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Anesthesia for Placement of a Paracorporeal Lung Assist Device and Subsequent Heart-Lung Transplantation in a Child with Suprasystemic Pulmonary Hypertension and End-Stage Respiratory Failure. 1例伴有超系统肺动脉高压和终末期呼吸衰竭的儿童在麻醉下放置辅助肺装置和随后的心肺移植。
Pub Date : 2016-05-15 DOI: 10.1213/XAA.0000000000000300
Danton Char, V. Yarlagadda, K. Maeda, Glyn Williams
Pediatric patients with end-stage respiratory failure and pulmonary hypertension traditionally have poor outcomes when bridged with extracorporeal membrane oxygenation to lung or heart-lung transplantation. Therefore, several institutions have attempted paracorporeal lung assist devices as a bridge. However, given the small number of patients, little is known about approaches to anesthetic induction in these hemodynamically unstable patients either before placement of a device or anesthetic induction once a device is in situ. In this case report, we describe our anesthetic experience managing a 13-year-old boy for both paracorporeal lung assist device placement and subsequent heart-lung transplantation.
终末期呼吸衰竭和肺动脉高压的儿科患者传统上通过体外膜氧合进行肺或心肺移植的预后较差。因此,一些机构已经尝试了辅助辅助装置作为桥梁。然而,由于患者数量较少,对于这些血流动力学不稳定的患者,无论是在植入装置之前还是在植入装置后,麻醉诱导的方法都知之甚少。在这个病例报告中,我们描述了我们治疗一个13岁男孩的麻醉经验,包括辅助辅助装置放置和随后的心肺移植。
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引用次数: 1
Acute Hypotension After 50% Dextrose Injections. 50%葡萄糖注射后急性低血压。
Pub Date : 2016-05-15 DOI: 10.1213/XAA.0000000000000299
V. Saites, K. Laudanski
The hemodynamic effects of small-volume boluses of hyperosmotic solutions are often deemed negligible in the clinical setting. However, animal studies have reported decreases in systemic arterial blood pressure and bradycardia with the administration of hyperosmotic solutions. This is a report of a 60-year-old woman, intubated and sedated, who developed acute decreases in systemic arterial blood pressure with the administration of ≤50 mL of 50% dextrose. Animal studies suggest that hyperosmolar-induced hypotension may be avoided by administering the hyperosmotic solution slowly. This allows for admixture and therefore a decreased osmotic load at the proposed osmoreceptor involved in the neural reflex.
在临床上,小体积高渗溶液的血流动力学作用通常被认为可以忽略不计。然而,动物研究表明,高渗溶液可降低全身动脉血压和心动过缓。这是一个60岁的妇女,插管和镇静,谁出现急性全身动脉血压下降,给予≤50ml的50%葡萄糖。动物研究表明,通过缓慢施用高渗溶液可以避免高渗引起的低血压。这允许混合物,因此减少渗透负荷在提议的渗透受体参与神经反射。
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引用次数: 1
Difficult Ventilation After Successful Intubation in the Emergency Setting due to a Ball Valve Clot. 在紧急情况下由于球阀凝块插管成功后难以通气。
Pub Date : 2016-05-15 DOI: 10.1213/XAA.0000000000000294
Justin S. Liberman, Wade A Weigel, J. Neal
The inability to ventilate a patient after successful intubation is a rare but emergent situation and may be caused by obstruction of the endotracheal tube, bilateral tension pneumothorax, esophageal intubation, severe bronchospasm, or mainstem bronchus intubation. We describe an increase in mean airway pressure, inability to ventilate, and loss of cardiac output secondary to a blood clot acting as a ball valve at the end of an endotracheal tube.
气管插管成功后患者无法通气是一种罕见但紧急的情况,可能由气管插管阻塞、双侧张力性气胸、食管插管、严重支气管痉挛或主支气管插管引起。我们描述了平均气道压力增加,无法通气,心输出量减少,继发于气管内管末端的血凝块作为球阀。
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引用次数: 1
Monitoring the Location of Staff via Mobile Devices in a Large Multifacility Practice Group. 通过移动设备监控大型多设施实践小组中员工的位置。
Pub Date : 2016-05-15 DOI: 10.1213/XAA.0000000000000288
C. W. Connor, Michael Herzig
We describe a novel location and timekeeping system for a large, multifacility practice group using an app installed on mobile devices belonging to the staff. The system can be used independently of physical time clocks and without extracting information from anesthesia information management systems. The app creates geofences, reporting automatically when the user enters or departs the vicinity of a facility. The app displays the location of staff at all facilities, providing situational awareness. The leaving order of staff was adjusted daily using app data for the previous workload. This was successful; overtime was more evenly distributed year on year. Acceptance of the system was excellent.
