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WITHDRAWN: Revisiting cast removal complications via a prospective controlled study: improved safety with a novel method. 撤回: 通过前瞻性对照研究重新审视石膏拆除并发症:采用新方法提高安全性。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-28 DOI: 10.5152/j.aott.2021.20399
Adnan Sevencan
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引用次数: 0
External fixation in the treatment of displaced supracondylar femoral fracture in children: A retrospective case series. 外固定治疗儿童移位性股骨髁上骨折:回顾性病例系列。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2022.20379
Jin Li, Kailei Chen, Jiewen Ma, X. Guo, Changjie Yue, Saroj Rai, Xin Tang
OBJECTIVEThe aim of this study was to evaluate the clinical and radiological outcomes and complications of external fixation use in the treatment of children with displaced supracondylar femoral fractures..METHODSIn this retrospective study, 14 children (6 boys, 8 girls; mean age = 7.3 years; age range = 3.9 - 10.3 years) who underwent external fixation for the treatment of a displaced supracondylar femoral fracture from 2010 to 2017 were included. Their medical records were reviewed for general information and surgery details. Postoperative information, such as time to radiographic union, time to regain walking ability, Knee Society Scores (KSS) postoperative score, and KSS functional score were collected. Radiographic images were examined for the measurement of leg length discrepancy and valgus deformity.RESULTSThe mean follow up was 34 (range = 24-50) months. The mean time to radiographic union was 12.3 (range = 10-16) weeks, and the mean time to regain walking ability was 11.8 (range = 11-13) weeks. Leg length discrepancies were all less than 0.8 cm, and valgus deformity was all limited in 10°. The mean KSS postoperative score was 97.5 (range = 93-100), and the mean KSS functional score was 97.1 (range = 90-100). None of the patients exhibited functional deficiency. Neither deep infection nor refracture was detected postoperatively.CONCLUSIONExternal fixation seems to be an acceptable alternative modality for treatingdisplaced supracondylar femoral fractures in children, with favorable clinical and radiological outcomes as well as a low complication rate.LEVEL OF EVIDENCELevel IV, Therapeutic Study.
目的评价外固定架治疗儿童移位性股骨髁上骨折的临床和影像学结果及并发症。方法回顾性研究14例儿童(6男,8女;平均年龄7.3岁;年龄范围= 3.9 - 10.3岁),于2010年至2017年接受外固定治疗移位性股骨髁上骨折。检查了他们的医疗记录,以了解一般信息和手术细节。收集术后信息,如放射愈合时间、恢复行走能力时间、膝关节社会评分(KSS)术后评分和KSS功能评分。检查x线图像测量腿长差异和外翻畸形。结果平均随访34个月(范围24 ~ 50个月)。平均放射愈合时间为12.3周(范围= 10-16),平均恢复行走能力时间为11.8周(范围= 11-13)。腿长差异均小于0.8 cm,外翻畸形均控制在10°以内。KSS术后平均评分为97.5分(范围93-100),KSS功能评分为97.1分(范围90-100)。没有患者表现出功能缺陷。术后未见深部感染和再骨折。结论外固定架是治疗儿童移位性股骨髁上骨折的一种可接受的替代方式,具有良好的临床和影像学结果,且并发症发生率低。证据水平:IV级,治疗性研究。
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引用次数: 1
Effect of platelet-rich plasma on bone regenerate consolidation in distraction osteogenesis: An experimental study in rabbits. 富血小板血浆对兔牵张成骨过程中骨再生固结的影响:一项实验研究。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2022.20443
M. Karakayali, Yakup Alpay, B. Sarısözen
OBJECTIVEThe aim of this study was to determine the effect of platelet-rich plasma (PRP) on bone regenerate consolidation in a rabbit model of distraction osteogenesis.METHODSIn this study, 12 male New Zealand rabbits weighing 1600 to 2000 g were used. All the rabbits were randomly divided into two groups (n = 6 per group): PRP group and control group. A two-ring, circular external fixator was applied to the right tibia of each rabbit in both groups. After corticotomy, all the tibiae were distracted at a rate of 0.5 mm/day for 20 days. PRP was injected to the osteotomy sites on the 7th, 14th, and 21st days postoperatively. Mineral density of the new bone tissue formed in the distraction zone was measured using quantitative computed tomography in the 3rd, 4th, and 5th weeks. At the end of the 6th week, the animals were sacrificed, and the specimens were evaluated biomechanically and histologically.RESULTSMicrocomputed tomography assessment showed significant bone mineral density increase from the 3rd to the 6th week (62.3% and 43.7% for the PRP and control groups, respectively). In the PRP group, the measurements on the 3rd, 4th, and 5th weeks were 416 ± 29, 487 ± 9.9, and 675 ± 37.8 HU (Hounsfield units), respectively, whereas in the control group were 313, 374, and 450 HU, respectively. In the comparison of weekly measurements of the two groups, the increase in bone density in the PRP group was higher than that in the control group (P < 0.001). During the mechanical tests, in the PRP group, the mean torsion was 46.50°and the mean torque 0.53 Nm, while in the control group, the mean torsion was 19.33°and the mean torque 0.65 Nm. The mechanical analysis of the groups revealed significant differences in the mean maximum torsion angles (P = 0.024). The histological examination showed that both groups had external and internal periosteal calli. Callus tissue in four rabbits in the PRP group and two rabbits in the control group was remodeled; normal bone formation occurred and distracted bone ends were completely healed.CONCLUSIONThe results of the present study have indicated that PRP injection can enhance bone regenerate consolidation and increase bone mineral density during the healing process of distraction osteogenesis.
