。完整的名单按字母顺序排列如下:
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引用次数: 13
Special issue from the launching meeting ofnetworks and heterogeneous media 来自网络和异构媒体启动会议的特刊
IF 1 4区 数学 Q2 Mathematics Pub Date : 2006-10-01 DOI: 10.3934/NHM.2006.1.4I
B. Piccoli
The launching meeting of Networks and Heterogeneous Media took place on June 21-23 2006 in Maiori (Salerno, Italy). The meeting was sponsored by the American Institute of Mathematical Sciences, the Istituto per le Applicazioni del Calcolo of Roma, and the DIIMA of University of Salerno. For more information please click the "Full Text" above.
网络与异质媒体启动会议于2006年6月21日至23日在意大利萨莱诺市的Maiori举行。这次会议是由美国数学科学研究所、罗马Calcolo应用研究所和萨莱诺大学DIIMA主办的。欲了解更多信息,请点击上面的“全文”。
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引用次数: 0
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