首页 > 最新文献

Cancer Genetics and Cytogenetics最新文献

英文 中文
Expression of chemokine receptor CXCR3, CXCR4, and CXCR7 and their respective ligands in rhabdomyosarcoma 趋化因子受体CXCR3、CXCR4、CXCR7及其配体在横纹肌肉瘤中的表达
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.080
Teresa San Miguel , Robert Callaghan , Sandra Pinto , Alicia Martínez , Concha López-Ginés , Ana Pellín-Carcelén , Carmen Carda , Miguel Cerdá-Nicolás , Antonio Llombart-Bosch , Rosario Gil-Benso
{"title":"Expression of chemokine receptor CXCR3, CXCR4, and CXCR7 and their respective ligands in rhabdomyosarcoma","authors":"Teresa San Miguel , Robert Callaghan , Sandra Pinto , Alicia Martínez , Concha López-Ginés , Ana Pellín-Carcelén , Carmen Carda , Miguel Cerdá-Nicolás , Antonio Llombart-Bosch , Rosario Gil-Benso","doi":"10.1016/j.cancergencyto.2010.07.080","DOIUrl":"https://doi.org/10.1016/j.cancergencyto.2010.07.080","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 81"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.080","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136775582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Somatic mutations of signaling genes in non-small-cell lung cancer 非小细胞肺癌中信号基因的体细胞突变
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.134
Heather R. Sanders, Maher Albitar

Lung cancer is the leading cause of cancer-related deaths, with non-small-cell lung cancer (NSCLC) accounting for approximately 85% of cases. A significant proportion of NSCLC cases are not diagnosed until a late stage, when aggressive treatments are required but often prolong survival only modestly. Recent advances in molecular characterization of NSCLC have enabled identification of numerous cell growth and proliferation pathways that are disrupted in these tumors. This knowledge has provided insight into the mechanisms of tumor development in various histologic subtypes of NSCLC and has pointed the way toward targeted treatment strategies. In this review, we highlight literature findings of somatic mutations in genes involved in cell growth and proliferation that are commonly found in the various subtypes of NSCLC, and we discuss how these findings may relate to treatment strategies.