本研究的目的是确定富血小板血浆(PRP)在兔牵张成骨模型中对骨再生固结的影响。方法本研究选用12只雄性新西兰兔,体重1600~2000g。将所有家兔随机分为两组(每组n=6):PRP组和对照组。两组兔的右胫骨均采用双环圆形外固定器。皮质切开术后,所有胫骨以0.5毫米/天的速度分散20天。术后第7天、第14天和第21天在截骨部位注射PRP。在第3、4和5周,使用定量计算机断层扫描测量在牵张区形成的新骨组织的矿物密度。在第6周结束时,处死动物,并对标本进行生物力学和组织学评估。结果显微计算机断层扫描评估显示,从第3周到第6周,骨密度显著增加(PRP组和对照组分别为62.3%和43.7%)。PRP组第3、4和5周的测量值分别为416±29、487±9.9和675±37.8 HU(Hounsfield单位),而对照组分别为313、374和450 HU。在两组每周测量值的比较中,PRP组的骨密度增加高于对照组(P<0.001)。在机械测试中,PRP-组的平均扭转为46.50°,平均扭矩为0.53 Nm,而对照组的平均扭曲为19.33°,平均转矩为0.65 Nm。力学分析显示,两组的平均最大扭转角存在显著差异(P=0.024)。PRP组的4只兔子和对照组的2只兔子的愈伤组织被重塑;骨形成正常,分散的骨端完全愈合。结论本研究结果表明,在牵张成骨愈合过程中,注射PRP可增强骨再生固结,增加骨密度。
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引用次数: 2
Adequacy of spine surgery fellowship training in Turkey: Results of a survey. 土耳其脊柱外科奖学金培训的充分性:一项调查的结果。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2022.21211
Kadir Abul
OBJECTIVEThe aim of this study was to determine the adequacy of spine surgery fellowship training (SSFT) in Turkey and what is needed for further development by interviewing current fellows.METHODSForty male orthopaedics and traumatology or neurosurgery specialists who had completed SSFT in three different spine centers in Turkey between 2010 and 2018 were asked to complete a survey with 29 questions about SSFT in Turkey. Thirty specialists responded, and the collected data were analyzed.RESULTSTwenty-seven (90%) participants were orthopaedic and traumatology specialists and three (10%) were neurosurgery specialists, with a mean age of 39 (range = 35-53) years. Most participants received their residency training in the provinces where their fellowship training took place (11 (37%) in İstanbul and 7 (23%) in Ankara). The mean duration between residency training and the start of SSFT was 4 (range = 0-14) years, and the mean SSFT duration was 8 (range = 1-18) months. Seventy percent of participants had participated in spine surgery cases during their residency. Twenty-three (77%) participants reported that spine surgery training in their hospital during their residency was inadequate. Seventeen (57%) participants felt that they could not independently perform spine surgery cases before SSFT. All three centers (100%) participating in the study that offered SSFT were non-public institutions such as private hospitals and private university hospitals of medicine managed by a dedicated mentor with personal commitment, without any accreditation for SSFT. While 25 (83%) participants indicated that they felt competent enough to perform a standard spinal deformity surgery case independently at the end of SSFT, 5 (17%) indicated the opposite. This proportion, which was 43% at the end of residency, increased to 83% after SSFT.CONCLUSIONThe results of this study have demonstrated the importance of SSFT in spine surgery as a specialty with a potentially high risk of complications that require prolonged case observation, challenging work-up, and adequate equipment. In this regard, there is a need for regulations on accreditation in government health facilities that provide ideal conditions. We propose to offer SSFT to all surgeons interested in spine surgery in Turkey by conducting further studies supported by an optimal health sector that ensures the appropriate requirements, in accordance with the declaration of TOTEK (The Turkish Orthopaedics and Traumatology Education Council), training workshops, and an accredited master's degree program in spine surgery or subspecialty.
