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Enigmatic Medicine: a proposed rebranding of emergency medicine. 谜一般的医学:建议重新命名急诊医学。
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-07-01 DOI: 10.1007/s43678-023-00519-w
Lee Yung Wong
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引用次数: 1
The impact of alternate level of care on access block and operational strategies to reduce emergency wait times: a multi-center simulation study. 备用护理级别对通道阻塞和减少紧急等待时间的操作策略的影响:一项多中心模拟研究
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-07-01 DOI: 10.1007/s43678-023-00514-1
Yuan Tian, Nathaniel D Osgood, James Stempien, Vivian Onaemo, Adrienne Danyliw, Graham Fast, Beliz Acan Osman, Janet Reynolds, Jenny Basran

Objectives: Lengthy emergency department (ED) wait times caused by hospital access block is a growing concern for the Canadian health care system. Our objective was to quantify the impact of alternate-level-of-care on hospital access block and evaluate the likely effects of multiple interventions on ED wait times.

Methods: Discrete-event simulation models were developed to simulate patient flows in EDs and acute care of six Canadian hospitals. The model was populated with administrative data from multiple sources (April 2017-March 2018). We simulated and assessed six different intervention scenarios' impact on three outcome measures: (1) time waiting for physician initial assessment, (2) time waiting for inpatient bed, and (3) patients who leave without being seen. We compared each scenario's outcome measures to the baseline scenario for each ED.

Results: Eliminating 30% of medical inpatients' alternate-level-of-care days reduced the mean time waiting for inpatient bed by 0.25 to 4.22 h. Increasing ED physician coverage reduced the mean time waiting for physician initial assessment (∆ 0.16-0.46 h). High-quality care transitions targeting medical patients lowered the mean time waiting for inpatient bed for all EDs (∆ 0.34-6.85 h). Reducing ED visits for family practice sensitive conditions or improving continuity of care resulted in clinically negligible reductions in wait times and patients who leave without being seen rates.

Conclusions: A moderate reduction in alternate-level-of-care hospital days for medical patients could alleviate access block and reduce ED wait times, although the magnitude of reduction varies by site. Increasing ED physician staffing and aligning physician capacity with inflow demand could also decrease wait time. Operational strategies for reducing ED wait times should prioritize resolving output and throughput factors rather than input factors.

目的:冗长的急诊科(ED)等待时间引起的医院访问阻塞是一个日益关注的加拿大卫生保健系统。我们的目标是量化交替护理级别对医院通道阻塞的影响,并评估多种干预措施对急诊科等待时间的可能影响。方法:建立离散事件模拟模型来模拟加拿大六家医院急诊科和急症护理的病人流动。该模型填充了来自多个来源的管理数据(2017年4月至2018年3月)。我们模拟并评估了六种不同干预方案对三个结果指标的影响:(1)等待医生初步评估的时间,(2)等待住院床位的时间,以及(3)未被看到的患者离开。我们将每个情景的结果测量值与每个ed的基线情景进行了比较。减少30%的医疗住院患者的备选护理级别天数,使平均等待住院床位的时间减少了0.25至4.22小时。增加急诊科医生覆盖率减少了平均等待医生初步评估的时间(∆0.16-0.46小时)。针对医疗患者的高质量护理转变降低了所有急诊科的平均等待住院床位时间(∆0.34-6.85小时)可忽略不计的减少等待时间和病人离开没有看到率。结论:适度减少医疗患者的交替护理级别住院天数可以缓解通道阻塞并减少急诊科等待时间,尽管减少的幅度因地点而异。增加急诊科医生的配备,使医生的能力与流入的需求保持一致,也可以减少等待时间。减少ED等待时间的操作策略应该优先解决输出和吞吐量因素,而不是输入因素。
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引用次数: 2
Just the Facts: Management of return of spontaneous circulation after out-of-hospital cardiac arrest. 事实真相:院外心脏骤停后自然循环恢复的管理。
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-07-01 DOI: 10.1007/s43678-023-00537-8
Hashim Kareemi, Ariel Hendin, Christian Vaillancourt
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引用次数: 0
Qualitative analysis of values and motivation reported by families utilizing a paediatric virtual care emergency clinic launched during the SARS-CoV-2 pandemic. 对利用SARS-CoV-2大流行期间推出的儿科虚拟急诊诊所的家庭报告的价值观和动机进行定性分析。
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s43678-023-00505-2
Victoria Sanderson, Branka Vujcic, Sherry Coulson, Rodrick Lim

