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[Hokkaido igaku zasshi] The Hokkaido journal of medical science最新文献

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[Evaluation of the mucosa in the background of the lesion of colonic cancer]. 【结肠癌病变背景下粘膜的评价】。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-09-01
Yasuaki Mori
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引用次数: 0
[Study on arachidonic acid metabolism and collagen production in keloids]. 瘢痕疙瘩中花生四烯酸代谢和胶原蛋白生成的研究
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-09-01
Toshihiko Hayashi
{"title":"[Study on arachidonic acid metabolism and collagen production in keloids].","authors":"Toshihiko Hayashi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6338,"journal":{"name":"[Hokkaido igaku zasshi] The Hokkaido journal of medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26357502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The role of HOX gene in differentiation of GOTO cells of neuroblastoma]. [HOX基因在神经母细胞瘤GOTO细胞分化中的作用]。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-09-01
Shiulu Chang
{"title":"[The role of HOX gene in differentiation of GOTO cells of neuroblastoma].","authors":"Shiulu Chang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6338,"journal":{"name":"[Hokkaido igaku zasshi] The Hokkaido journal of medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26357507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Problems in applying a rapid assay kit for cardiac troponin T to medico-legal blood samples]. 心脏肌钙蛋白T快速检测试剂盒用于医学合法血液样本的问题
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-09-01
Kotaro Matoba, Koichi Terazawa, Satoshi Watanabe, Naoya Yamada, Mayumi Ueda

It is difficult to diagnose cardiac-related death only by external examination. However, in the areas where no medical examiner system is established, the diagnosis is made mostly from the findings by external examination. Clinically, cardiac troponin T (cTnT) rapid assay kits are used for the diagnosis of ischemic heart disease. The kits have started being applied to forensic medicine and used for the diagnosis of cardiac-related death without exact evidence. In this study, we collected postmortem blood samples from 110 forensic autopsy cases and evaluated the utility of the kits in the field of forensic medicine. Blood samples collected from the left and the right parts of the hearts showed extremely high positive rates (95.1% each), and peripheral blood samples also showed very high positive rates (71.2%), although cardiac-related deaths were only 7 cases of all 110 cases. Because cTnT concentration of postmortem blood samples is affected by non-cardiac-related natural death, postmortem changes, or cardiopulmonary resuscitation, the results from using the kits are not reliable in determining the cause of death. We conclude that the kits cannot be applied in forensic medicine.

仅靠外部检查很难诊断心源性死亡。然而，在没有建立法医制度的地区，诊断主要是根据外部检查的结果作出的。临床上，心肌肌钙蛋白T (cTnT)快速检测试剂盒用于缺血性心脏病的诊断。这些工具包已开始应用于法医学，并用于在没有确切证据的情况下诊断与心脏有关的死亡。在这项研究中，我们收集了110例法医尸检病例的死后血液样本，并评估了这些试剂盒在法医学领域的实用性。左、右心脏血样阳性率极高(分别为95.1%)，外周血标本阳性率也很高(71.2%)，但110例患者中心脏相关死亡仅7例。由于死后血液样本的cTnT浓度受非心脏相关的自然死亡、死后变化或心肺复苏的影响，使用试剂盒的结果在确定死亡原因方面不可靠。我们的结论是，这些工具包不能用于法医学。
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引用次数: 0
[Structure and function of a regulatory factor (cartregulin)for carnitine transport OCTN2]. [肉毒碱转运调节因子(cartregulin) OCTN2的结构和功能]。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-09-01
Kazuhiko Nagai
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引用次数: 0
[Cloning of rabbit sulfotransferase SULT2B1 and analysis of its specificity]. [兔硫转移酶SULT2B1的克隆及特异性分析]。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-09-01
Tazu Tahara
{"title":"[Cloning of rabbit sulfotransferase SULT2B1 and analysis of its specificity].","authors":"Tazu Tahara","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6338,"journal":{"name":"[Hokkaido igaku zasshi] The Hokkaido journal of medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26357504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyoderma gangrenosum complicated with myelodysplastic syndrome followed by rapidly progressing pyothorax-associated lymphoma: a case report. 坏疽性脓皮病合并骨髓增生异常综合征并发快速进展的脓胸相关淋巴瘤1例报告。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-07-01
Akiko Goto, Satoshi Yamamoto, Atsushi Notoya, Akio Takada, Masaya Mukai

