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Kaplan-Meier and Cox proportional hazards regression in survival analysis: statistical standard and guideline of Life Cycle Committee Kaplan-Meier和Cox比例风险回归在生存分析中的应用:生命周期委员会统计标准和指南
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-17 DOI: 10.54724/lc.2023.e8
S. Lee
In medical research, analyzing the time it takes for a phenomenon to occur is sometimes crucial. However, various factors can contribute to the length of survival or observation periods, and removing specific data can lead to bias results. In this paper, we discuss the Kaplan-Meier analysis and Cox proportional hazards regression model, which are the most frequently used methods in survival analysis. For the first step, we shall discuss the temporal concepts needed in survival analysis, such as cohort studies and then the basic statistical functions dealt with in survival analysis. After solidifying the concepts, methods of understanding and practical application of the Kaplan-Meier survival analysis is noted. After that, we will discuss the analysis methods for the Cox proportional hazards regression model, which includes multiple covariates. With the interpretation method of Cox proportional hazards regression result, we then discuss methods for checking the assumptions of the Cox proportional hazards regression, such as log minus log plots. Finally, we briefly explain the concept of time-dependent regression analysis. It is our aim that through this paper, readers can obtain an understanding on survival analysis and learn how to perform it.
在医学研究中,分析现象发生所需的时间有时是至关重要的。然而,各种因素可能影响生存期或观察期的长度,删除特定数据可能导致偏倚结果。本文讨论了生存分析中最常用的Kaplan-Meier分析和Cox比例风险回归模型。第一步,我们将讨论生存分析中需要的时间概念,例如队列研究,然后是生存分析中处理的基本统计函数。在巩固了概念之后,指出了Kaplan-Meier生存分析的理解方法和实际应用。之后,我们将讨论包含多个协变量的Cox比例风险回归模型的分析方法。结合Cox比例风险回归结果的解释方法,讨论了检验Cox比例风险回归假设的方法,如对数-对数图。最后,我们简要解释了时间相关回归分析的概念。我们的目的是通过本文,让读者了解生存分析,并学习如何进行生存分析。
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引用次数: 7
Sustainable diets optimal design for the massive food services: economic versus environmental aspects 可持续饮食大规模食品服务的最佳设计:经济与环境方面
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-16 DOI: 10.1007/s11367-023-02163-z
Javiera García-Leal, Andrea Teresa Espinoza Pérez, Óscar C. Vásquez
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引用次数: 1
What are the main environmental impacts and products contributing to the biodiversity footprint of EU consumption? A comparison of life cycle impact assessment methods and models 欧盟消费的生物多样性足迹的主要环境影响和产品是什么?生命周期影响评价方法和模型的比较
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-15 DOI: 10.1007/s11367-023-02169-7
E. Sanyé‐Mengual, F. Biganzoli, A. Valente, S. Pfister, Serenella Sala
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引用次数: 2
Factors contributing to the relevance and continuity of life cycle assessment networks 促进生命周期评估网络的相关性和连续性的因素
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-15 DOI: 10.1007/s11367-023-02180-y
Johanna Suikkanen, Susanna Horn, Jáchym Judl, D. Lazarevic, J. Niemistö
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引用次数: 0
Shifts in COVID-19 vaccine acceptance rates among African countries: A systematic review and meta-analysis 非洲国家COVID-19疫苗接受率的变化:系统回顾和荟萃分析
3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-10 DOI: 10.54724/lc.2023.e7
Yejoon Kim, Wongi Woo, Vincent Kipkorir, Masoud Rahmati, Ai Koyanagi, Jae Il Shin, Lee Smith
Objective: The few existing country-specific studies on vaccine hesitancy in Africa are limited by their focus on specific population groups such as health care workers or medical students. Thus, we aimed to provide a comparative systematic review and meta-analysis of COVID-19 vaccine acceptance rates in African countries and their predictors. Methods: Fifteen studies on COVID-19 vaccine acceptance rates in African countries were reviewed in the PubMed/MEDLINE, Embase, and Google Scholar. Meta-analysis investigated the summary effect and inter-study heterogeneity of vaccine acceptance rates and influential factors. Results: Overall, the COVID-19 vaccine acceptance rate was 71.0% (95% CI 64.0 to 77.0). However, as time passed, the vaccine acceptance rate showed a decrease (second half of 2020: 81%, first half of 2021: 67%). Also, the vaccine acceptance rates in urban areas were higher than in rural areas (urban: 82%, rural: 72%). When considering region, vaccine acceptance rates in Eastern and Southern African countries were higher than in Western and North African countries (East: 72%, South: 72%, West: 60%, and North: 52%). Finally, factors such as older age, male sex, and wealth were identified as factors associated with a more acceptive attitude toward vaccination. Conclusion: COVID-19 vaccine acceptance rates demonstrated shifts and was affected by several factors. The rates decreased over time, were lower in rural (vs. urban) settings, and were relatively low in Northern and West African countries (vs. Southern and East African countries). We also found differences in vaccine acceptance rates by some socio-demographic characteristics. Targeting these characteristics, devising strategies to improve vaccine uptake in Africa could help improve vaccination rates.
