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ASSESSMENT OF ISOMETRIC AND ISOKINETIC ANKLE STRENGTH MEASURES: A PILOT STUDY. 评估等长和等速踝关节力量测量:一项初步研究。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e288925
Carolina Lins, Andreza Ribeiro Batista DE Oliveira, Marina Squarizi Simões Chagas, Felippe Ribeiro, Alberto Cliquet, Rodrigo Gonçalves Pagnano

Objective: To evaluate isometric and isokinetic ankle strength in of dorsiflexion (DF), plantar flexion (PF), inversion (INV), and eversion (EVE) in healthy individuals.

Methods: A cross-sectional study was conducted with individuals aged 18 to 60 years, of both sexes. The Lafayette® isometric manual dynamometer was used to evaluate isometric strength, the Humac Norm® isokinetic dynamometer to evaluate isokinetic strength, and the IPAQ questionnaire (International Physical Activity Questionnaire) for the level of physical activity. Statistical analysis compared sex, dominance, and physical activity level with isometric and isokinetic strengths using the Spearman coefficient and the Mann-Whitney test.

Results: There was a difference between genders for dominant and non-dominant limbs in isokinetic strength and not in isometric strength. There was a difference between isokinetic strength variables and physical activity levels. The isokinetic strength of dominant PF (p=0.0153), non-dominant (p=0.0287), and non-dominant INV (p=0.0183) demonstrated that very active individuals have a higher torque peak than irregularly active and sedentary individuals.

Conclusion: The results demonstrated greater isokinetic strength in men than in women and active individuals compared to sedentary ones. However, it was not possible to establish an association between isometric and isokinetic ankle measurements. Level of Evidence IV, Cross-Sectional Study.

目的:评价健康人群背屈(DF)、足底屈(PF)、内翻(INV)和外翻(EVE)的等长和等速踝关节力量。方法:对年龄在18 - 60岁的男女进行横断面研究。采用拉斐特(Lafayette)等速手动测力仪评估等速强度,采用Humac Norm®等速测力仪评估等速强度,采用IPAQ问卷(国际体力活动问卷)评估体力活动水平。统计分析使用Spearman系数和Mann-Whitney检验比较性别、优势和体力活动水平与等长和等速力量。结果:优势肢体和非优势肢体在等速力量上存在性别差异,而在等速力量上无性别差异。等速力量变量和体力活动水平之间存在差异。显性PF (p=0.0153)、非显性INV (p=0.0287)和非显性INV (p=0.0183)的等速强度表明,非常活跃的个体比不规律运动和久坐的个体具有更高的扭矩峰值。结论:结果表明,男性的等速运动强度高于女性,活跃的人比久坐的人更强。然而,不可能在等长和等速踝关节测量之间建立联系。证据水平IV,横断面研究。
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引用次数: 0
REINFORCEMENT WITH THE LONG HEAD OF THE BICEPS TENDON IN LARGE AND MASSIVE REPAIRABLE ROTATOR CUFF TEARS: A PROSPECTIVE CASE SERIES. 肱二头肌肌腱长头加固大面积可修复的肩袖撕裂:前瞻性病例系列。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e288796
Gustavo DE Mello Ribeiro Pinto, Cristiano Nabuco Dantas, Marcelo Costa DE Oliveira Campos, Jorge Henrique Assunção, Mauro Emilio Conforto Gracitelli, Eduardo Angeli Malavolta

Introduction: The treatment of large and massive rotator cuff tears remains challenging. This study evaluates the efficacy and safety of reinforcement with the long head of the biceps tendon (LHBT) in patients with large and massive repairable rotator cuff tears.

Methods: This is a prospective case series involving 25 patients who underwent open repair of large and massive rotator cuff tears with LHBT reinforcement. All patients were operated by the same surgeon and followed up for one year.

