The pollution status of Lagos Lagoon was investigated to determine some physical and chemical parameters, in order to further understand its water quality. Five locations were selected according to the anthropogenic activities taking place in the areas. The measured parameters are water temperature, salinity, conductivity, pH, dissolved oxygen (DO) and alkalinity. The mean values ranged from 28.50-30.15°C for temperature, 7.86-8.50 for pH, ND-10.60‰ for salinity, 0.18-15.20µS/cm for electrical conductivity, 12.00-14.00 mg/l for alkalinity and 1.60-6.40 mg/l for dissolved oxygen. The statistical analysis of the measured physicochemical parameters revealed non-significant difference (p>0.05) across all stations in the physico-chemical parameters. Generally, the values obtained suggest the influence of anthropogenic activities especially the depletion of DO in most of the stations. Therefore, point source and non-point source pollution into the Lagos Lagoon should be controlled for the health and safety of the aquatic ecosystems. Generally, all the measured parameters were either below or within the permissible limits obtainable in the marine environment.
{"title":"Assessment of Some Physico-Chemical Parameters of Lagos Lagoon, Southwestern Nigeria","authors":"P. Oyeleke, S. Popoola, O. A. Abiodun","doi":"10.32861/ajc.43.09.11","DOIUrl":"https://doi.org/10.32861/ajc.43.09.11","url":null,"abstract":"The pollution status of Lagos Lagoon was investigated to determine some physical and chemical parameters, in order to further understand its water quality. Five locations were selected according to the anthropogenic activities taking place in the areas. The measured parameters are water temperature, salinity, conductivity, pH, dissolved oxygen (DO) and alkalinity. The mean values ranged from 28.50-30.15°C for temperature, 7.86-8.50 for pH, ND-10.60‰ for salinity, 0.18-15.20µS/cm for electrical conductivity, 12.00-14.00 mg/l for alkalinity and 1.60-6.40 mg/l for dissolved oxygen. The statistical analysis of the measured physicochemical parameters revealed non-significant difference (p>0.05) across all stations in the physico-chemical parameters. Generally, the values obtained suggest the influence of anthropogenic activities especially the depletion of DO in most of the stations. Therefore, point source and non-point source pollution into the Lagos Lagoon should be controlled for the health and safety of the aquatic ecosystems. Generally, all the measured parameters were either below or within the permissible limits obtainable in the marine environment.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86962037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Phytochemicals with protein binding properties, active against snake envenomation such as flavonoids, polyphenols, saponins, tannins, terpenoids, xanthenes, quinonoids, steroids and alkaloids bind to toxic venom proteins thereby inactivating them. This research was aimed at isolating antisnake venom agents from Azadirachta indica leaf extracts using activity-guided isolation protocols. A. indica leaf was collected, authenticated and extracted using methanol followed by solvent-fractionation using hexane and ethylacetate. These fractions were further separated using column and thin-layer chromatography. The pooled chromatographic fractions were screened for the antivenom activity using Naja nigricollis venom phospholipase A2 (NVPLA2) inhibition assay and albino rat models. Polyvalent serum-based antivenin was used as standard. The column chromatography of the A. indica leaf hexane and ethylacetate extracts yielded sixty (60) and sixty nine (69) fractions. Based on similarities on the TLC profiles, fractions were pooled. Eleven (11) pooled hexane fractions (PHFs) and fourteen (14) pooled ethylacetate fractions (PEFs) were obtained. After antivenom activity screening, pooled hexane fraction 3 (PHF3) and pooled ethylacetate fraction 1B (PEF1B) from the hexane and ethylacetate fractions respectively protected envenomed albino rats from death at a dose of 20 mg/kg b.w. against 0.8 mg/kg b.w. of N. nigricollis venom. Hence, these findings suggest that the isolated active compounds can serve as leads for the development of safe, readily available and affordable plant-based antivenoms.
