E. Yuanita, Baiq Khaeratul Jannah, M. Ulfa, Sudirman, Baiq Nila Sari Ningsih, N. K. T. Dharmayani
Prenylated 1,3-dihydroxyxanthone has been successfully synthesized using Prenyl bromide and KOH. Characterization of the synthesized compound using Infra Red (IR) and Nuclear Magnetic Resonance (1H-NMR) showed that monosubstituted c-prenylation was occurred at carbon number 2 to form 1,3-dihydroxy-2-prenylxanthone. The synthesis result was a yellow-brown paste with a yield of 43.09%. This prenylated 1,3-dihydroxyxanthone had moderate antibacterial activity against Escherichia coli with an inhibition zone > 5 mm at a concentration of 15%.
{"title":"C-prenylation of 1,3 dihydroxyxanthone: synthesis, characterization and antibacterial activity","authors":"E. Yuanita, Baiq Khaeratul Jannah, M. Ulfa, Sudirman, Baiq Nila Sari Ningsih, N. K. T. Dharmayani","doi":"10.29303/aca.v6i1.149","DOIUrl":"https://doi.org/10.29303/aca.v6i1.149","url":null,"abstract":"Prenylated 1,3-dihydroxyxanthone has been successfully synthesized using Prenyl bromide and KOH. Characterization of the synthesized compound using Infra Red (IR) and Nuclear Magnetic Resonance (1H-NMR) showed that monosubstituted c-prenylation was occurred at carbon number 2 to form 1,3-dihydroxy-2-prenylxanthone. The synthesis result was a yellow-brown paste with a yield of 43.09%. This prenylated 1,3-dihydroxyxanthone had moderate antibacterial activity against Escherichia coli with an inhibition zone > 5 mm at a concentration of 15%.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88302601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This experimental research aims to characterize the complex compound M-curcumin (M=Cu, Co, Ag) based on turmeric (Curcuma longa Linn) rhizome as a candidate for photosensitizer in solar cells. The basic material used for manufacturing the M-curcumin complex compound in this study was curcumin from turmeric rhizome extract added to Cu2+, Co2+, and Ag+ metal ions. The results of the synthesis of the M-curcumin complex were characterized by FTIR and Uv-Vis spectrophotometers. The FTIR spectrophotometer test showed a curcumin compound in the viscous curcumin extract, characterized by an absorption wave number corresponding to the curcumin compound. In the M-curcumin complex, the bond between the metal and the ligand only appears in the Co-curcumin complex at the absorption number of 498.77 cm -1. The results of the UV-Vis spectrophotometer test showed that the maximum wavelength absorption in curcumin extract was 430 nm (abs = 0.688), Cu-Curcumin complex lmax 300 nm (abs = 2.573), Co-curcumin complex lmax 425 nm (abs = 1.067), and complex Ag-Curcumin lmax 430 nm (abs = 1.36). The UV-Vis and FTIR characterization showed that the Co-curcumin complex has good potential compared to the organic compounds (curcumin) and can be used as an alternative photosensitizer in solar cells
{"title":"Characterization of M-curcumin complexes (M= Cu, Co, Ag) in turmeric rhizome as sensitizer candidates in dye-sensitized solar cell (DSSC)","authors":"Ainun Jariah, S. Hadisaputra, A. Purwoko","doi":"10.29303/aca.v6i1.152","DOIUrl":"https://doi.org/10.29303/aca.v6i1.152","url":null,"abstract":"This experimental research aims to characterize the complex compound M-curcumin (M=Cu, Co, Ag) based on turmeric (Curcuma longa Linn) rhizome as a candidate for photosensitizer in solar cells. The basic material used for manufacturing the M-curcumin complex compound in this study was curcumin from turmeric rhizome extract added to Cu2+, Co2+, and Ag+ metal ions. The results of the synthesis of the M-curcumin complex were characterized by FTIR and Uv-Vis spectrophotometers. The FTIR spectrophotometer test showed a curcumin compound in the viscous curcumin extract, characterized by an absorption wave number corresponding to the curcumin compound. In the M-curcumin complex, the bond between the metal and the ligand only appears in the Co-curcumin complex at the absorption number of 498.77 cm -1. The results of the UV-Vis spectrophotometer test showed that the maximum wavelength absorption in curcumin extract was 430 nm (abs = 0.688), Cu-Curcumin complex lmax 300 nm (abs = 2.573), Co-curcumin complex lmax 425 nm (abs = 1.067), and complex Ag-Curcumin lmax 430 nm (abs = 1.36). The UV-Vis and FTIR characterization showed that the Co-curcumin complex has good potential compared to the organic compounds (curcumin) and can be used as an alternative photosensitizer in solar cells","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82482111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annisa Rahmadhani, Hasmalina Nasution, P. Prasetya, Novialis Dayumita, Sri Hilma Siregar