Results: Pain scores (VAS: 6.6 ± 2.30 vs. 2.68 ± 2.73; p<0.001) and function scores (ASES: 36.86 ± 19.27 vs. 73.96 ± 23.73; p<0.001; UCLA: 13.04 ± 3.83 vs. 26.04 ± 7.39; p<0.001) improved significantly postoperatively compared to preoperatively. The biceps healing rate was 84%, while the rotator cuff retear rate was 60%. No complications related to the biceps or surgical site infections were documented.

Conclusion: Reinforcement with the long head of the biceps tendon in the repair of large and massive rotator cuff tears shows satisfactory clinical outcomes and a low complication rate. Level of Evidence: IV, Case Series.

简介:大而大量的肩袖撕裂的治疗仍然具有挑战性。本研究评估了肱二头肌肌腱长头(LHBT)加固治疗大面积可修复的肩袖撕裂的疗效和安全性。方法:这是一个前瞻性的病例系列,涉及25例患者,他们接受了大而大块的肩袖撕裂开放修复与LHBT加固。所有患者均由同一位外科医生手术,随访1年。结果:疼痛评分(VAS: 6.6±2.30 vs. 2.68±2.73)结论:肱二头肌肌腱长头加固修复大、块状肩袖撕裂,临床效果满意,并发症发生率低。证据等级:IV,案例系列。
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引用次数: 0
SPONTANEOUS RUPTURE OF BAKER'S CYST - CASE SERIES. 贝克氏囊肿系列的自发性破裂。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e290230
Gilberto Luis Camanho, Riccardo Gomes Gobbi, Márcia Uchôa DE Rezende, Guilherme Pereira Ocampos

Objective: The presence of popliteal cysts is common, although often unkown to the patient. When spontaneous rupture occurs, the clinical presentation is typically dramatic, frequently prompting the patient to seek emergency care. Eventually the condition can be mistaken for other pathologies, more commonly deep vein thrombosis, leading to inappropriate treatment. The objective of this study is to describe a case series of spontaneous Baker's cyst ruptures, with a 2-year follow-up.

Methods: Sixteen consecutive patients with symptomatic ruptured popliteal cyst were treated acutely with anti-inflammatory measures and physical therapy.

Results: All patients had a good resolution of their cases with conservative treatment over an average period of one week, and there was no recurrence of cyst rupture.

Conclusion: Spontaneous rupture of Baker's cyst in adult patients can be very symptomatic and disabling; however, once diagnosed, it responds well to conservative treatment and rarely recurs. Level of Evidence IV; Case Series.

目的:腘窝囊肿的存在是常见的,尽管通常不为患者所知。当自发破裂发生时,临床表现通常是戏剧性的,经常促使患者寻求紧急护理。最终,这种情况可能被误认为是其他病理,更常见的是深静脉血栓,导致不适当的治疗。本研究的目的是描述一个自发性贝克氏囊肿破裂的病例系列,随访2年。方法:对16例有症状的腘窝囊肿急性破裂患者进行抗炎治疗和物理治疗。结果:所有患者经保守治疗平均1周,病情得到良好缓解,无囊肿破裂复发。结论:成人贝克囊肿自发性破裂可引起严重的症状和致残;然而,一旦确诊,它对保守治疗反应良好,很少复发。证据水平IV;系列。
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引用次数: 0
PROFILE AND LEARNING CURVE OF BRAZILIAN SURGEONS REGARDING SHOULDER ARTHROSCOPY. 巴西外科医生肩关节镜检查的概况和学习曲线。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e288584
Guilherme Vieira Lima, Paulo Santoro Belangero, Renato Aroca Zan, Rafael Fuchs Lazarini, Bernardo Barcellos Terra, Marcelo Carvalho Krause Goncalves, Maria Isabel Pozzi Guerra, Lucas Braga Jacques Gonçalves, Marcio Diego Castro Teixeira, Sandro DA Silva Reginaldo, Luis Alfredo Gomez-Vieira

Objective: The aim of this study is to investigate the number of surgeries necessary for an orthopedic surgeon specialized in shoulder surgery to become proficient in performing arthroscopy. This is an original article with level V evidence.

