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Use of Suzetrigine, a Selective Sodium Channel Blocker, in Postoperative Pain Management for an Adolescent Patient With Hereditary Neuropathy: A Case Report. 选择性钠通道阻滞剂suzetriine在青少年遗传性神经病变患者术后疼痛管理中的应用:1例报告。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-03 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002114
Sindhuja Reddy Nimma, Tugba Yavuz Kivanc, Matthew M Colontonio

Suzetrigine is a unique, nonopioid oral analgesic that selectively inhibits voltage-gated sodium channels in peripheral nerves. The Food and Drug Administration (FDA) recently approved it, and we present the first successful use of suzetrigine in a 16-year-old boy with hereditary neuropathy who underwent foot reconstruction surgery. His postoperative pain management plan included a sciatic nerve catheter, a 14-day course of suzetrigine, opioids, and home medications. His pain was well controlled with no side effects. Within 24 hours of stopping suzetrigine, the patient's pain rapidly intensified, suggesting suzetrigine's effectiveness in postoperative pain management in an adolescent patient with neuropathy.

舒三嗪是一种独特的非阿片类口服镇痛药,可选择性抑制周围神经中的电压门控钠通道。美国食品和药物管理局(FDA)最近批准了suzetrigine,我们介绍了首例成功使用suzetrigine治疗一名16岁的遗传性神经病男孩,他接受了足部重建手术。术后疼痛管理计划包括坐骨神经导管、14天疗程的舒三嗪、阿片类药物和家庭用药。他的疼痛控制得很好,没有副作用。停用suzetriine后24小时内,患者疼痛迅速加剧,提示suzetriine在青少年神经病变患者术后疼痛管理中的有效性。
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引用次数: 0
Comparison of Endotracheal Intubation Performance Using Video Laryngoscopy With and Without AI-Based Visual Assistance: A Manikin Pilot Study. 有和没有人工智能视觉辅助的视频喉镜下气管插管性能的比较:一项人体试验研究。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-03 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002110
Georgiy Danylenko, Sean D Jeffries, Eric D Pelletier, Oliver Cafferty, Emma Rispler, Pascal Laferriere-Langlois, Thomas M Hemmerling

This study investigated whether artificial intelligence (AI)-based visual assistance in video laryngoscopy (VL) could be a solution to reduce the technique's learning curve. Twenty volunteers with no prior intubation experience were randomly assigned to 2 equal groups: standard VL or AI-enhanced VL (AI-VL). Participants performed 10 consecutive intubations. The AI-VL group showed a trend toward steeper learning curves for intubation time (P > .05). The AI system functioned as a real-time virtual instructor, which provided visual feedback that helped maintain Cormack-Lehane (C-L) views.

本研究调查了视频喉镜(VL)中基于人工智能(AI)的视觉辅助是否可以成为减少技术学习曲线的解决方案。20名无插管经验的志愿者随机分为标准VL组和人工智能增强VL组(AI-VL)。参与者进行了10次连续插管。AI-VL组插管时间学习曲线呈陡峭趋势(P < 0.05)。该人工智能系统充当实时虚拟讲师,提供视觉反馈,帮助维持科马克-勒汉(C-L)观点。
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引用次数: 0
Respiratory Recovery in a Critically Ill Patient With Rib Fractures Using the Serratus Posterior Superior Intercostal Plane Block: A Case Report. 应用后上锯肌肋间平面阻滞治疗肋骨骨折危重患者呼吸恢复1例。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-03 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002089
Ilke Tamdogan, Tamer Tamdogan

We present a case of a patient with multiple rib fractures who was managed in the intensive care unit using a serratus posterior superior intercostal plane (SPSIP) block. The SPSIP block is a relatively new interfascial plane block technique that provides broad thoracic dermatomal coverage for analgesia. In trauma patients with multiple rib fractures, pain control, preservation of respiratory function, prevention of pulmonary complications, and facilitation of early mobilization are important. This case suggests that the SPSIP block may represent a safe, effective, and opioid-sparing analgesic option in critically ill patients with thoracic trauma-related respiratory compromise and warrants further investigation.