我们使用安装在员工移动设备上的应用程序,为一个大型、多设施的实践小组描述了一种新的定位和计时系统。该系统可以独立于物理时钟使用,无需从麻醉信息管理系统中提取信息。该应用程序创建地理围栏,当用户进入或离开设施附近时自动报告。该应用程序显示所有设施中工作人员的位置,提供态势感知。每天根据之前工作量的app数据调整员工离职顺序。这是成功的;加班时间每年的分布更为均匀。系统的接受度非常好。
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引用次数: 3
Identification and Treatment of New Inflammatory Triggers for Complex Regional Pain Syndrome: Small Intestinal Bacterial Overgrowth and Obstructive Sleep Apnea. 复杂局部疼痛综合征的新炎症诱因的识别和治疗:小肠细菌过度生长和阻塞性睡眠呼吸暂停。
Pub Date : 2016-05-01 DOI: 10.1213/XAA.0000000000000292
L. Weinstock, Trisha L Myers, A. Walters, Oscar A Schwartz, J. Younger, P. Chopra, A. Guarino
Complex regional pain syndrome (CRPS) is evoked by conditions that may be associated with local and/or systemic inflammation. We present a case of long-standing CRPS in a patient with Ehlers-Danlos syndrome in which prolonged remission was attained by directing therapy toward concomitant small intestinal bacterial overgrowth, obstructive sleep apnea, and potential increased microglia activity. We theorize that cytokine production produced by small intestinal bacterial overgrowth and obstructive sleep apnea may act as stimuli for ongoing CRPS symptoms. CRPS may also benefit from the properties of low-dose naltrexone that blocks microglia Toll-like receptors and induces production of endorphins that regulate and reduce inflammation.
复杂区域疼痛综合征(CRPS)是由可能与局部和/或全身性炎症相关的条件引起的。我们报告了一例ehers - danlos综合征患者的长期CRPS,通过指导治疗伴随的小肠细菌过度生长,阻塞性睡眠呼吸暂停和潜在的小胶质细胞活性增加,延长了缓解期。我们推测,小肠细菌过度生长和阻塞性睡眠呼吸暂停产生的细胞因子可能是持续的CRPS症状的刺激因素。CRPS也可能受益于低剂量纳曲酮的特性,它可以阻断小胶质细胞toll样受体,诱导内啡肽的产生,从而调节和减少炎症。
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引用次数: 15
Postoperative Epidural Abscess in an Infant. 1例婴儿术后硬膜外脓肿。
Pub Date : 2016-05-01 DOI: 10.1213/XAA.0000000000000296
A. Suchar, A. Bailey, V. Kopp
In the pediatric population, development of an abscess after epidural analgesia is a rare event. We report who is believed to be the youngest patient with development of an epidural abscess secondary to epidural catheter placement. We detail the infant's symptoms, radiographic workup, surgical treatment, and follow-up.
在儿科人群中,硬膜外镇痛后脓肿的发展是一个罕见的事件。我们报告谁被认为是最年轻的病人发展硬膜外脓肿继发硬膜外导管置入。我们详细介绍婴儿的症状、影像学检查、手术治疗和随访。
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引用次数: 1
Prophylactic Antibiotic Management of Surgical Patients Noted as "Allergic" to Penicillin at Two Academic Hospitals. 两所专科医院青霉素“过敏”手术患者的预防性抗生素管理
Pub Date : 2016-05-01 DOI: 10.1213/XAA.0000000000000253
R. Epstein, P. S. Jacques, J. Wanderer, Mark R Bombulie, N. Agarwalla
We studied prophylactic antibiotics administered at 2 academic medical centers during a 6-year period where a cephalosporin was indicated but an "allergy" to penicillin was noted. Another drug (typically vancomycin or clindamycin) was substituted approximately 80% of the time; this occurred frequently even when symptoms unrelated to acute hypersensitivity were listed. In >50% of cases, the reaction was either omitted or vague (e.g., simply "rash"). Given the estimated 1% cross-reactivity between penicillins and cephalosporins with similar R1 side chains, many of these patients could have received either the prescribed cephalosporin or another cephalosporin with a different R1 side chain.