Methods: A cross-sectional study was designed to examine the perspectives of surgeons at various stages of their careers, using an online questionnaire.

Results: A total of 251 participants responded. The most prevalent training period was more than 15 years of experience. The proficient level was the most prevalent. In evaluating the number of arthroscopies by proficiency level, all agreed that for the specialist level, a total of over 500 arthroscopies is necessary. Most respondents judged 31 to 50 arthroscopies as necessary to perform safely. According to the methodologies, the best-rated were acting as the lead surgeon and training on cadavers.

Conclusion: The study showed that 31 to 50 cases are necessary to perform shoulder arthroscopy safely, and over 500 cases to reach the specialist level. Participation as the lead surgeon and training on cadavers were rated as very important in specialist training. Evidence Level V; Expert Opinion.

目的:本研究的目的是调查肩部外科整形外科医生熟练进行关节镜手术所需的手术次数。这是一篇有V级证据的原创文章。方法:采用一份在线问卷,设计了一项横断面研究,以检查外科医生在其职业生涯的不同阶段的观点。结果:共有251名参与者回应。最普遍的培训期是15年以上的经验。熟练水平是最普遍的。在按熟练程度评估关节镜检查次数时,所有人都同意,对于专科水平,总共需要超过500次关节镜检查。大多数应答者认为31到50次关节镜检查是安全的。根据方法论,评分最高的是担任首席外科医生和接受尸体培训。结论:本研究表明,需要31 ~ 50例患者才能安全完成肩关节镜手术,500例以上患者才能达到专科水平。作为首席外科医生的参与和尸体培训在专科培训中被认为是非常重要的。证据等级V;专家的意见。
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引用次数: 0
APPLICATION OF ANTERIOR MINI-INCISION VERTEBROPLASTY IN CERVICAL METASTASES. 前路小切口椎体成形术在颈椎转移瘤中的应用。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e288709
Guan Shi, Hao Chen, P U Jia, L I Bao, Fei Feng

Objective: To investigate the efficacy and safety of anterior cervical mini-incision vertebroplasty in the treatment of vertebral metastases.

Methods: From July 2009 to March 2013, seven cases of vertebral metastases were treated by using vertebroplasty through an anterior cervical paratracheal mini-incision guided by C-arm X-ray in Beijing friendship hospital, Capital medical university. Among them, three were male and four were female, aged 51 to 74 years with an average age of 61.7 years. Preoperative and postoperative Visual Analog Scale (VAS) scores and analgesic medication usage were evaluated, and postoperative pain relief was assessed using the World Health Organization (WHO) criteria.

Results: All seven surgeries were successful without any occurrences of complications such as nerve or vascular injury, pulmonary embolism, or hematoma. The average cement injection volume was 1.8ml, and postoperative X-rays and CT scans indicated satisfactory cement filling, with two cases showing paravertebral cement leakage, but without clinical symptoms. One week postoperatively, the VAS score decreased from a preoperative average of 8.86 to 2.14, with complete pain relief in three cases, leading to the cessation of analgesic drugs, and partial pain relief in four cases, resulting in a reduction or downgrade of analgesic medications. Follow-ups ranged from 3 to 28 months, with one patient dying at 3 months postoperatively, one at 4 months, two at 6 months, one at 8 months, and one at 17 months, while one patient survived 28 months postoperatively. Postoperatively, all patients showed no worsening of local pain symptoms, and the surgical efficacy remained stable.

Conclusion: Anterior cervical mini-incision vertebroplasty is a precise and effective method for pain relief in the treatment of vertebral metastases, providing a safe approach that reduces the risk of damaging critical cervical tissues during the puncture procedure and postoperative hematoma formation. Level of Evidence lll; Retrospective Study.