Wastewater originating from household, industrial, and public places that contains materials can endanger human life and living things and disrupt environmental sustainability. Various methods have recycled domestic wastewater. One is through the photodegradation process utilizing ultraviolet light in the photocatalytic process. Inorganic materials are semiconductors with photocatalyst activity that can absorb photons and simultaneously carry out material interface transformation reactions. The research aimed to determine the effect of adding Fe metal dopants on TiO2 photocatalyst activity in simulated methylene blue and domestic waste treatment. The precursor used was TiO2 P25 Degussa Anatase. Fe dopant was added using the hydrothermal method with variations of 2%, 4%, and 6%. The XRD characterization results show that TiO2 has a high degree of crystallinity, so the overall process of electron diffusion and electron transfer in SSPT is higher to increase its efficiency. SEM-EDX characterization results show that TiO2-Fe particles are scattered in a spherical shape with a size of less than (<)100 nm and tend to agglomerate. Test results of simulated methylene blue (MB) waste with a UV-Vis spectrophotometer at variations in mass, concentration, pH, and time showed that the addition of doping could increase photocatalytic activity and optimum conditions at 6% (F6) were used in the analysis of parameters pH, COD and TSS of domestic wastewater. The pH value increased from 5 to 6, % COD degradation was 59.17%, and TSS was 23.07%. This research showed that TiO2-Fe was effective enough for domestic wastewater treatment.
{"title":"Synthesis and characterization of TiO2-Fe for photocatalytic applications of domestic waste","authors":"Annisa Rahmadhani, Hasmalina Nasution, P. Prasetya, Novialis Dayumita, Sri Hilma Siregar","doi":"10.29303/aca.v6i1.140","DOIUrl":"https://doi.org/10.29303/aca.v6i1.140","url":null,"abstract":"Wastewater originating from household, industrial, and public places that contains materials can endanger human life and living things and disrupt environmental sustainability. Various methods have recycled domestic wastewater. One is through the photodegradation process utilizing ultraviolet light in the photocatalytic process. Inorganic materials are semiconductors with photocatalyst activity that can absorb photons and simultaneously carry out material interface transformation reactions. The research aimed to determine the effect of adding Fe metal dopants on TiO2 photocatalyst activity in simulated methylene blue and domestic waste treatment. The precursor used was TiO2 P25 Degussa Anatase. Fe dopant was added using the hydrothermal method with variations of 2%, 4%, and 6%. The XRD characterization results show that TiO2 has a high degree of crystallinity, so the overall process of electron diffusion and electron transfer in SSPT is higher to increase its efficiency. SEM-EDX characterization results show that TiO2-Fe particles are scattered in a spherical shape with a size of less than (<)100 nm and tend to agglomerate. Test results of simulated methylene blue (MB) waste with a UV-Vis spectrophotometer at variations in mass, concentration, pH, and time showed that the addition of doping could increase photocatalytic activity and optimum conditions at 6% (F6) were used in the analysis of parameters pH, COD and TSS of domestic wastewater. The pH value increased from 5 to 6, % COD degradation was 59.17%, and TSS was 23.07%. This research showed that TiO2-Fe was effective enough for domestic wastewater treatment.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74321882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flavone compounds present as secondary metabolites in many plants have beneficial phytochemical activity. Isolation of flavones from various parts of plants has been widely carried out, but the synthesis pathway is another way to obtain higher yields. This research aimed to synthesize flavone compounds from vanillin and 2-hydroxyacetophenone through chalcone intermediates to produce a 74% yield using an iodide catalyst. This new flavone compound has been used as a chemosensor to detect anions
