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Aggressive psammomatoid ossifying fibroma of the inferior turbinate and lateral nasal wall. 下鼻甲及侧鼻壁侵袭性沙沫样骨化纤维瘤。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
V Danielides, K Ingels, G Patrikakos, P C M de Wilde

Objective: Fibroosseous lesions are rare entities of the nose and paranasal sinuses, the terminology and classification of which are still confusing. Psammomatoid or aggressive (juvenile) ossifying fibroma is a benign messenchymal tumor usually met in the young age (5-15 years), in the sinonasal tract, bearing distinctive histomorphologic features and a tendency towards locally aggressive behaviour.

Methodology: We report here a rare case of an aggressive psammomatoid ossifying fibroma of the inferior turbinate and the lateral nasal wall, with obstruction of the nasolacrimal duct, in a 68-year-old woman.

Results: Diagnosis was based on physical examination, CT scan imaging and histopathological examination. Treatment consisted of endoscopic intranasal resection of the tumor accompanied by removal of the lateral nasal wall.

Conclusions: Fibro-osseous tumors of the nose and paranasal sinuses require aggressive surgical approach in order to avoid recurrence. Complete surgical excision may not always be possible mainly due to the tumor's extent and location.

目的:纤维骨性病变是鼻窦和副鼻窦的罕见病变,其术语和分类仍很混乱。沙瘤样骨化纤维瘤或侵袭性(青少年)骨化纤维瘤是一种良性间质肿瘤,通常发生在5-15岁的鼻窦,具有独特的组织形态学特征和局部侵袭性倾向。方法:我们在此报告一例罕见的下鼻甲和鼻侧壁侵袭性沙沫样骨化纤维瘤,合并鼻泪管阻塞,患者为68岁女性。结果:诊断依据为体格检查、CT扫描成像及组织病理学检查。治疗包括鼻内窥镜切除肿瘤并切除鼻侧壁。结论:鼻及副鼻窦纤维性骨肿瘤需要积极的手术治疗以避免复发。由于肿瘤的范围和位置,完全手术切除可能并不总是可行的。
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引用次数: 0
Anatomophysiology of the central auditory nervous system: basic concepts. 中枢听觉神经系统的解剖生理学:基本概念。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
J P Demanez, L Demanez

The purpose of this review is to provide an overview of the central auditory nervous system (CANS). Three main relay nuclei are located between the auditory nerve and the primary auditory cerebral cortex: 1- the cochlear nucleus, 2- the contralateral inferior colliculus and 3- the contralateral medial geniculate body. Some fibers of this main ascending pathway branch off to other nuclei such as the nuclei of the superior olivary complex and the nucleus of the lateral lemniscus. Fiber tracts connect the two sides of the ascending pathway at several levels, in such a manner that each ear projects heavier to the contralateral temporal cortex. As sensory information travels within the CANS, its processing occurs not only in a serial order but also in a parallel manner resulting a highly efficient and redundant system. Finally, this review put forth a model of central auditory processing that can serve as the basis for evaluating and addressing the needs of eventual revalidation.

本综述的目的是提供中枢听觉神经系统(can)的概述。三个主要的中继核位于听神经和初级听觉大脑皮层之间:1-耳蜗核,2-对侧下丘和3-对侧内侧膝状体。这条主要上行通路的一些纤维分支到其他核,如上橄榄复合体核和外侧小扁豆核。纤维束在几个层次上连接上升通道的两侧,以这样的方式,每只耳朵向对侧颞叶皮层投射更重。当感知信息在can内传播时,其处理不仅以串行顺序发生,而且以并行方式发生,从而形成一个高效和冗余的系统。最后,本文提出了一个中央听觉加工模型,该模型可以作为评估和解决最终再验证需求的基础。
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引用次数: 0
Velo-cardio-facial syndrome: guidelines for diagnosis, treatment and follow-up of ent manifestations. Velo-cardio-facial综合征:诊断、治疗及随访指南。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
G Vantrappen, N Rommel, A Swillen, C W Cremers, J P Fryns, K Devriendt

The Velo-Cardio-Facial Syndrome (VCFS), caused by a submicroscopic deletion in the long arm of chromosome 22, has a broad clinical spectrum of ENT manifestations including for instance velopharyngeal dysfunction, hearing problems and laryngotracheal anomalies. In the current report we present guidelines for diagnosis, treatment and follow-up of the ENT manifestations in patients with a deletion 22q11, based on our experience and the literature.

