Pub Date : 2022-01-01DOI: 10.30546/1683-6154.21.3.2022.349
{"title":"Final Report of COIA 2022","authors":"","doi":"10.30546/1683-6154.21.3.2022.349","DOIUrl":"https://doi.org/10.30546/1683-6154.21.3.2022.349","url":null,"abstract":"","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"31 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75020221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.11648/j.acm.20221101.11
R. Mayes, David Owens, J. Dauer, Kent Rittschof
{"title":"A Quantitative Reasoning Framework and the Importance of Quantitative Modeling in Biology","authors":"R. Mayes, David Owens, J. Dauer, Kent Rittschof","doi":"10.11648/j.acm.20221101.11","DOIUrl":"https://doi.org/10.11648/j.acm.20221101.11","url":null,"abstract":"","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"19 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84387979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.11648/j.acm.20221101.13
Binlin Dai, Zekun Li
{"title":"Discrete Probability of Random Möbius Groups: Random Subgroups by Two Generators","authors":"Binlin Dai, Zekun Li","doi":"10.11648/j.acm.20221101.13","DOIUrl":"https://doi.org/10.11648/j.acm.20221101.13","url":null,"abstract":"","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"7 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89663084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.30546/1683-6154.21.3.2022.317
{"title":"Constructions of Input and Output Isoquants in DEA Models with Selective Convexity","authors":"","doi":"10.30546/1683-6154.21.3.2022.317","DOIUrl":"https://doi.org/10.30546/1683-6154.21.3.2022.317","url":null,"abstract":"","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"40 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73628349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.30546/1683-6154.21.3.2022.329
{"title":"Some Ostrowski-Mercer Type Inequalities for Differentiable Convex Functions via Fractional Integral Operators with Strong Kernels","authors":"","doi":"10.30546/1683-6154.21.3.2022.329","DOIUrl":"https://doi.org/10.30546/1683-6154.21.3.2022.329","url":null,"abstract":"","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"42 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73092189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.30546/1683-6154.21.3.2022.246
{"title":"Nanosatellite Attitude Estimation in Sun and Eclipse Periods without Gyroscopes","authors":"","doi":"10.30546/1683-6154.21.3.2022.246","DOIUrl":"https://doi.org/10.30546/1683-6154.21.3.2022.246","url":null,"abstract":"","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"12 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82003428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This document was an opportunity for us to measure the contributions of researchers on the asymptotic behavior of the extremes random variables. Beyond the available results, we have proposed an analysis of the behavior of the extremes of random variables of geometric type. We succeeded in determining a subsequence which allows us to establish a convergence in law of the extremes of this type of random variable while passing by the determination of a speed of convergence. We then exposed the limited law which results from it then we called upon the copulas of the extreme values to propose a joint limited law for two independent samples of random variables of geometric type. These results will allow us to analyze, in a document, not only the convergence in moment of order of the other extremes of the random variables of geometric type but also the general asymptotic behavior of the extremes of a serie of random variables with integer value. This document was an opportunity for us to measure the contributions of researchers on the asymptotic behavior of the extremes random variables. Beyond the available results, we have proposed an analysis of the behavior of the extremes of random variables of geometric type. We first made the case of the fact that the random variables of geometric type could be constructed from the random variables of exponential distribution and that they were not only integer variables but also that in general there were no sequences standards that allowed their extremes to converge. To do this, we first built a convergent ϕ(k) subsequence which we then used to define a geometric type Tϕ(k) subsequence of random variables. We have also proved the convergence in distribution of the extremes of the random variables Tϕ(k). We have also exhibited the resulting limit law. Finally, in this document, we have dealt with the multivariate case of random variables of geometric type. We considered two independent samples of random variables of geometric types. Using a copula of extreme values, in particular the logistic copula, we proposed a joint limit distribution of two independent samples of subsequences of geometric type random variables. We then exposed the limited law which results from it then we called upon the copulas of the extreme values to propose a joint limited law for two independent samples of random variables of geometric type.
