Heart & Lung最新文献_第8页

A cross-sectional study of Hispanic and Latina/o/x/e individuals’ acute coronary syndrome symptom knowledge, attitudes, and beliefs 一项关于西班牙裔和拉丁裔/女性/男性/女性急性冠状动脉综合征症状知识、态度和信念的横断面研究。

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-13 DOI: 10.1016/j.hrtlng.2024.05.007

John R. Blakeman PhD, RN, PCCN , Susana J. Calderon PhD, RN , Susie Watkins PhD, RN, CNE, CPAHA , MyoungJin Kim PhD , Kate Peterson MSN, RN, CPN, CNE , Marilyn A. Prasun PhD, CCNS, CNL, CHFN, FAHA

Background

Little attention has been placed on language proficiency as a potential variable affecting ACS symptom knowledge, attitudes, and beliefs.

Objectives

To compare the ACS symptom knowledge, attitudes, and beliefs of Hispanic and Latina/o/x/e individuals proficient in English and in those only proficient in Spanish. Secondary aims were to determine if there were differences in ACS symptom knowledge, attitudes, or beliefs based on participants’ previous exposure to ACS symptom information and to evaluate instrument characteristics of the new Spanish version of the ACS Response Index.

Methods

This cross-sectional, comparative study included participants (N = 99) from a community-based clinic in Illinois. Knowledge, attitudes, and beliefs related to ACS symptoms were measured using the ACS Response Index.

Results

The average participant was 39.8 (SD 15.6) years of age, female (n = 56, 56.6 %), and had a high school education or less (n = 61, 61.6 %). Participants correctly classified a mean 57.5 % (SD 12.8) of symptoms and had mean attitude and belief scores of 12.1 (SD 3.3) and 17.5 (SD 2.9), respectively. There were no significant differences in knowledge, attitudes, and beliefs based on language proficiency. However, there were some statistically significant differences for knowledge and attitude scores based on exposure to ACS symptom information. The ACS Response Index (Spanish Version) also demonstrated favorable internal consistency.

Conclusions

Overall knowledge, attitude, and belief scores were modest in this sample. Higher knowledge and attitude scores were observed for some types of ACS information exposure, supporting the importance of future educational efforts in this population.

背景：语言能力是影响 ACS 症状知识、态度和信念的一个潜在变量，但人们对语言能力的关注却很少：目的：比较精通英语的西班牙裔和拉丁裔/o/x/e 人与仅精通西班牙语的西班牙裔和拉丁裔/o/x/e 人对 ACS 症状的了解、态度和信念。次要目的是根据参与者以前接触 ACS 症状信息的情况，确定他们在 ACS 症状知识、态度或信念方面是否存在差异，并评估新版西班牙语 ACS 反应指数的工具特性：这项横断面比较研究的参与者（N = 99）来自伊利诺伊州的一家社区诊所。使用 ACS 反应指数测量了与 ACS 症状相关的知识、态度和信念：参与者平均年龄为 39.8 岁（SD 15.6），女性（n = 56，56.6%），高中或以下学历（n = 61，61.6%）。参与者对症状的正确分类率平均为 57.5%（标准差 12.8），态度和信念的平均得分分别为 12.1 分（标准差 3.3 分）和 17.5 分（标准差 2.9 分）。在知识、态度和信念方面，语言能力没有明显差异。然而，根据接触 ACS 症状信息的情况，知识和态度得分存在一定的统计学差异。ACS 反应指数（西班牙语版）也显示出良好的内部一致性：该样本的总体知识、态度和信念得分不高。在接触某些类型的 ACS 信息时，可观察到较高的知识和态度得分，这证明了未来在这一人群中开展教育工作的重要性。

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引用次数: 0

American Association of Heart failure nurses’ knowledge, barriers and facilitators in conducting research 美国心力衰竭护士协会对开展研究的认识、障碍和促进因素

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-11 DOI: 10.1016/j.hrtlng.2024.04.006

Cheryl Westlake PhD, RN, ACNS-BC, FHFSA, FAHA, FAAN, Director of Nursing Research and EBP, Professor Emerita , Kristen A. Sethares PhD, RN, CNE, FAHA, FHFSA, Professor of Nursing , Aimee Hamel MSN, RN, PhD Student

Background

To provide high-quality patient care, heart failure (HF) nurses must comprehend/use best evidence; however, HF nurses’ ability to do so are unknown.

