Skull base surgery is a highly specialized interdisciplinary field, the importance of which has grown significantly in recent decades. It requires a high level of technical equipment, specialized personnel, and interdisciplinary cooperation, and, due to its complexity, it can often only be performed adequately at university hospitals or high-volume centers. The ability to perform skull base surgery requires many years of complex surgical training. Certified interdisciplinary skull base centers are being developed nationally and internationally to provide patients with the highest level of care. The aim of this review is to give an overview of the current situation based on the most common clinical challenges in order to discuss the common typical "unmet clinical needs" and the future perspectives of skull base surgery.
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