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Functional & Integrative Genomics最新文献

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Circular RNAs: a small piece in the heart failure puzzle 环状 RNA：心力衰竭拼图中的一小块。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-17 DOI: 10.1007/s10142-024-01386-z
Reza Eshraghi, Davood Shafie, Arash Raisi, Pouya Goleij, Hamed Mirzaei

Cardiovascular disease, specifically heart failure (HF), remains a significant concern in the realm of healthcare, necessitating the development of new treatments and biomarkers. The RNA family consists of various subgroups, including microRNAs, PIWI-interacting RNAs (piRAN) and long non-coding RNAs, which have shown potential in advancing personalized healthcare for HF patients. Recent research suggests that circular RNAs, a lesser-known subgroup of RNAs, may offer a novel set of targets and biomarkers for HF. This review will discuss the biogenesis of circular RNAs, their unique characteristics relevant to HF, their role in heart function, and their potential use as biomarkers in the bloodstream. Furthermore, future research directions in this field will be outlined. The stability of exosomal circRNAs makes them suitable as biomarkers, pathogenic regulators, and potential treatments for cardiovascular diseases such as atherosclerosis, acute coronary syndrome, ischemia/reperfusion injury, HF, and peripheral artery disease. Herein, we summarized the role of circular RNAs and their exosomal forms in HF diseases.