我们提出了一例患者多肋骨骨折谁是管理在重症监护病房使用锯肌后上肋间平面(SPSIP)块。SPSIP阻滞是一种相对较新的筋膜间面阻滞技术,可提供广泛的胸廓皮层覆盖止痛。对于多发肋骨骨折的创伤患者,控制疼痛、保持呼吸功能、预防肺部并发症和促进早期活动是重要的。该病例表明,SPSIP阻滞可能是一种安全、有效和节省阿片类药物的镇痛选择,适用于胸椎创伤相关呼吸损害的危重患者,值得进一步研究。
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引用次数: 0
Enhanced Ventilation Strategies in Bariatric Surgery: A Case Report of Flow-Controlled Ventilation in an Extremely Obese Patient Undergoing Robot-Assisted Bariatric Surgery. 在减肥手术中增强通气策略:一个在机器人辅助减肥手术中进行流量控制通气的极度肥胖患者的病例报告。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-02 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002111
David Sohm, Marcus J Schultz, Timur Yurttas

Intraoperative ventilation in obese patients is challenging, eg, during robot-assisted surgery, where altered respiratory mechanics often require high levels of positive end-expiratory pressure (PEEP) and oxygen. With high intrathoracic pressures, hemodynamic instability may occur, while oxygenation can remain impaired. However, a gap of knowledge exists regarding the efficacy of flow-controlled ventilation (FCV) in patients with extreme obesity undergoing bariatric surgery. We describe an obese patient (body mass index [BMI] 68.6kg/m²) in whom conventional ventilation resulted in impaired oxygenation and respiratory compliance. FCV markedly improved gas exchange. Implementing FCV in high-risk obese patients may enhance gas exchange, limit ventilator-induced lung injury, and minimize hemodynamic compromise.

肥胖患者的术中通气具有挑战性,例如,在机器人辅助手术中,改变的呼吸力学通常需要高水平的呼气末正压(PEEP)和氧气。当胸内高压时,可能会发生血流动力学不稳定,同时氧合仍会受损。然而,关于在接受减肥手术的极度肥胖患者中使用流量控制通气(FCV)的有效性,存在知识空白。我们描述了一位肥胖患者(体重指数[BMI] 68.6kg/m²),常规通气导致氧合和呼吸顺应性受损。FCV显著改善了气体交换。在高危肥胖患者中实施FCV可以增强气体交换,限制呼吸机引起的肺损伤,并最大限度地减少血流动力学损害。
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引用次数: 0
Combined Regional Anesthesia with Supplemental Sedation for Scapula Fracture Surgery in a High-Risk Patient: Anesthetic Management with Erector Spinae Plane and Serratus Posterior Superior Intercostal Plane Blocks. 联合区域麻醉加镇静用于高危患者肩胛骨骨折手术:竖脊肌平面和锯肌后上肋间平面阻滞的麻醉管理。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-02 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002108
Ali Nasir Günsaldi, İhsan Yüksel, Cemre Var, Bahadir Ciftci

This case report highlights a novel and effective use of a combined erector spinae plane block (ESPB) and serratus posterior superior intercostal plane block (SPSIPB) as the primary anesthetic method for a patient undergoing scapula surgery who was at high risk for general anesthesia. The combination of these 2 fascial plane blocks successfully provided surgical anesthesia and postoperative analgesia while allowing the patient to remain awake and avoid the risks associated with mechanical ventilation. This technique represents a promising opioid-sparing strategy for the management of high-risk trauma patients.

本病例报告强调了一种新颖而有效的联合竖脊肌平面阻滞(ESPB)和后上锯肌肋间平面阻滞(SPSIPB)作为接受肩胛骨手术的高危全身麻醉患者的主要麻醉方法。这两种筋膜平面阻滞的联合成功地提供了手术麻醉和术后镇痛,同时使患者保持清醒,避免了机械通气相关的风险。这项技术代表了一种有前途的阿片类药物节约策略,用于管理高危创伤患者。
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引用次数: 0
Avoiding the Vicious Cycle: Successful Extracorporeal Membrane Oxygenation Weaning via Serratus Anterior Plane Block for Postthoracotomy Pain: A Case Report. 避免恶性循环:经锯肌前平面阻滞成功体外膜氧合脱机治疗开胸术后疼痛1例报告。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-02 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002086
Annika A Brijlal, Matthew M Colontonio, Sindhuja R Nimma

Pain management after thoracotomy is particularly complex in lung transplant recipients on extracorporeal membrane oxygenation (ECMO), where anticoagulation significantly limits available treatment options. Coagulopathy constitutes a contraindication to neuraxial and deep peripheral nerve blocks due to hemorrhagic complications. Uncontrolled thoracotomy pain, hypoxia due to increasing opioid use, and hemodynamic instability can delay successful weaning from ECMO. We present the case of a patient on bivalirudin after undergoing a thoracotomy for a right lung transplantation. This case highlights the successful use of a serratus anterior plane block (SAPB) as an alternative approach to neuraxial anesthesia in an anticoagulated patient, optimizing analgesia and facilitating recovery postthoracotomy.