{"title":"Isolation of Antisnake Venom Agents from Azadirachta Indica (A. Juss) Leaf Extracts","authors":"I. Sani, R. Umar, S. Hassan, U. Faruq, F. Bello","doi":"10.32861/ajc.52.10.16","DOIUrl":"https://doi.org/10.32861/ajc.52.10.16","url":null,"abstract":"Phytochemicals with protein binding properties, active against snake envenomation such as flavonoids, polyphenols, saponins, tannins, terpenoids, xanthenes, quinonoids, steroids and alkaloids bind to toxic venom proteins thereby inactivating them. This research was aimed at isolating antisnake venom agents from Azadirachta indica leaf extracts using activity-guided isolation protocols. A. indica leaf was collected, authenticated and extracted using methanol followed by solvent-fractionation using hexane and ethylacetate. These fractions were further separated using column and thin-layer chromatography. The pooled chromatographic fractions were screened for the antivenom activity using Naja nigricollis venom phospholipase A2 (NVPLA2) inhibition assay and albino rat models. Polyvalent serum-based antivenin was used as standard. The column chromatography of the A. indica leaf hexane and ethylacetate extracts yielded sixty (60) and sixty nine (69) fractions. Based on similarities on the TLC profiles, fractions were pooled. Eleven (11) pooled hexane fractions (PHFs) and fourteen (14) pooled ethylacetate fractions (PEFs) were obtained. After antivenom activity screening, pooled hexane fraction 3 (PHF3) and pooled ethylacetate fraction 1B (PEF1B) from the hexane and ethylacetate fractions respectively protected envenomed albino rats from death at a dose of 20 mg/kg b.w. against 0.8 mg/kg b.w. of N. nigricollis venom. Hence, these findings suggest that the isolated active compounds can serve as leads for the development of safe, readily available and affordable plant-based antivenoms.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84147008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Naeem, Saqib Ali, S. Shahzadi, K. Ullah, S. Hussain, S. Ramzan, S. Kamal
The hydrated complexes 1, 3, 7 and 8 with the general formula (RCOO)2M.xH2O (where M = Zn & x = 6; M = Cu & x = 5,6) were synthesized by the reaction of sodium salt of 2,2`-diphenyl acetic acid or 2-(4-hydroxyphenyl)acetic acid (RCOONa) with Zn(NO3)2.6H2O or CuSO4.5H2O in an aqueous medium. The addition of methanolic solution of either bipyridine (bpy) or 1,10-phenanthroline (phen) to an aqueous suspension of 1, 3, 7 and 8 (produced in situ) result in the formation of mixed ligand products with the general formulae (RCOO)2M(bpy).xH2O (2, 4, 9 and 10) and (RCOO)2M(phen).xH2O (5 and 6). The complexes were characterized by microanalysis, FTIR and NMR (1H and 13C) spectroscopic techniques. The FTIR data suggested a bidentate coordination mode of the carboxylate ligand and complexes exhibited four/six-coordinated geometry in the solid state. The spectroscopic data also revealed the presence of coordinated water molecules in all complexes. 1H and 13C NMR data demonstrated the coordination between ligand and the metal in complex 1. The complexes were tested for their binding with salmon sperm DNA (SS-DNA). The DNA binding potential of the complexes owed to the presence of zinc metal and the nature of the incorporated ligand. The complexes showed a significant hypochromic effect and an intercalating mode of binding with SS-DNA. The complexes were screened against various bacterial and fungal strains to check their biological activity. All the complexes showed significant antibacterial activity but none of complex exhibit antifungal activity.