{"title":"Synthesis novel flavone from vanillin","authors":"R. Rahmawati, Baiq Fara Dwirani Sofia","doi":"10.29303/aca.v6i1.127","DOIUrl":"https://doi.org/10.29303/aca.v6i1.127","url":null,"abstract":"Flavone compounds present as secondary metabolites in many plants have beneficial phytochemical activity. Isolation of flavones from various parts of plants has been widely carried out, but the synthesis pathway is another way to obtain higher yields. This research aimed to synthesize flavone compounds from vanillin and 2-hydroxyacetophenone through chalcone intermediates to produce a 74% yield using an iodide catalyst. This new flavone compound has been used as a chemosensor to detect anions","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86371682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anisa Noorlela, A. Nandiyanto, R. Ragadhita, Teguh Kurniawan
This study aims to design a continuous stirred tank reactor (CSTR) type reactor to produce zinc oxide (ZnO) nanoparticles. Mass balance calculations were carried out in this study as a benchmark to determine whether the reactor was working properly by knowing the flow of incoming raw materials and the products produced by the reactor. Furthermore, the reactor's design and the stirrer used in the reactor are calculated manually using Microsoft Excel. Based on the calculation results of the reactor design, the reactor volume is 8224.359 liters, with a vessel diameter of 73.298 in, a cylinder height of 166.090 in, and a cylinder thickness of 73.444 in. The top cover of the reactor measures 12.387 inches with a thickness of 0.072 inches, while the bottom cover measures 21.185 inches with a thickness of 0.083 inches, so the overall height of the reactor is 37.552 in. The reactor is equipped with one stirrer with an impeller diameter of 36.722 in, impeller height from the bottom of the tank is 24.433 in, impeller width is 7.344 in, and impeller length is 9.180 in. Turbulent stirring flow conditions with a standard motor power for the stirrer is 6.849 HP. This design will be a reference for building more economical, efficient, and highly demanding reactors.
{"title":"Design of reactor for the production of zinc oxide nanoparticles","authors":"Anisa Noorlela, A. Nandiyanto, R. Ragadhita, Teguh Kurniawan","doi":"10.29303/aca.v6i1.146","DOIUrl":"https://doi.org/10.29303/aca.v6i1.146","url":null,"abstract":"This study aims to design a continuous stirred tank reactor (CSTR) type reactor to produce zinc oxide (ZnO) nanoparticles. Mass balance calculations were carried out in this study as a benchmark to determine whether the reactor was working properly by knowing the flow of incoming raw materials and the products produced by the reactor. Furthermore, the reactor's design and the stirrer used in the reactor are calculated manually using Microsoft Excel. Based on the calculation results of the reactor design, the reactor volume is 8224.359 liters, with a vessel diameter of 73.298 in, a cylinder height of 166.090 in, and a cylinder thickness of 73.444 in. The top cover of the reactor measures 12.387 inches with a thickness of 0.072 inches, while the bottom cover measures 21.185 inches with a thickness of 0.083 inches, so the overall height of the reactor is 37.552 in. The reactor is equipped with one stirrer with an impeller diameter of 36.722 in, impeller height from the bottom of the tank is 24.433 in, impeller width is 7.344 in, and impeller length is 9.180 in. Turbulent stirring flow conditions with a standard motor power for the stirrer is 6.849 HP. This design will be a reference for building more economical, efficient, and highly demanding reactors.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79764530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sri Hilma Siregar, Syafri Rahmadini, Nasution Hasmalina, Ramadhanti Aulia Rizki, Kafri Eri
This study aims to see the potential of bamboo as a new raw material for the Indonesian pulp industry, specifically for the manufacture of pulp products, because in Indonesia, the import value for dissolving is still high, and the raw materials used still use wood plants. This study consists of three stages: the pre-hydrolysis stage using water, the cooking stage with the kraft pulping method, and bleaching using the elemental chlorine-free (ECF) method. Bamboo flakes that run into the pre-hydrolysis process decreased the Kappa Number value of pulp produced, which ranges from 4.63% - 14.52% compared to bamboo flakes that do not run into the pre-hydrolysis process. The brightness increase to 0.844% - 2.96% compared to bamboo flakes that do not run into the process of pre-hydrolysis. For pulp products, the value of Alpha Cellulose obtained is around 89.18% - 90.32%.
