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A.M.A. archives of internal medicine最新文献

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Nodular goiter. Incidence, morphology before and after iodine prophylaxis, and clinical diagnosis. 结节性甲状腺肿。发病率、碘预防前后形态及临床诊断。
Pub Date : 1960-07-01 DOI: 10.1001/archinte.1960.03820010012004
R P STOFFER, J W WELCH, C A HELLWIG, V E CHESKY, E N McCUSKER
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引用次数: 56
Master Your Tensions and Enjoy Living Again. 控制你的紧张,重新享受生活。
Pub Date : 1960-06-01 DOI: 10.1001/ARCHINTE.1960.00270180156026
D. B. Stone
Nor or Never: The Promise of the Middle Years. By Smiley Blanton, M.D. Price, $4.95. Pp. 273. Prentice-Hall, Inc., Route 9W, Englewood Cliffs, N.J., 1959. I have always regarded the cave, the fire, and the hunk of meat the rock bottom of human existence. Our technological obsession, our machines, and our economic philosophy have produced the highest general standard of living in the history of the world. Whether we like it or not, this is the age of know-how. Nevertheless, our culture may defeat us. If the cold war warms, the exploitation of science may kill us all. We may emphasize a standard of living as an end in itself. We may deceive ourselves that opulence alone can solve personal, technical, and political conundrums: insecurity and boredom; disease; rocketry; population expansion, and international envy. Materialism is reputed to favor a loss of ethical and cultural values, and this may make
要么不做,要么不做:中年的承诺。斯迈利·布兰顿,医学博士著,普莱斯,4.95美元。273页。普伦蒂斯-霍尔公司,9W公路,恩格尔伍德悬崖,新泽西州,1959年。我一直把洞穴、火和那大块肉看作是人类生活的最底层。我们对技术的痴迷、我们的机器和我们的经济哲学创造了世界历史上最高的总体生活水平。不管我们喜欢与否,这是一个技术诀窍的时代。然而,我们的文化可能会打败我们。如果冷战变暖,对科学的利用可能会杀死我们所有人。我们可以强调生活水平本身就是目的。我们可能会欺骗自己,认为只有富裕才能解决个人、技术和政治难题:不安全感和无聊;疾病;火箭;人口扩张和国际羡慕。唯物主义被认为会导致道德和文化价值的丧失,这可能会导致
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引用次数: 0
The Case for Basic Education. 基础教育的案例。
Pub Date : 1960-05-01 DOI: 10.1001/ARCHINTE.1960.00270170155017
W. Bean
Despite the fact that the launching of sputniks by Russia threw the country at large, and educators in particular, into a spasm of extensive proportions, the period of agonizing reappraisal has been largely that of offering lip service, not always very consistent or clear, to one or another of the several philosophies of contemporary education. This book was published under the aegis of the Council for Basic Education in Washington, D.C., a sound and constructive organization dealing with problems in education. They publish a monthly news letter, but this is their first book. Its subject is a program of aims for public schools presented as a statement by eighteen scholars, distinguished in various fields, who come to grips with the realities of basic education. They emphasize their ideas of what a student should have gained after twelve years of public schooling. The book deals with principles rather than details. It
尽管俄罗斯发射的人造卫星使整个国家,尤其是教育工作者,陷入了一场大范围的痉挛,但这段痛苦的重新评估时期,主要是对当代教育的几种哲学中的一种或另一种提供口头支持的时期,这种支持并不总是非常一致或明确。这本书是在华盛顿特区基础教育委员会的支持下出版的,这是一个处理教育问题的健全和建设性的组织。他们每月出版一份新闻通讯,但这是他们的第一本书。它的主题是一个公立学校的目标计划,由18位不同领域的杰出学者提出,他们着手处理基础教育的现实。他们强调学生在12年的公立学校教育后应该获得什么。这本书讲的是原则而不是细节。它
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引用次数: 12
Enzymes of Polynucleotide Metabolism. 多核苷酸代谢酶。
Pub Date : 1960-04-01 DOI: 10.1001/ARCHINTE.1960.00270160159024
R. Vilter
This volume includes discussions not only of the enzymes of polynucleotide metabolism and their structure and function but also discussions of the structure and properties of synthetic and other polynucleotides. The papers are highly technical and will prove to be excellent source material for anyone interested in the complicated details of polynucleotide metabolism. Since this is the basic chemistry of the gene and is responsible for the transmission of hereditary characteristics, it is an extremely important biochemical area. This is not a book which is easily read or understood by the average physician or by the physician with a smattering of knowledge of the biochemistry of nucleic acids. It is written by and for the Ph.D.'s in biochemistry who have specialized in nucleic acid metabolism. However, physicians interested in research in these areas will find stimulating material in these chapters, which present not only that which is known but that