{"title":"Synthesis, Characterization and DNA Binding Studies of Zn(II)/Cu(II) Complexes with 2,2`-Diphenyl Acetic Acid/2-(4-Hydroxyphenyl)Acetic Acid Ligand Precursors and Nitrogen Bases","authors":"Muhammad Naeem, Saqib Ali, S. Shahzadi, K. Ullah, S. Hussain, S. Ramzan, S. Kamal","doi":"10.32861/ajc.51.1.9","DOIUrl":"https://doi.org/10.32861/ajc.51.1.9","url":null,"abstract":"The hydrated complexes 1, 3, 7 and 8 with the general formula (RCOO)2M.xH2O (where M = Zn & x = 6; M = Cu & x = 5,6) were synthesized by the reaction of sodium salt of 2,2`-diphenyl acetic acid or 2-(4-hydroxyphenyl)acetic acid (RCOONa) with Zn(NO3)2.6H2O or CuSO4.5H2O in an aqueous medium. The addition of methanolic solution of either bipyridine (bpy) or 1,10-phenanthroline (phen) to an aqueous suspension of 1, 3, 7 and 8 (produced in situ) result in the formation of mixed ligand products with the general formulae (RCOO)2M(bpy).xH2O (2, 4, 9 and 10) and (RCOO)2M(phen).xH2O (5 and 6). The complexes were characterized by microanalysis, FTIR and NMR (1H and 13C) spectroscopic techniques. The FTIR data suggested a bidentate coordination mode of the carboxylate ligand and complexes exhibited four/six-coordinated geometry in the solid state. The spectroscopic data also revealed the presence of coordinated water molecules in all complexes. 1H and 13C NMR data demonstrated the coordination between ligand and the metal in complex 1. The complexes were tested for their binding with salmon sperm DNA (SS-DNA). The DNA binding potential of the complexes owed to the presence of zinc metal and the nature of the incorporated ligand. The complexes showed a significant hypochromic effect and an intercalating mode of binding with SS-DNA. The complexes were screened against various bacterial and fungal strains to check their biological activity. All the complexes showed significant antibacterial activity but none of complex exhibit antifungal activity.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80149133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-15DOI: 10.32861/ajc.312.109-117
Y. Chauhan, S. Bhagat
This work is the diminutive attempt towards the plastic waste recycling conducted at Department of Plastic Engineering, Government Polytechnic, Miraj. The term ‘Polyfuel’ means the liquid fuel produced from waste plastics. We have performed the experiment for conversion of waste LDPE into liquid fuel. As LDPE is the long chain hydrocarbon polymer, it has to be broken into small chains hydrocarbons which have been done by catalytic cracking of the LDPE. Coal fly ash is used as a catalyst for thermal cracking of the LDPE. The 54 % yield of process was observed during experimentation. We modified readymade mild still pressure cooker of 9 litre capacity as a reactor for this experiment. The glass condenser is used for condensing the generated vapours during process. We found 270 ml of fuel from 500 grams of waste LDPE at reaction temperature of 3000C. The source of waste LDPE is the milk pouches treated as the waste after utilisation of the milk. The fuel analysis shows that the specific gravity at 280C is 0.7466, density at 280C is 0.7228 g/cm3, viscosity is 1.38 cP, volatile matter is 100 %, flash point is 4 0C, pour point is <-5 0C, acid value is 0.058, total ash is 0.00 %, moisture content is 0.10 %, carbon residue is 0.15 %, sulphur content is 206 ppm and gross calorific value is 9970 kcal/kg.
{"title":"Polyfuel - A Catalytic Thermal Cracking of Waste LDPE to Produce Liquid Fuel","authors":"Y. Chauhan, S. Bhagat","doi":"10.32861/ajc.312.109-117","DOIUrl":"https://doi.org/10.32861/ajc.312.109-117","url":null,"abstract":"This work is the diminutive attempt towards the plastic waste recycling conducted at Department of Plastic Engineering, Government Polytechnic, Miraj. The term ‘Polyfuel’ means the liquid fuel produced from waste plastics. We have performed the experiment for conversion of waste LDPE into liquid fuel. As LDPE is the long chain hydrocarbon polymer, it has to be broken into small chains hydrocarbons which have been done by catalytic cracking of the LDPE. Coal fly ash is used as a catalyst for thermal cracking of the LDPE. The 54 % yield of process was observed during experimentation. We modified readymade mild still pressure cooker of 9 litre capacity as a reactor for this experiment. The glass condenser is used for condensing the generated vapours during process. We found 270 ml of fuel from 500 grams of waste LDPE at reaction temperature of 3000C. The source of waste LDPE is the milk pouches treated as the waste after utilisation of the milk. The fuel analysis shows that the specific gravity at 280C is 0.7466, density at 280C is 0.7228 g/cm3, viscosity is 1.38 cP, volatile matter is 100 %, flash point is 4 0C, pour point is <-5 0C, acid value is 0.058, total ash is 0.00 %, moisture content is 0.10 %, carbon residue is 0.15 %, sulphur content is 206 ppm and gross calorific value is 9970 kcal/kg.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90674670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-25DOI: 10.32861/ajc.511.118.123
Gang Bian, X. Pang, Youfang Ke, Xinyang Weng, Yanyi Li
In order to establish a research-based experimental platform for students to fully mobilize initiative and learning creativity, it is necessary to establish design and exploratory experiments to highlight independent exploration and innovation. Through experimental device improvement and material screening, the three parts of fluidization curve measurement, fixed bed drying and fluidized bed drying of spherical molecular sieve are integrated into an organic entirety. Especially, the traditional basic experiment is promoted to a design and research experimental project. Results show that students experimental design ability and comprehensive quality have been improved, and it also stimulated their learning interest, cultivated the creative ability.