{"title":"Pulp synthesis using bamboo raw materials through unbleached and bleached processes","authors":"Sri Hilma Siregar, Syafri Rahmadini, Nasution Hasmalina, Ramadhanti Aulia Rizki, Kafri Eri","doi":"10.29303/aca.v6i1.135","DOIUrl":"https://doi.org/10.29303/aca.v6i1.135","url":null,"abstract":"This study aims to see the potential of bamboo as a new raw material for the Indonesian pulp industry, specifically for the manufacture of pulp products, because in Indonesia, the import value for dissolving is still high, and the raw materials used still use wood plants. This study consists of three stages: the pre-hydrolysis stage using water, the cooking stage with the kraft pulping method, and bleaching using the elemental chlorine-free (ECF) method. Bamboo flakes that run into the pre-hydrolysis process decreased the Kappa Number value of pulp produced, which ranges from 4.63% - 14.52% compared to bamboo flakes that do not run into the pre-hydrolysis process. The brightness increase to 0.844% - 2.96% compared to bamboo flakes that do not run into the process of pre-hydrolysis. For pulp products, the value of Alpha Cellulose obtained is around 89.18% - 90.32%.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83320475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meisy A. Massie, I. D. Anom, Djefry Tani, Febrian Solikhin
Plastik merupakan produk yang banyak digunakan ditengah masyarakat yang apabila selesai digunakan akan menjadi limbah, maka dari itu diperlukan pengetahuan tentang komposis dari plastik sehingga kita mendapatkan cara untuk mengolahnya menjadi bahan yang berguna. Telah dilakukan penelitian karakterisasi asap cair hasil pirolisis sampah plastik kemasan minyak goreng jenis PET dan OTHER sebagai bahan bakar altertatif. Asap cair dari sampah plastik jenis PET dan OTHER dibuat dengan metode pirolisis pada suhun tinggi. Salah satu bentuk pengolahan sampah plastik untuk menghasilkan energi adalah mengolah sampah plastik menjadi bahan bakar cair. Pirolisis adalah salah satu metode yang dapat digunakan untuk mengubah sampah plastik menjadi bahan bakar cair dan dapat diproses lebih lanjut menjadi bahan bakar minyak yang sama dengan bahan bakar bensin. Keuntungan menerapkan metode pirolisis antara lain memiliki rasio konversi yang tinggi dan produknya mempunyai kandungan energi yang tinggi pula. Pada Pirolisis yang dilakukan diperoleh pirolisat sampah plastik kemasan minyak goreng jenis PET menghasilkan 77,70% asap cair dan pirolisis sampah plastik kemasan minyak goreng jenis OTHER menghasilkan asap cair kurang lebih 71,65%. Sifat-sifat fisika asap cair hasil pirolisis dari sampah plastik kemasan minyak goreng jenis PET dan jenis ORTHER belum dapat digunakan secara langsung sebagai bahan bakar minyak karena sebagian dari sifat-sifat fisika tersebut belum memenuhi standar mutu bahan bakar berdasarkan SNI. Identifikasi dengan GC-MS bahwa asap cair dari sampah plastik jenis PET terdiri dari 50 senyawa kimia dan asap cair dari sampah plastik jenis OTHER terdiri dari 49 senyawa kimia. Asap cair dari hasil pirolisis sampah plastik jenis PET dan OTHER keduanya tersusun dari turunan senyawa kimia golongan alkana, alkena, sikloalkana, sikloalkena dan alkohol.
{"title":"Karakterisasi Asap Cair Hasil Pirolisis Sampah Plastik Kemasan Minyak Goreng Jenis PET dan Other Sebagai Bahan Bakar Alternatif","authors":"Meisy A. Massie, I. D. Anom, Djefry Tani, Febrian Solikhin","doi":"10.29303/aca.v6i1.121","DOIUrl":"https://doi.org/10.29303/aca.v6i1.121","url":null,"abstract":"Plastik merupakan produk yang banyak digunakan ditengah masyarakat yang apabila selesai digunakan akan menjadi limbah, maka dari itu diperlukan pengetahuan tentang komposis dari plastik sehingga kita mendapatkan cara untuk mengolahnya menjadi bahan yang berguna. Telah dilakukan penelitian karakterisasi asap cair hasil pirolisis sampah plastik kemasan minyak goreng jenis PET dan OTHER sebagai bahan bakar altertatif. Asap cair dari sampah plastik jenis PET dan OTHER dibuat dengan metode pirolisis pada suhun tinggi. Salah satu bentuk pengolahan sampah plastik untuk menghasilkan energi adalah mengolah sampah plastik menjadi bahan bakar cair. Pirolisis adalah salah satu metode yang dapat digunakan untuk mengubah sampah plastik menjadi bahan bakar cair dan dapat diproses lebih lanjut menjadi bahan bakar minyak yang sama dengan bahan bakar bensin. Keuntungan menerapkan metode pirolisis antara lain memiliki rasio konversi yang tinggi dan produknya mempunyai kandungan energi yang tinggi pula. Pada Pirolisis yang dilakukan diperoleh pirolisat sampah plastik kemasan minyak goreng jenis PET menghasilkan 77,70% asap cair dan pirolisis sampah plastik kemasan minyak goreng jenis OTHER menghasilkan asap cair kurang lebih 71,65%. Sifat-sifat fisika asap cair hasil pirolisis dari sampah plastik kemasan minyak goreng jenis PET dan jenis ORTHER belum dapat digunakan secara langsung sebagai bahan bakar minyak karena sebagian dari sifat-sifat fisika tersebut belum memenuhi standar mutu bahan bakar berdasarkan SNI. Identifikasi dengan GC-MS bahwa asap cair dari sampah plastik jenis PET terdiri dari 50 senyawa kimia dan asap cair dari sampah plastik jenis OTHER terdiri dari 49 senyawa kimia. Asap cair dari hasil pirolisis sampah plastik jenis PET dan OTHER keduanya tersusun dari turunan senyawa kimia golongan alkana, alkena, sikloalkana, sikloalkena dan alkohol. ","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74604242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study aims to identify the most responsible compound for the antiinflammation activity from Mitragyna speciosa leaves. Seventeen compounds previously reported to have been isolated from the leave were virtually screened against human 5-lipoxygenase protein and analyzed according to their binding energies. The native ligand used was arachidonic acid, and mitragynine was found to be the strongest binding compound (Pubchem ID: 3034396). In addition, ADMET profiling shows that mitragynine was not violating Lipinski’s rule of five and was not toxic.