由22号染色体长臂亚显微缺失引起的Velo-Cardio-Facial Syndrome (VCFS)具有广泛的耳鼻喉科临床表现,包括例如velo -咽功能障碍,听力问题和喉气管异常。在目前的报告中,我们根据我们的经验和文献,提出了诊断、治疗和随访22q11缺失患者耳鼻喉科表现的指南。
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引用次数: 0
Assessment of patient benefit from septo-rhinoplasty with the use of Glasgow Benefit Inventory (GBI) and Nasal Symptom Questionnaire (NSQ). 使用格拉斯哥获益量表(GBI)和鼻症状问卷(NSQ)评估鼻中隔成形术患者的获益。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
I Konstantinidis, S Triaridis, A Printza, A Triaridis, G Noussios, K Karagiannidis

Septorhinoplasty is the most difficult and complicated procedure in facial plastic surgery. Because of the complex interdependency of the anatomical parts, alteration of one may have an impact on another. Form and function are completely interwoven in septorhinoplasty. The selection of appropriate candidates involves an understanding of their expectations. Outcome research is a new concept in clinical medicine and its importance is increasingly recognized for the patient management and policy decisions. This study includes an analysis of patients' subjective opinion of the surgical outcome after septo-rhinoplasty, with the use of Glasgow Benefit Inventory (postoperatively) and the Nasal Symptom Questionnaire (pre- and postoperatively). In this study we analyze the patient subjective rating of benefit in 41 consecutive patients who underwent septo-rhinoplasty within the first 8 months of 2001, and had completed a follow up period of more than 6 months postoperatively. The early complication rate was recorded and analyzed along with data regarding the patient satisfaction rate using GBI and NSQ. The response rate was 80%, which is high. Patients had significant improvement in all subscales of GBI (General, Social, Physical) related with a decreased number of nasal symptoms postoperatively and a good aesthetic result.

鼻中隔成形术是面部整形手术中最困难、最复杂的手术。由于解剖部位之间复杂的相互依赖关系,一个部位的改变可能对另一个部位产生影响。在鼻中隔成形术中,形式和功能完全交织在一起。选择合适的候选人需要了解他们的期望。结果研究是临床医学中的一个新概念,它对患者管理和决策的重要性日益得到认识。本研究包括分析患者对鼻中隔成形术后手术结果的主观意见,使用格拉斯哥获益量表(术后)和鼻症状问卷(术前和术后)。在这项研究中,我们分析了41名在2001年的前8个月内连续接受鼻中隔成形术的患者的主观评价,并完成了术后6个多月的随访。记录并分析早期并发症发生率,以及使用GBI和NSQ的患者满意度数据。应答率为80%,这是很高的。患者在GBI的所有亚量表(一般、社会、身体)中均有显著改善,术后鼻症状减少,美观效果良好。
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引用次数: 0
Qualitative and quantitative studies in electron microscopy on influence of experimental ischemia of the vertebral arteries on the outer hair cells function in guinea pigs. 实验性椎动脉缺血对豚鼠外毛细胞功能影响的电镜定性和定量研究。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
J Olszewski, W Chudzik, J Miłoński, K Kuśmierczyk

Histological studies were performed in 20 guinea pigs, both sexes, weighing 250-300 g and divided into two groups: I--control (anaesthetized animals without surgery), II--examined (in anaesthetized animals through an incision of the skin and muscles of the neck), the left or right vertebral artery was exposed and a vascular clip was inserted into the foramen of the transverse process of the 2-nd cervical vertebra. 50 days after this procedure, the guinea pigs were again anaesthetized by intraperitoneal injection of 35% solution of chloral hydrate, then vascular and cochlear perfusion with 3.6% solution of glutaraldehyde was performed. Simultaneously, by means of micropreparation, samples of cochlea were made for electron studies by means of electron microscope (Philips EM 300). In qualitative histopathologic examinations in guinea pigs of II group, the ischemia changes of the outer hair cells were greater in the side of irritation of the vertebral artery than at the opposite side. At the receptor side of these cells, under the membrane, there are multilamellar outgrowths in the shape of cisterns, partly expanded. The relative volume of external compartment of mitochondria in control group is as follows respectively: 0.15 +/- 0.0% at the right side and 0.15 +/- 0.08% at the left side, and in II group, respectively: 0.22 +/- 0.06% at the side of irritation and 0.19 +/- 0.07% at the opposite side. The obtained data in electron microscopy, both qualitative and quantitative pointed at ischemia changes of outer hair cells in guinea pigs after prolonged irritation of periarterial plexus of vertebral artery.