肺癌是癌症相关死亡的主要原因，非小细胞肺癌(NSCLC)约占85%。很大比例的非小细胞肺癌病例直到晚期才被诊断出来，这时需要积极的治疗，但往往只能适度地延长生存期。NSCLC分子特征的最新进展使我们能够识别在这些肿瘤中被破坏的许多细胞生长和增殖途径。这些知识为了解不同组织学亚型非小细胞肺癌的肿瘤发展机制提供了见解，并为靶向治疗策略指明了方向。在这篇综述中，我们重点介绍了在各种非小细胞肺癌亚型中常见的涉及细胞生长和增殖的基因的体细胞突变的文献发现，并讨论了这些发现如何与治疗策略相关。
{"title":"Somatic mutations of signaling genes in non-small-cell lung cancer","authors":"Heather R. Sanders,&nbsp;Maher Albitar","doi":"10.1016/j.cancergencyto.2010.07.134","DOIUrl":"10.1016/j.cancergencyto.2010.07.134","url":null,"abstract":"<div><p>Lung cancer is the leading cause of cancer-related deaths, with non-small-cell lung cancer (NSCLC) accounting for approximately 85% of cases. A significant proportion of NSCLC cases are not diagnosed until a late stage, when aggressive treatments are required but often prolong survival only modestly. Recent advances in molecular characterization of NSCLC have enabled identification of numerous cell growth and proliferation pathways that are disrupted in these tumors. This knowledge has provided insight into the mechanisms of tumor development in various histologic subtypes of NSCLC and has pointed the way toward targeted treatment strategies. In this review, we highlight literature findings of somatic mutations in genes involved in cell growth and proliferation that are commonly found in the various subtypes of NSCLC, and we discuss how these findings may relate to treatment strategies.</p></div>","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Pages 7-15"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29359255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 51
Differentially expressed micro-RNAs in clear cell renal cell carcinoma 透明细胞肾细胞癌中微rna的差异表达
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.060
Klaas Kok , Gerben Duns , Anke van den Berg , Geert Harms , Inge van Duivenbode , Robert Hofstra , Eva van den Berg-de Ruiter
{"title":"Differentially expressed micro-RNAs in clear cell renal cell carcinoma","authors":"Klaas Kok ,&nbsp;Gerben Duns ,&nbsp;Anke van den Berg ,&nbsp;Geert Harms ,&nbsp;Inge van Duivenbode ,&nbsp;Robert Hofstra ,&nbsp;Eva van den Berg-de Ruiter","doi":"10.1016/j.cancergencyto.2010.07.060","DOIUrl":"https://doi.org/10.1016/j.cancergencyto.2010.07.060","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 71"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.060","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92010831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interaction of solid malignant tumours with optical beams 实体恶性肿瘤与光束的相互作用
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.071
M.L. Pascu , R. Fumarel , M. Gherghe
{"title":"Interaction of solid malignant tumours with optical beams","authors":"M.L. Pascu ,&nbsp;R. Fumarel ,&nbsp;M. Gherghe","doi":"10.1016/j.cancergencyto.2010.07.071","DOIUrl":"https://doi.org/10.1016/j.cancergencyto.2010.07.071","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 77"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91995843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The contribution of ABC transporters to drug resistance in a realistic mouse mammary tumor model 现实小鼠乳腺肿瘤模型中ABC转运蛋白对耐药的贡献
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.044
Piet Borst , Sven Rottenberg , Jos Jonkers , Serge Zander , Marina Pajic , Janneke Jaspers
{"title":"The contribution of ABC transporters to drug resistance in a realistic mouse mammary tumor model","authors":"Piet Borst ,&nbsp;Sven Rottenberg ,&nbsp;Jos Jonkers ,&nbsp;Serge Zander ,&nbsp;Marina Pajic ,&nbsp;Janneke Jaspers","doi":"10.1016/j.cancergencyto.2010.07.044","DOIUrl":"https://doi.org/10.1016/j.cancergencyto.2010.07.044","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 64"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91995844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gobal DNA methylation in fetal human germ cells and germ cell tumors: correlation with differentiation and cisplatin resistance 胚胎人类生殖细胞和生殖细胞肿瘤的整体DNA甲基化:与分化和顺铂耐药的相关性
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.045
Leendert Looijenga , Hendrik Wermann , Hans Stoop , Ad Gillis , Friedemann Honecker , Ruud van Gurp , Ole Ammerpohl , Julia Richter , Wolter Oosterhuis , Carsten Bokemeyer
{"title":"Gobal DNA methylation in fetal human germ cells and germ cell tumors: correlation with differentiation and cisplatin resistance","authors":"Leendert Looijenga ,&nbsp;Hendrik Wermann ,&nbsp;Hans Stoop ,&nbsp;Ad Gillis ,&nbsp;Friedemann Honecker ,&nbsp;Ruud van Gurp ,&nbsp;Ole Ammerpohl ,&nbsp;Julia Richter ,&nbsp;Wolter Oosterhuis ,&nbsp;Carsten Bokemeyer","doi":"10.1016/j.cancergencyto.2010.07.045","DOIUrl":"https://doi.org/10.1016/j.cancergencyto.2010.07.045","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 64"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92114144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of oncogenes in 17p11.2-p12 implicated in osteosarcoma tumorigenesis 与骨肉瘤肿瘤发生有关的17p11.2-p12癌基因的鉴定
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.070
J. Both , J. Bras , G.R. Schaap , F. Baas , T.J.M. Hulsebos
{"title":"Identification of oncogenes in 17p11.2-p12 implicated in osteosarcoma tumorigenesis","authors":"J. Both ,&nbsp;J. Bras ,&nbsp;G.R. Schaap ,&nbsp;F. Baas ,&nbsp;T.J.M. Hulsebos","doi":"10.1016/j.cancergencyto.2010.07.070","DOIUrl":"10.1016/j.cancergencyto.2010.07.070","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 76"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.070","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"98301246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of ‘minor’ mismatch repair gene unclassified variants with hereditary non-polyposis colorectal cancer: probability of synergistic effects “轻微”错配修复基因未分类变异与遗传性非息肉病性结直肠癌的关联:协同效应的可能性
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.014
Francesca Duraturo , Raffaella Liccardo , Angela Cavallo , Marina De Rosa , Paola Izzo
{"title":"Association of ‘minor’ mismatch repair gene unclassified variants with hereditary non-polyposis colorectal cancer: probability of synergistic effects","authors":"Francesca Duraturo ,&nbsp;Raffaella Liccardo ,&nbsp;Angela Cavallo ,&nbsp;Marina De Rosa ,&nbsp;Paola Izzo","doi":"10.1016/j.cancergencyto.2010.07.014","DOIUrl":"10.1016/j.cancergencyto.2010.07.014","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 49"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"97796269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular genetic alterations in prostate cancer and its microenvironment 前列腺癌的分子遗传改变及其微环境
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.088
Tatiana Kekeeva , Larisa Zavalishina , Yulia Andreeva , Georgy Frank , Marina Nemtsova , Dmitry Zaletaev
{"title":"Molecular genetic alterations in prostate cancer and its microenvironment","authors":"Tatiana Kekeeva ,&nbsp;Larisa Zavalishina ,&nbsp;Yulia Andreeva ,&nbsp;Georgy Frank ,&nbsp;Marina Nemtsova ,&nbsp;Dmitry Zaletaev","doi":"10.1016/j.cancergencyto.2010.07.088","DOIUrl":"10.1016/j.cancergencyto.2010.07.088","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 85"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.088","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"112379900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Genome-wide profiling to decipher transformation pathways 全基因组分析破译转化途径
Cancer Genetics and Cytogenetics
Pub Date : 2010-11-01 DOI: 10.1016/j.cancergencyto.2010.07.002
Henk Stunnenberg
{"title":"Genome-wide profiling to decipher transformation pathways","authors":"Henk Stunnenberg","doi":"10.1016/j.cancergencyto.2010.07.002","DOIUrl":"https://doi.org/10.1016/j.cancergencyto.2010.07.002","url":null,"abstract":"","PeriodicalId":55596,"journal":{"name":"Cancer Genetics and Cytogenetics","volume":"203 1","pages":"Page 44"},"PeriodicalIF":0.0,"publicationDate":"2010-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cancergencyto.2010.07.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136517271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
类型
全部 化学•材料 生命科学 医学 物理 工程技术 环境•农林 材料科学 地球科学 法学 管理学 化学 环境科学与生态学 计算机科学 教育学 经济学 农林科学 人文科学 生物学 数学 物理与天体物理 心理学 综合性期刊 其他 工业工程 理学 历史学 农学 文学 信息工程
数据库
全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley
期刊
Cancer Genetics and Cytogenetics
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
﹀
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们：info@booksci.cn
Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1