对于接受体外膜氧合(ECMO)治疗的肺移植患者,开胸术后的疼痛管理尤其复杂,抗凝治疗明显限制了可用的治疗选择。凝血功能障碍是由于出血性并发症导致的轴神经和深周围神经阻滞的禁忌症。不受控制的开胸疼痛、阿片类药物使用增加引起的缺氧和血流动力学不稳定可延迟ECMO的成功脱机。我们提出的情况下,病人比伐鲁定后,接受开胸手术右肺移植。本病例强调了在抗凝患者中成功使用前锯肌阻滞(SAPB)作为神经轴麻醉的替代方法,优化了镇痛并促进了开胸术后的恢复。
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引用次数: 0
A Novel Nebulization-Assisted Topicalization Device for Flexible Bronchoscopic-Guided Awake Nasotracheal Intubation: A Case Report. 一种用于柔性支气管镜引导清醒鼻气管插管的新型雾化辅助局部化装置:1例报告。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-02 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002094
Devalina Goswami, Sushmita Bairagi

Awake flexible bronchoscopic (FB)-guided nasotracheal intubation is often necessary for managing difficult airways, especially in maxillofacial surgeries. We present 2 cases used a novel device for airway topicalization with a local anesthetic (LA) solution. This device integrates a nasal trumpet with a nebulization chamber to deliver 4% lidocaine, effectively anesthetizing the nasal cavity, nasopharynx, and the vocal cords. This technique was successfully used in 2 patients, ensuring smooth and efficient awake FB-guided nasotracheal intubation while minimizing adverse effects such as epistaxis, coughing, or discomfort.

清醒柔性支气管镜(FB)引导下的鼻气管插管通常是处理困难气道的必要手段,特别是在颌面外科手术中。我们报告了2例使用局部麻醉(LA)溶液的新型气道局部化装置的病例。该装置集成了一个鼻喇叭和一个雾化室,可以输送4%的利多卡因,有效地麻醉鼻腔、鼻咽和声带。该技术成功应用于2例患者,确保了清醒fb引导的鼻气管插管顺利有效,同时最大限度地减少了鼻出血、咳嗽或不适等不良反应。
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引用次数: 0
A Case Report of Timely Interventions in Postpartum Hemorrhage: The Role of Real-Time Surveillance, Uncrossmatched Blood Products, and Aortic Compression. 及时干预产后出血1例报告:实时监测、非交叉匹配血液制品和主动脉压迫的作用。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-12-02 eCollection Date: 2025-12-01 DOI: 10.1213/XAA.0000000000002103
Manal Saad, Shubhangi Singh, Kyle Latack, Tom T Klumpner, Carlo Pancaro

A 41-year-old G2P1 underwent a vaginal delivery complicated by a retained placenta, uterine atony, and a massive postpartum hemorrhage of 4000 mL. Despite hypotension, care was not escalated, possibly due to the absence of tachycardia, pallor, or mental status changes. While maternal early warning criteria failed to trigger an alert, an electronic real-time surveillance platform activated a team response. The patient became unresponsive with a systolic blood pressure of 47 mm Hg and severe hypoxemia. Aortic compression restored consciousness. She was resuscitated with uncrossmatched blood and never-frozen plasma. Rotational thromboelastometry showed preserved coagulation. Automated alerts and rapid intervention were lifesaving.