{"title":"Identification of Active Compound from Mitragyna speciosa Leave as Antiinflammation Agent: In Silico Study.","authors":"Ihsanul Arief, Erwan Kurnianto","doi":"10.29303/aca.v5i2.139","DOIUrl":"https://doi.org/10.29303/aca.v5i2.139","url":null,"abstract":"The study aims to identify the most responsible compound for the antiinflammation activity from Mitragyna speciosa leaves. Seventeen compounds previously reported to have been isolated from the leave were virtually screened against human 5-lipoxygenase protein and analyzed according to their binding energies. The native ligand used was arachidonic acid, and mitragynine was found to be the strongest binding compound (Pubchem ID: 3034396). In addition, ADMET profiling shows that mitragynine was not violating Lipinski’s rule of five and was not toxic.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76982534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aims to examine the effect of using Augmented Reality-based learning media on students' conceptual understanding of molecular shape material. This research is a quasi-experimental study with a post-test-only design. The class used was class X Mathematics and Natural Sciences in one of the Bengkulu City High Schools, which received molecular shape material, consisting of 1 control class and 1 experimental class. The control class is a class that uses PowerPoint media as usual with 2-dimensional image visualization. In contrast, the experimental class is a class that uses augmented reality-based learning media with 3-dimensional visualization. The instrument used is a post-test instrument referring to conceptual understanding indicators. The results were analyzed using a t-test. The results of the analysis showed that the significance level was 0.002. This result indicates that it is smaller than the significance level, or it can be concluded that there is a significant difference in the average understanding of the concept between the control class and the experimental class.
{"title":"The Effect of Using Augmented Reality-Based Learning Media on Chemistry Students’ Conceptual Understanding on Molecular Shape","authors":"F. Solikhin, Dewi Handayani, Salastri Rohiat","doi":"10.29303/aca.v5i2.128","DOIUrl":"https://doi.org/10.29303/aca.v5i2.128","url":null,"abstract":"This study aims to examine the effect of using Augmented Reality-based learning media on students' conceptual understanding of molecular shape material. This research is a quasi-experimental study with a post-test-only design. The class used was class X Mathematics and Natural Sciences in one of the Bengkulu City High Schools, which received molecular shape material, consisting of 1 control class and 1 experimental class. The control class is a class that uses PowerPoint media as usual with 2-dimensional image visualization. In contrast, the experimental class is a class that uses augmented reality-based learning media with 3-dimensional visualization. The instrument used is a post-test instrument referring to conceptual understanding indicators. The results were analyzed using a t-test. The results of the analysis showed that the significance level was 0.002. This result indicates that it is smaller than the significance level, or it can be concluded that there is a significant difference in the average understanding of the concept between the control class and the experimental class.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75679225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In traditional Melayu Riau medicine, the jackfruit parasite plant, also known as Macrosolen cochinchinensis (Lour.) van Tiegh, has been utilized as a remedy for coughs, a treatment for cancer, a diuretic, and to speed up the recovery process after giving birth. Through in vitro and in silico testing, the purpose of this investigation is to learn more about the bioactive components and antibacterial activity of n-heksan, etilasetat, and etanol obtained from the extracts of the jackfruit parasite plant (Macrosolen cochinchinensis (Lour.) van Tiegh. The disc diffusion method was used for the in vitro testing, and the molecular docking method was used for the in silico testing, both of which were conducted against Staphylococcus aureus ATCC 12600 and Escherichia coli ATCC 25922. Each sample