Pub Date : 1948-04-01DOI: 10.1111/j.1365-2133.1948.tb11009.x
S LOMHOLT
THE German occupation of Denmark prevented us from learning about the works of Charpy and Dowling until the summer of 1946, so out experiments with this form of treatment did not commence until a year ago. During this past year, on the other hand, we have treated all our lupus patients with vitamin D, and I am happy to be able to state that the result has been excellent. It will be appropriate to mention that with the Finsen treatment—^with concentrated carbon arc light and heliotherapy—^we had attained a recovery percentage of 80, and consequently the remaining 20% of the lupus patients to be treated with calciferol constituted a particularly crucial test for the new method. In the past year we have treated altogether 130 cases, and the difficulty will be evident from the long duration of the disease in these cases.
{"title":"Vitamin D therapy in cutaneous tuberculosis.","authors":"S LOMHOLT","doi":"10.1111/j.1365-2133.1948.tb11009.x","DOIUrl":"https://doi.org/10.1111/j.1365-2133.1948.tb11009.x","url":null,"abstract":"THE German occupation of Denmark prevented us from learning about the works of Charpy and Dowling until the summer of 1946, so out experiments with this form of treatment did not commence until a year ago. During this past year, on the other hand, we have treated all our lupus patients with vitamin D, and I am happy to be able to state that the result has been excellent. It will be appropriate to mention that with the Finsen treatment—^with concentrated carbon arc light and heliotherapy—^we had attained a recovery percentage of 80, and consequently the remaining 20% of the lupus patients to be treated with calciferol constituted a particularly crucial test for the new method. In the past year we have treated altogether 130 cases, and the difficulty will be evident from the long duration of the disease in these cases.","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-2133.1948.tb11009.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27728958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1948-04-01DOI: 10.1111/j.1365-2133.1948.tb11008.x
G B DOWLING
phate ions from phosphoric esters. The increase of available phosphate ions is of great importance. The Americans, Schapiro and Wertheimer, have demonstrated in many animal tissues a ferment which acts on the phospholipides and destroys the higher fatty acids. This ferment requires for its activity the presence of phosphate radicals and muscle adenjdic acid. It is inactivated by oxygen. Koch's bacillus is particularly rich in lipoids of great complexity, waxes as well as fatty acids, both free and in combination as phosphatides. It seemed possible that some such ferment might have some lytic action on the tubercle baciUus, and might he activated by phosphate ions made available by vitamin D. It was desirable therefore to investigate the action of added adenylic acid on the therapeutic properties of vitamin D. This I was able to accomplish in a case of extensive tuberculous ulceration in which the combination of vitamin Dg with local application of adenylic acid resulted in the disappearance within a few hours of all tubercle bacilli from the lesion. Perhaps the failure in pulmonary tuberculosis is due to the inhibition of the ferment by the high oxygen tension.
{"title":"Vitamin D in the treatment of cutaneous tuberculosis.","authors":"G B DOWLING","doi":"10.1111/j.1365-2133.1948.tb11008.x","DOIUrl":"https://doi.org/10.1111/j.1365-2133.1948.tb11008.x","url":null,"abstract":"phate ions from phosphoric esters. The increase of available phosphate ions is of great importance. The Americans, Schapiro and Wertheimer, have demonstrated in many animal tissues a ferment which acts on the phospholipides and destroys the higher fatty acids. This ferment requires for its activity the presence of phosphate radicals and muscle adenjdic acid. It is inactivated by oxygen. Koch's bacillus is particularly rich in lipoids of great complexity, waxes as well as fatty acids, both free and in combination as phosphatides. It seemed possible that some such ferment might have some lytic action on the tubercle baciUus, and might he activated by phosphate ions made available by vitamin D. It was desirable therefore to investigate the action of added adenylic acid on the therapeutic properties of vitamin D. This I was able to accomplish in a case of extensive tuberculous ulceration in which the combination of vitamin Dg with local application of adenylic acid resulted in the disappearance within a few hours of all tubercle bacilli from the lesion. Perhaps the failure in pulmonary tuberculosis is due to the inhibition of the ferment by the high oxygen tension.","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-2133.1948.tb11008.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27728957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1948-04-01DOI: 10.1111/j.1365-2133.1948.tb11007.x
J CHARPY
{"title":"Vitamin D2 in the treatment of cutaneous tuberculosis.","authors":"J CHARPY","doi":"10.1111/j.1365-2133.1948.tb11007.x","DOIUrl":"https://doi.org/10.1111/j.1365-2133.1948.tb11007.x","url":null,"abstract":"","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1365-2133.1948.tb11007.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27728956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Self-inflicted lesions in twins.","authors":"H MACCORMAC","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27779330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intra-epithelial epithelioma.","authors":"F R BETTLEY","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27779332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phyto-photo-dermatitis, due to parsnips.","authors":"C H WHITTLE","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27779331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple superficial rodent ulcers following long continued arsenic therapy.","authors":"B RUSSELL, O JOHN","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27779333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Baldness associated with uveitis and deafness (Vogt).","authors":"H T H WILSON, F R BETTLEY","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27779334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lipoid rheumatism.","authors":"F P WEBER","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":55324,"journal":{"name":"British Journal of Dermatology and Syphilis","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1948-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27803876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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