目的:本研究的目的是通过采访目前的研究人员来确定土耳其脊柱外科研究人员培训(SSFT)的充分性以及进一步发展的需要。方法对2010年至2018年间在土耳其三家不同脊柱中心完成SSFT的40名男性骨科、创伤学或神经外科专家进行调查,其中包含29个问题。30位专家回答了问题,并对收集的数据进行了分析。结果骨科创伤专科27例(90%),神经外科专科3例(10%),平均年龄39岁(35 ~ 53岁)。大多数参与者在其研究金培训所在的省份接受住院医师培训(İstanbul有11人(37%),安卡拉有7人(23%))。从住院医师培训到SSFT开始的平均时间为4年(范围= 0-14),SSFT的平均时间为8个月(范围= 1-18)。70%的参与者在住院期间参与过脊柱手术。23名(77%)参与者报告说,他们住院期间在医院接受的脊柱外科培训不足。17例(57%)患者认为在SSFT前不能独立完成脊柱外科手术。参与研究提供SSFT的所有三个中心(100%)都是非公立机构,如私立医院和私立大学医学医院,由一位有个人承诺的专职导师管理,没有任何SSFT认证。虽然25名(83%)参与者表示他们觉得自己有足够的能力在SSFT结束时独立进行标准的脊柱畸形手术,但5名(17%)表示相反。这一比例在实习结束时为43%,在SSFT后增加到83%。结论:本研究的结果证明了SSFT在脊柱外科中的重要性,因为它具有潜在的高并发症风险,需要长时间的病例观察,具有挑战性的检查和足够的设备。在这方面,有必要制定规定,对提供理想条件的政府卫生设施进行认证。我们建议为所有对土耳其脊柱外科感兴趣的外科医生提供SSFT,根据TOTEK(土耳其骨科和创伤学教育委员会)的声明,在最佳卫生部门的支持下进行进一步的研究,确保适当的要求,培训研讨会,以及认可的脊柱外科或亚专业硕士学位课程。
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引用次数: 0
Is elective surgery during the COVID-19 pandemic safe? A multi-center prospective study in a high incidence area. COVID-19大流行期间的选择性手术安全吗?一项高发病率地区的多中心前瞻性研究。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2021.21153
S. Sastre, M. Jornet-Gibert, C. Yela-Verdú, Irene Portas-Torres, M. Balaguer-Castro, Silvia M Miguela, G. Claret, Laia Brunet, P. Torner
OBJECTIVEThe aim of this study was to describe the evolution of patients admitted for elective orthopaedic surgery during the immediate post-COVID-19 peak of the pandemic.METHODSThis is a multi-center, observational study conducted in 8 high complexity hospitals of Catalonia, one of the highest COVID-19 incidence areas in Spain. We included patients ≥18 years of age undergoing elective surgery (total knee or hip arthroplasty, knee or hip revision arthroplasty, shoulder or knee arthroscopy, hand or wrist surgery, forefoot surgery, or hardware removal) after the COVID-19 peak (between May 5th and June 30th, 2020). The main exclusion criterion was a positive result for SARS-CoV-2 PCR within the 7 days before the surgery. The primary outcomes were postoperative complications within 60 days (+/-30) or hospital readmission due to a COVID-19 infection. Following the recommendations of the International Consensus Group (ICM), elective surgeries were re-started when the nationwide lockdown was lifted. Before the surgery, patients were contacted by phone to rule out any exposure to confirmed COVID-19 cases, a reverse transcription-polymerase chain reaction (PCR) assay was performed in all patients 48-72 hours before hospital admission, and they were asked to maintain home confinement until the day of the surgery.RESULTS675 patients were included: 189 patients in the arthroplasty group (28%) and 486 in the ambulatory surgery group (72%). Mean [SD] age was 57.6 [15.3] years. The mean Charlson Comorbidity Index score was 2.21 (SD = 2.01, Min = 0, Max = 13). A total of 84 patients (12.75%) obtained an American Society of Anesthesiologists (ASA) score ≥ 3, showing no association between the ASA score and the risk of developing COVID-19 symptoms at follow-up (χ 2 (4) = 0.77, P = 0.94). The mean occupation rate of hospital beds for COVID-19 patients was 13% and the mean occupation rate of critical care beds for COVID-19 patients was 27% at the time of re-introducing elective surgeries. These were important rates to consider to decide when to reintroduce elective surgeries after lockdown. Surgical time, time of ischemia and intra-operative bleeding were not related with a higher risk of developing COVID-19 post-operatively (χ 2 (1) = 0.00, P = 0.98); (χ 2 (2) = 2.05, P = 0.36); (χ 2 (2) = 0.37, P = 0.83). Only 2 patients (0.3 %) presented with a suspected COVID-19 infection at follow-up. None of them presented with pneumonia or required confirmation by a reverse transcription PCR assay. Hospital re-admission was not needed for these patients.CONCLUSIONThe risk of developing COVID-19 during the immediate post-COVID-19 peak in a region with a high incidence of COVID-19 has not been proved. These data suggest that elective orthopaedic surgeries can be resumed when assertive and strict protocols are followed.
