Pub Date : 2006-01-01DOI: 10.1027/0838-1925.18.2.46
J. Ring
{"title":"Allergy, After 100 Years Still an Increasingly Exciting Field","authors":"J. Ring","doi":"10.1027/0838-1925.18.2.46","DOIUrl":"https://doi.org/10.1027/0838-1925.18.2.46","url":null,"abstract":"","PeriodicalId":55539,"journal":{"name":"Allergy & Clinical Immunology International","volume":"49 1","pages":"46-46"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90588802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2006-01-01DOI: 10.1027/0838-1925.18.1.1
M. Kaliner
{"title":"A New Direction for WAO and ACII – J WAO","authors":"M. Kaliner","doi":"10.1027/0838-1925.18.1.1","DOIUrl":"https://doi.org/10.1027/0838-1925.18.1.1","url":null,"abstract":"","PeriodicalId":55539,"journal":{"name":"Allergy & Clinical Immunology International","volume":"1 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90784970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2006-01-01DOI: 10.1027/0838-1925.18.5.203
S. Mukhopadhyay, A. Mitra, A. Crighton, S. Ogston
{"title":"Raised Lung Volumes and Fixed Airflow Limitation in Children with Asthma","authors":"S. Mukhopadhyay, A. Mitra, A. Crighton, S. Ogston","doi":"10.1027/0838-1925.18.5.203","DOIUrl":"https://doi.org/10.1027/0838-1925.18.5.203","url":null,"abstract":"","PeriodicalId":55539,"journal":{"name":"Allergy & Clinical Immunology International","volume":"40 1","pages":"203-206"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82932910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2006-01-01DOI: 10.1027/0838-1925.18.1.11
M. Gold
{"title":"Prevention and Management of Anaphylaxis in Schools - The Challenge of Policy and Practice","authors":"M. Gold","doi":"10.1027/0838-1925.18.1.11","DOIUrl":"https://doi.org/10.1027/0838-1925.18.1.11","url":null,"abstract":"","PeriodicalId":55539,"journal":{"name":"Allergy & Clinical Immunology International","volume":"90 1","pages":"11-14"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75681159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2006-01-01DOI: 10.1027/0838-1925.18.2.65
B. Hales, Nora Chu, A. Bosco, W. Smith, Tatjana K Heinrich, W. Thomas
Results: The studies summarized here show that quantitative measurements of allergen panels provide a better assessment of total anti-mite IgE than assays with mite extracts, and that major allergen Der p 1 induced correspondingly higher T helper cell type 2 (Th2) and Th1 cytokine responses than subordinate allergens Der p 5 and 7. The importance of the knowledge of variants of the major allergens is presented as well recent advances in the characterization of the molecules. Conclusions: Der p 1 and Der p 2 are major allergens of Dermatophagoides pteronyssinus. The minor allergens, however, constitute 50% of the IgE binding and the use of a panel of allergens provides a better measure of house dust mite allergy than IgE binding to extracts. The minor allergens will also be important for studying the immunoregulatory pathways that lead to high and low allergenicity.
结果:本文总结的研究表明，与螨提取物相比，过敏原组的定量测量可以更好地评估抗螨总IgE，并且主要过敏原Der p1诱导的T辅助细胞2型(Th2)和Th1细胞因子反应相应高于次要过敏原Der p1 5和7。介绍了主要过敏原变异知识的重要性以及分子表征的最新进展。结论:Der p 1和Der p 2是蝶窦类皮噬菌的主要变应原。然而，次要的过敏原占IgE结合的50%，使用一组过敏原比IgE结合提取物提供了更好的测量屋尘螨过敏的方法。次要过敏原对于研究导致高和低过敏原的免疫调节途径也很重要。
{"title":"Determinants of house dust mite allergenicity","authors":"B. Hales, Nora Chu, A. Bosco, W. Smith, Tatjana K Heinrich, W. Thomas","doi":"10.1027/0838-1925.18.2.65","DOIUrl":"https://doi.org/10.1027/0838-1925.18.2.65","url":null,"abstract":"Results: The studies summarized here show that quantitative measurements of allergen panels provide a better assessment of total anti-mite IgE than assays with mite extracts, and that major allergen Der p 1 induced correspondingly higher T helper cell type 2 (Th2) and Th1 cytokine responses than subordinate allergens Der p 5 and 7. The importance of the knowledge of variants of the major allergens is presented as well recent advances in the characterization of the molecules. Conclusions: Der p 1 and Der p 2 are major allergens of Dermatophagoides pteronyssinus. The minor allergens, however, constitute 50% of the IgE binding and the use of a panel of allergens provides a better measure of house dust mite allergy than IgE binding to extracts. The minor allergens will also be important for studying the immunoregulatory pathways that lead to high and low allergenicity.","PeriodicalId":55539,"journal":{"name":"Allergy & Clinical Immunology International","volume":"11 1","pages":"65-70"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74878715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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