Purpose: This is the first study to take an in-depth qualitative approach to identify motivating factors for caregivers who chose the paediatric emergency virtual care option in Canada during the SARS-CoV-2 pandemic. The role that virtual care may play moving forward is also considered.

Methods: Between May 2020 and May 2021, 773 respondents attending the virtual clinic completed a follow-up survey with open-ended questions. For qualitative content analysis, comments were coded and analysed until thematic saturation was reached. Sub-codes were subsumed into major coding categories to identify themes.

Results: Three major themes, including safety, reassurance and convenience, and an overarching theme of satisfaction emerged from this analysis. Paediatric virtual clinic use was motivated in part by a desire to avoid the hospital environment. In-person Emergency Department visits were reported to be challenging and stressful, particularly due to perceived infection risk. Respondents appreciated that the clinic provided reassurance by assisting in navigating the healthcare system during a time of uncertainty and felt the virtual option allowed them to use healthcare resources responsibly. The convenience and ease of access to virtual care allowed for improved family-centred care in vulnerable populations. The overarching theme of satisfaction was emphasized by numerous comments for this service to be offered post-pandemic.

Conclusion: Our study indicates that virtual care was an attractive option for caregivers due to the safety, reassurance, and convenience provided. The strong patient desire for continued availability post-pandemic will be important considerations in this rapidly developing area of care.

目的:这是第一项采用深入定性方法的研究,旨在确定在SARS-CoV-2大流行期间加拿大选择儿科急诊虚拟护理选项的护理人员的激励因素。本文还考虑了虚拟医疗在未来可能发挥的作用。方法:在2020年5月至2021年5月期间,773名参加虚拟诊所的受访者完成了一项带有开放式问题的随访调查。对于定性内容分析,评论被编码和分析,直到主题饱和。子编码被归入主要编码类别,以确定主题。结果:三个主要主题,包括安全,放心和方便,以及满意度的总体主题,从这个分析中出现。儿科使用虚拟诊所的部分动机是希望避免医院环境。据报告,亲自到急诊科就诊具有挑战性和压力,特别是考虑到感染风险。受访者表示,在不确定的时期,诊所通过协助导航医疗保健系统提供了保证,并感到虚拟选项允许他们负责任地使用医疗保健资源。虚拟护理的便利性和便利性使弱势群体能够更好地获得以家庭为中心的护理。关于大流行后提供这项服务的许多评论强调了满意度这一首要主题。结论:我们的研究表明,虚拟护理是一个有吸引力的选择,因为它提供了安全、放心和方便。在这一迅速发展的护理领域,患者对大流行后继续提供服务的强烈愿望将是重要的考虑因素。
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引用次数: 0
An evaluation of satisfaction with emergency department care in children and adolescents with mental health concerns. 有心理健康问题的儿童和青少年对急诊科护理的满意度评价
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s43678-023-00511-4
Conné Lategan, Amanda S Newton, Jennifer Thull-Freedman, Antonia Stang, Eddy Lang, Paul Arnold, Michael Stubbs, Stephen B Freedman

Objectives: We hypothesized that an association exists between satisfaction with ED mental health care delivery and patient and system characteristics. Primary: To evaluate overall satisfaction with ED mental health care delivery. Secondary: To explore aspects of ED mental health care delivery associated with general satisfaction, and patient and ED visit characteristic associated with total satisfaction scores and reported care experience themes.