心血管疾病，特别是心力衰竭（HF），仍然是医疗保健领域的一个重大问题，需要开发新的治疗方法和生物标志物。RNA家族由不同的亚群组成，包括microRNA、PIWI-interacting RNA（piRAN）和长非编码RNA，这些亚群已显示出推进心衰患者个性化医疗的潜力。最近的研究表明，环状 RNA 这一鲜为人知的 RNA 亚群可能会为高血脂提供一系列新的靶点和生物标志物。本综述将讨论环状 RNA 的生物生成、其与高血脂相关的独特特征、在心脏功能中的作用以及在血液中作为生物标记物的潜在用途。此外，还将概述该领域未来的研究方向。外泌体循环RNA的稳定性使其适合作为动脉粥样硬化、急性冠状动脉综合征、缺血/再灌注损伤、高频和外周动脉疾病等心血管疾病的生物标记物、致病调节因子和潜在治疗方法。在此，我们总结了环状 RNA 及其外泌体形式在高频疾病中的作用。
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引用次数: 0
Retraction Note: Vacuolar protein sorting 35 (VPS35) acts as a tumor promoter via facilitating cell cycle progression in pancreatic ductal adenocarcinoma 撤稿说明：空泡蛋白分选 35（VPS35）通过促进胰腺导管腺癌的细胞周期进展，起到肿瘤促进剂的作用。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-16 DOI: 10.1007/s10142-024-01383-2
Yanzhi Gai, Liheng Qian, Shuheng Jiang, Jun Li, Xueli Zhang, Xiaomei Yang, Hong Pan, Yingna Liao, Huiling Wang, Shan Huang, Shan Zhang, Huizhen Nie, Mingze Ma, Hui Li
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引用次数: 0
Retraction Note: Renal enhanced CT images reveal the tandem mechanism between tumor cells and immunocytes based on bulk/single-cell RNA sequencing 撤稿说明：肾脏增强 CT 图像根据大量/单细胞 RNA 测序揭示了肿瘤细胞与免疫细胞之间的串联机制。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-15 DOI: 10.1007/s10142-024-01385-0
Haote Liang, Keming Wu, Rongrong Wu, KaTe Huang, Zhexian Deng, Hongde Chen
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引用次数: 0
Retraction Note: Ferroptosis patterns modulate immunocyte communication in tumor microenvironments: clinical value and therapeutic guidance of lung adenocarcinoma 撤稿说明：铁凋亡模式调节肿瘤微环境中的免疫细胞通讯：肺腺癌的临床价值和治疗指导。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-15 DOI: 10.1007/s10142-024-01384-1
Peng Wang, Ye Wang, Yu Wang
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引用次数: 0
Retraction Note: Denosumab treatment for progressive Enneking stage II cervical giant-cell tumor conservatively 撤稿说明：地诺单抗保守治疗进展期恩内金II期宫颈巨细胞瘤。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-14 DOI: 10.1007/s10142-024-01371-6
YiXuan Tan, Shuhan Zhang, Jinling Zhang, Tao Huang, Xiaoming Li, Xuhui Zhou, Jiefeng Zhang
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引用次数: 0
Retraction Note: BCLncRDB: a comprehensive database of LncRNAs associated with breast cancer 撤稿说明：BCLncRDB：与乳腺癌相关的 LncRNAs 综合数据库。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-14 DOI: 10.1007/s10142-024-01372-5
Swapnil Kumar, Avantika Agrawal, Vaibhav Vindal
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引用次数: 0
Correction to: Low FHL1 expression indicates a good prognosis and drug sensitivity in ovarian cancer 更正为FHL1 低表达预示着卵巢癌的良好预后和药物敏感性。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-14 DOI: 10.1007/s10142-024-01361-8
Xiaoying Chen, Yue Yu, Yuting Su, Lizhou Shi, Shanzhou Xie, Yi Hong, Xia Liu, Fuqiang Yin
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引用次数: 0
Retraction Note: Special transcriptome landscape and molecular prognostic signature of non-smoking head and neck cancer patients 撤稿说明：非吸烟头颈癌患者的特殊转录组图谱和分子预后特征。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-13 DOI: 10.1007/s10142-024-01367-2
Yaya Ji, Zixuan Zhao, Yulan Cheng, Wenxia Bu, Xinyuan Zhao, Yonghua Luo, Juan Tang
{"title":"Retraction Note: Special transcriptome landscape and molecular prognostic signature of non-smoking head and neck cancer patients","authors":"Yaya Ji,&nbsp;Zixuan Zhao,&nbsp;Yulan Cheng,&nbsp;Wenxia Bu,&nbsp;Xinyuan Zhao,&nbsp;Yonghua Luo,&nbsp;Juan Tang","doi":"10.1007/s10142-024-01367-2","DOIUrl":"10.1007/s10142-024-01367-2","url":null,"abstract":"","PeriodicalId":574,"journal":{"name":"Functional & Integrative Genomics","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction Note: RAD54L promotes progression of hepatocellular carcinoma via the homologous recombination repair pathway 撤回声明：RAD54L 通过同源重组修复途径促进肝细胞癌的进展。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-13 DOI: 10.1007/s10142-024-01365-4
Hongda Li, Haiwen Zhuang, Tengfei Gu, Guangyu Li, Yuhang Jiang, Sanrong Xu, Qing Zhou
{"title":"Retraction Note: RAD54L promotes progression of hepatocellular carcinoma via the homologous recombination repair pathway","authors":"Hongda Li,&nbsp;Haiwen Zhuang,&nbsp;Tengfei Gu,&nbsp;Guangyu Li,&nbsp;Yuhang Jiang,&nbsp;Sanrong Xu,&nbsp;Qing Zhou","doi":"10.1007/s10142-024-01365-4","DOIUrl":"10.1007/s10142-024-01365-4","url":null,"abstract":"","PeriodicalId":574,"journal":{"name":"Functional & Integrative Genomics","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction Note: Ensemble learning-based gene signature and risk model for predicting prognosis of triple-negative breast cancer 撤稿说明：基于集合学习的基因特征和风险模型用于预测三阴性乳腺癌的预后。
IF 3.9 4区 生物学 Q1 GENETICS & HEREDITY
Functional & Integrative Genomics
Pub Date : 2024-05-13 DOI: 10.1007/s10142-024-01370-7
Tiancheng Li, Siqi Chen, Yuqi Zhang, Qianqian Zhao, Kai Ma, Xiwei Jiang, Rongwu Xiang, Fei Zhai, Guixia Ling
{"title":"Retraction Note: Ensemble learning-based gene signature and risk model for predicting prognosis of triple-negative breast cancer","authors":"Tiancheng Li,&nbsp;Siqi Chen,&nbsp;Yuqi Zhang,&nbsp;Qianqian Zhao,&nbsp;Kai Ma,&nbsp;Xiwei Jiang,&nbsp;Rongwu Xiang,&nbsp;Fei Zhai,&nbsp;Guixia Ling","doi":"10.1007/s10142-024-01370-7","DOIUrl":"10.1007/s10142-024-01370-7","url":null,"abstract":"","PeriodicalId":574,"journal":{"name":"Functional & Integrative Genomics","volume":null,"pages":null},"PeriodicalIF":3.9,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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