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Pain and Functional Outcomes Following Vertebroplasty for Vertebral Compression Fractures: A Tertiary Center Experience 椎体压缩性骨折椎体成形术后的疼痛和功能结果:三级中心经验
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000132
S. Mukherjee, J. Yeh, H. Ellamushi
Introduction:There is a dearth of comparative outcome data on vertebroplasty for the treatment of vertebral compression fractures (VCF) according to vertebral level, number of levels, and etiology. The aim of this study was to investigate improvement of pain and function following vertebroplasty for a heterogenous cohort of patients with medically refractory VCF. Materials and Methods:A prospective observational study was conducted on a cohort of consecutive patients undergoing vertebroplasty following at least 4 weeks of failed medical management, between April 2007 and March 2012 at a single Neurosurgical center. Pain Visual Analogue Scale (VAS) scores, Oswestry Disability Index (ODI) scores, analgesic usage, and complications were recorded preoperatively and at 1 day, 1 week, 1 month, 6 months, and 1 year postoperatively. Intraoperative vertebral body biopsy was performed routinely. Results:202 levels were augmented in 147 patients. The most common levels augmented were T12 (17%), L1 (18%), and L4 (10%). Significant reductions in pain VAS and ODI scores were evident at day 1 and sustained at up to 1 year postoperatively (P<0.001). They were not dependent on the level of fracture (T3-10, T11-L2, L3-S1) (P>0.05), number of levels treated (single level, 2 levels, >2 levels) (P>0.05), or etiology of VCF (P>0.05). At 1 year postoperatively, 79% (113/142) had no or reduced analgesic usage. The complication rate was 6% (9/147). There were 5 mortalities, none of which were directly related to surgery. Conclusions:Vertebroplasty for medically refractory VCF may offer sustained improvement in pain and function. The procedure is associated with low morbidity and mortality.
根据椎体水平、水平数和病因,椎体成形术治疗椎体压缩性骨折(VCF)的比较结果数据缺乏。本研究的目的是调查一组难治性VCF患者椎体成形术后疼痛和功能的改善。材料和方法:在2007年4月至2012年3月间,在一个神经外科中心对连续接受椎体成形术的患者进行了一项前瞻性观察性研究,这些患者在至少4周的医疗管理失败后接受了椎体成形术。术前、术后1天、1周、1个月、6个月和1年分别记录疼痛视觉模拟评分(VAS)、Oswestry残疾指数(ODI)评分、镇痛药使用情况和并发症。术中常规进行椎体活检。结果:147例患者中202个水平升高。最常见的是T12(17%)、L1(18%)和L4(10%)。疼痛VAS和ODI评分在术后第1天明显降低,并持续到术后1年(P0.05),治疗水平(单水平,2水平,>水平)(P>0.05),或VCF病因(P>0.05)。术后1年,79%(113/142)患者没有或减少使用镇痛药。并发症发生率为6%(9/147)。有5例死亡,没有一例与手术直接相关。结论:椎体成形术治疗难治性VCF可持续改善疼痛和功能。该手术的发病率和死亡率较低。
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引用次数: 0
Four Cases of Unusual Complete Cervical Ribs Articulating With the Hypertrophied Scalene Tubercle With Different Clinical Presentations 不同临床表现的异常完全性颈肋关节伴斜角结节肥大4例
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000128
Vedat Uruç, R. Özden, Aydıner Kalacı, Seyit K. Başarslan, H. Bayaroğullari
Thoracic outlet syndrome (TOS) is defined as the signs and symptoms caused by compression of brachial plexus and subclavian vessels in the cervicoaxillary region. Cervical ribs are very rare causes of TOS. Most of them are asymptomatic and incidentally diagnosed during routine chest x-ray. We presented here 4 cases of unusual cervical ribs articulating with hypertrophied scalene tubercle with different clinical presentations including: TOS, palpable mass at the supraclavicular region, and asymptomatic. TOS was treated surgically with good results. In conclusion, complete cervical costa, articulating with hypertrophied scalene tubercle is a very rare cause of TOS. Scalenotomy and complete resection of the cervical rib is a good choice for treatment. In addition, the cervical ribs should be considered in the differential diagnosis of the palpable masses seen at the supraclavicular regions. Plain radiographs are enough for diagnosis; however, 3-dimensional computerized tomography provides many advantages in preoperative surgical planning and demonstrating the articulating structure of the cervical ribs in a detailed manner.