Methods: We enrolled patients < 18 years of age presenting with a mental health concern between February 1, 2020 and January 31, 2021, to two pediatric EDs in Alberta, Canada. Satisfaction data were collected using the Service Satisfaction Scale, a measure of global satisfaction with mental health services. Association of general satisfaction with ED mental health care was evaluated using Pearson's correlation coefficient and variables associated with total satisfaction score was assessed using multivariable regression analyses. Inductive thematic analysis of qualitative feedback identified satisfaction and patient experience themes.

Results: 646 participants were enrolled. 71.2% were Caucasian and 56.3% female. Median age was 13 years (IQR 11-15). Parents/caregivers (n = 606) and adolescents (n = 40) were most satisfied with confidentiality and respect in the ED and least satisfied with how ED services helped reduce symptoms and/or problems. General satisfaction was associated with perceived amount of help received in the ED (r = 0.85) and total satisfaction with evaluation by a mental health team member (p = 0.004) and psychiatrist consultation (p = 0.05). Comments demonstrated satisfaction with ED provider attitudes and interpersonal skills and dissatisfaction with access to mental health and addictions care, wait time, and the impact of COVID-19.

Conclusions: There is a need to improve ED mental health care delivery, with a focus on timely access to ED mental health providers. Access to outpatient/community-based mental health care is needed to complement care received in the ED and to provide continuity of care for youth with mental health concerns.

目的:我们假设对ED精神卫生保健服务的满意度与患者和系统特征之间存在关联。目的:评价对急诊科精神卫生保健服务的总体满意度。次要目的:探讨ED精神卫生保健提供与总体满意度相关的方面,以及患者和ED就诊特征与总满意度得分和报告的护理体验主题相关的方面。方法:纳入646例患者。71.2%为白种人,56.3%为女性。中位年龄为13岁(IQR 11-15)。父母/照顾者(n = 606)和青少年(n = 40)对急诊科的保密性和尊重最满意,对急诊科服务如何帮助减轻症状和/或问题最不满意。总体满意度与在ED中获得帮助的感知量(r = 0.85)、对心理健康团队成员评估的总满意度(p = 0.004)和精神科医生咨询的总满意度(p = 0.05)相关。评论表明,人们对急诊科医生的态度和人际交往能力感到满意,对获得心理健康和成瘾治疗、等待时间以及COVID-19的影响感到不满。结论:有必要改善急诊科精神卫生服务的提供,重点是及时获得急诊科精神卫生服务提供者。需要获得门诊/社区精神保健,以补充急诊科所接受的护理,并为有精神健康问题的青年提供持续的护理。
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引用次数: 0
Fear, health impacts, and life delays: residents' certification exam year experience. 恐惧,健康影响和生活延迟:居民认证考试年的经验。
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s43678-023-00485-3
Michelle Onlock, Laila Nasser, Tara Riddell, Natasha Snelgrove, Kaif Pardhan

Background: Residency training is associated with risks of burnout and impaired well-being. This may be due to multiple factors, including navigating various transitions. Chief among these is the transition to independent practice which, in Canada, involves a certification exam administered by the Royal College of Physicians and Surgeons of Canada or the College of Family Physicians of Canada. This qualitative study explored the experience of residents in their examination year, including residents impacted by pandemic-related examination postponment, to understand how these experiences may impact residents' well-being.

Methods: Qualitative description methodology was used for this study. Participants were residents and physicians in independent practice from McMaster University and the University of Toronto. In depth, semi-structured, one-on-one interviews were conducted by one of the investigators. Each was transcribed, reviewed, and coded by two members of the investigating team.

Results: Five themes were identified. Examinations were perceived to be a significant stressor, and the extent of preparation involved was viewed as a threat to one's physical and mental well-being. Participants identified a culture of fear surrounding the exam, as well as a perception that exam preparation requires significant sacrifice which can exacerbate the impacts of the exam year. Personal and professional supports were identified as important protective factors.

Conclusion: This study has identified unique challenges in the examination year, and its impact on the well-being of residents immediately before they enter independent practice. Residents also experienced significant learning and a sense of accomplishment through their preparation for the examination. The COVID-19 pandemic had a unique impact on one cohort of residents. This should prompt medical education institutions to examine the support provided to residents, the culture surrounding certification examinations, and mitigation strategies for future examination disruptions.