目的本研究的目的是描述在COVID-19大流行高峰后不久接受选择性整形外科手术的患者的演变。方法这是一项多中心观察性研究,在西班牙新冠肺炎发病率最高的地区之一加泰罗尼亚的8家高复杂度医院进行。我们包括在新冠肺炎高峰(2020年5月5日至6月30日)后接受择期手术(全膝或髋关节置换术、膝或髋翻修术、肩或膝关节镜检查、手或腕关节手术、前掌手术或硬件移除)的≥18岁的患者。主要排除标准是手术前7天内严重急性呼吸系统综合征冠状病毒2型聚合酶链式反应阳性。主要结果是术后60天内并发症(+/-30)或因新冠肺炎感染再次入院。根据国际共识小组(ICM)的建议,在全国解除封锁后,择期手术重新开始。手术前,通过电话联系患者,以排除任何接触新冠肺炎确诊病例的可能性,在入院前48-72小时对所有患者进行逆转录聚合酶链式反应(PCR)检测,并要求他们在家隔离至手术当天。结果75例患者包括:关节成形术组189例(28%)和门诊手术组486例(72%)。平均[SD]年龄为57.6[15.3]岁。Charlson合并症指数平均得分为2.21(SD=2.01,Min=0,Max=13)。共有84名患者(12.75%)获得美国麻醉医师协会(ASA)评分≥3,ASA评分与随访时出现新冠肺炎症状的风险无关(,P=0.94)。在重新引入选择性手术时,新冠肺炎患者的医院床位平均占用率为13%,新冠肺炎患者的重症监护病床平均占用率是27%。在决定封锁后何时重新引入选择性手术时,这些都是需要考虑的重要比率。手术时间、缺血时间和术中出血与术后发生新冠肺炎的高风险无关(X2(1)=0.00,P=0.98);(χ2(2)=2.05,P=0.36);(2)=0.37,P=0.83)。随访时仅有2例(0.3%)患者出现疑似新冠肺炎感染。他们中没有一人出现肺炎或需要通过逆转录聚合酶链式反应检测进行确认。这些病人不需要再次入院。结论在新冠肺炎发病率高的地区,在新冠肺炎疫情后的高峰期间发展新冠肺炎的风险尚未得到证实。这些数据表明,当遵循果断和严格的方案时,可以恢复选择性骨科手术。
{"title":"Is elective surgery during the COVID-19 pandemic safe? A multi-center prospective study in a high incidence area.","authors":"S. Sastre, M. Jornet-Gibert, C. Yela-Verdú, Irene Portas-Torres, M. Balaguer-Castro, Silvia M Miguela, G. Claret, Laia Brunet, P. Torner","doi":"10.5152/j.aott.2021.21153","DOIUrl":"https://doi.org/10.5152/j.aott.2021.21153","url":null,"abstract":"OBJECTIVE\u0000The aim of this study was to describe the evolution of patients admitted for elective orthopaedic surgery during the immediate post-COVID-19 peak of the pandemic.\u0000\u0000\u0000METHODS\u0000This is a multi-center, observational study conducted in 8 high complexity hospitals of Catalonia, one of the highest COVID-19 incidence areas in Spain. We included patients ≥18 years of age undergoing elective surgery (total knee or hip arthroplasty, knee or hip revision arthroplasty, shoulder or knee arthroscopy, hand or wrist surgery, forefoot surgery, or hardware removal) after the COVID-19 peak (between May 5th and June 30th, 2020). The main exclusion criterion was a positive result for SARS-CoV-2 PCR within the 7 days before the surgery. The primary outcomes were postoperative complications within 60 days (+/-30) or hospital readmission due to a COVID-19 infection. Following the recommendations of the International Consensus Group (ICM), elective surgeries were re-started when the nationwide lockdown was lifted. Before the surgery, patients were contacted by phone to rule out any exposure to confirmed COVID-19 cases, a reverse transcription-polymerase chain reaction (PCR) assay was performed in all patients 48-72 hours before hospital admission, and they were asked to maintain home confinement until the day of the surgery.\u0000\u0000\u0000RESULTS\u0000675 patients were included: 189 patients in the arthroplasty group (28%) and 486 in the ambulatory surgery group (72%). Mean [SD] age was 57.6 [15.3] years. The mean Charlson Comorbidity Index score was 2.21 (SD = 2.01, Min = 0, Max = 13). A total of 84 patients (12.75%) obtained an American Society of Anesthesiologists (ASA) score ≥ 3, showing no association between the ASA score and the risk of developing COVID-19 symptoms at follow-up (χ 2 (4) = 0.77, P = 0.94). The mean occupation rate of hospital beds for COVID-19 patients was 13% and the mean occupation rate of critical care beds for COVID-19 patients