本卷不仅包括多核苷酸代谢酶及其结构和功能的讨论,还包括合成和其他多核苷酸的结构和性质的讨论。这些论文技术性很强,对于任何对多核苷酸代谢的复杂细节感兴趣的人来说,都是极好的来源材料。由于这是基因的基本化学,并负责遗传特征的传递,因此它是一个极其重要的生化领域。这不是一本普通医生或对核酸生物化学稍有了解的医生容易阅读或理解的书。它是由专门研究核酸代谢的生物化学博士撰写的。然而,对这些领域的研究感兴趣的医生将在这些章节中找到令人兴奋的材料,这些章节不仅介绍了已知的内容,而且介绍了已知的内容
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引用次数: 1
Sickle-Cell Disease: The Aplastic Crisis and Erythroid Maturation Defect Occurring Simultaneously in Three Members of a Family 镰状细胞病:在一个家庭的三个成员中同时发生的再生危象和红细胞成熟缺陷
Pub Date : 1960-01-01 DOI: 10.1001/ARCHINTE.1960.00270130092011
G. Hilkovitz
It is now recognized that bone-marrow failure rather than hyperhemolysis underlies the crises in sickle-cell disease.1,2Bonemarrow failure has been reported in Cooley's hemolytic anemia,3hereditary spherocytosis,4and paroxysmal nocturnal hemoglobinuria.5Maturation arrest of the neutrophil polymorphonuclear leukocytes has been noted in sickle-cell disease.6Infection has been thought to precipitate bone-marrow aplasia in sickle-cell disease1,2and in hereditary spherocytosis.7The occurrence of "aplastic crisis" in several members of a family has been recorded in hereditary spherocytosis7and in sickle-cell disease.17Erythroblastopenia has been noted during the course of viral pneumonia in patients without hemolytic blood diseases,8and the same communication records eosinophilia in patients who had erythrocytic aplasia after exposure to allergens. The association of chronic hemolytic anemias with megaloblastic arrest of the bone marrow has been documented. Some of these responded to vitamin B12therapy,9some were associated with pregnancy,10and in others dietary deficiency of folie acid
现在人们认识到,镰状细胞病的危险是骨髓衰竭而不是高溶血。骨髓功能衰竭在Cooley's溶血性贫血,3遗传性球形红细胞增多症,4和阵发性夜间血红蛋白尿中都有报道。中性粒细胞多形核白细胞成熟阻滞已在镰状细胞病中被注意到。感染被认为是镰状细胞病和遗传性球形细胞增多症患者骨髓发育不全的原因。在遗传性球形红细胞增多症和镰状细胞病中,一个家族中几个成员出现“再生危机”的记录是有的。17在没有溶血性血液病的病毒性肺炎患者中发现了红细胞减少,8在接触过敏原后出现红细胞发育不全的患者中也发现了嗜酸性粒细胞增多。慢性溶血性贫血与骨髓巨幼细胞骤停的关系已被证实。其中一些人对维生素b12治疗有反应,一些人与怀孕有关,10还有一些人缺乏叶酸
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引用次数: 10
The Year Book of Endocrinology (1958-1959 Year Book Series). 内分泌学年鉴(1958-1959年年鉴系列)。
Pub Date : 1959-12-01 DOI: 10.1001/ARCHINTE.1959.00270120209025
D. B. Stone
Twelve months ago, Gordan wrote this in his introduction to the 1957-1958 volume. "It is the intention of this volume to depict the endocrine literature, albeit in miniature. The articles selected for abstracting and presentation have been chosen because, in the opinion of your editor, they represent what is being reported. This is not a text book of endocrinology, and this year's literature does not necessarily cover every pertinent field, for which the interested reader is referred to one of the numerous excellent texts published in the past few years. Parenthetically, let me add that a particular effort is made to search out those articles which are not generally available in the Journals received by most American physicians.... Pertinent articles in all languages can be and are considered for inclusion here." Gordan has succeeded annually, and the current Year Book of Endocrinology is of the highest quality. It is recommended
12个月前,戈登在1957-1958年卷的引言中写道。“这本书的目的是描绘内分泌文献,尽管是缩微的。选择摘要和展示的文章是因为,在你的编辑看来,它们代表了正在报道的内容。这不是一本内分泌学的教科书,今年的文献不一定涵盖每个相关领域,对此感兴趣的读者可以参考过去几年出版的众多优秀文本之一。顺便说一句,让我补充一下,我们做出了特别的努力来搜索那些在大多数美国医生收到的期刊上通常找不到的文章....所有语文的相关文章都可以而且正在考虑列入这里。”戈登每年都取得了成功,目前的《内分泌学年鉴》质量最高。这是推荐的
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引用次数: 0
Ciba Foundation Symposium on the Regulation of Cell Metabolism. 汽巴基金会细胞代谢调节学术研讨会。
Pub Date : 1959-12-01 DOI: 10.1001/ARCHINTE.1959.00270120209026
R. Marshall
The symposium that constitutes this edition deals primarily, but not exclusively, with "primitive" control mechanisms of the cell. Hormonal influences are not extensively treated. Sixteen papers and discussions by prominent research workers are presented at the biochemical level, describing many ideas and problems on the regulation of cell metabolism. Among the substances and mechanisms considered in the papers as playing a regulatory role in cell metabolism are the intracellular concentration of inorganic phosphorus, adenosinediphosphate, enzyme concentration, electron transport, coenzymes, and a "feed-back" concept. This book is by experts, primarily for experts, in this field.