背景:住院医师培训与职业倦怠和幸福感受损的风险有关。这可能是由于多种因素,包括导航各种转换。其中最主要的是向独立执业的过渡,在加拿大,这涉及到由加拿大皇家内科医生和外科医生学院或加拿大家庭医生学院管理的认证考试。本质性研究探讨居民在考试年度的经历,包括受大流行相关考试推迟影响的居民,以了解这些经历如何影响居民的福祉。方法:本研究采用定性描述方法。参与者是来自麦克马斯特大学和多伦多大学的住院医生和独立执业的医生。其中一名调查人员进行了深入的、半结构化的一对一访谈。每一份报告都由调查小组的两名成员进行转录、审查和编码。结果:确定了五个主题。考试被认为是一个重要的压力源,所涉及的准备程度被视为对一个人的身心健康的威胁。参与者发现了一种围绕考试的恐惧文化,以及一种感觉,即考试准备需要做出重大牺牲,这可能会加剧考试年的影响。个人和专业支持被认为是重要的保护因素。结论:本研究确定了考试年度的独特挑战,以及其对住院医师进入独立执业前幸福感的影响。住院医师也在备考过程中获得了重要的学习和成就感。COVID-19大流行对一群居民产生了独特的影响。这应该促使医学教育机构审视为住院医师提供的支持、围绕认证考试的文化,以及缓解未来考试中断的策略。
{"title":"Fear, health impacts, and life delays: residents' certification exam year experience.","authors":"Michelle Onlock,&nbsp;Laila Nasser,&nbsp;Tara Riddell,&nbsp;Natasha Snelgrove,&nbsp;Kaif Pardhan","doi":"10.1007/s43678-023-00485-3","DOIUrl":"https://doi.org/10.1007/s43678-023-00485-3","url":null,"abstract":"<p><strong>Background: </strong>Residency training is associated with risks of burnout and impaired well-being. This may be due to multiple factors, including navigating various transitions. Chief among these is the transition to independent practice which, in Canada, involves a certification exam administered by the Royal College of Physicians and Surgeons of Canada or the College of Family Physicians of Canada. This qualitative study explored the experience of residents in their examination year, including residents impacted by pandemic-related examination postponment, to understand how these experiences may impact residents' well-being.</p><p><strong>Methods: </strong>Qualitative description methodology was used for this study. Participants were residents and physicians in independent practice from McMaster University and the University of Toronto. In depth, semi-structured, one-on-one interviews were conducted by one of the investigators. Each was transcribed, reviewed, and coded by two members of the investigating team.</p><p><strong>Results: </strong>Five themes were identified. Examinations were perceived to be a significant stressor, and the extent of preparation involved was viewed as a threat to one's physical and mental well-being. Participants identified a culture of fear surrounding the exam, as well as a perception that exam preparation requires significant sacrifice which can exacerbate the impacts of the exam year. Personal and professional supports were identified as important protective factors.</p><p><strong>Conclusion: </strong>This study has identified unique challenges in the examination year, and its impact on the well-being of residents immediately before they enter independent practice. Residents also experienced significant learning and a sense of accomplishment through their preparation for the examination. The COVID-19 pandemic had a unique impact on one cohort of residents. This should prompt medical education institutions to examine the support provided to residents, the culture surrounding certification examinations, and mitigation strategies for future examination disruptions.</p>","PeriodicalId":55286,"journal":{"name":"Canadian Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9626708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do patient outcomes differ when the trauma team leader is a surgeon or non-surgeon? A multicentre cohort study. 当创伤小组组长是外科医生或非外科医生时,病人的治疗结果是否不同?一项多中心队列研究。
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s43678-023-00516-z
John Taylor, Recep Gezer, Vesna Ivkov, Mete Erdogan, Samar Hejazi, Robert Green, John M Tallon, Benjamin Tuyp, Jaimini Thakore, Paul T Engels, Alun Ackery, Andrew Beckett, Kelly Vogt, Neil Parry, Christopher Heyd, Angela Coates, Jacinthe Lampron, Iain MacPhail

Purpose: Trauma team leaders (TTLs) have traditionally been general surgeons; however, some trauma centres use a mixed model of care where both surgeons and non-surgeons (primarily emergency physicians) perform this role. The objective of this multicentre study was to provide a well-powered study to determine if TTL specialty is associated with mortality among major trauma patients.