was 27% at the time of re-introducing elective surgeries. These were important rates to consider to decide when to reintroduce elective surgeries after lockdown. Surgical time, time of ischemia and intra-operative bleeding were not related with a higher risk of developing COVID-19 post-operatively (χ 2 (1) = 0.00, P = 0.98); (χ 2 (2) = 2.05, P = 0.36); (χ 2 (2) = 0.37, P = 0.83). Only 2 patients (0.3 %) presented with a suspected COVID-19 infection at follow-up. None of them presented with pneumonia or required confirmation by a reverse transcription PCR assay. Hospital re-admission was not needed for these patients.\u0000\u0000\u0000CONCLUSION\u0000The risk of developing COVID-19 during the immediate post-COVID-19 peak in a region with a high incidence of COVID-19 has not been proved. These data suggest that elective orthopaedic surgeries can be resumed when assertive and strict protocols are followed.","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 1 1","pages":"14-19"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49116920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The load transfer effect of monopolar and bipolar radial head prosthesis designs on capitellar cartilage: A comparative biomechanical cadaver study. 单极和双极桡骨头假体在小头软骨上的负荷转移效果:一项比较生物力学的尸体研究。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2021.20410
M. Aşık, Mehmet Akdemir, N. Turgut, Abdullah Meriç Ünal, M. Özkan, A. Ekin
OBJECTIVEThe aim of this study was to determine whether bipolar radial head arthroplasty may transfer less load to the capitellum than monopolar radial head arthroplasty and native radial heads.METHODSSix human elbow joints were obtained from six fresh frozen cadavers (3 males, 3 females; mean age = 78 years, age range = 66-80). None of the elbow joints had a previous osseous injury, a chondral defect, osteoarthritis, or instability. In group 1, load transfer of the native radial head was measured in each specimen under 100 N of compression force using a custom-made load cell at 0°, 30°, 60°, 90°, and 120° flexion of the elbow in supination, neutral rotation, and pronation, respectively. After excision of the radial heads, the same testing protocol was first applied for monopolar radial head arthroplasty (Group 2) and then for bipolar radial head arthroplasty (Group 3).RESULTSThe mean load transfer on the capitellum was significantly higher in each forearm rotation and all angles of the elbow flexion in the arthroplasty groups than the native radial head group. Mean load transfer values of bipolar prostheses were between the values of native radial heads and monopolar prostheses in all positions. Bipolar prostheses showed similar load transfer characteristics compared to those of the native radial head in supination at 60° flexion; in neutral rotation at 0°, 30°, 60°, and 120° flexion; and in pronation at 90° and 120° flexion.CONCLUSIONThe results of this study have revealed that bipolar radial head arthroplasty transfers similar loading as the native radial head on the capitellum in certain forearm positions and at elbow flexion angles. No significant differences could be found between load transfer values of bipolar head design and monopolar head design except in the pronation at full extension.