{"title":"Construction and Application of Fixed Bed, Fluidized Bed and Fluidized Drying Comprehensive Experiment","authors":"Gang Bian, X. Pang, Youfang Ke, Xinyang Weng, Yanyi Li","doi":"10.32861/ajc.511.118.123","DOIUrl":"https://doi.org/10.32861/ajc.511.118.123","url":null,"abstract":"In order to establish a research-based experimental platform for students to fully mobilize initiative and learning creativity, it is necessary to establish design and exploratory experiments to highlight independent exploration and innovation. Through experimental device improvement and material screening, the three parts of fluidization curve measurement, fixed bed drying and fluidized bed drying of spherical molecular sieve are integrated into an organic entirety. Especially, the traditional basic experiment is promoted to a design and research experimental project. Results show that students experimental design ability and comprehensive quality have been improved, and it also stimulated their learning interest, cultivated the creative ability.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81744182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-11-15DOI: 10.32861/ajc.311.101.108
M. J., M. I. Z., W. H. Z., N. R
Biogas is anaerobic degradation product formed from aqueous slurry of organic waste in a digester. It can be produced from cattle dung, (cd)chicken droppings, decaying leaves, kitchen waste foods, (kwf), sewage sludge, slaughter house, goat, pig or sheep manure, Aqueous slurry of 200 g/L of mixed or single substrate of cattle dung or/and kitchen waste evolved up to 400mL of biogas at ambient temperatures. The rate of gas evolution reached 5 mL/day on the 15th day using 25 % cd mixed slurry. The overall rates of degradation attained in the mixtures were 1.42 + 0.26 mL/g for cd; 1.58+0.33 mL/g for kwf; 1.78+ 0.38 mL/g for 75 % cd mixed substrate; 1.78+ 0.29 mL/g for 50 % cd mixed substrate; 1.92+ 0.21 mL/g for 25 % cd mixed substrate slurries in the 200 g/L load. The comparative rate of biogas formation ranged from1.25 to 1.35 which was in agreement with the range published in literature of 0.8 to 5.5. Biogas can be synthesized efficiently at ambient temperature in Kampala as was done at mesophilic temperatures elsewhere. However, it may be necessary to attempt producing biogas at different pH and temperatures as well as using other substrates and inoculums.