Methods: Data were collected from provincial trauma registries at six level 1 trauma centres across Canada over a 10-year period. We included adult trauma patients (age ≥ 18 yrs) who triggered the highest-level trauma activation. The primary outcome was the difference in risk-adjusted in-hospital mortality for trauma patients receiving initial care from a surgeon versus a non-surgeon TTL.

Results: Overall, 12,961 major trauma patients were included in the analysis. Initial treatment was provided by a surgeon TTL in 57.8% (n = 7513) of cases, while 42.2% (n = 5448) of patients were treated by a non-surgeon TTL. Unadjusted mortality occurred in 11.6% of patients in the surgeon TTL group and 12.7% of patients in the non-surgeon TTL group (OR 0.87, 95% CI 0.78-0.98, p = 0.02). Risk-adjusted mortality was not significantly different between patients cared for by surgeon and non-surgeon TTLs (OR 0.92, 95% CI 0.80-1.06, p = 0.23). Furthermore, we did not observe differences in risk-adjusted mortality for any of the subgroups evaluated.

Conclusions: After risk adjustment, there was no difference in mortality between trauma patients treated by surgeon or non-surgeon TTLs. Our study supports emergency physicians performing the role of TTL at level 1 trauma centres.

目的:创伤小组组长(TTLs)传统上是普通外科医生;然而,一些创伤中心采用混合护理模式,由外科医生和非外科医生(主要是急诊医生)担任这一角色。这项多中心研究的目的是提供一项强有力的研究,以确定TTL专业是否与重大创伤患者的死亡率相关。方法:从加拿大六个一级创伤中心的省级创伤登记处收集了10年的数据。我们纳入了触发最高水平创伤激活的成人创伤患者(年龄≥18岁)。主要结局是接受外科医生初始治疗的创伤患者与接受非外科医生TTL治疗的创伤患者经风险调整后的住院死亡率的差异。结果:共纳入12961例重大创伤患者。57.8% (n = 7513)的病例由外科医生TTL进行初始治疗,而42.2% (n = 5448)的患者由非外科医生TTL进行治疗。外科医生TTL组11.6%的患者发生未调整死亡率,非外科医生TTL组12.7%的患者发生未调整死亡率(OR 0.87, 95% CI 0.78-0.98, p = 0.02)。经风险调整的死亡率在接受外科医生和非外科医生ttl护理的患者之间无显著差异(OR 0.92, 95% CI 0.80-1.06, p = 0.23)。此外,我们没有观察到任何评估亚组的风险调整死亡率的差异。结论:经风险调整后,外科和非外科ttl治疗的创伤患者死亡率无差异。我们的研究支持急诊医生在一级创伤中心扮演TTL的角色。
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引用次数: 1
Inhaled nitrous oxide for painful procedures in children and youth: a systematic review and meta-analysis. 吸入一氧化二氮治疗儿童和青少年疼痛:系统回顾和荟萃分析。
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s43678-023-00507-0
Naveen Poonai, Christopher Creene, Ariel Dobrowlanski, Rishika Geda, Lisa Hartling, Samina Ali, Maala Bhatt, Evelyne D Trottier, Vikram Sabhaney, Katie O'Hearn, Rini Jain, Martin H Osmond

Objectives: The objective of this study was to synthesize indication-based evidence for N2O for distress and pain in children.