一位41岁的G2P1接受了阴道分娩,并发胎盘残留,子宫张力,产后大出血4000 mL。尽管有低血压,但护理没有升级,可能是由于没有心动过速,苍白或精神状态改变。虽然产妇早期预警标准未能触发警报,但电子实时监测平台启动了团队响应。患者无反应,收缩压47毫米汞柱,严重低氧血症。主动脉压迫恢复意识。她是用不匹配的血液和未冷冻的血浆复苏的。旋转血栓弹性测量显示凝血保存完好。自动警报和快速干预挽救了生命。
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引用次数: 0
One-Lung Jet Ventilation for Robotic-Assisted Tracheal Resection in Close Proximity to the Carina: A Case Report. 近隆突机器人辅助气管切除的单肺喷射通气一例报告。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-11-10 eCollection Date: 2025-11-01 DOI: 10.1213/XAA.0000000000002102
Dhilan A R Thuraisingham, Wael N Yacoub, Michael Y Chang, Charles Lee, Antonio Hernandez Conte

This case report describes a novel ventilation method to safely accommodate robotic-assisted tracheobronchial surgery. The patient with a tracheal tumor 2.5 cm above the carina underwent a robotic-assisted tracheal resection. Single-lung jet ventilation was performed using the Monsoon Jet Ventilator during the tracheal resection and anastomosis. This allowed the surgeon to operate without interruption by eliminating an intermittent apneic technique. Through a small chest incision, the surgeon robotically advanced a Laserjet 40 tube into the transected end of the distal trachea. The endotracheal tube was directed into the left main bronchus and the patient was successfully managed with single-lung jet ventilation.

本病例报告描述了一种新的通气方法,以安全适应机器人辅助气管支气管手术。患有隆突上方2.5 cm气管肿瘤的患者接受了机器人辅助的气管切除术。气管切除吻合术中采用季风喷气呼吸机进行单肺喷射通气。这使得外科医生可以通过消除间歇性呼吸暂停技术而不间断地进行手术。通过一个小的胸部切口,外科医生机器人地将激光喷射40管插入气管远端横切的末端。气管插管进入左主支气管,患者成功地接受了单肺喷射通气。
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引用次数: 0
Rectointercostal Fascial Plane Block as a Practical Option for Somatic Analgesia in Gastric Bypass Surgery: A Case Report. 直肠肋间筋膜平面阻滞作为胃分流术中躯体镇痛的实用选择:1例报告。
IF 0.6 Q4 ANESTHESIOLOGY Pub Date : 2025-11-10 eCollection Date: 2025-11-01 DOI: 10.1213/XAA.0000000000002100
Ergun Mendes, Doruk Yaylak, Yasemin Sincer, Derya Salim Uymaz, Yavuz Gurkan

We present a case demonstrating the use of the rectointercostal fascial plane block (RICPB) for postoperative analgesia in a morbidly obese patient undergoing laparoscopic gastric bypass. RICPB was easily applied under ultrasound guidance and provided effective pain control with minimal opioid use. Its anterior approach offers technical advantages in obese patients where traditional blocks are challenging. Given its simplicity, dermatomal coverage, and favorable outcomes in our case, RICPB appears to be a promising in bariatric surgery and merits further investigation.

我们提出了一个病例证明使用直肠肋间筋膜平面阻滞(RICPB)的术后镇痛在一个病态肥胖的病人接受腹腔镜胃旁路手术。超声引导下易于应用RICPB,在阿片类药物使用较少的情况下有效控制疼痛。它的前路入路为肥胖患者提供了技术优势,而传统的阻滞是具有挑战性的。考虑到它的简单性、皮肤覆盖范围和在本病例中良好的结果,RICPB在减肥手术中似乎是一种很有前途的方法,值得进一步研究。
{"title":"Rectointercostal Fascial Plane Block as a Practical Option for Somatic Analgesia in Gastric Bypass Surgery: A Case Report.","authors":"Ergun Mendes, Doruk Yaylak, Yasemin Sincer, Derya Salim Uymaz, Yavuz Gurkan","doi":"10.1213/XAA.0000000000002100","DOIUrl":"10.1213/XAA.0000000000002100","url":null,"abstract":"<p><p>We present a case demonstrating the use of the rectointercostal fascial plane block (RICPB) for postoperative analgesia in a morbidly obese patient undergoing laparoscopic gastric bypass. RICPB was easily applied under ultrasound guidance and provided effective pain control with minimal opioid use. Its anterior approach offers technical advantages in obese patients where traditional blocks are challenging. Given its simplicity, dermatomal coverage, and favorable outcomes in our case, RICPB appears to be a promising in bariatric surgery and merits further investigation.</p>","PeriodicalId":56372,"journal":{"name":"A&A practice","volume":"19 11","pages":"e02100"},"PeriodicalIF":0.6,"publicationDate":"2025-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145491112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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A&A practice
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