胸廓出口综合征(TOS)的定义是由于颈腋区臂丛和锁骨下血管受压而引起的体征和症状。颈肋是非常罕见的TOS病因。大多数是无症状的,在常规胸片检查时偶然发现。我们在此报告4例不寻常的颈肋关节并肥大的斜角结节,其临床表现不同,包括:TOS,锁骨上区可触及肿块,无症状。手术治疗TOS效果良好。综上所述,完全性颈突伴肥大的斜角结节是一种非常罕见的致TOS的病因。颈椎骨切除和颈椎骨全切除术是治疗颈椎病的良好选择。此外,在鉴别诊断锁骨上可见肿块时,应考虑颈肋。x线平片足以诊断;然而,三维计算机断层扫描在术前手术计划和详细显示颈肋骨的关节结构方面提供了许多优势。
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引用次数: 3
Recurrent Lumbar Disk Herniation With or Without Posterolateral Fusion 复发性腰椎间盘突出伴或不伴后外侧融合
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000126
A. Zaater, Alaa Azzazi, Sameh A. Sakr, Ahmed M. Elsayed
Study Design:A prospective study assessing the outcomes of repeat surgery for recurrent lumbar disc herniation. Objectives:To evaluate the results of repeat surgery for recurrent disc herniation, and compare the results of disc excision with and without posterolateral fusion. Methods:The study included 39 patients who underwent disc excision with or without posterolateral fusion, with an average follow-up of 66.7 months (range, 24-116 months). Clinical symptoms were assessed based on the Japanese Orthopedic Association Back Scores. Medical and surgical data were examined and analyzed, including pain-free interval, intraoperative blood loss, length of surgery, and postoperative hospital stay. Results:Clinical outcome was excellent or good in 84.6% of patients, including 83.3% of patients undergoing a discectomy alone, and 84.6% of patients with posterolateral fusion. The recovery rate was 84.4%, and the difference between the fusion and nonfusion groups was insignificant (P=0.725). The difference in the postoperative back pain score was also insignificant (P=0.821). These two groups were not different in terms of age, pain-free interval, and follow-up duration. Intraoperative blood loss, length of surgery, and length of hospitalization were significantly less in patients undergoing discectomy alone than in patients with fusion. Conclusions:Repeat surgery for recurrent sciatica is effective in cases of true recurrent disc herniation. Disc excision alone is recommended for managing recurrent disc herniation.
研究设计:一项评估反复手术治疗复发性腰椎间盘突出症疗效的前瞻性研究。目的:评价反复手术治疗复发性椎间盘突出症的效果,并比较后外侧融合术和非后外侧融合术椎间盘切除的效果。方法:该研究包括39例椎间盘切除合并或不合并后外侧融合的患者,平均随访66.7个月(范围24-116个月)。临床症状根据日本骨科协会背部评分进行评估。检查和分析医疗和手术数据,包括无痛间隔时间、术中出血量、手术时间和术后住院时间。结果:84.6%的患者临床结果为优或良,其中83.3%的患者单独行椎间盘切除术,84.6%的患者行后外侧融合。术后恢复率为84.4%,融合组与未融合组差异无统计学意义(P=0.725)。术后腰痛评分差异无统计学意义(P=0.821)。两组在年龄、无痛间隔、随访时间等方面无差异。单独行椎间盘切除术的患者术中出血量、手术时间和住院时间明显少于行融合术的患者。结论:反复手术治疗复发性坐骨神经痛是治疗复发性椎间盘突出的有效方法。单纯椎间盘切除是治疗复发性椎间盘突出的推荐方法。
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引用次数: 1
An Investigation of Weather Factors Effect on Bell’s Palsy by Comparison With 2 Capital Cities in China 气象因素对贝尔氏麻痹的影响——以中国两个首都城市为例
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000196
Tao Yang, Li Zhang, Ying Zhang, Wenyuan Liu, Xuezhong Wei, Zequan Hua