Study design: We included trials of N2O in participants 0-21 years, reporting distress or pain for emergency department procedures. The primary outcome was procedural distress. Where meta-analysis was not possible, we used Tricco et al.'s classification of "neutral" (p ≥ 0.05), "favorable," or "unfavorable" (p < 0.05, supporting N2O or comparator, respectively). We used the Cochrane Collaboration's Risk of Bias tool and the Grading of Recommendations Assessment, Development, and Evaluation system to evaluate risk of bias and quality of evidence, respectively.

Results: We included 30 trials. For pain using the Visual Analog Scale (0-100 mm) during IV insertion, 70% N2O (delta:-16.5; 95%CI:-28.6 to -4.4; p = 0.008; three trials; I2 = 0%) and 50% N2O plus eutectic mixture of local anesthetics (EMLA) (delta:-1.2; 95%CI:-2.1 to -0.3; p = 0.007; two trials; I2 = 43%) were superior to EMLA. 50% N2O was not superior to EMLA (delta:-0.4; 95%CI:-1.2 to 0.3; p = 0.26; two trials; I2 = 15%). For distress and pain during laceration repair, N2O was "favorable" versus each of SC lidocaine, oxygen, and oral midazolam but "neutral" versus IV ketamine (five trials). For distress and pain during fracture reduction (three trials), N2O was "neutral" versus each of IM meperidine plus promethazine, regional anesthesia, and IV ketamine plus midazolam. For distress and pain during lumbar puncture (one trial), N2O was "favorable" versus oxygen. For distress and pain during urethral catheterization (one trial), N2O was "neutral" versus oral midazolam. For pain during intramuscular injection (one trial), N2O plus EMLA was "favorable" versus N2O and EMLA alone. Common adverse effects of N2O included nausea (4.4%), agitation (3.7%), and vomiting (3.6%) AEs were less frequent with N2O alone (278/1147 (24.2%)) versus N2O plus midazolam (48/52 (92.3%)) and N2O plus fentanyl (123/201 (61.2%)).

Conclusions: There is sufficient evidence to recommend N2O plus topical anesthetic for IV insertion and laceration repair. Adverse effects are greater when combined with other sedating agents.