Objectives

To describe HF nurses’ research interest/involvement, confidence, facilitators/motivators, and barriers to lead/collaborate in research studies.

Methods

A descriptive design with convenience sampling and online data collection (Qualtrics) were used with American Association of HF Nurses members. Recruited/included nurses (n = 145) needed to be of any educational level and currently practicing in any practice setting in the United States. A 30-item, adapted instrument assessed research interest (one-question), involvement (two-questions), confidence (two-questions), facilitators (one-question), motivators (three-questions), and barriers (21-questions).

Results

Subjects (n = 145) were Caucasian (n = 124, 86.1 %) females (n = 137, 96.5 %) with an average age of 52.5 ± 10.38 years and 26.90±12.06 years of nursing experience. Nurses were interested in conducting nursing research (7.78/10±2.37) but involvement was low. Most frequently (n = 73, 50.3 %) nurses served as principal/co-investigators. Confidence with research participation was moderate (70.28/100±26.92) and in their ability to understand/apply research findings were low (21.68/100±80.07). The most frequently reported facilitator was the ability to control their own schedule/work (n = 30, 20.7 %) and the strongest motivator (n = 107, 73.8 %) was the perception presenting nursing research/EBP impacts HF care. The greatest reported barrier was the authority to seek research funding (2.39/5 ± 1.14). Nursing experience (p=.034), interest in participating in nursing research (p=.01), and how much presenting nursing research/EBP impacted one's performance review (p<.001) added to the prediction (R²=0.499, p<.001).

Conclusions

The gained knowledge may promote development of innovative programs and educational opportunities to increase HF nurses’ research activities.

背景为了提供高质量的患者护理，心力衰竭（HF）护士必须理解/使用最佳证据；然而，HF 护士是否有能力做到这一点却不得而知。被招募/纳入的护士（n = 145）需要具有任何教育水平，目前在美国任何实践环境中执业。结果受试者（n = 145）为白种人（n = 124，86.1%），女性（n = 137，96.5%），平均年龄（52.5±10.38）岁，护理经验（26.90±12.06）年。护士对开展护理研究感兴趣（7.78/10±2.37），但参与度较低。大多数情况下（n = 73，50.3%）护士担任主要/共同研究者。对参与研究的信心一般（70.28/100±26.92），对理解/应用研究结果的能力较低（21.68/100±80.07）。最常报告的促进因素是能够控制自己的时间安排/工作（n = 30，20.7%），最强的激励因素（n = 107，73.8%）是认为护理研究/EBP 会影响高频护理。据报告，最大的障碍是寻求研究资金的权力（2.39/5 ± 1.14）。护理经验（p=.034）、参与护理研究的兴趣（p=.01）以及发表护理研究/EBP对个人绩效考核的影响程度（p<.001）增加了预测结果（R2=0.499，p<.001）。

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引用次数: 0

Board of Directors 董事会

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-11 DOI: 10.1016/S0147-9563(24)00072-4

引用次数: 0

Association between red blood cell distribution width and the all-cause mortality of patients with aortic stenosis: A retrospective study 主动脉瓣狭窄患者的红细胞分布宽度与全因死亡率之间的关系：一项回顾性研究

IF 2.4 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Heart & Lung

Pub Date : 2024-05-11 DOI: 10.1016/j.hrtlng.2024.04.020

Benhui Liang , Yiyang Tang , Shien Li , Xinyi Zhou , Mukamengjiang Juaiti , Lihuang Zha , Zaixin Yu , Meijuan Wang , Yilu Feng

Background

It is essential to assess the risk stratification of patients with aortic stenosis (AS).

Objective

To clarify the predictive value of red blood cell distribution width (RDW) in AS patients using a large cohort from the MIMIC-IV database.

Methods

Restricted cubic spline, the Kaplan-Meier method, and logistic and Cox regression analyses were used to explore the association between RDW and all-cause mortality in AS patients. Multivariate adjustments, propensity score matching and weighting, and subgroup analysis were conducted to exclude confounding factors. Receiver operating characteristic (ROC) and decision curve analysis (DCA) curves were drawn to evaluate the predictive performance of RDW.