构成这一版本的专题讨论会主要讨论细胞的“原始”控制机制,但不是唯一的。荷尔蒙的影响并没有得到广泛的治疗。从生物化学层面介绍了16篇杰出研究工作者的论文和讨论,描述了许多关于细胞代谢调节的观点和问题。在这些论文中考虑的在细胞代谢中发挥调节作用的物质和机制包括细胞内无机磷浓度、二磷酸腺苷、酶浓度、电子传递、辅酶和“反馈”概念。这本书是由专家撰写的,主要是为这个领域的专家编写的。
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引用次数: 2
Idiopathic paroxysmal myoglobinuria. Report of a case with Med 特发性阵发性肌红蛋白尿。报告一名医务人员的病例
Pub Date : 1959-10-01 DOI: 10.1001/archinte.1959.00270100114020
J JAVID, H I HOROWITZ, A R SANDERS, T H SPAET
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引用次数: 12
Birth of Normal Babies. 正常婴儿的出生。
Pub Date : 1959-09-01 DOI: 10.1001/ARCHINTE.1959.00270090165031
W. C. Keetel
In this book the author attempts to prove that the majority of congenital defects and defective babies can be attributed to the occurrence of stress in one form or the other occurring during the first three months of pregnancy. He offers sixty illustrations of various forms of emotional stress that have allegedly resulted in congenital abnormalities. The author gives examples of excessive pressure on the stomach producing a cleft palate, psoriasis producing a cleft palate, and penicillin rash producing a moron. There are ten things that the author emphasizes that either should be avoided in pregnancy or should be done. These are as follows: Stress should be avoided. No surgical procedures should be performed during pregnancy except emergency surgery. All x-rays and general anesthesia should be avoided. Potent drugs should be avoided, as well as high-altitude flying. If the patient is exposed to any communicable diseases, γ-globulin should be administered.
在这本书中,作者试图证明,大多数先天性缺陷和有缺陷的婴儿可以归因于在怀孕的前三个月以一种形式或另一种形式出现的压力。他提供了60个不同形式的情绪压力的例子,据称这些情绪压力导致了先天性异常。作者给出了胃压力过大导致腭裂的例子,牛皮癣导致腭裂的例子,青霉素皮疹导致白痴的例子。作者强调了怀孕期间应该避免或应该做的十件事。这些建议如下:应避免压力。除紧急手术外,怀孕期间不应进行任何外科手术。应避免所有x光和全身麻醉。应该避免强效药物,以及高空飞行。如果患者暴露于任何传染病,应给予γ-球蛋白。
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引用次数: 0
A Symposium on the Evaluation of Drug Toxicity. 药物毒性评价研讨会。
Pub Date : 1959-09-01 DOI: 10.1001/ARCHINTE.1959.00270090162024
L. Lasagna
This is a refreshing book. The formal presentations are for the most part unhackneyed, and the discussions are lively and thoughtful. I found the chapter by Hurst on sexual differences in toxicity of drugs and the one by Paget on the morphological evaluation of toxic action particularly stimulating. (Paget's "routine" histopathology looks fantastically complete, by comparison with American standards!) John Litchfield, the only American at the meeting, supplies another high spot with his thoughtful, off-beat analysis of "screening" for efficacy and toxicity. The volume is also pleasantly brief and can be held comfortably in one hand while one is lying in bed. It is recommended to pharmacologists and to those clinicians concerned with the investigation of new drugs.
这是一本令人耳目一新的书。正式的演讲在很大程度上是不陈腐的,讨论是生动和深思熟虑的。我发现赫斯特关于药物毒性的性别差异的那一章和佩吉特关于毒性作用的形态学评价的那一章特别令人兴奋。(与美国标准相比,佩吉特的“常规”组织病理学检查看起来非常完整!)会议上唯一的美国人约翰•利奇菲尔德(John Litchfield)提出了另一个亮点,他对“筛选”疗效和毒性进行了深思熟虑、与众不同的分析。体积也很简单,当一个人躺在床上时,可以舒适地拿在一只手上。它被推荐给药理学家和那些与新药研究有关的临床医生。
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引用次数: 0
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A.M.A. archives of internal medicine
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