目的:本研究的目的是综合N2O治疗儿童苦恼和疼痛的适应症证据。研究设计:我们纳入了0-21岁参与者的N2O试验,这些参与者报告了急诊科手术的痛苦或痛苦。主要结果是程序性痛苦。在无法进行荟萃分析的情况下,我们使用Tricco等人的分类:“中性”(p≥0.05)、“有利”或“不利”(分别为p 20或比较者)。我们使用Cochrane协作的偏倚风险工具和分级推荐评估、发展和评价系统分别评估偏倚风险和证据质量。结果:我们纳入了30项试验。静脉注射期间疼痛使用视觉模拟量表(0-100 mm), 70% N2O (δ:-16.5;95%CI:-28.6 ~ -4.4;p = 0.008;三个试验;I2 = 0%)和50% N2O加共晶局部麻醉剂(EMLA)混合物(δ:-1.2;95%CI:-2.1 ~ -0.3;p = 0.007;两个试验;I2 = 43%)优于EMLA。50% N2O不优于EMLA (δ:-0.4;95%CI:-1.2 ~ 0.3;p = 0.26;两个试验;i2 = 15%)。对于撕裂伤修复期间的窘迫和疼痛,N2O与SC利多卡因、氧和口服咪达唑仑相比“有利”,但与IV氯胺酮相比“中性”(5项试验)。对于骨折复位期间的窘迫和疼痛(三个试验),N2O与IM哌嗪加异丙嗪、区域麻醉和IV氯胺酮加咪达唑仑相比是“中性的”。对于腰椎穿刺时的窘迫和疼痛(一项试验),N2O比氧气“有利”。对于导尿期间的窘迫和疼痛(一项试验),N2O与口服咪达唑仑相比是“中性的”。对于肌肉注射期间的疼痛(一项试验),N2O加EMLA比N2O和EMLA单独“有利”。N2O的常见不良反应包括恶心(4.4%)、躁动(3.7%)和呕吐(3.6%)。与N2O联合咪达唑仑(48/52(92.3%))和N2O联合芬太尼(123/201(61.2%))相比,N2O单独使用的不良反应发生率(278/1147(24.2%))较低。结论:有足够的证据推荐N2O加表面麻醉剂用于静脉插入和伤口修复。与其他镇静剂合用时,副作用更大。
{"title":"Inhaled nitrous oxide for painful procedures in children and youth: a systematic review and meta-analysis.","authors":"Naveen Poonai,&nbsp;Christopher Creene,&nbsp;Ariel Dobrowlanski,&nbsp;Rishika Geda,&nbsp;Lisa Hartling,&nbsp;Samina Ali,&nbsp;Maala Bhatt,&nbsp;Evelyne D Trottier,&nbsp;Vikram Sabhaney,&nbsp;Katie O'Hearn,&nbsp;Rini Jain,&nbsp;Martin H Osmond","doi":"10.1007/s43678-023-00507-0","DOIUrl":"https://doi.org/10.1007/s43678-023-00507-0","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to synthesize indication-based evidence for N<sub>2</sub>O for distress and pain in children.</p><p><strong>Study design: </strong>We included trials of N<sub>2</sub>O in participants 0-21 years, reporting distress or pain for emergency department procedures. The primary outcome was procedural distress. Where meta-analysis was not possible, we used Tricco et al.'s classification of \"neutral\" (p ≥ 0.05), \"favorable,\" or \"unfavorable\" (p < 0.05, supporting N<sub>2</sub>O or comparator, respectively). We used the Cochrane Collaboration's Risk of Bias tool and the Grading of Recommendations Assessment, Development, and Evaluation system to evaluate risk of bias and quality of evidence, respectively.</p><p><strong>Results: </strong>We included 30 trials. For pain using the Visual Analog Scale (0-100 mm) during IV insertion, 70% N<sub>2</sub>O (delta:-16.5; 95%CI:-28.6 to -4.4; p = 0.008; three trials; I<sup>2</sup> = 0%) and 50% N<sub>2</sub>O plus eutectic mixture of local anesthetics (EMLA) (delta:-1.2; 95%CI:-2.1 to -0.3; p = 0.007; two trials; I<sup>2</sup> = 43%) were superior to EMLA. 50% N<sub>2</sub>O was not superior to EMLA (delta:-0.4; 95%CI:-1.2 to 0.3; p = 0.26; two trials; I<sup>2</sup> = 15%). For distress and pain during laceration repair, N<sub>2</sub>O was \"favorable\" versus each of SC lidocaine, oxygen, and oral midazolam but \"neutral\" versus IV ketamine (five trials). For distress and pain during fracture reduction (three trials), N<sub>2</sub>O was \"neutral\" versus each of IM meperidine plus promethazine, regional anesthesia, and IV ketamine plus midazolam. For distress and pain during lumbar puncture (one trial), N<sub>2</sub>O was \"favorable\" versus oxygen. For distress and pain during urethral catheterization (one trial), N<sub>2</sub>O was \"neutral\" versus oral midazolam. For pain during intramuscular injection (one trial), N<sub>2</sub>O plus EMLA was \"favorable\" versus N<sub>2</sub>O and EMLA alone. Common adverse effects of N<sub>2</sub>O included nausea (4.4%), agitation (3.7%), and vomiting (3.6%) AEs were less frequent with N<sub>2</sub>O alone (278/1147 (24.2%)) versus N<sub>2</sub>O plus midazolam (48/52 (92.3%)) and N<sub>2</sub>O plus fentanyl (123/201 (61.2%)).</p><p><strong>Conclusions: </strong>There is sufficient evidence to recommend N<sub>2</sub>O plus topical anesthetic for IV insertion and laceration repair. Adverse effects are greater when combined with other sedating agents.</p>","PeriodicalId":55286,"journal":{"name":"Canadian Journal of Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9629609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Global Research Highlights. 全球研究亮点。
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s43678-023-00532-z
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引用次数: 0
Application of the Modified Early Obstetrical Warning System (MEOWS) in postpartum patients in the emergency department. 改进的产科早期预警系统(MEOWS)在急诊科产后患者中的应用
IF 2.4 4区 医学 Q2 Medicine Pub Date : 2023-06-01 DOI: 10.1007/s43678-023-00500-7
Jeeventh Kaur, Cameron Thompson, Shelley McLeod, Catherine Varner