我们研究了2个学术医疗中心在6年期间使用的预防性抗生素,其中指出了头孢菌素,但注意到对青霉素“过敏”。另一种药物(通常是万古霉素或克林霉素)约80%的时间被替代;即使列出与急性过敏无关的症状,这种情况也经常发生。在超过50%的病例中,反应要么被省略,要么含糊不清(例如,简单地“皮疹”)。考虑到青霉素类药物与具有相似R1侧链的头孢菌素之间估计有1%的交叉反应性,这些患者中的许多人可能服用了处方头孢菌素或具有不同R1侧链的另一种头孢菌素。
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引用次数: 15
Bilateral Dilated Nonreactive Pupils in a Neonate After Surgery. 新生儿术后双侧无反应瞳孔扩大一例。
Pub Date : 2016-05-01 DOI: 10.1213/XAA.0000000000000306
Christine L. Joyce, B. Greenwald, Peggy Han
Fixed and dilated pupils are disturbing when encountered during a physical examination in the pediatric intensive care unit, particularly when sedation or neuromuscular blockade confounds the neurologic examination. Rocuronium, a nondepolarizing neuromuscular drug, does not cross the blood-brain barrier and is not considered a causative agent for fixed mydriasis. We report a case of bilateral fixed and dilated pupils in a 1-week-old low-birth-weight neonate, which we contend was secondary to centrally mediated neuromuscular blockade.
在儿童重症监护病房的体格检查中发现固定瞳孔和放大瞳孔是令人不安的,特别是当镇静或神经肌肉阻滞混淆了神经系统检查时。罗库溴铵是一种非去极化神经肌肉药物,不能穿过血脑屏障,不被认为是固定瞳孔的病原体。我们报告一例双侧固定和扩大的瞳孔在一个1周大的低出生体重新生儿,我们认为这是继发于中央介导的神经肌肉封锁。
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引用次数: 7
Ultrasound-Guided Serratus Anterior Plane Block in Breast Reconstruction Surgery. 超声引导下锯肌前平面阻滞在乳房重建手术中的应用。
Pub Date : 2016-05-01 DOI: 10.1213/XAA.0000000000000297
R. Khemka, A. Chakraborty, R. Ahmed, Taniya Datta, S. Agarwal
Pecs block and its variations have been used for various breast surgeries. We describe 2 cases of mastectomy and breast reconstruction by latissimus dorsi (LD) flap where regional analgesia was provided by a combination of ultrasound-guided Pecs-I block and serratus anterior plane block, a recently described technique in which local anesthetic is deposited in the plane between the LD and serratus anterior muscle. This resulted in excellent intraoperative and postoperative analgesia and a minimum of systemic analgesics. The described technique is safe to administer and provides good analgesia for breast reconstruction surgery by LD flap.
胸肌块及其变体已用于各种乳房手术。我们描述了2例通过背阔肌(LD)皮瓣进行乳房切除术和乳房重建的病例,其中通过超声引导的Pecs-I阻滞和前锯肌平面阻滞联合提供区域镇痛,这是一种最近描述的技术,局部麻醉剂沉积在背阔肌和前锯肌之间的平面上。这导致了良好的术中和术后镇痛和最小的全身镇痛。所述的技术是安全的管理和提供良好的镇痛乳房再造手术的LD瓣。
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引用次数: 33
Simulation Manikin Modifications for High-Fidelity Training of Advanced Airway Procedures. 高级气道手术高保真训练的模拟人体修改。
Pub Date : 2016-05-01 DOI: 10.1213/XAA.0000000000000278
Jan Hirsch, J. Generoso, R. Latoures, Y. Acar, R. Fidler
Thoracic anesthesia procedures are challenging to master during anesthesia training. A Laerdal ALS Simulator® manikin was modified by adding a bronchial tree module to create fidelity to the fourth generation. After modification, placement of endotracheal tubes up to 8.0 mm is possible by direct laryngoscopy, video laryngoscopy, and fiberoptically; in addition, it allows fiberoptically guided insertion of endobronchial blockers. Insertion of left and right 35-Fr double-lumen tubes permits double- and single-lung ventilation with continuous positive airway pressure and positive end-expiratory pressure. This anatomical modification created a high-fidelity training tool for thoracic anesthesia that has been incorporated into educational curricula for anesthesia.
在麻醉训练中,胸麻程序是很难掌握的。通过添加支气管树模块来修改Laerdal ALS模拟器®人体模型,以创建对第四代的保真度。改良后,可通过直接喉镜、视频喉镜和纤维光学放置长达8.0 mm的气管内管;此外,它允许光纤引导支气管内阻滞剂的插入。左侧和右侧35-Fr双腔管的插入允许双肺和单肺通气,持续气道正压和呼气末正压。这种解剖修改创造了一个高保真的胸麻醉训练工具,已被纳入麻醉教育课程。
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引用次数: 3
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A&A Case Reports
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