{"title":"Asymptotic Behavior of Multivariate Extremes Geometric Type Random Variables","authors":"Frédéric Béré, Kpèbbèwèrè Cédric Somé, Remi Guillaume Bagré, Pierre Clovis Nitiéma","doi":"10.11648/J.ACM.20211006.12","DOIUrl":"https://doi.org/10.11648/J.ACM.20211006.12","url":null,"abstract":"This document was an opportunity for us to measure the contributions of researchers on the asymptotic behavior of the extremes random variables. Beyond the available results, we have proposed an analysis of the behavior of the extremes of random variables of geometric type. We succeeded in determining a subsequence which allows us to establish a convergence in law of the extremes of this type of random variable while passing by the determination of a speed of convergence. We then exposed the limited law which results from it then we called upon the copulas of the extreme values to propose a joint limited law for two independent samples of random variables of geometric type. These results will allow us to analyze, in a document, not only the convergence in moment of order of the other extremes of the random variables of geometric type but also the general asymptotic behavior of the extremes of a serie of random variables with integer value. This document was an opportunity for us to measure the contributions of researchers on the asymptotic behavior of the extremes random variables. Beyond the available results, we have proposed an analysis of the behavior of the extremes of random variables of geometric type. We first made the case of the fact that the random variables of geometric type could be constructed from the random variables of exponential distribution and that they were not only integer variables but also that in general there were no sequences standards that allowed their extremes to converge. To do this, we first built a convergent ϕ(k) subsequence which we then used to define a geometric type Tϕ(k) subsequence of random variables. We have also proved the convergence in distribution of the extremes of the random variables Tϕ(k). We have also exhibited the resulting limit law. Finally, in this document, we have dealt with the multivariate case of random variables of geometric type. We considered two independent samples of random variables of geometric types. Using a copula of extreme values, in particular the logistic copula, we proposed a joint limit distribution of two independent samples of subsequences of geometric type random variables. We then exposed the limited law which results from it then we called upon the copulas of the extreme values to propose a joint limited law for two independent samples of random variables of geometric type.","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"232 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80274848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-05DOI: 10.11648/J.ACM.20211006.11
L. Davis, F. Pahlevani, T. S. Rajan
The focus of this paper is the development, numerical simulation and parameter analysis of a model of the transcription of ribosomal RNA in highly transcribed genes. Inspired by the well-known classic Lighthill-Whitham-Richards (LWR) traffic flow model, a linear advection continuum model is used to describe the DNA transcription process. In this model, elongation velocity is assumed to be essentially constant as RNA polymerases move along the strand through different phases of gene transcription. One advantage of using the linear model is that it allows one to quantify how small perturbations in elongation velocity and inflow parameters affect important biology measures such as Average Transcription Time (ATT) for the gene. The ATT per polymerase is the amount of time an individual RNAP spends traveling through the DNA strand. The numerical treatment for model simulations includes introducing a low complexity and time accurate method by adding a simple linear time filter to the classic upwind scheme. This improved method is modular and requires a minimal modification of adding only one line of code resulting in increased accuracy without increased computational expense. In addition, it removes the overdamping of upwind. A stability condition for the new algorithm is derived, and numerical computations illustrate stability and convergence of the filtered scheme as well as improved ATT estimation.
{"title":"An Accurate and Stable Filtered Explicit Scheme for Biopolymerization Processes in the Presence of Perturbations","authors":"L. Davis, F. Pahlevani, T. S. Rajan","doi":"10.11648/J.ACM.20211006.11","DOIUrl":"https://doi.org/10.11648/J.ACM.20211006.11","url":null,"abstract":"The focus of this paper is the development, numerical simulation and parameter analysis of a model of the transcription of ribosomal RNA in highly transcribed genes. Inspired by the well-known classic Lighthill-Whitham-Richards (LWR) traffic flow model, a linear advection continuum model is used to describe the DNA transcription process. In this model, elongation velocity is assumed to be essentially constant as RNA polymerases move along the strand through different phases of gene transcription. One advantage of using the linear model is that it allows one to quantify how small perturbations in elongation velocity and inflow parameters affect important biology measures such as Average Transcription Time (ATT) for the gene. The ATT per polymerase is the amount of time an individual RNAP spends traveling through the DNA strand. The numerical treatment for model simulations includes introducing a low complexity and time accurate method by adding a simple linear time filter to the classic upwind scheme. This improved method is modular and requires a minimal modification of adding only one line of code resulting in increased accuracy without increased computational expense. In addition, it removes the overdamping of upwind. A stability condition for the new algorithm is derived, and numerical computations illustrate stability and convergence of the filtered scheme as well as improved ATT estimation.","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"17 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79474215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-16DOI: 10.11648/J.ACM.20211005.12
Liu Weili, Huimin Lu
Knot theory is a branch of the geometric topology, the core question of knot theory is to explore the equivalence classification of knots; In other words, for a knot, how to determine whether the knot is an unknot; giving two knots, how to determine whether the two knots are equivalent. To prove that two knots are equivalent, it is necessary to turn one knot into another through the same mark transformation, but to show that two knots are unequal, the problem is not as simple as people think. We cannot say that they are unequal because we can't see the deformation between them. For the equivalence classification problem of knots, we mainly find equivalent invariants between knots. Currently, scholars have also defined multiple knot invariants, but they also have certain limitations, and even more difficult to understand. In this paper, based on existing theoretical results, we define a knot invariant through the skein relation with two equations. To prove this knot invariant, we define a function f(L), and to prove f(L) to be a homology invariant of a non-directed link, we need to show that it remains constant under the Reideminster moves. This article first defines the fk(L), the property of f(L) is obtained by using the properties of fk(L). In the process of proof, the induction method has been used many times. The proof process is somewhat complicated, but it is easier to understand. And the common knot invariant is defined by one equation, which defining the knot invariant with two equations in this paper.