Introduction: Over the last two decades, there has been a steady rise in severe maternal morbidity and pregnancy-related deaths in Canada and the USA. The Modified Early Obstetric Warning System (MEOWS) is a risk stratification tool designed to predict severe maternal morbidity and mortality and has been validated for use in obstetrical wards. The objective of this study was to determine if MEOWS could accurately identify patients at risk of severe maternal morbidity and mortality in the ED setting.

Methods: This was a chart review of patients presenting to an academic tertiary care centre (annual ED census 65,000) with a postpartum complaint within 6 weeks of delivery between May 2020 and March 2022. The exposure was the presence of a trigger, defined as one severely abnormal (red) or two mildly abnormal (yellow) physiological measurements during the ED visit. The diagnostic accuracy of the tool to identify patients at risk of severe maternal morbidity severe maternal morbidity or mortality was estimated by calculating the sensitivity, specificity, positive predictive value and negative predictive value.

Results: Two hundred and sixty-seven patients were included, of which 21 (7.9%) met the criteria for severe maternal morbidity. There were no maternal deaths. Overall, the sensitivity of the MEOWS tool was 85.7% (95% CI 63.7-97.0%), specificity was 67.9% (95% CI 61.7-73.7%), positive predictive value was 18.6% (95% CI 15.1-22.7%), and negative predictive value was 98.2% (95% CI 95.1-99.4%). Severe preeclampsia and eclampsia were the most common outcome category of severe maternal morbidity, representing 16 (76.2%) cases. Most patients (86.5%) were discharged directly from the ED, and 90.0% did not return within 30 days.

Conclusions: This study is the first to explore the utility of MEOWS in postpartum ED patients. The presence of a MEOWS trigger at ED triage or the first ED nursing assessment was associated with severe maternal morbidity. Thus, MEOWS may be a valuable tool to identify postpartum patients at risk of severe outcomes early in an ED visit.

引言:在过去的二十年中,在加拿大和美国,严重的孕产妇发病率和与妊娠有关的死亡一直在稳步上升。改进的早期产科预警系统(MEOWS)是一种风险分层工具,旨在预测严重的孕产妇发病率和死亡率,并已被证实可用于产科病房。本研究的目的是确定MEOWS是否能准确识别急诊科环境中有严重孕产妇发病和死亡风险的患者。方法:这是对2020年5月至2022年3月期间,在一个学术三级保健中心(每年ED普查65,000例)分娩6周内出现产后投诉的患者进行的图表回顾。暴露是一个触发器的存在,定义为在急诊科就诊期间一次严重异常(红色)或两次轻度异常(黄色)的生理测量。通过计算敏感性、特异性、阳性预测值和阴性预测值,评估该工具对存在严重孕产妇发病或死亡风险患者的诊断准确性。结果:共纳入267例患者,其中21例(7.9%)符合重度孕产妇发病标准。没有产妇死亡。总体而言,MEOWS工具的敏感性为85.7% (95% CI 63.7 ~ 97.0%),特异性为67.9% (95% CI 61.7 ~ 73.7%),阳性预测值为18.6% (95% CI 15.1 ~ 22.7%),阴性预测值为98.2% (95% CI 95.1 ~ 99.4%)。重度先兆子痫和子痫是最常见的严重产妇发病的结局类别,占16例(76.2%)。大多数患者(86.5%)直接从急诊科出院,90.0%在30天内未返回。结论:本研究首次探讨了MEOWS在产后ED患者中的应用。在急诊科分诊或第一次急诊科护理评估时出现MEOWS触发与严重的产妇发病率相关。因此,MEOWS可能是一种有价值的工具,可以在急诊室就诊早期识别有严重后果风险的产后患者。
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引用次数: 1
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Canadian Journal of Emergency Medicine
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