This report describes a patient with pyoderma gangrenosum (PG) complicated with myelodysplastic syndrome (MDS) followed by rapidly progressing pyothorax-associated lymphoma (PAL). A 74-year-old man was admitted with cutaneous gangrene associated with MDS. We diagnosed him as having PG, and high-dose oral prednisolone was started. Two months after admission he developed lymphoma rapidly. The patient died in spite of radiation therapy. On autopsy, the pathological diagnosis was diffuse large cell lymphoma. Epstein-Barr virus (EBV)-encoded RNA, and EBV-encoded nuclear antigen (EBNA) were detected in lymphoma cells. This case suggested that immunosuppressive therapy might favour the clonal proliferation of EBV-infected cells.

本报告描述了一例坏疽性脓皮病(PG)并发骨髓增生异常综合征(MDS)，随后迅速进展的脓胸相关淋巴瘤(PAL)。一名74岁男性因与MDS相关的皮肤坏疽入院。我们诊断他患有PG，并开始大剂量口服强的松龙。入院两个月后，他迅速发展为淋巴瘤。尽管接受了放射治疗，病人还是死了。尸检病理诊断为弥漫性大细胞淋巴瘤。在淋巴瘤细胞中检测eb病毒(EBV)编码RNA和eb病毒编码核抗原(EBNA)。该病例提示免疫抑制治疗可能有利于ebv感染细胞的克隆增殖。
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引用次数: 0
[Estimation of time of death by the use of the overwintering of flies]. [利用苍蝇越冬来估计死亡时间]。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-07-01
Koichi Terazawa, Kotaro Matoba, Naoya Watanabe, Satoshi Watanabe, Naoya Yamada

We observed whether or not there were eggs, larvae, pupae, and empty pupal shells of flies on cadavers found outdoors in Sapporo, the northern district of Japan (43 degrees N). The temperature has an influence on the oviposition of flies. The average season in which flies lay eggs is from the middle of April to the beginning of November, although there is a little lag year by year. As flies overwinter generally as larvae, we can estimate postmortem interval of a cadaver found in spring on the basis of the size and the mortality of the larvae. If the length of larvae is 1 cm or longer, and many of them are dead, and if there are no empty pupal shells, the time of death of a cadaver found outdoors in spring is between the middle of September and the beginning of November in the previous year.

我们在日本北部地区札幌(北纬43度)的户外发现的尸体上观察了是否有蝇卵、幼虫、蛹和空蛹壳。温度对蝇的产卵有影响。苍蝇产卵的平均季节是从4月中旬到11月初，尽管每年都有一点滞后。蝇类一般以幼虫的形式越冬，根据幼虫的大小和死亡率，可以估计春季发现的尸体的死后时间。如果幼虫的长度在1厘米以上，而且很多已经死亡，如果没有空蛹壳，那么春天在户外发现的尸体的死亡时间是在前一年的9月中旬到11月初之间。
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引用次数: 0
[Effects of co-administration of CTLA4-Ig and ICOS-Ig for complex homologous transplantation in rats]. [CTLA4-Ig和ICOS-Ig共同给药对大鼠复杂同源移植的影响]。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-05-01
Masahiro Nagai
{"title":"[Effects of co-administration of CTLA4-Ig and ICOS-Ig for complex homologous transplantation in rats].","authors":"Masahiro Nagai","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6338,"journal":{"name":"[Hokkaido igaku zasshi] The Hokkaido journal of medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26084378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Novel gene therapy for epidermolysis bullosa using recombinant human VII-type collagen protein]. [重组人vii型胶原蛋白治疗大疱性表皮松解症的新基因疗法]。
[Hokkaido igaku zasshi] The Hokkaido journal of medical science
Pub Date : 2006-05-01
Masataka Abe
{"title":"[Novel gene therapy for epidermolysis bullosa using recombinant human VII-type collagen protein].","authors":"Masataka Abe","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":6338,"journal":{"name":"[Hokkaido igaku zasshi] The Hokkaido journal of medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2006-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26084380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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