Results

1,148 patients with AS were included. Their death risks gradually increased with the elevation of RDW. Multivariate-adjusted 90-day (OR: 2.12; HR: 1.90; p = 0.001) and 1-year (OR: 2.07; HR: 1.97; p < 0.001) all-cause mortalities were significantly higher in patients with RDW≥14.7 %, which remained robust after propensity score matching and subgroup analysis. For AS patients with high RDW, those < 75 years old had higher death risks than those ≥ 75 years old. The area under the ROC curve of RDW were 0.741 and 0.75 at 90-day and 1-year follow-ups, respectively, exhibiting comparable performance to acute physiology score III and outperforming other critical illness scores in predicting the prognosis of AS patients. DCA curves also illustrated that RDW had a wide range of net benefits.

Conclusions

High RDW was independently associated with increased 90-day and 1-year all-cause mortalities of AS patients, with strong predictive capability of prognosis.

背景：评估主动脉瓣狭窄（AS）患者的风险分层至关重要：评估主动脉瓣狭窄（AS）患者的风险分层至关重要：利用 MIMIC-IV 数据库中的大型队列，明确红细胞分布宽度（RDW）对 AS 患者的预测价值：方法：采用限制立方样条法、Kaplan-Meier法、逻辑回归分析和Cox回归分析来探讨RDW与强直性脊柱炎患者全因死亡率之间的关系。为排除混杂因素，进行了多变量调整、倾向评分匹配和加权以及亚组分析。绘制了接收者操作特征（ROC）和决策曲线分析（DCA）曲线，以评估RDW的预测性能：结果：共纳入 1,148 例 AS 患者。他们的死亡风险随着RDW的升高而逐渐增加。多变量调整后的 90 天（OR：2.12；HR：1.90；p = 0.001）和 1 年（OR：2.07；HR：1.97；p < 0.001）全因死亡率在 RDW≥14.7% 的患者中明显更高，经过倾向得分匹配和亚组分析后，这一结果仍然很可靠。对于RDW较高的强直性脊柱炎患者，年龄小于75岁的患者的死亡风险高于年龄≥75岁的患者。在90天和1年随访中，RDW的ROC曲线下面积分别为0.741和0.75，在预测强直性脊柱炎患者的预后方面表现与急性生理学评分III相当，优于其他危重症评分。DCA曲线还表明，RDW具有广泛的净效益：结论：高RDW与强直性脊柱炎患者90天和1年全因死亡率增加有独立关联，对预后有很强的预测能力。

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引用次数: 0

The impact of time from ILD diagnosis to referral to the transplant center on the probability of inclusion in the transplant waiting list 从 ILD 诊断到转诊至移植中心的时间对纳入移植候选名单概率的影响

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-11 DOI: 10.1016/j.hrtlng.2024.04.022

Víctor M. Mora-Cuesta PhD , Amaya Martínez-Meñaca MD , Ángel González-Fernández MD , David Iturbe-Fernández MD , Sandra Tello-Mena MD , Sheila Izquierdo-Cuervo MD , Sonia Fernández-Rozas MD , Pilar Alonso-Lecue PhD , José M Cifrián-Martínez PhD

Background

Lung transplant is a therapeutic option for patients with progressive interstitial lung disease (ILD).

Objectives

The objective of this study was to determine whether time from ILD diagnosis to referral to a transplant center influences the probability of being included in the transplant waiting list.

Methods

We performed a retrospective cohort study including all ILD patients evaluated as lung transplantation (LT) candidates at a lung transplant center between 01/01/2017 and 31/12/2022. The primary endpoint was the probability of being included in the lung transplant waiting list according to the time elapsed from diagnosis to referral to the transplant center.

Results

A total of 843 lung transplant requests were received, of which 367 (43.5%) were associated with ILD. Thirteen patients were excluded because they did not attend the first visit, whereas another 11 were excluded because some information was missing. As a result, our final sample was composed of 343 patients. The median time from diagnosis to referral was 29.4 (10.9 – 61.1) months. The overall probability of inclusion in the waiting list was 29.7%. By time from diagnosis to referral, the probability of inclusion in the waiting list was 48.1% for the patients referred 〈 6 months from diagnosis; 27.5% for patients referred 6 to 24 months from diagnosis; and 25.8% for patients referred 〉 24 months from diagnosis (p = 0.007).