{"title":"Assessing Performance of Cattle Dung and Waste Cooked Foods in Producing Biogas as Single Substrate and Mixed Substrates in Kampala Uganda","authors":"M. J., M. I. Z., W. H. Z., N. R","doi":"10.32861/ajc.311.101.108","DOIUrl":"https://doi.org/10.32861/ajc.311.101.108","url":null,"abstract":"Biogas is anaerobic degradation product formed from aqueous slurry of organic waste in a digester. It can be produced from cattle dung, (cd)chicken droppings, decaying leaves, kitchen waste foods, (kwf), sewage sludge, slaughter house, goat, pig or sheep manure, Aqueous slurry of 200 g/L of mixed or single substrate of cattle dung or/and kitchen waste evolved up to 400mL of biogas at ambient temperatures. The rate of gas evolution reached 5 mL/day on the 15th day using 25 % cd mixed slurry. The overall rates of degradation attained in the mixtures were 1.42 + 0.26 mL/g for cd; 1.58+0.33 mL/g for kwf; 1.78+ 0.38 mL/g for 75 % cd mixed substrate; 1.78+ 0.29 mL/g for 50 % cd mixed substrate; 1.92+ 0.21 mL/g for 25 % cd mixed substrate slurries in the 200 g/L load. The comparative rate of biogas formation ranged from1.25 to 1.35 which was in agreement with the range published in literature of 0.8 to 5.5. Biogas can be synthesized efficiently at ambient temperature in Kampala as was done at mesophilic temperatures elsewhere. However, it may be necessary to attempt producing biogas at different pH and temperatures as well as using other substrates and inoculums.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81340876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acetophenone oximes 1 – 5 along with their terphthaloyl oxime esters 6 – 10 have been synthesized in moderate to good yields. Only one oxime was formed in as E/Z two isomers in a ratio of (8:1). These resulting oxime derivatives were involved in an antifungal screening against the Aspergillus niger at concentration of 30 ppm. Two commercially available antifungal agents, clorotimazole and daktarin, were employed as references at the same concentration, 30 ppm. The antifungal results for the oxime derivatives 1 – 10 showed inhibitory levels ranging from 38% to 100%, whereas the antifungal potentials for the two references were found to be ~ 63% and 68% for clorotimazole and daktarin respectively.
{"title":"Synthesis and Antifungal Study of Some Acetophenone Oximes and Their Terphthaloyl Oxime Esters","authors":"Ramadan Ali Bawa, Mona Mohammed Friwan","doi":"10.32861/ajc.510.96.101","DOIUrl":"https://doi.org/10.32861/ajc.510.96.101","url":null,"abstract":"Acetophenone oximes 1 – 5 along with their terphthaloyl oxime esters 6 – 10 have been synthesized in moderate to good yields. Only one oxime was formed in as E/Z two isomers in a ratio of (8:1). These resulting oxime derivatives were involved in an antifungal screening against the Aspergillus niger at concentration of 30 ppm. Two commercially available antifungal agents, clorotimazole and daktarin, were employed as references at the same concentration, 30 ppm. The antifungal results for the oxime derivatives 1 – 10 showed inhibitory levels ranging from 38% to 100%, whereas the antifungal potentials for the two references were found to be ~ 63% and 68% for clorotimazole and daktarin respectively.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"133 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76401151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nanosized zirconium phosphate and nano fibrous cerium phosphate , Zr(HPO4)2.H2O(nZrP) , Ce(HPO4)2.2.9H2O (nCePf), respectively, were prepared and characterized. Mixing slurry aqueous solution of (nZrP and nCeP f ) in 25:75 wt/wt% mixing ratios) , respectively, lead to formation of novel zirconium phosphatefibrous cerium phosphate nanocomposite membrane, [Zr(HPO4)2]0.25[Ce(HPO4)2]0.75.3.87H2O(nZrP-nCePf), was characterized. Zirconium phosphate-fibrous cerium phosphate/ polybenzimidazole-/polybenzimidazolee-co-polyaniline/polybenzimidazole-co-polypyrrole-/polybenzimidazole-co-polyindole nanocomposite membranes were prepared via in-situ chemical oxidation polymerization of the benzimidazole, and its co-monomers in alcohol, that was promoted by the reduction of Ce(iv) ions present in the inorganic matrix of (nZrP-nCePf ) nanocomposite membrane. A possible explanation is nCePf , present on the surface of composite membrane, is attacked by benzimidazole and its co-monomers , converted to cerium(III) orthophosphate(CePO4). The resultant materials were characterized by elemental (C,H,N) analysis , FT-IR, and scanning electron microscopy(SEM) .. SEM images of the resulting nanocomposites reveal a uniform distribution of the polybenzimidazole and its co-polymers on the inorganic matrix. From elemental (C,H,N) analysis the amount of organic material (PBI) present in (nZrP-nCePf)/PBI composite found to be = 5.7% in wt.. T.he amount of organic materials present in copolymers found to be for (nZrP-nCePf)/PBI-co-PANI (PBI = 9.33%, PANI= 13.32% in wt)., for (nZrP-nCePf) /PBI -co-PPy (PBI = 12.85%, PPy = 7.1% in wt) , and for (nZrPnCePf) /PBI-co-PIn ( PBI = 16.47% , PIn = 8.81% in wt).