目的:探讨颈椎前路小切口椎体成形术治疗椎体转移瘤的疗效和安全性。方法:2009年7月至2013年3月,在首都医科大学附属北京友谊医院c臂x线引导下经颈椎前路气管旁小切口椎体成形术治疗7例椎体转移瘤。其中男3名,女4名,年龄51至74岁,平均年龄61.7岁。评估术前和术后视觉模拟量表(VAS)评分和镇痛药物使用情况,并根据世界卫生组织(WHO)标准评估术后疼痛缓解情况。结果:7例手术均成功,无神经、血管损伤、肺栓塞、血肿等并发症发生。平均骨水泥注射量1.8ml,术后x线及CT扫描显示骨水泥充填满意,2例椎旁骨水泥渗漏,无临床症状。术后1周,VAS评分由术前平均8.86分下降至2.14分,3例患者疼痛完全缓解,导致停止使用镇痛药物,4例患者疼痛部分缓解,导致镇痛药物减少或降级。随访时间为3 ~ 28个月,术后3个月死亡1例,4个月死亡1例,6个月死亡2例,8个月死亡1例,17个月死亡1例,术后28个月存活1例。术后所有患者均无局部疼痛症状加重,手术疗效稳定。结论:颈椎前路小切口椎体成形术是一种精确有效的治疗椎体转移疼痛的方法,提供了一种安全的方法,降低了穿刺过程中颈椎关键组织损伤和术后血肿形成的风险。《证据水平》;回顾性研究。
{"title":"APPLICATION OF ANTERIOR MINI-INCISION VERTEBROPLASTY IN CERVICAL METASTASES.","authors":"Guan Shi, Hao Chen, P U Jia, L I Bao, Fei Feng","doi":"10.1590/1413-785220253302e288709","DOIUrl":"10.1590/1413-785220253302e288709","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the efficacy and safety of anterior cervical mini-incision vertebroplasty in the treatment of vertebral metastases.</p><p><strong>Methods: </strong>From July 2009 to March 2013, seven cases of vertebral metastases were treated by using vertebroplasty through an anterior cervical paratracheal mini-incision guided by C-arm X-ray in Beijing friendship hospital, Capital medical university. Among them, three were male and four were female, aged 51 to 74 years with an average age of 61.7 years. Preoperative and postoperative Visual Analog Scale (VAS) scores and analgesic medication usage were evaluated, and postoperative pain relief was assessed using the World Health Organization (WHO) criteria.</p><p><strong>Results: </strong>All seven surgeries were successful without any occurrences of complications such as nerve or vascular injury, pulmonary embolism, or hematoma. The average cement injection volume was 1.8ml, and postoperative X-rays and CT scans indicated satisfactory cement filling, with two cases showing paravertebral cement leakage, but without clinical symptoms. One week postoperatively, the VAS score decreased from a preoperative average of 8.86 to 2.14, with complete pain relief in three cases, leading to the cessation of analgesic drugs, and partial pain relief in four cases, resulting in a reduction or downgrade of analgesic medications. Follow-ups ranged from 3 to 28 months, with one patient dying at 3 months postoperatively, one at 4 months, two at 6 months, one at 8 months, and one at 17 months, while one patient survived 28 months postoperatively. Postoperatively, all patients showed no worsening of local pain symptoms, and the surgical efficacy remained stable.</p><p><strong>Conclusion: </strong>Anterior cervical mini-incision vertebroplasty is a precise and effective method for pain relief in the treatment of vertebral metastases, providing a safe approach that reduces the risk of damaging critical cervical tissues during the puncture procedure and postoperative hematoma formation. Level of Evidence lll; Retrospective Study.</p>","PeriodicalId":55563,"journal":{"name":"Acta Ortopedica Brasileira","volume":"33 spe2","pages":"e288709"},"PeriodicalIF":0.6,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OUTCOMES OF EARLY SURGICAL REPAIR OF THE KNEE EXTENSOR MECHANISM INJURY, COMPARING THE QUADRICEPS AND PATELLAR TENDON INJURIES: A PROSPECTIVE OBSERVATIONAL STUDY. 早期手术修复膝关节伸肌机制损伤的结果,比较股四头肌和髌骨肌腱损伤:一项前瞻性观察研究。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e290211
Vinícius Antônio Santos Aragão, João Victor Lacerda Belfort, Flavio DE Fava Sanches, Renan José Rigonato, Maria Adelaide DE Miranda Gonçalves, Marcos DE Camargo Leonhardt, Jorge Dos Santos Silva, Kodi Edson Kojima