Conclusions

Early referral to a lung transplant center seemed to increase the probability of being included in the lung transplant waiting list. Further research is needed in this topic.

背景肺移植是进展性间质性肺疾病（ILD）患者的一种治疗选择.目的本研究旨在确定从 ILD 诊断到转诊至移植中心的时间是否会影响被纳入移植候选名单的概率.方法我们进行了一项回顾性队列研究，研究对象包括 2017 年 1 月 1 日至 2022 年 12 月 31 日期间在肺移植中心被评估为肺移植（LT）候选者的所有 ILD 患者。主要终点是根据从诊断到转诊到移植中心的时间被纳入肺移植候选名单的概率。结果共收到 843 份肺移植申请，其中 367 份（43.5%）与 ILD 相关。13名患者因未参加首次就诊而被排除，另有11名患者因缺少某些信息而被排除。因此，我们的最终样本由 343 名患者组成。从诊断到转诊的中位时间为 29.4（10.9 - 61.1）个月。纳入候诊名单的总体概率为 29.7%。从确诊到转诊的时间来看，确诊后〈 6 个月转诊的患者被纳入候选名单的概率为 48.1%；确诊后 6 至 24 个月转诊的患者被纳入候选名单的概率为 27.5%；确诊后〉 24 个月转诊的患者被纳入候选名单的概率为 25.8%（P = 0.007）。本课题需要进一步研究。

{"title":"The impact of time from ILD diagnosis to referral to the transplant center on the probability of inclusion in the transplant waiting list","authors":"Víctor M. Mora-Cuesta PhD , Amaya Martínez-Meñaca MD , Ángel González-Fernández MD , David Iturbe-Fernández MD , Sandra Tello-Mena MD , Sheila Izquierdo-Cuervo MD , Sonia Fernández-Rozas MD , Pilar Alonso-Lecue PhD , José M Cifrián-Martínez PhD","doi":"10.1016/j.hrtlng.2024.04.022","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.04.022","url":null,"abstract":"<div><h3>Background</h3><p>Lung transplant is a therapeutic option for patients with progressive interstitial lung disease (ILD).</p></div><div><h3>Objectives</h3><p>The objective of this study was to determine whether time from ILD diagnosis to referral to a transplant center influences the probability of being included in the transplant waiting list.</p></div><div><h3>Methods</h3><p>We performed a retrospective cohort study including all ILD patients evaluated as lung transplantation (LT) candidates at a lung transplant center between 01/01/2017 and 31/12/2022. The primary endpoint was the probability of being included in the lung transplant waiting list according to the time elapsed from diagnosis to referral to the transplant center.</p></div><div><h3>Results</h3><p>A total of 843 lung transplant requests were received, of which 367 (43.5%) were associated with ILD. Thirteen patients were excluded because they did not attend the first visit, whereas another 11 were excluded because some information was missing. As a result, our final sample was composed of 343 patients. The median time from diagnosis to referral was 29.4 (10.9 – 61.1) months. The overall probability of inclusion in the waiting list was 29.7%. By time from diagnosis to referral, the probability of inclusion in the waiting list was 48.1% for the patients referred 〈 6 months from diagnosis; 27.5% for patients referred 6 to 24 months from diagnosis; and 25.8% for patients referred 〉 24 months from diagnosis (<em>p</em> = 0.007).</p></div><div><h3>Conclusions</h3><p>Early referral to a lung transplant center seemed to increase the probability of being included in the lung transplant waiting list. Further research is needed in this topic.</p></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140910106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Invited commentary: Association between Red Blood Cell Distribution width and the all-cause mortality of patients with aortic stenosis: A retrospective study 特邀评论：红细胞分布宽度与主动脉瓣狭窄患者全因死亡率的关系：一项回顾性研究

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-08 DOI: 10.1016/j.hrtlng.2024.04.021

Luis D. Berrizbeitia MD

引用次数: 0

Causal role of circulating inflammatory cytokines in cardiac diseases, structure and function 循环炎症细胞因子在心脏疾病、结构和功能中的致病作用

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-07 DOI: 10.1016/j.hrtlng.2024.04.018

Weiqiang Ruan MD , Xiaoqin Zhou MD , Huizhen Liu MS , Ting Wang MS , Guiying Zhang MS , Ke Lin MD

Background

Inflammation is implicated in cardiovascular disease (CVD) pathogenesis, but causal roles of specific circulating inflammatory cytokines remain unclear. Mendelian randomization (MR) studies are well-poised to provide etiological insights beyond constraints of conventional research.

