V. Lakshmanakumar, G. Arthi, Jayaraj Rathinam, Venkatesan Harishanbuselvan, D. Sivaraman
{"title":"Molecular docking analysis to validate the efficacy of traditional Siddha polyherbal Formulation Aavarai Bhavanai Chooranam (ABC) against enzyme alpha-glucosidase for Type II Diabetes Mellitus","authors":"V. Lakshmanakumar, G. Arthi, Jayaraj Rathinam, Venkatesan Harishanbuselvan, D. Sivaraman","doi":"10.53388/tmrim202307001","DOIUrl":"https://doi.org/10.53388/tmrim202307001","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In the wave of big data, can traditional medicine for the diagnosis and treatment of skeletal disorders be given a new lease of life?","authors":"Zhu Shao, Shuying Bi","doi":"10.53388/tmrim202307005","DOIUrl":"https://doi.org/10.53388/tmrim202307005","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The increasing prevalence of hypothyroidism, which can cause endocrine dysfunction, abnormal neurological function, and cardiovascular and cerebrovascular injuries, poses serious health problems. Thyroid hormone supplementation constitutes the current main therapeutic method for hypothyroidism, yet it has many limitations and risks and is not suitable for everyone. Therefore, it is necessary to seek alternative and complementary treatment methods. It has been proven in practice that traditional Chinese medicine (TCM) possesses multi-channel comprehensive characteristics for the treatment of hypothyroidism and has more advantages than single thyroid hormone supplementation. Through a comprehensive examination of existing literature about TCM efficacy in addressing hypothyroidism, we have meticulously consolidated the most recent research findings on prescriptions and herbal substances employed in the treatment of this condition. Furthermore, we have explicated their respective functions in the management of hypothyroidism, thereby offering valuable perspectives and recommendations for the prospective utilization of natural remedies in its treatment.
{"title":"Traditional Chinese medicine prescriptions and herbs for the treatment of hypothyroidism: a narrative review","authors":"Jun-Qi Li, Ying Li, Jiahui Niu, Yi-han Huang, Jia-Cheng Zhang, Jing Zhang, Mengyao Tang, Wei Dang","doi":"10.53388/tmrim202307024","DOIUrl":"https://doi.org/10.53388/tmrim202307024","url":null,"abstract":"The increasing prevalence of hypothyroidism, which can cause endocrine dysfunction, abnormal neurological function, and cardiovascular and cerebrovascular injuries, poses serious health problems. Thyroid hormone supplementation constitutes the current main therapeutic method for hypothyroidism, yet it has many limitations and risks and is not suitable for everyone. Therefore, it is necessary to seek alternative and complementary treatment methods. It has been proven in practice that traditional Chinese medicine (TCM) possesses multi-channel comprehensive characteristics for the treatment of hypothyroidism and has more advantages than single thyroid hormone supplementation. Through a comprehensive examination of existing literature about TCM efficacy in addressing hypothyroidism, we have meticulously consolidated the most recent research findings on prescriptions and herbal substances employed in the treatment of this condition. Furthermore, we have explicated their respective functions in the management of hypothyroidism, thereby offering valuable perspectives and recommendations for the prospective utilization of natural remedies in its treatment.","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70830297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Material basis and mechanism research progress of Curcumae Rhizoma-Sparganii Rhizoma herb pair ameliorates liver fibrosis","authors":"Zhouhui Yao, Zi-Yan Chen, Pingping Wang, Min Hao","doi":"10.53388/tmrim202307003","DOIUrl":"https://doi.org/10.53388/tmrim202307003","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"236 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effects of Buyang Huanwu decoction combined with Western medicine in diabetic foot treatment: a systematic review and meta-analysis","authors":"","doi":"10.53388/tmrim202307010","DOIUrl":"https://doi.org/10.53388/tmrim202307010","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Traditional Chinese medicine: Eastern natural remedy for management of lipid metabolic disorders","authors":"Wei Peng","doi":"10.53388/tmrim202307015","DOIUrl":"https://doi.org/10.53388/tmrim202307015","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70830081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dry eye disease (DED), a chronic multifactorial illness of the ocular surface with itching, burning, irritation, eye fatigue and ocular inflammation, may result in potential damage, such as cornea and conjunctiva, and even decreased vision. With the global prevalence of DED on the rise, it is crucial to find treatment options with minimal side effects. Natural plant products have shown promise in alleviating DED symptoms and may serve as a potential approach for its treatment. However, their application as instilled drugs is limited by solubility, stability and biological barriers. This review summarizes recent studies (published in the last 5 years) on natural plant products and their derivatives for the treatment of DED, focusing on efficacy, mechanism, drug delivery systems. Meanwhile, their shortcomings are also discussed. By exploring these aspects, we find polyphenol, flavonoid and others natural plant products can effectively improve or treat DED by different mechanisms, and suitable delivery system and structural modification can enhance their therapeutic effect, suggesting they are likely to become candidates for the treatment of DED.
{"title":"Recent advance in natural plant products for treatment of dry eye disease","authors":"Yi Wang, Xiushan Chen","doi":"10.53388/tmrim202307023","DOIUrl":"https://doi.org/10.53388/tmrim202307023","url":null,"abstract":"Dry eye disease (DED), a chronic multifactorial illness of the ocular surface with itching, burning, irritation, eye fatigue and ocular inflammation, may result in potential damage, such as cornea and conjunctiva, and even decreased vision. With the global prevalence of DED on the rise, it is crucial to find treatment options with minimal side effects. Natural plant products have shown promise in alleviating DED symptoms and may serve as a potential approach for its treatment. However, their application as instilled drugs is limited by solubility, stability and biological barriers. This review summarizes recent studies (published in the last 5 years) on natural plant products and their derivatives for the treatment of DED, focusing on efficacy, mechanism, drug delivery systems. Meanwhile, their shortcomings are also discussed. By exploring these aspects, we find polyphenol, flavonoid and others natural plant products can effectively improve or treat DED by different mechanisms, and suitable delivery system and structural modification can enhance their therapeutic effect, suggesting they are likely to become candidates for the treatment of DED.","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70830232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Kahwa, Clement Olusoji Ajayi, R. Yadav, Nagendra Singh Chauhan, K. Shah, Abdelgadir Alamin Abdelgadir, Efrata Ashuro Shegena, Salome Daniel, Timothy Omara, J. Asiimwe, Hilda Ikiriza, S. Iqbal, C. Tolo, A. Weisheit, P. Ogwang
{"title":"Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda","authors":"I. Kahwa, Clement Olusoji Ajayi, R. Yadav, Nagendra Singh Chauhan, K. Shah, Abdelgadir Alamin Abdelgadir, Efrata Ashuro Shegena, Salome Daniel, Timothy Omara, J. Asiimwe, Hilda Ikiriza, S. Iqbal, C. Tolo, A. Weisheit, P. Ogwang","doi":"10.53388/tmrim202307004","DOIUrl":"https://doi.org/10.53388/tmrim202307004","url":null,"abstract":"","PeriodicalId":70680,"journal":{"name":"TMR整合医学","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70829582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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