目的本研究的目的是确定双极桡骨头置换术是否比单极桡骨头置换术和原生桡骨头转移到肱骨小头的负荷更少。方法6例新鲜冷冻尸体肘关节(男3例,女3例;平均年龄78岁,年龄范围66-80岁)。所有肘关节均无骨损伤、软骨缺损、骨关节炎或不稳定性。在第1组中,在肘关节旋后、中性旋转和旋前分别为0°、30°、60°、90°和120°弯曲时,使用定制的称重传感器测量每个标本在100 N压缩力下的原生桡骨头载荷传递。切除桡骨头后,首先采用相同的测试方案进行单极桡骨头置换术(组2),然后进行双极桡骨头置换术(组3)。结果关节置换术组在每次前臂旋转和肘关节屈曲的各个角度上对小头的平均负荷转移明显高于原始桡骨头组。双极假体在所有位置的平均载荷传递值介于天然桡骨头和单极假体之间。双极假体在旋后60°屈曲时表现出与天然桡骨头相似的负荷传递特性;在0°,30°,60°和120°屈曲中性旋转;在旋前90°和120°屈曲处。结论本研究结果表明,双极桡骨头置换术在前臂的某些位置和肘关节屈曲角度上转移的载荷与天然桡骨头相似。双极头设计和单极头设计的载荷传递值除了完全伸展时的旋前外,没有显著差异。
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引用次数: 0
The efficacy of angiotensin-converting enzyme inhibitors in preventing postoperative tendon adhesion formation: An experimental study in rats. 血管紧张素转换酶抑制剂预防大鼠术后肌腱粘连形成的疗效:一项实验研究。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2022.21231
Tuğçe Yasak, Ö. Özkaya, Ayça Ergan Şahin, Özden Aksu Sayman, E. Bozdag
OBJECTIVEThe aim of this study was to investigate the efficacy of angiotensin-converting enzyme inhibitors (ACEIs) in preventing postoperative tendon adhesion formation in a rat model of Achilles tendon repair.METHODSIn this study, 60 Sprague-Dawley male rats weighing 300 to 350 g were used. Rats were randomly divided into six groups (n = 10 per group): control-1, control-2, sham-1, sham-2, experiment-1, and experiment-2. The same surgical procedure was performed in all rats; a full thickness Achilles tenotomy was performed, and the tendon was repaired using a modified Kessler suture. Enalapril (10 mg/kg/day) was orally given to the Experiment-1 and Experiment-2 groups for three and six weeks, respectively. Thirty rats were sacrificed at three weeks (Control-1, Sham-1, Experiment-1); the remaining 30 rats were sacrificed at six weeks (Control-2, Sham-2, Experiment-2). Then, macroscopic, biomechanical, and histologic investigations were performed.RESULTSAdhesion degree was found macroscopically lower in the Experiment-1 and 2 groups than others. In the histologic examination, the fibrosis level was found the lowest in the Experiment-2 group. Biomechanical evaluation indicated that mean maximum resistance before tendon rupture was significantly higher in the Experiment-2 group than in other groups.CONCLUSIONEvidence from this study has shown that ACEIs can decrease fibrosis and tendon adhesion during tendon recovery in rats due to their antifibrotic effects as the result of Angiotensin-II suppression.
目的研究血管紧张素转换酶抑制剂(ACEIs)在大鼠跟腱修复模型中预防术后肌腱粘连形成的疗效。方法本研究选用60只Sprague-Dawley雄性大鼠,体重300~350g。大鼠被随机分为六组(每组n=10):对照-1、对照-2、sham-1、sham-2、实验-1和实验-2。对所有大鼠进行相同的外科手术;进行全厚度跟腱切开术,并使用改良的Kessler缝线修复肌腱。实验-1组和实验-2组分别口服依那普利(10mg/kg/天)3周和6周。在三周时处死30只大鼠(对照-1,Sham-1,实验-1);其余30只大鼠在6周时处死(对照-2,Sham-2,实验-2)。然后进行宏观、生物力学和组织学研究。结果实验1组和实验2组的粘连程度在宏观上低于其他组。在组织学检查中,发现实验-2组的纤维化水平最低。生物力学评估表明,实验-2组肌腱断裂前的平均最大阻力明显高于其他组。结论本研究的证据表明,血管紧张素II抑制剂具有抗纤维化作用,可降低大鼠肌腱恢复过程中的纤维化和肌腱粘连。
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引用次数: 1
Tibial slope changes following guided growth by the eight-plate: A retrospective comparative study. 八块钢板引导生长后胫骨斜率的变化:一项回顾性比较研究。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2022.20365
Vahit Yıldız, E. Cullu
OBJECTIVEThe aims of this study were (1) to investigate the tibial slope (TS) changes following guided growth by the eight-plate and to determine the relationship between the TS change in the sagittal plane and the plate position.METHODSIn this retrospective study, children who underwent guided growth by the eight-plate for genu varum or valgum were included. Thirty-eight extremities of 23 children (14 girls and 9 boys; mean age = 9.2 years, age range = 3-17 years) were then divided into two groups according to the plate location in the sagittal plane (anterior or midline). Preoperative and postoperative TS were measured from the medial and lateral tibial plateaus separately.RESULTSThe mean follow-up was 34.3 (range = 12-96) months. The mean preoperative and postoperative medial TS were 4.05 ± 5.65 and 0.83 ± 3.91 degrees, respectively, in 18 patients in whom anterior epiphyseal plates were placed (P = 0.004). The mean preoperative and postoperative lateral TS were 4.88 ± 5.33 and 0.11 ± 3.34 degrees, respectively, in 18 patients in whom anterior epiphyseal plates were placed (P < 0.001). The mean preoperative and postoperative medial TS were 4.2 ± 5.19 and 4.9 ± 6.02 degrees, respectively, in 20 patients in whom midline epiphyseal plates were placed (P = 0.532). The mean preoperative and postoperative lateral TS were 5 ± 5.51 and 4.8 ± 5.7 degrees, respectively, in 20 patients in whom midline epiphyseal plates were placed (P = 0.871). Postoperative TS was decreased in anteriorly located eight-plates, and medial and lateral plateau measurement was significant (P = 0.004 and P < 0.001, respectively). Postoperative TS changes in midline-placed eight-plates were not significant regarding the medial and lateral plateaus (P = 0.532 and P = 0.871, respectively).CONCLUSIONThe results of this study have shown that TS decreases following guided growth by the eight-plate in children in whom plates are placed at the anterior epiphysis. To prevent TS changes, the eight-plate should be placed in the midline position at the sagittal plane.LEVEL OF EVIDENCELevel IV, Therapeutic Study.