Objectives: this study aimed to compare the radiographic, functional and isokinetic results of the early repair of quadriceps tendon rupture (QTR) and patellar tendon rupture (PTR).

Methods: We conducted a prospective observational study at a level one urban university trauma center from January 2022 to March 2023. The study included patients aged 18 years and older who underwent surgery within three weeks of injury and had at least one year of follow-up. The evaluation used the patellar indices (Insall-Salvati, Blackburn Peel and Caton Deschamps), functional (Lysholm and PCS-12) and isokinetic assessment.

Results: the study involved 20 patients, predominantly male, with a slight predominance of left-sided injuries. The mean age was 39.4 years. Surgical outcomes showed no significant radiographic differences post-repair. Functionally, the PTR group exhibited better recovery compared to the QTR group, particularly in returning to sports and work. Isokinetic testing revealed a substantial reduction in strength on the injured side compared to the uninjured side across both groups.

Conclusion: early surgical intervention leads to favorable radiographic and functional outcomes. The PTR group showed better functional recovery, especially in return to work and sports. No significant differences were found in isokinetic strength recovery between the QTR and PTR groups. Level of Evidence III; Prospective Observational Study.

目的:本研究旨在比较股四头肌肌腱断裂(QTR)和髌骨肌腱断裂(PTR)早期修复的影像学、功能和等速结果。方法:于2022年1月至2023年3月在某城市高校一级创伤中心进行前瞻性观察研究。该研究包括年龄在18岁及以上的患者,他们在受伤后三周内接受了手术,并进行了至少一年的随访。评估采用髌骨指数(Insall-Salvati、Blackburn Peel和Caton Deschamps)、功能(Lysholm和PCS-12)和等动力学评估。结果:本研究涉及20例患者,以男性为主,左侧损伤略占优势。平均年龄39.4岁。修复后的手术结果无明显的影像学差异。功能上,PTR组比QTR组表现出更好的恢复,特别是在恢复运动和工作方面。等速测试显示,与未受伤的一侧相比,两组受伤侧的力量都有明显的减少。结论:早期手术干预可获得良好的影像学和功能预后。PTR组表现出更好的功能恢复,特别是重返工作和运动。QTR组和PTR组在等速力量恢复方面无显著差异。证据等级III;前瞻性观察研究。
{"title":"OUTCOMES OF EARLY SURGICAL REPAIR OF THE KNEE EXTENSOR MECHANISM INJURY, COMPARING THE QUADRICEPS AND PATELLAR TENDON INJURIES: A PROSPECTIVE OBSERVATIONAL STUDY.","authors":"Vinícius Antônio Santos Aragão, João Victor Lacerda Belfort, Flavio DE Fava Sanches, Renan José Rigonato, Maria Adelaide DE Miranda Gonçalves, Marcos DE Camargo Leonhardt, Jorge Dos Santos Silva, Kodi Edson Kojima","doi":"10.1590/1413-785220253302e290211","DOIUrl":"10.1590/1413-785220253302e290211","url":null,"abstract":"<p><strong>Objectives: </strong>this study aimed to compare the radiographic, functional and isokinetic results of the early repair of quadriceps tendon rupture (QTR) and patellar tendon rupture (PTR).</p><p><strong>Methods: </strong>We conducted a prospective observational study at a level one urban university trauma center from January 2022 to March 2023. The study included patients aged 18 years and older who underwent surgery within three weeks of injury and had at least one year of follow-up. The evaluation used the patellar indices (Insall-Salvati, Blackburn Peel and Caton Deschamps), functional (Lysholm and PCS-12) and isokinetic assessment.</p><p><strong>Results: </strong>the study involved 20 patients, predominantly male, with a slight predominance of left-sided injuries. The mean age was 39.4 years. Surgical outcomes showed no significant radiographic differences post-repair. Functionally, the PTR group exhibited better recovery compared to the QTR group, particularly in returning to sports and work. Isokinetic testing revealed a substantial reduction in strength on the injured side compared to the uninjured side across both groups.</p><p><strong>Conclusion: </strong>early surgical intervention leads to favorable radiographic and functional outcomes. The PTR group showed better functional recovery, especially in return to work and sports. No significant differences were found in isokinetic strength recovery between the QTR and PTR groups. Level of Evidence III; Prospective Observational Study.</p>","PeriodicalId":55563,"journal":{"name":"Acta Ortopedica Brasileira","volume":"33 spe2","pages":"e290211"},"PeriodicalIF":0.6,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ROLE OF POLYMORPHISMS IN VEGF AND KDR GENES IN OSTEOSARCOMA SUSCEPTIBILITY: A SYSTEMATIC REVIEW. vegf和KDR基因多态性在骨肉瘤易感性中的作用:一项系统综述。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e291664
Amanda Dos Santos Cavalcanti, Jéssica Vilarinho Cardoso, Verônica Aran Ponte, Jade Pires Nascimento, Mariana Chantre-Justino, Ana Cristina DE Sá Lopes, Walter Meohas, Jamila Alessandra Perini