Methods

We conducted a large-scale MR study to investigate potential causal relationships of 91 inflammatory proteins with CVD outcomes and cardiac remodeling using summary-level genetic data. Outcomes included coronary artery disease, myocardial infarction, stroke, atrial fibrillation, heart failure, abdominal aortic aneurysm, deep vein thrombosis of lower extremities, pulmonary embolism, cardiac structure and functional parameters. Inverse-variance weighted analysis was undertaken as the primary analysis, with several sensitivity analyses applied.

Results

Hepatocyte growth factor (HGF) demonstrated a causal relationship with increased susceptibility to both any stroke (OR 1.111; 95 % CI 1.044 - 1.183; P = 9.50e-04) and ischemic stroke (OR 1.121; 95 % CI 1.047 - 1.200; P = 1.04e-03). Programmed cell death 1 ligand 1 (PD-L1) was negatively associated with atrial fibrillation risk (OR 0.936, 95 % CI 0.901 - 0.973; P = 7.69e-04). CCL20, CDCP1, Flt3L and IL-10RA were identified as causal coronary artery disease risk factors, while LIF and ST1A1 had protective effects. IL-4 and LIF-R demonstrated causal links with right heart functional changes.

Conclusions

Our MR study nominates specific circulating inflammatory cytokines as potential targets for CVD treatment and prevention. Further research into mechanisms and clinical translation are warranted.

背景炎症与心血管疾病（CVD）的发病机制有关，但特定循环炎性细胞因子的因果作用仍不清楚。方法我们开展了一项大规模的孟德尔随机化研究，利用汇总级遗传数据调查 91 种炎症蛋白与心血管疾病结局和心脏重塑的潜在因果关系。结果包括冠心病、心肌梗塞、中风、心房颤动、心力衰竭、腹主动脉瘤、下肢深静脉血栓、肺栓塞、心脏结构和功能参数。结果肝细胞生长因子（HGF）与任何中风（OR 1.111; 95 % CI 1.044 - 1.183; P = 9.50e-04）和缺血性中风（OR 1.121; 95 % CI 1.047 - 1.200; P = 1.04e-03）的易感性增加有因果关系。程序性细胞死亡 1 配体 1 (PD-L1) 与心房颤动风险呈负相关（OR 0.936，95 % CI 0.901 - 0.973；P = 7.69e-04）。CCL20、CDCP1、Flt3L和IL-10RA被确定为冠状动脉疾病的致病风险因素，而LIF和ST1A1则具有保护作用。IL-4和LIF-R与右心功能变化有因果关系。结论：我们的磁共振研究发现，特定的循环炎性细胞因子是治疗和预防心血管疾病的潜在靶点。我们的磁共振研究发现，特定的循环炎症细胞因子是治疗和预防心血管疾病的潜在靶点。

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引用次数: 0

Relationship between commonly defined metabolic health phenotypes and obesity with lung function in a working population: A cross-sectional study 工作人群中通常定义的代谢健康表型和肥胖与肺功能之间的关系：横断面研究

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-03 DOI: 10.1016/j.hrtlng.2024.04.017

José-Miguel Guzmán-García PhD , Manuel Romero-Saldaña PhD , Guillermo Molina-Recio PhD , Carlos Álvarez-Fernández PhD , María del Rocío Jiménez-Mérida PhD , Rafael Molina-Luque PhD

Background

Four phenotypes relate metabolism and obesity: metabolically healthy (MHO) and unhealthy (MUO) people with obesity and metabolically healthy (MHNO) and unhealthy (MUNO) people without obesity. No studies have addressed the association between these categories and lung function in the working population.

Objectives

The aim was to determine the relationship of phenotypes to lung ageing as measured by lung age and its relationship to lung dysfunction.