Aim:To evaluate the temperature change (one of the key weather factors) is relevant to Bell’s palsy (BP) occurrence and what kind of role does temperature change play in causing BP, via BP occurrence comparison of 2 capital cities. Materials and Methods:The epidemiological study of BP was conducted between the capital city of Liaoning Province, Shenyang (population: about 7.5 million in 2007 and 2008, climate type: temperate continental monsoon climate) and the capital city of Shanxi Province, Xi’an (population: about 6.5million in 2007 and 2008, climate type: warm sub-humid continental monsoon climate) in Table 1. Result:There were statistically significantly different in BP’s incidence rate between 2 kinds of jobs in 2 different capital cities (P<0.05), in BP’s incidence rate among 4 different seasons even in 2 different capital cities (P<0.05), in BP’s disease extent in 2different capital cities (P<0.05), in disease inducement between 2 different capital cities (P<0.05), and between 4 kinds of BP’s prognosis in 2 different capital cities (P<0.05). Conclusions:There was statistically significant correlation between weather change/character and the actual incidence of BP. The real factors that triggered the incidence of BP should be invested in further study.
目的:通过对2个省会城市贝尔氏麻痹(BP)发生情况的比较,评价气温变化(关键天气因素之一)与贝尔氏麻痹(BP)发生的关系以及气温变化在引起贝尔氏麻痹中起何种作用。材料与方法:在表1中,对辽宁省会城市沈阳(2007年和2008年人口约750万,气候类型为温带大陆性季风气候)和山西省会城市西安(2007年和2008年人口约650万,气候类型为温暖亚湿润大陆性季风气候)进行了BP流行病学研究。结果:2个省会城市2种工种BP发病率差异有统计学意义(P<0.05), 2个省会城市4个季节BP发病率差异有统计学意义(P<0.05), 2个省会城市BP发病程度差异有统计学意义(P<0.05), 2个省会城市BP发病诱因差异有统计学意义(P<0.05), 2个省会城市4种BP预后差异有统计学意义(P<0.05)。结论:天气变化/特征与BP实际发病率有统计学意义。引发BP发病的真正因素有待进一步研究。
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引用次数: 1
A Germinoma Involving Basal Ganglia: Case Report 累及基底神经节的生殖细胞瘤1例
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000049
Xie Yuebing, X. Anqi, Wang Xiang, Y. Chao, C. Jing
The central nervous system germinoma, as a malignant tumor, mainly occurs in the pineal gland region or hypothalamic area, and tends to involve adolescents. Germinoma occurring in the basal ganglia is very easy to be mistaken as other pathologic tumors because of its relative occurrence and atypical imaging performance. Here we report the case of a young man suffering from an atypical germinoma and discuss its differential diagnosis in imaging.
中枢神经系统生殖细胞瘤是一种恶性肿瘤,主要发生在松果体区或下丘脑区,易累及青少年。发生于基底节区的生殖细胞瘤因其相对多发且影像学表现不典型,极易与其他病理性肿瘤混淆。在这里,我们报告一个年轻人患有非典型生殖细胞瘤,并讨论其影像学鉴别诊断。
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引用次数: 0
Chiari 0 Malformation With Multiple Café Au Lait Spots: A Case Report Chiari 0畸形伴多咖啡渍斑点1例报告
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000119
A. Kamgarpour, E. Moradi, Alireza Showraki, N. Derakhshan, M. Jamali
Chiari type 0 malformation (CM-0), first introduced in 1998, is a new subtype of Chiari malformation with no signs of tonsillar ectopia. We present a case of CM-0 with multiple cafe au lait spots. This case presentation could indicate the possibility of an unrecognized correlation in the pathogenesis of CM-0 and formation of cafe au lait spots (isolated or as features of Legius syndrome/neurofibromatosis type 1).