Osteosarcoma is the most common aggressive primary bone tumor in children and adolescents. Angiogenesis, induced by vascular endothelial growth factor (VEGF) and its receptor (kinase insert domain receptor - KDR) is involved in tumor development. Both genes (VEGF and KDR) are polymorphic, and their association with osteosarcoma remains unclear. A systematic review of observational studies was performed to evaluate the association between polymorphisms in these genes and osteosarcoma development. Pubmed, Medline, Lilacs, and Scielo databases were searched for observational studies published up to April 2024. Eight publications of case-control studies were included, with quality ranging from 82% to 95%. All subjects were from the Chinese population: 1,681 cases and 2,049 controls. A total of six VEGF polymorphisms were analyzed. For osteosarcoma susceptibility, three studies found an increased risk with VEGF rs699947, four with VEGF rs2010963, two with VEGF rs3025039, one with VEGF rs833061, and no studies found an association with the VEGF rs1570360 and VEGF rs10434 SNPs. In addition, no studies evaluated SNPs in the KDR gene and osteosarcoma susceptibility. Further studies in diverse populations, particularly in Brazil, are necessary to clarify the role of VEGF and KDR polymorphisms in osteosarcoma development and prognosis. Level of evidence III; Systematic Review.

骨肉瘤是儿童和青少年中最常见的侵袭性原发性骨肿瘤。血管新生是由血管内皮生长因子(VEGF)及其受体(激酶插入结构域受体- KDR)诱导的。这两个基因(VEGF和KDR)都是多态的,它们与骨肉瘤的关系尚不清楚。对观察性研究进行了系统回顾,以评估这些基因多态性与骨肉瘤发展之间的关系。检索Pubmed、Medline、Lilacs和Scielo数据库,检索截至2024年4月发表的观察性研究。纳入了8篇病例对照研究的出版物,质量从82%到95%不等。所有受试者均来自中国人群:1681例和2049例对照。共分析了6个VEGF多态性。对于骨肉瘤易感性,3项研究发现VEGF rs699947、4项研究发现VEGF rs2010963、2项研究发现VEGF rs3025039、1项研究发现VEGF rs833061与骨肉瘤易感性相关,没有研究发现VEGF rs1570360和VEGF rs10434 snp与骨肉瘤易感性相关。此外,没有研究评估KDR基因snp与骨肉瘤易感性的关系。有必要在不同人群中,特别是在巴西进行进一步的研究,以阐明VEGF和KDR多态性在骨肉瘤发展和预后中的作用。证据等级III;系统的回顾。
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引用次数: 0
TREATMENT OF LATERAL EPICONDYLITIS OF THE ELBOW WITH HYALURONIC ACID INJECTIONS. 透明质酸注射治疗肘关节外上髁炎。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e289985
Mauro Emilio Conforto Gracitelli, Luiza DE Campos Moreira DA Silva, Jorge Henrique Assunção, Fernando Brandão DE Andrade E Silva, Arnaldo Amado Ferreira, Eduardo Angeli Malavolta

Introduction: The primary objective was to evaluate the efficacy of hyaluronic acid injections for lateral epicondylitis. Secondary objectives included assessing pain and functional outcomes at various time points following the injection.