{"title":"Zirconium Phosphate/Fibrous Cerium Phosphate Nanocomposite Membrane Self Supported Benzimidazole, Its Co-Aniline, Co-Pyrrole and Co-Indole Polymerization Agent","authors":"S. Shakshooki, F. A. Elakari, A. M. Shaabani","doi":"10.32861/ajc.10.88.100","DOIUrl":"https://doi.org/10.32861/ajc.10.88.100","url":null,"abstract":"Nanosized zirconium phosphate and nano fibrous cerium phosphate , Zr(HPO4)2.H2O(nZrP) , Ce(HPO4)2.2.9H2O (nCePf), respectively, were prepared and characterized. Mixing slurry aqueous solution of (nZrP and nCeP f ) in 25:75 wt/wt% mixing ratios) , respectively, lead to formation of novel zirconium phosphatefibrous cerium phosphate nanocomposite membrane, [Zr(HPO4)2]0.25[Ce(HPO4)2]0.75.3.87H2O(nZrP-nCePf), was characterized. Zirconium phosphate-fibrous cerium phosphate/ polybenzimidazole-/polybenzimidazolee-co-polyaniline/polybenzimidazole-co-polypyrrole-/polybenzimidazole-co-polyindole nanocomposite membranes were prepared via in-situ chemical oxidation polymerization of the benzimidazole, and its co-monomers in alcohol, that was promoted by the reduction of Ce(iv) ions present in the inorganic matrix of (nZrP-nCePf ) nanocomposite membrane. A possible explanation is nCePf , present on the surface of composite membrane, is attacked by benzimidazole and its co-monomers , converted to cerium(III) orthophosphate(CePO4). The resultant materials were characterized by elemental (C,H,N) analysis , FT-IR, and scanning electron microscopy(SEM) .. SEM images of the resulting nanocomposites reveal a uniform distribution of the polybenzimidazole and its co-polymers on the inorganic matrix. From elemental (C,H,N) analysis the amount of organic material (PBI) present in (nZrP-nCePf)/PBI composite found to be = 5.7% in wt.. T.he amount of organic materials present in copolymers found to be for (nZrP-nCePf)/PBI-co-PANI (PBI = 9.33%, PANI= 13.32% in wt)., for (nZrP-nCePf) /PBI -co-PPy (PBI = 12.85%, PPy = 7.1% in wt) , and for (nZrPnCePf) /PBI-co-PIn ( PBI = 16.47% , PIn = 8.81% in wt).","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88904312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Various complexes of DHA with transition-metal cations are known for their antifungal properties. Here, four novel Zn and Cd complexes were prepared via the substitution of water by pyridine andg-picoline using Zn(DHA)2(H2O)2 (2) and Cd(DHA)2(H2O)2 (3) as starting materials. The products were characterized by IR, UV, elemental analysis, TGA and NMR techniques, including correlation times and intermolecular distance measurements using the NULL pulse sequence. The experimental data were compared to the molecular modeling results using DFT and the semiempirical method PM3, confirming that the pentacoordinated Zn complexes have bipyramidal geometry while the Cd complexes have the expected octahedral geometry. These results show that substitution of Zn by Cd leads to an important modification of the coordination structure, especially when strong ligands are involved.