目的本研究的目的是:(1)研究8钢板引导生长后胫骨斜率(TS)的变化,并确定矢状面TS变化与钢板位置的关系。方法回顾性研究采用8钢板治疗膝内翻或外翻的患儿。23名儿童38个四肢(14名女孩,9名男孩;平均年龄= 9.2岁,年龄范围= 3-17岁),然后根据钢板在矢状面(前或中线)的位置分为两组。术前和术后分别从胫骨内侧和外侧平台测量TS。结果平均随访34.3个月(范围12 ~ 96个月)。18例置入前骺板患者术前、术后内侧TS平均值分别为4.05±5.65度和0.83±3.91度(P = 0.004)。18例置入前骺板患者术前、术后侧位TS平均值分别为4.88±5.33度和0.11±3.34度(P < 0.001)。放置中线骺板的20例患者,术前、术后平均TS分别为4.2±5.19度和4.9±6.02度(P = 0.532)。20例中线骺板置入患者术前、术后侧位TS平均值分别为5±5.51度和4.8±5.7度(P = 0.871)。术后位于前方的8块钢板TS降低,内侧和外侧平台测量值显著(P = 0.004和P < 0.001)。中线放置的8块钢板术后内侧和外侧平台的TS变化不显著(P = 0.532和P = 0.871)。结论:本研究结果表明,在骨骺前部放置钢板的儿童中,经8钢板引导生长后,TS降低。为防止TS改变,八钢板应放置在矢状面中线位置。证据水平:IV级,治疗性研究。
{"title":"Tibial slope changes following guided growth by the eight-plate: A retrospective comparative study.","authors":"Vahit Yıldız, E. Cullu","doi":"10.5152/j.aott.2022.20365","DOIUrl":"https://doi.org/10.5152/j.aott.2022.20365","url":null,"abstract":"OBJECTIVE\u0000The aims of this study were (1) to investigate the tibial slope (TS) changes following guided growth by the eight-plate and to determine the relationship between the TS change in the sagittal plane and the plate position.\u0000\u0000\u0000METHODS\u0000In this retrospective study, children who underwent guided growth by the eight-plate for genu varum or valgum were included. Thirty-eight extremities of 23 children (14 girls and 9 boys; mean age = 9.2 years, age range = 3-17 years) were then divided into two groups according to the plate location in the sagittal plane (anterior or midline). Preoperative and postoperative TS were measured from the medial and lateral tibial plateaus separately.\u0000\u0000\u0000RESULTS\u0000The mean follow-up was 34.3 (range = 12-96) months. The mean preoperative and postoperative medial TS were 4.05 ± 5.65 and 0.83 ± 3.91 degrees, respectively, in 18 patients in whom anterior epiphyseal plates were placed (P = 0.004). The mean preoperative and postoperative lateral TS were 4.88 ± 5.33 and 0.11 ± 3.34 degrees, respectively, in 18 patients in whom anterior epiphyseal plates were placed (P < 0.001). The mean preoperative and postoperative medial TS were 4.2 ± 5.19 and 4.9 ± 6.02 degrees, respectively, in 20 patients in whom midline epiphyseal plates were placed (P = 0.532). The mean preoperative and postoperative lateral TS were 5 ± 5.51 and 4.8 ± 5.7 degrees, respectively, in 20 patients in whom midline epiphyseal plates were placed (P = 0.871). Postoperative TS was decreased in anteriorly located eight-plates, and medial and lateral plateau measurement was significant (P = 0.004 and P < 0.001, respectively). Postoperative TS changes in midline-placed eight-plates were not significant regarding the medial and lateral plateaus (P = 0.532 and P = 0.871, respectively).\u0000\u0000\u0000CONCLUSION\u0000The results of this study have shown that TS decreases following guided growth by the eight-plate in children in whom plates are placed at the anterior epiphysis. To prevent TS changes, the eight-plate should be placed in the midline position at the sagittal plane.\u0000\u0000\u0000LEVEL OF EVIDENCE\u0000Level IV, Therapeutic Study.","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 1 1","pages":"31-35"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42887340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcomes of single-bundle versus double-bundle ACL reconstruction in adolescent elite athletes: A retrospective comparative study. 青少年精英运动员单束与双束ACL重建的临床结果:一项回顾性比较研究。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2022.21048