Methods: This prospective cohort study included patients who received two hyaluronic acid injections one week apart after prior conservative treatment. Assessments were conducted at two and six weeks, and at three, six, and 12 months post-injection. Outcome measures were pain scores (Visual Analogue Scale), functional assessment (Single Assessment Numeric Evaluation), and injection site complications.

Results: A total of 46 patients (52 elbows) were included. Significant improvements were observed in pain scores measured by VAS at rest, from 4.5±2.8 initially to 2.7±2.8 at 3 months and 2.3±3.0 at 12 months (p<0.001). Similar improvements were seen in VAS scores during maximum hand grip strength, from 5.8±3.1 initially to 2.8±3.4 at 12 months (p<0.001). SANE score also improved significantly. No complications were reported.

Conclusions: Treatment of lateral epicondylitis with hyaluronic acid showed statistically significant improvement in VAS scores at rest and during maximum hand grip strength, as well as in SANE scores, with no reported complications. Level of Evidence IV; Case Series.

简介:主要目的是评估透明质酸注射治疗外侧上髁炎的疗效。次要目标包括评估注射后不同时间点的疼痛和功能结果。方法:这项前瞻性队列研究纳入了在先前的保守治疗后间隔一周接受两次透明质酸注射的患者。在注射后2周、6周、3个月、6个月和12个月进行评估。结果测量是疼痛评分(视觉模拟量表)、功能评估(单一评估数字评估)和注射部位并发症。结果:共纳入46例患者(52个肘部)。观察到休息时VAS测量的疼痛评分有显著改善,从最初的4.5±2.8到3个月时的2.7±2.8和12个月时的2.3±3.0(结论:透明质酸治疗外侧上髁炎在休息时和最大握力时的VAS评分以及SANE评分有统计学意义上的显著改善,无并发症报道。证据水平IV;系列。
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引用次数: 0
IMPACT AND HEALTHCARE UTILIZATION PATTERNS OF AN ORTHOPEDIC TELEMEDICINE PROGRAM IN BRAZIL. 巴西骨科远程医疗项目的影响和医疗保健利用模式。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e292544
Fabio Seiji Mazzi Yamaguchi, Vitor Matheus Silva, Hector Fugihara Kroes, Jorge Dos Santos Silva, Raphael Martus Marcon, Henrique Melo DE Campos Gurgel

Objective: To examine the relationship between place of residence, social vulnerability, and telemedicine access among orthopedic patients at a tertiary hospital in São Paulo, Brazil.

Methods: A cross-sectional, comparative study analyzing sociodemographic, economic, and geographic characteristics of 475 patients who attended telemedicine consultations between August 2022 and August 2023. Patients were grouped by their Social Vulnerability Index (IVS) to assess differences in travel distances, costs, and accessibility challenges. The analysis included comparisons of demographic factors, financial burdens, and telemedicine's impact on reducing travel constraints.