{"title":"A Knot Invariant Defined Based on the Skein Relation with Two Equations","authors":"Liu Weili, Huimin Lu","doi":"10.11648/J.ACM.20211005.12","DOIUrl":"https://doi.org/10.11648/J.ACM.20211005.12","url":null,"abstract":"Knot theory is a branch of the geometric topology, the core question of knot theory is to explore the equivalence classification of knots; In other words, for a knot, how to determine whether the knot is an unknot; giving two knots, how to determine whether the two knots are equivalent. To prove that two knots are equivalent, it is necessary to turn one knot into another through the same mark transformation, but to show that two knots are unequal, the problem is not as simple as people think. We cannot say that they are unequal because we can't see the deformation between them. For the equivalence classification problem of knots, we mainly find equivalent invariants between knots. Currently, scholars have also defined multiple knot invariants, but they also have certain limitations, and even more difficult to understand. In this paper, based on existing theoretical results, we define a knot invariant through the skein relation with two equations. To prove this knot invariant, we define a function f(L), and to prove f(L) to be a homology invariant of a non-directed link, we need to show that it remains constant under the Reideminster moves. This article first defines the fk(L), the property of f(L) is obtained by using the properties of fk(L). In the process of proof, the induction method has been used many times. The proof process is somewhat complicated, but it is easier to understand. And the common knot invariant is defined by one equation, which defining the knot invariant with two equations in this paper.","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"68 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2021-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88746875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-09DOI: 10.11648/J.ACM.20211004.12
Wajahat Ali, Zhipeng Qiu
HIV spreads by cell-to-cell transfer and the release of cell-free particles. A slightly more effective method of retroviral transmission is the direct cell-to-cell transfer of HIV, according to recent reports. Intracellular interaction between unhealthy and healthy cells, in combination with cytokine discharged by the cells included, may affect the susceptibility of a target resting CD4+T cell to HIV infection and the formation of latent infection. We suggest a class of HIV latency mathematical model, integrating both cell-free virus transmission and direct cell-to-cell diffusion to improve the understanding of the dynamics of the latent reservoirs. We incorporate four components in our model: the uninfected T cells, the latently infected T cells, the active-infected T cells and the HIV viruses. We examine the latency model by introducing the basic reproduction number. We first establish the non-negativity and boundedness of the solutions of the system, and then we investigate the global stability of the steady states. The diseased-free equilibrium is globally stable when the basic reproduction number is less than 1 and if the basic reproduction number is greater than 1, the diseased equilibrium exists and is globally stable. Numerical simulations are executed to interpret the theoretical outcomes and evaluate the relative contribution of latency fractions in the virus production and the HIV latent reservoir by providing estimates.
{"title":"The Global Dynamics of HIV Latency Model Including Cell-to-Cell Viral Transmission","authors":"Wajahat Ali, Zhipeng Qiu","doi":"10.11648/J.ACM.20211004.12","DOIUrl":"https://doi.org/10.11648/J.ACM.20211004.12","url":null,"abstract":"HIV spreads by cell-to-cell transfer and the release of cell-free particles. A slightly more effective method of retroviral transmission is the direct cell-to-cell transfer of HIV, according to recent reports. Intracellular interaction between unhealthy and healthy cells, in combination with cytokine discharged by the cells included, may affect the susceptibility of a target resting CD4+T cell to HIV infection and the formation of latent infection. We suggest a class of HIV latency mathematical model, integrating both cell-free virus transmission and direct cell-to-cell diffusion to improve the understanding of the dynamics of the latent reservoirs. We incorporate four components in our model: the uninfected T cells, the latently infected T cells, the active-infected T cells and the HIV viruses. We examine the latency model by introducing the basic reproduction number. We first establish the non-negativity and boundedness of the solutions of the system, and then we investigate the global stability of the steady states. The diseased-free equilibrium is globally stable when the basic reproduction number is less than 1 and if the basic reproduction number is greater than 1, the diseased equilibrium exists and is globally stable. Numerical simulations are executed to interpret the theoretical outcomes and evaluate the relative contribution of latency fractions in the virus production and the HIV latent reservoir by providing estimates.","PeriodicalId":55503,"journal":{"name":"Applied and Computational Mathematics","volume":"7 1","pages":""},"PeriodicalIF":10.0,"publicationDate":"2021-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85819239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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