extract was prepared in three different concentrations (10%, 30%, and 50%), while chloramphenicol was used as the positive control. Inhibition zones of the extract against E. coli bacteria were found to be as follows: 6 mm, 8.4 mm, and 10.6 mm for the n-hexane extract; 8.2 mm, 10.7 mm, and 15.6 mm for the ethyl acetate extract; and 6 mm, 7.1 mm, and 14.1 mm for the methanol extract. The results of the test to determine the extract's antibacterial activity were as follows: The following is a list of the zones of inhibition that the extract has against S. aureus bacteria: 6 mm, 7.5 mm, and 13.7 mm in diameter for the extract of n-hexane; 12.8 mm, 14.2 mm, and 19.2 mm in diameter for the extract of ethyl acetate. Test results of 7.2 mm, 9.3 mm, and 15.3 mm were obtained for the methanol extract. In accordance with the findings of the study, the ethyl acetate extract of jackfruit parasite leaves exhibited the highest level of antibacterial activity, as measured by an inhibition zone diameter of 19.2 mm, when tested on S. aureus bacteria. In the meantime, the results of molecular docking of punicalin and rutin, which have been reported to have activity against proteins 6GOS.pdb and 1OJZ.pdb, have potential as antibacterials because they form 5 and 9 hydrogen bonds with important amino acids of the target protein, with cDOCKER values of -57.9239 and -88.3993, respectively. This suggests that punicalin and rutin have the ability to inhibit the growth of bacteria.
{"title":"Evaluation of the Antibacterial Activity of the Jackfruit Parasite Leaf Plant Extract (Macrosolencochinchinensis (Lour.) van Tiegh) with Vitro and In Silico approach","authors":"R. Hilma, Suma Rahmani Harahap, Jufrizal Syahri","doi":"10.29303/aca.v5i2.141","DOIUrl":"https://doi.org/10.29303/aca.v5i2.141","url":null,"abstract":"In traditional Melayu Riau medicine, the jackfruit parasite plant, also known as Macrosolen cochinchinensis (Lour.) van Tiegh, has been utilized as a remedy for coughs, a treatment for cancer, a diuretic, and to speed up the recovery process after giving birth. Through in vitro and in silico testing, the purpose of this investigation is to learn more about the bioactive components and antibacterial activity of n-heksan, etilasetat, and etanol obtained from the extracts of the jackfruit parasite plant (Macrosolen cochinchinensis (Lour.) van Tiegh. The disc diffusion method was used for the in vitro testing, and the molecular docking method was used for the in silico testing, both of which were conducted against Staphylococcus aureus ATCC 12600 and Escherichia coli ATCC 25922. Each sample extract was prepared in three different concentrations (10%, 30%, and 50%), while chloramphenicol was used as the positive control. Inhibition zones of the extract against E. coli bacteria were found to be as follows: 6 mm, 8.4 mm, and 10.6 mm for the n-hexane extract; 8.2 mm, 10.7 mm, and 15.6 mm for the ethyl acetate extract; and 6 mm, 7.1 mm, and 14.1 mm for the methanol extract. The results of the test to determine the extract's antibacterial activity were as follows: The following is a list of the zones of inhibition that the extract has against S. aureus bacteria: 6 mm, 7.5 mm, and 13.7 mm in diameter for the extract of n-hexane; 12.8 mm, 14.2 mm, and 19.2 mm in diameter for the extract of ethyl acetate. Test results of 7.2 mm, 9.3 mm, and 15.3 mm were obtained for the methanol extract. In accordance with the findings of the study, the ethyl acetate extract of jackfruit parasite leaves exhibited the highest level of antibacterial activity, as measured by an inhibition zone diameter of 19.2 mm, when tested on S. aureus bacteria. In the meantime, the results of molecular docking of punicalin and rutin, which have been reported to have activity against proteins 6GOS.pdb and 1OJZ.pdb, have potential as antibacterials because they form 5 and 9 hydrogen bonds with important amino acids of the target protein, with cDOCKER values of -57.9239 and -88.3993, respectively. This suggests that punicalin and rutin have the ability to inhibit the growth of bacteria.","PeriodicalId":7071,"journal":{"name":"Acta Chimica Asiana","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73306208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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