Methods

A descriptive cross-sectional study was conducted in a working population. The outcome variable was lung function assessed by lung age. The four phenotypes of obesity and metabolic health (MHNO, MHO, MUO and MUNO) were determined using NCEP-ATP III criteria. Lung dysfunctions were classified into restrictive, obstructive, and mixed patterns.

Results

The mean age of the participants was 43.7 years, ranging from 18 to 67 years. Of the 1860 workers, 51.3 % were women. The prevalences found were 71.4 %, 12 %, 10.6 % and 6 % for MHNO, MUO, MHO, and MUNO, respectively. MHO (β = 0.66; p = 0.591) was not associated with increased lung ageing compared with MHNO, but MUO (β = 7.1; p < 0.001) and MUNO (β = 6.6; p < 0.001) were. Concerning pulmonary dysfunctions, MUNO (OR = 1.93; p < 0.001) and MUO (OR = 2.91; p < 0.001) were found to be related to the presence of a restrictive pattern, and MUNO (OR = 2.40; p = 0.028) to the mixed pattern.

Conclusion

The results show that metabolic abnormalities, not obesity, are responsible for premature lung ageing and, therefore, lung function decline. In our study, having obesity without metabolic abnormality was not significantly associated with the presence of dysfunctional respiratory patterns.

背景四种表型与代谢和肥胖有关：代谢健康（MHO）和不健康（MUO）的肥胖者，以及代谢健康（MHNO）和不健康（MUNO）的无肥胖者。目前还没有研究涉及这些类别与工作人群肺功能之间的关系。方法在工作人群中进行了一项描述性横断面研究。结果变量是以肺龄评估的肺功能。根据 NCEP-ATP III 标准确定了肥胖和代谢健康的四种表型（MHNO、MHO、MUO 和 MUNO）。结果参与者的平均年龄为 43.7 岁，从 18 岁到 67 岁不等。在 1860 名工人中，51.3% 为女性。MHNO、MUO、MHO 和 MUNO 的患病率分别为 71.4%、12%、10.6% 和 6%。与 MHNO 相比，MHO（β = 0.66；p = 0.591）与肺老化程度增加无关，但 MUO（β = 7.1；p < 0.001）和 MUNO（β = 6.6；p < 0.001）与肺老化程度增加有关。在肺功能障碍方面，MUNO（OR = 1.93；p <；0.001）和 MUO（OR = 2.91；p <；0.001）与限制型模式有关，而 MUNO（OR = 2.40；p = 0.028）与混合型模式有关。在我们的研究中，无代谢异常的肥胖与呼吸模式失调无明显关联。

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引用次数: 0

Association between coffee and caffeine intake and risk of COPD: Findings based on NHANES 2007–2012 咖啡和咖啡因摄入量与慢性阻塞性肺病风险之间的关系：基于 2007-2012 年国家健康调查（NHANES）的研究结果

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-05-02 DOI: 10.1016/j.hrtlng.2024.04.015

Wan-Zhe Liao , Jia-Xin Li , Wei-Yi Feng , Jia-Qi Xiao , Zi-Xun Wang , Shuo-Jia Xie , Yi-Ming Hu , Jun-Hao Mao , Ze-Min Huang , Xu-Guang Guo , Wei-Jie Guan

Background

The association between coffee and caffeine intake and the risk of COPD and lung function has not been thoroughly discussed in Americans, with subgroup and threshold effects remaining unclear.

Objectives

This study investigated the association between coffee and caffeine consumption and the risk of chronic obstructive pulmonary disease (COPD) as well as lung function utilizing data from the NHANES 2007–2012.

Methods

We assessed the associations of coffee and caffeine consumption with the risk of COPD and lung function parameters, including FEV1 and FVC, adjusting for common demographic and disease characteristics in a cross-sectional analysis of NHANES data.

Results

A total of 9763 participants were included in the study, and 592 were diagnosed with COPD. Multivariate regression models revealed positive associations between coffee and caffeine consumption and the risk of COPD and lung function. Subgroup analyses stratified by sex, DM, hypertension status, and smoking habits identified potential effect modifiers as well as inflection points from threshold effect examinations.