目的:目前针对非洲疫苗犹豫的国别研究为数不多,但由于其重点关注特定人群,如卫生保健工作者或医学生,因此受到限制。因此,我们旨在对非洲国家的COVID-19疫苗接受率及其预测因素进行比较系统回顾和荟萃分析。方法:在PubMed/MEDLINE、Embase和Google Scholar中对15项非洲国家COVID-19疫苗接受率的研究进行综述。meta分析调查了疫苗接受率和影响因素的总体效应和研究间异质性。结果:总体而言,COVID-19疫苗合格率为71.0% (95% CI为64.0 ~ 77.0)。但随着时间的推移,疫苗接种率呈下降趋势(2020年下半年:81%,2021年上半年:67%)。此外,城市地区的疫苗接种率高于农村地区(城市:82%,农村:72%)。在考虑区域时,东部和南部非洲国家的疫苗接受率高于西部和北非国家(东部:72%,南部:72%,西部:60%,北部:52%)。最后,年龄较大、男性和财富等因素被确定为对疫苗接种更接受态度的相关因素。结论:新冠肺炎疫苗接种率存在变化,受多种因素影响。随着时间的推移,发病率下降,农村(与城市相比)发病率较低,北非和西非国家(与南部和东非国家相比)发病率相对较低。我们还发现一些社会人口统计学特征在疫苗接受率方面存在差异。针对这些特点,制定战略以提高非洲的疫苗接种率,可能有助于提高疫苗接种率。
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引用次数: 0
Shifts in COVID-19 vaccine acceptance rates among African countries: A systematic review and meta-analysis 非洲国家COVID-19疫苗接受率的变化:系统回顾和荟萃分析
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-10 DOI: 10.21203/rs.3.rs-1998674/v1
Yejoo Kim, W. Woo, V. Kipkorir, M. Rahmati, A. Koyanagi, J. Shin, Lee Smith
Objective: To provide a comparative systematic review and meta-analysis of COVID-19 vaccine acceptance rates in African countries and their predictors. Methods: : Fifteen studies on COVID-19 vaccine acceptance rate s in African countries were reviewed in the Medline database via PubMed. Meta-analysis investigated the summary effect and inter-study heterogeneity of vaccine acceptance rates and influential factors. Results: : Overall, the COVID-19 vaccine acceptance rate was 71% (95% CI 64-77). As time passed, the vaccine acceptance rate decreased (second half of 2020: 81%, first half of 2021: 67%). Also, the vaccine acceptance rates in urban areas were higher than in rural areas (urban: 82%, rural: 72%). When considering region, vaccine acceptance rates in Eastern and Southern African countries were higher than in Western and North African countries (East: 72%, South: 72%, West: 60%, North: 52%). Finally, factors such as older age, male sex, and wealth were identified as factors associated with a more acceptive attitude toward vaccination. Conclusions: : COVID-19 vaccine acceptance rates demonstrated shifts and was affected by several factors. The rates decreased over time, were lower in rural (vs. urban) settings, and were relatively low in Northern and West African countries (vs. Southern and East African countries). We also found differences in vaccine acceptance rates by some socio-demographic characteristics. Targeting these characteristics, devising strategies to improve vaccine uptake in Africa could help improve vaccination rates.
目的:对非洲国家COVID-19疫苗接受率及其预测因素进行比较系统回顾和荟萃分析。方法:通过PubMed对Medline数据库中15项非洲国家COVID-19疫苗接受率的研究进行综述。meta分析调查了疫苗接受率和影响因素的总体效应和研究间异质性。结果:总体而言,COVID-19疫苗合格率为71% (95% CI 64-77)。随着时间的推移,疫苗接种率下降(2020年下半年:81%,2021年上半年:67%)。此外,城市地区的疫苗接种率高于农村地区(城市:82%,农村:72%)。在考虑区域时,东部和南部非洲国家的疫苗接受率高于西部和北非国家(东部:72%,南部:72%,西部:60%,北部:52%)。最后,年龄较大、男性和财富等因素被确定为对疫苗接种更接受态度的相关因素。结论:COVID-19疫苗接种率存在变化,并受多种因素影响。随着时间的推移,发病率下降,农村(与城市相比)发病率较低,北非和西非国家(与南部和东非国家相比)发病率相对较低。我们还发现一些社会人口统计学特征在疫苗接受率方面存在差异。针对这些特点,制定战略以提高非洲的疫苗接种率,可能有助于提高疫苗接种率。
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引用次数: 1
Process simulation-based life cycle assessment of the six-step Cu-Cl Cycle of green hydrogen generation and comparative analysis with other Cu-Cl cycles 基于过程模拟的绿色制氢六步Cu-Cl循环生命周期评估及与其他Cu-Cl周期的比较分析
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-09 DOI: 10.1007/s11367-023-02156-y
Poonam Sutar, Ramdas S. Kadam, G. Yadav
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引用次数: 3
Life cycle assessment of bio-based fertilizers production systems: where are we and where should we be heading? 生物基肥料生产系统的生命周期评估:我们在哪里,我们应该向哪里发展?
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-03 DOI: 10.1007/s11367-023-02168-8
D. Egas, S. Azarkamand, C. Casals, S. Ponsá, L. Llenas, J. Colón
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引用次数: 1
Contribution of the Product Social Impact Life Cycle Assessment (PSILCA) database in assessing the risks and opportunities of a jar of honey production 产品社会影响生命周期评估(PSILCA)数据库在评估一罐蜂蜜生产的风险和机会方面的贡献
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-02 DOI: 10.1007/s11367-023-02171-z
Bianca Maria Tragnone, Ioannis Arzoumanidis, Manuela D’Eusanio, L. Petti
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引用次数: 2
Alignment of the life cycle initiative’s “principles for the application of life cycle sustainability assessment” with the LCSA practice: A case study review 生命周期倡议的“生命周期可持续性评估应用原则”与LCSA实践的一致性:案例研究综述
IF 4.8 3区 环境科学与生态学 Q2 ENGINEERING, ENVIRONMENTAL Pub Date : 2023-05-02 DOI: 10.1007/s11367-023-02162-0
Noémie Leroy-Parmentier, S. Valdivia, P. Loubet, G. Sonnemann
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引用次数: 0
期刊
International Journal of Life Cycle Assessment
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