对体重250-300 g的20只雄性豚鼠进行组织学研究,分为两组:I-对照组(未手术麻醉的动物),II-检查组(通过颈部皮肤和肌肉切口麻醉的动物),暴露左或右椎动脉,并将血管夹插入第2颈椎横突孔。术后50 d,再次腹腔注射35%水合氯醛溶液麻醉豚鼠,然后用3.6%戊二醛溶液灌注血管和耳蜗。同时,采用显微法制备耳蜗标本,在Philips em300电镜下进行电子观察。在II组豚鼠的定性组织病理学检查中,椎动脉刺激侧外毛细胞的缺血变化明显大于对侧。在这些细胞的受体一侧,在膜下,有池状的多层增生,部分扩张。对照组线粒体外室相对体积右侧为0.15 +/- 0.0%,左侧为0.15 +/- 0.08%,II组刺激侧为0.22 +/- 0.06%,刺激侧为0.19 +/- 0.07%。电镜下的定性和定量数据均显示了长时间刺激椎动脉动脉丛后豚鼠外毛细胞的缺血变化。
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引用次数: 0
Congenital laryngeal cyst: a case report. 先天性喉囊肿1例。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
S Mariën, A Jespers, G Vidts, B Schmelzer

Congenital laryngeal cysts are a rare cause of stridor in the neonate. Nevertheless, delayed diagnosis and treatment can cause life-threatening airway obstruction. Even though the diagnosis is easily made by careful inspection, treatment results often in recurrence. These facts are illustrated by a case of a baby with a saccular cyst. Immediately after diagnosis and 5 days later the cyst was de-roofed using a CO2 laser via an endolaryngeal approach. Because of a second recurrence an excision of the cyst was performed via a lateral cervical approach.

摘要先天性喉囊肿是引起新生儿喘鸣的罕见原因。然而,延误的诊断和治疗可能导致危及生命的气道阻塞。尽管通过仔细的检查很容易诊断,但治疗的结果往往是复发。这些事实是由一个婴儿与一个囊性囊肿的情况说明。诊断后5天,囊肿立即通过鼻内入路用CO2激光去顶。由于第二次复发,囊肿切除通过宫颈外侧入路进行。
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引用次数: 0
The role of evoked potentials (EPs) in the assessment of the human central auditory nervous system (CANS). 诱发电位(EPs)在评估人中枢听觉神经系统(can)中的作用。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
P Deltenre, C Colin, B Dachy, A L Mansbach

This paper presents an overview of the use of EPs in the assessment of the CANS. Emphasis is laid on recent developments and research efforts centered on appraising how the auditory neural code is processed by the central pathways. It is shown how, in addition to their classical site-of-lesion testing role, EPs can, especially when combined with ecological (mostly speech-like) stimuli, yield highly valuable information on the neurophysiological processes leading to the perception of auditory objects as well as speech. Special space is devoted to the Mismatch Negativity that currently provides the only objective measure of the accuracy with which the CANS detects auditory and phonetic contrasts.

本文概述了EPs在can评估中的应用。重点放在最近的发展和研究工作集中在评估听觉神经密码是如何被中央通路处理。研究表明,除了经典的损伤部位测试作用外,EPs还可以,特别是当与生态(主要是言语类)刺激相结合时,在导致听觉对象和言语感知的神经生理过程中产生非常有价值的信息。特别的空间专门用于错配否定,目前提供了唯一的客观衡量准确度与can检测听觉和语音对比。
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引用次数: 0
Speech recognition tests in sensorineural hearing loss. 感音神经性听力损失的语音识别试验。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
K Vermeire, J P Brokx, N Lemkens, P D'Haese, P H Van de Heyning

The ability to understand speech must be considered the most important measurable aspect of human auditory function. Due to the innovative developments in hearing aids and cochlear implants, there has been a renewed interest in speech recognition testing. During recent years, the start of several multi-centre studies have increased the urge to come to some consensus on the use of different speech materials. In this article a global overview of existing types of speech material in Dutch will be given. For each type, there is a reference to similar speech audiometric tests in French, English and German.