Results: Telemedicine consultations avoided an average travel distance of 211 km and saved approximately 44 USD per consultation. Patients from higher IVS regions had significantly greater travel distances, longer travel times, lower formal education levels, and were more likely to be younger, male, and of non-White race. Additionally, these patients more frequently reported missing work for in-person visits. Telemedicine access disparities reflect broader socioeconomic and geographic inequalities.

Conclusions: This study highlights how spatial and socioeconomic vulnerabilities shape telemedicine access in Brazil. Travel burdens and job insecurity disproportionately affect vulnerable groups, while social support mitigates barriers for older adults. Level of Evidence III; Cross-Sectional Study.

目的:研究巴西圣保罗一家三级医院骨科患者的居住地、社会脆弱性和远程医疗可及性之间的关系。方法:采用横断面比较研究,分析2022年8月至2023年8月期间参加远程医疗咨询的475例患者的社会人口、经济和地理特征。根据患者的社会脆弱性指数(IVS)对患者进行分组,以评估旅行距离、费用和无障碍挑战的差异。分析包括人口因素、财政负担和远程医疗对减少旅行限制的影响的比较。结果:远程医疗会诊平均节省出行距离211公里,每次会诊节省约44美元。来自IVS较高地区的患者明显有较大的旅行距离,较长的旅行时间,较低的正规教育水平,并且更可能是年轻,男性和非白种人。此外,这些患者更频繁地报告错过了亲自访问的工作。远程医疗获取的差异反映了更广泛的社会经济和地理不平等。结论:本研究强调了空间和社会经济脆弱性如何影响巴西的远程医疗获取。旅行负担和工作不安全感对弱势群体的影响尤为严重,而社会支持则减轻了老年人的障碍。证据等级III;横断面研究。
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引用次数: 0
SURGICAL PROCEDURES PROLONG AMBULATION IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY. 外科手术延长杜氏肌营养不良患者的活动时间。
IF 0.6 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-10-13 eCollection Date: 2025-09-01 DOI: 10.1590/1413-785220253302e287732
David Gonçalves Nordon, Felipe Cruz Caetano Dos Reis, Carlos Alberto Dos Santos, Adilson DE Paula, Maria Bernadete Dutra DE Resende, Patricia Moreno Grangeiro

Objective: The aim of this study was to evaluate the effect of surgical procedures on maintaining ambulation for Duchenne patients.

Methods: This retrospective cohort study evaluated 35 patients for whom surgery was recommended at our institution from 2012 to 2020.

Results: Twenty-seven patients were operated on before gait loss, and eight after. In this study, surgical treatment allowed recovery and prolongation of gait for 38.6 months, on average. The sooner the surgery was performed, the better the results were; logistic regression analysis showed that each day of delay after gait loss decreased the chances of success by 0.2%. The optimal interval for intervention was up to 12 months after gait loss.

Conclusion: Our results thus corroborate the evidence that surgical interventions are beneficial for these patients and suggest a not previously described time window for achieving better outcomes. Level of Evidence lll; Retrospective, Comparative Study of Surgical Interventions.

目的:本研究的目的是评估外科手术对杜氏症患者维持活动的影响。方法:本回顾性队列研究评估了2012年至2020年在我院推荐手术的35例患者。结果:失步前手术27例,失步后手术8例。在这项研究中,手术治疗使步态恢复和延长平均38.6个月。手术越早进行,效果越好;逻辑回归分析显示,步态丧失后每延迟一天,成功的机会降低0.2%。干预的最佳时间间隔为步态丧失后12个月。结论:因此,我们的研究结果证实了手术干预对这些患者有益的证据,并提出了一个以前没有描述的时间窗口来获得更好的结果。《证据水平》;手术干预的回顾性比较研究。
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Acta Ortopedica Brasileira
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