Chiari 0型畸形(CM-0)于1998年首次被介绍,是一种新的Chiari畸形亚型,没有扁桃体异位的迹象。我们提出了一个CM-0与多个奶泡点的病例。本病例的表现可能提示CM-0的发病机制与咖啡色斑的形成(孤立的或作为Legius综合征/ 1型神经纤维瘤病的特征)之间存在未被认识的相关性。
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引用次数: 1
Supracerebellar Subarachnoid Hemorrhage After Evacuation of Supratentorial Chronic Subdural Hematoma 小脑上幕上慢性硬膜下血肿术后蛛网膜下腔出血
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000127
H. Yamakawa, N. Tamakawa, H. Watarai, T. Tanigawara
Subarachnoid hemorrhage located in the supracerebellar cistern is an unusual complication of supratentorial neurosurgery. To the best of our knowledge, only 5 case reports have described the occurrence of this rare hemorrhage after burr hole surgery/drainage for the treatment of chronic subdural hematoma. We present the case of a patient with this rare postoperative complication of subarachnoid hemorrhage located in the supracerebellar cistern immediately after the burr hole evacuation of chronic subdural hematoma without continuous subdural drainage. A possible underlying mechanism is also discussed. Although the complication may be associated with significant morbidity and mortality, most cases follow a benign clinical course as observed in our case.
摘要位于小脑上池的蛛网膜下腔出血是幕上神经外科的罕见并发症。据我们所知,只有5例报告描述了慢性硬膜下血肿的钻孔手术/引流后发生这种罕见的出血。我们报告一例罕见的术后并发症,即慢性硬脑膜下血肿钻孔引流后立即出现位于小脑上池的蛛网膜下腔出血,而没有持续的硬脑膜下引流。本文还讨论了一种可能的潜在机制。虽然并发症可能与显著的发病率和死亡率相关,但正如本病例所观察到的,大多数病例遵循良性临床过程。
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引用次数: 0
A Familial Case of Saethre-Chotzen Syndrome in Japan 日本家族性三甲综合征1例
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000131
N. Mitsukawa, Takashi Hayashi, K. Satoh
Saethre-Chotzen syndrome is extremely rare in Japan. We experienced a familial case of Saethre-Chotzen syndrome in 4 individuals of 3 generations. In all 4 individuals, a mutation in the TWIST gene was observed by a gene test. Some of these patients underwent surgical correction of brachycephaly and blepharoptosis with good results.
saethree - chotzen综合征在日本极为罕见。我们经历了一个家族病例saethree - chotzen综合征在4个人3代。在所有4个个体中,通过基因检测观察到TWIST基因突变。其中一些患者接受了短头畸形和上睑下垂的手术矫正,效果良好。
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引用次数: 0
Rapidly Neurological Deficit Preoperative and Surgery-related Complications Occurred Postoperatively Caused by an Epidural Mass of B-Cell Lymphoblastic Lymphoma (Case Report) b细胞淋巴母细胞淋巴瘤硬膜外肿块引起的术前及术后并发症(附1例报告)
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000144
Si-qing Huang, Shuhui Gong, Jia-gang Liu
The aim of this paper is to present a 13-year-old patient with bilateral lower limb paralysis and bladder incontinence rapidly progressive within a week. Spine magnetic resonance imaging (MRI) showed a giant epidural mass extending from C6 to T6 and involving soft tissue paraspinally. A surgical procedure was performed, and postoperative histopathologic examinations proved that the mass was B-cell lymphoblastic lymphoma. Preoperative symptoms were not relieved because of some complications, which occurred postoperative. Decreased blood platelets caused a serious coagulation function disorder and discontinuity hyperpyrexia postoperatively. The patient had a poor prognosis and died 1 month postoperatively. When B-cell lymphoma has a serious neurological deficit with bone morrow involvement, surgical treatment should be considered cautiously.