理解语言的能力必须被认为是人类听觉功能中最重要的可测量方面。由于助听器和人工耳蜗的创新发展,人们对语音识别测试重新产生了兴趣。近年来,几项多中心研究的开始,增加了对不同语言材料使用达成某种共识的冲动。在这篇文章中,将给出荷兰语中现有语音材料类型的全球概述。对于每种类型,都参考了法语、英语和德语的类似语音听力测试。
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引用次数: 0
Bacteriology of chronic suppurative otitis media in congolese children. 刚果儿童慢性化脓性中耳炎的细菌学研究。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
D T Nyembue, J M Tshiswaka, M J Sabue, C K Muyunga

Aim: The study intended to identify bacteria active in the chronic suppurative otitis media and to determine their sensitivity to current antibiotics.

Methods: After clinical evaluation, middle-ear secretions were taken for bacteriological examination from 78 children meeting the inclusion criteria. All children with cholesteatoma and those with tumors occluding the ear canal were excluded.

Results: The most frequent isolated germs, in descending order frequency, were as follows: Proteus mirabilis (23%), Pseudomonas aeruginosa (22%), Citrobacter (20%) and Salmonella (5%). There were no cases of mixed flora. Ofloxacin was susceptible on all isolates. Neomycin, gentamicin and polymyxin B were susceptible on 96%, 83% and 67% of the isolates respectively. All isolates were resistant to amoxycillin.

Conclusion: Peudomonas, Proteus and Citrobacter are the most common causes of chronic otitis media among children in our community of congolese children. Ofloxacin and neomycin are the most highly effective against most of the isolated germs, and are therefore recommended as the first line local treatment. Amoxycillin and chloramphenicol should be avoided.

目的:本研究旨在鉴定慢性化脓性中耳炎中活跃的细菌,并确定其对现有抗生素的敏感性。方法:经临床评价,对78例符合纳入标准的患儿中耳分泌物进行细菌学检查。排除所有患有胆脂瘤和肿瘤阻塞耳道的儿童。结果:检出频率由高到低依次为奇异变形杆菌(23%)、铜绿假单胞菌(22%)、柠檬酸杆菌(20%)和沙门氏菌(5%)。没有混合菌群的情况。氧氟沙星对所有分离株均敏感。新霉素、庆大霉素和多粘菌素B的敏感性分别为96%、83%和67%。所有分离株均对阿莫西林耐药。结论:假单胞菌、变形杆菌和柠檬酸杆菌是我们社区刚果儿童慢性中耳炎最常见的病因。氧氟沙星和新霉素对大多数分离的细菌最有效,因此建议作为一线局部治疗。应避免使用阿莫西林和氯霉素。
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引用次数: 0
Central auditory processing assessment. 中央听觉处理评估。
IF 0.2 4区 医学 Q3 Medicine Pub Date : 2003-01-01
L Demanez, J P Demanez

As the acoustic information travels within the central auditory nervous system, the processing of the signal undergoes several levels of serial and parallel "bottom-up" processing influenced by high level cognitive "top-down" processes. Because the multiple location of the operational sites, the central auditory deficits are frequently quite subtle and need a test battery approach to be identified. Each of the four principal processes has at least to be tested: the closure task, the dichotic ability, the temporal ordering task and the binaural interaction function. The purpose of this review is to provide an overview of the psychoacoustic test procedures of identifying lesions or dysfunction's in the central auditory system.

当声音信息在中枢听觉神经系统内传播时,信号的处理经历了几个层次的串行和并行的“自下而上”处理,受到高层次认知“自上而下”处理的影响。由于操作部位的多个位置,中枢听觉缺陷通常是非常微妙的,需要测试电池的方法来识别。四个主要过程中的每一个都至少需要测试:关闭任务,二分能力,时间排序任务和双耳交互功能。本综述的目的是提供一个概述的心理声学测试程序识别病变或功能障碍的中央听觉系统。
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引用次数: 0
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