{"title":"Synthesis and Spectroscopic Determination of the Coordination Differences of Cadmium and Zinc Complexes of Dehydroacetic Acid with Pyridine and g-Picoline","authors":"E. Carvalho, R. R. Riente, J. Villar","doi":"10.32861/ajc.49.81.89","DOIUrl":"https://doi.org/10.32861/ajc.49.81.89","url":null,"abstract":"Various complexes of DHA with transition-metal cations are known for their antifungal properties. Here, four novel Zn and Cd complexes were prepared via the substitution of water by pyridine andg-picoline using Zn(DHA)2(H2O)2 (2) and Cd(DHA)2(H2O)2 (3) as starting materials. The products were characterized by IR, UV, elemental analysis, TGA and NMR techniques, including correlation times and intermolecular distance measurements using the NULL pulse sequence. The experimental data were compared to the molecular modeling results using DFT and the semiempirical method PM3, confirming that the pentacoordinated Zn complexes have bipyramidal geometry while the Cd complexes have the expected octahedral geometry. These results show that substitution of Zn by Cd leads to an important modification of the coordination structure, especially when strong ligands are involved.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86466612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Pd-precatalyst was found to exhibit high catalytic activity for C-C bond formation in Suzuki-Miyaura cross-coupling reactions of differentheteroaryl (5-bromo-2-bromoacetyl) thiophene,4- (5-bromothiophen-2-yl)-methyl-1,3-thiazole,isoquinolinium bromide salt) with either aryl or heteroarylboronic acids. All reactions in this study were conducted in water under thermal heating as well as microwave irradiation conditions. The antimicrobial activities of synthesized compounds were evaluated against eight different strains of microorganisms (four fungal strains, two Gram-positive bacteria and two Gram-negative bacteria) using a cup plate diffusion method. The results showed that, most of the 20 tested compounds exhibited varying degrees of antimicrobial activities. However, 6 compounds recorded high antifungal activity (≤ 20 mm zone of inhibition), 3 were antibacterial (against Gram-positive) and 4 showed high broad-spectrum antibacterial efficacy (against Gram-positive and Gram-negative). These bioactive compounds are recommended for further pharmacological and toxicological investigations for possible formulation as wide spectrum antibacterial and antifungal agents. take longer time (30-40 min). The 20 cross- couple products were screened for their antimicrobial potential. The results reproduced 6 new antifungal, 3 new antibacterial (against Gram-positive) and 4 wide spectrum antibacterial agents (against gram-positive and gram-negative). These interesting findings could be the base for further future investigations in order to synthesize novel antimicrobial drugs.
{"title":"Antimicrobial Evaluation of New Synthesized Aza Heterocycles","authors":"M. B. Elamin, S. M. Ali, E. Abdallah","doi":"10.32861/ajc.39.78.87","DOIUrl":"https://doi.org/10.32861/ajc.39.78.87","url":null,"abstract":"The Pd-precatalyst was found to exhibit high catalytic activity for C-C bond formation in Suzuki-Miyaura cross-coupling reactions of differentheteroaryl (5-bromo-2-bromoacetyl) thiophene,4- (5-bromothiophen-2-yl)-methyl-1,3-thiazole,isoquinolinium bromide salt) with either aryl or heteroarylboronic acids. All reactions in this study were conducted in water under thermal heating as well as microwave irradiation conditions. The antimicrobial activities of synthesized compounds were evaluated against eight different strains of microorganisms (four fungal strains, two Gram-positive bacteria and two Gram-negative bacteria) using a cup plate diffusion method. The results showed that, most of the 20 tested compounds exhibited varying degrees of antimicrobial activities. However, 6 compounds recorded high antifungal activity (≤ 20 mm zone of inhibition), 3 were antibacterial (against Gram-positive) and 4 showed high broad-spectrum antibacterial efficacy (against Gram-positive and Gram-negative). These bioactive compounds are recommended for further pharmacological and toxicological investigations for possible formulation as wide spectrum antibacterial and antifungal agents. take longer time (30-40 min). The 20 cross- couple products were screened for their antimicrobial potential. The results reproduced 6 new antifungal, 3 new antibacterial (against Gram-positive) and 4 wide spectrum antibacterial agents (against gram-positive and gram-negative). These interesting findings could be the base for further future investigations in order to synthesize novel antimicrobial drugs.","PeriodicalId":6965,"journal":{"name":"Academic Journal of Chemistry","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81385108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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