本文的目的是提出一个13岁的病人,双侧下肢瘫痪和膀胱失禁在一周内迅速进展。脊柱磁共振成像(MRI)显示一个巨大的硬膜外肿块,从C6延伸到T6,并累及棘旁软组织。术后组织病理学检查证实肿块为b细胞淋巴母细胞淋巴瘤。由于术后出现了一些并发症,术前症状未得到缓解。术后血小板减少导致严重凝血功能障碍和间断高热。患者预后不佳,术后1个月死亡。当b细胞淋巴瘤有严重的神经功能缺损并累及骨骼时,应谨慎考虑手术治疗。
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引用次数: 0
Comparison of Results of 4 Methods of Surgery in Grade 1 Lumbosacral Spondylolisthesis 4种手术方法治疗1级腰椎滑脱的效果比较
Q Medicine Pub Date : 2016-02-01 DOI: 10.1097/WNQ.0000000000000197
S. Fariborz, Mohammad Gharedaghi, A. Khosravi, M. Samini
Introduction:There are 3 ways for the treatment of patients for spondylolisthesis grade 1 in lumbosacral region associating with lumbar disk herniation or lumbar stenosis: pedicular screw fixation method alone; pedicular screw with insertion of trans lumbar interbody fusion (TLIF), or with posterior lumbar interbody fusion (PLIF). Interestingly, all methods have associated with satisfactory results. However, which method is superior for the treatment of such patients still has remained controversial. Materials and Methods:Patients with clinical signs and symptoms of disk herniation or lumbar canal stenosis and also spondylolysthesis grade 1 were selected, who had randomly undergone pedicle screw and posterior fusion surgery, pedicle screw and TLIF surgery, pedicle screw and PLIF surgery, or without instrumentation and fusion, in neurosurgery section in Mashhad, from 2009 to 2011. Afterwards, clinical symptoms, radiologic study results, amount of fusion in terms of Brantigan and Stefee indices, and functional improvement by Oswestry Disability Index were recorded after 6 and 12 months from surgery, respectively. Results:Of 120 patients who were analyzed in 4 treatment groups, age and sex distribution was matched. Also, L4-L5 involvement was more common in 3 groups with a normal distribution. Statistically, Oswestry Disability Index had a significant reduction after operation, and no significant differences were observed among the 3 study groups. These groups showed no significant variation in degree of fusion and Brantigan and Stefee index, but in the group which had been undergone surgery without instrumentation and fusion, the difference was significant. Conclusions:After a 12-month follow-up, the 3 procedures of TLIF, PLIF, and posterior fusion pedicle screw did not show any difference in functional improvement of the patients, degree of fusion, and complications significantly, whereas all of them had a significant preference rather than the fourth group, in which no instrumentation and fusion was applied.
导语:腰骶区1级滑脱伴腰椎间盘突出或腰椎管狭窄患者的治疗方法有3种:单纯椎弓根螺钉固定术;椎弓根螺钉置入经腰椎椎间融合术(tliff)或后路腰椎椎间融合术(PLIF)。有趣的是,所有的方法都有令人满意的结果。然而,哪种方法更适合治疗此类患者仍存在争议。材料与方法:选取2009 - 2011年马什哈德神经外科随机行椎弓根螺钉与后路融合术、椎弓根螺钉与TLIF术、椎弓根螺钉与PLIF术或未行内固定融合术的临床症状和体征为椎间盘突出或腰椎管狭窄且伴有1级腰椎滑脱的患者。术后6个月和12个月分别记录临床症状、影像学检查结果、Brantigan和Stefee指数融合量和Oswestry功能改善情况。结果:120例患者分为4个治疗组,年龄、性别分布基本吻合。L4-L5受累在呈正态分布的3组中更为常见。统计学上,术后Oswestry残疾指数明显降低,3个研究组间差异无统计学意义。这些组在融合程度和Brantigan和Stefee指数上没有明显的变化,但在没有内固定和融合的手术组中,差异有显著性。结论:经过12个月的随访,TLIF、PLIF和后路融合椎弓根螺钉3种术式在患者功能改善、融合程度和并发症方面无明显差异,但均较不行内固定融合的第四组有明显的优先性。
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引用次数: 12
期刊
Neurosurgery Quarterly
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