Conclusions

The results of this cross-sectional study indicated significant positive correlations between coffee and caffeine consumption and the risk of COPD. Additionally, positive correlations between exposure variables and FEV1 and FVC were detected. Among the stratification factors, smoking status exhibited the most potential for modifying effects. Future practices and research are needed to validate the results and explore the underlying mechanisms

背景美国人对咖啡和咖啡因摄入量与慢性阻塞性肺病（COPD）风险和肺功能之间的关系尚未进行深入探讨，亚组效应和阈值效应尚不明确。方法我们通过对 NHANES 数据进行横断面分析，评估了咖啡和咖啡因的摄入量与慢性阻塞性肺病风险以及肺功能参数（包括 FEV1 和 FVC）之间的关系，并对常见的人口统计学特征和疾病特征进行了调整。多变量回归模型显示，咖啡和咖啡因的摄入量与慢性阻塞性肺病的发病风险和肺功能呈正相关。按性别、糖尿病、高血压状态和吸烟习惯进行的亚组分析确定了潜在的效应调节因子以及阈值效应检查的拐点。结论这项横断面研究的结果表明，咖啡和咖啡因的摄入量与慢性阻塞性肺病的发病风险之间存在显著的正相关。此外，还发现暴露变量与 FEV1 和 FVC 之间存在正相关。在分层因素中，吸烟状况最有可能产生调节作用。未来的实践和研究需要验证这些结果并探索其潜在机制

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引用次数: 0

Personal mastery and quality of life in patients with atrial fibrillation after radiofrequency ablation: The mediating role of health promoting behavior 射频消融术后心房颤动患者的个人掌控能力和生活质量：促进健康行为的中介作用

IF 2.8 4区医学 Q2 Medicine

Heart & Lung

Pub Date : 2024-04-23 DOI: 10.1016/j.hrtlng.2024.04.016

Feng-juan Wang , Chun Zhang , Min-min Cai , Jie-qiong Zhang , Hai-xia Wang

Background

Improving quality of life is vital for patients with atrial fibrillation (AF) after radiofrequency ablation. Quality of life can be affected not only by personal mastery but also by health promoting behavior as previously studied. However, it remains unclear whether health promoting behavior mediates the relationship between personal mastery and quality of life.

Objectives

To explore whether health promoting behavior mediates the relationship between personal mastery and quality of life in patients with AF after radiofrequency ablation.

Methods

A cross-sectional design and convenience sampling were conducted at a tertiary hospital in China. Self-reported questionnaires were used to assess personal mastery, health promoting behavior and quality of life. SPSS and AMOS software were used for statistical analysis.

Results

A total of 202 patients with AF after radiofrequency ablation were enrolled (mean age 58.28 ± 12.70 years). The scores for personal mastery and quality of life were 22.52 ± 2.53 points and 62.58 ± 8.59 points, respectively, indicating a limited level. The health promoting behavior exhibited a moderate level, with scores averaging 103.82 ± 8.47 points. There was a positive correlation between the three variables (all P < 0.05). Health promoting behavior played a partial mediating role in the relationship between personal mastery and quality of life in patients with AF after radiofrequency ablation, accounting for 44.79 % of the total effect.

Conclusions

In order to improve quality of life and prognosis, it is necessary to consider enhancing personal mastery and increasing patient compliance with health promoting behavior, which are important ways to improve their quality of life.

背景提高生活质量对射频消融术后的心房颤动（房颤）患者至关重要。生活质量不仅会受到个人掌握程度的影响，而且还会受到促进健康行为的影响，这一点此前已有研究。目的探讨射频消融术后心房颤动患者的健康促进行为是否会介导个人掌握感与生活质量之间的关系。方法在中国一家三级医院进行横断面设计和便利抽样调查。采用自我报告问卷评估个人主人翁意识、健康促进行为和生活质量。结果共纳入 202 名射频消融术后房颤患者（平均年龄 58.28±12.70 岁）。个人掌握程度和生活质量得分分别为（22.52±2.53）分和（62.58±8.59）分，显示为有限水平。健康促进行为表现出中等水平，平均得分为 103.82 ± 8.47 分。三个变量之间存在正相关（均为 P < 0.05）。健康促进行为在射频消融术后房颤患者的个人掌握与生活质量之间的关系中发挥了部分中介作用，占总效应的 44.79%。结论为了改善生活质量和预后，有必要考虑加强个人掌握和提高患者对健康促进行为的依从性，这是改善生活质量的重要途径。

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