B. Toker, T. Erden, G. Dikmen, V. E. Özden, G. Firatli, Ö. Taşer
OBJECTIVEThe aim of the study was to evaluate the single bundle (SB) and double bundle (DB) anterior cruciate ligament (ACL) reconstruction in terms of graft survival, complications, and patient reported functional outcomes in adolescent athletes.METHODSIn this retrospective study, 89 elite adolescent athletes who underwent either SB or DB ACL reconstruction were included. All patients were then divided into two groups: group 1 including 51 patients with SB ACL reconstruction (31 male, 20 female; mean age = 15.4 ± 1.03 years) and group 2 including 38 patients with DB ACL (30 male, 8 female; mean age = 15.7 ± 1.3 years). Clinical data were obtained, comprising skeletal maturity, sports type, ACL reconstruction technique, Lachman scores, KT-1000™ arthrometer measurement, additional meniscal procedures as well as International Knee Documentation Committee (IKDC) score, Cincinnati score, and graft size.RESULTSThe mean follow-up period was 53.1 ± 8.6 months in group 1 and 46.4± 9.1 months in group 2 (P = 0.61). The type of ACL reconstruction technique (SB or DB), gender, skeletal maturity, sports type, additional meniscal procedures and Lachman scores were not associated with the re-rupture of the ACL (P > 0.05). Moreover, ACL reconstruction technique did not effect the rate of re-rupture of an ACL. There were 21 re-ruptures (23.5%) and 11 (12.3%) contralateral ACL ruptures in total. Among 21 reruptures, 12 of them were in the DB group while nine of them in the SB group (P > 0.05). The groups did not differ with respect to age, the injured side, the time from injury to surgery, the postoperative follow-up time, or the preoperative physical examination results KT-1000 device (SSD), Cincinnati score, IKDC objective and subjective score,Lachman test and pivot-shift test).CONCLUSIONThere are no differences in the re-rupture of an ACL, patient reported outcomes, and complications in adolescent elite players, when either an SB or DB technique is performed.LEVEL OF EVIDENCELevel III, Therapeuthic Study.
目的:本研究旨在评估青少年运动员单束(SB)和双束(DB)前交叉韧带(ACL)重建在移植物存活、并发症和患者报告的功能结局方面的影响。方法回顾性研究89例优秀青少年运动员行前交叉韧带重建。然后将所有患者分为两组:1组51例行SB前交叉韧带重建(男31例,女20例;平均年龄= 15.4±1.03岁),第二组包括38例DB ACL患者(男性30例,女性8例;平均年龄= 15.7±1.3岁)。获得临床数据,包括骨骼成熟度、运动类型、ACL重建技术、Lachman评分、KT-1000™关节计测量、附加半月板手术以及国际膝关节文献委员会(IKDC)评分、辛辛那提评分和移植物大小。结果1组患者平均随访时间为53.1±8.6个月,2组患者平均随访时间为46.4±9.1个月(P = 0.61)。ACL重建技术类型(SB或DB)、性别、骨骼成熟度、运动类型、额外半月板手术和Lachman评分与ACL再破裂无关(P < 0.05)。此外,ACL重建技术对ACL再破裂率没有影响。对侧ACL断裂21例(23.5%),11例(12.3%)。21例复发患者中,DB组12例,SB组9例(P < 0.05)。各组在年龄、损伤侧、损伤至手术时间、术后随访时间、术前体检结果(KT-1000设备(SSD)、Cincinnati评分、IKDC客观和主观评分、Lachman检验和pivot-shift检验)等方面均无差异。结论:在青少年优秀球员中,采用SB或DB技术,在ACL再破裂、患者报告的结果和并发症方面没有差异。证据等级:III级,治疗研究。
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引用次数: 2
Preliminary results of iliosacral screws and plate combination in the management of tile B3 pelvic fractures: A retrospective case series. 髂骶骨螺钉和钢板组合治疗B3型骨盆骨折的初步结果:一个回顾性病例系列。
IF 1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2022-01-01 DOI: 10.5152/j.aott.2022.19233
Yi-Bing Zheng, Yi-Hong Yin, Wei-Bin Wang, Qing-Song Fu, Xinhua Yuan
OBJECTIVEThe aim of this study was to present preliminary results and experience with iliosacral screws and plate combination (horizontal triangular osteosynthesis, HTO) in the management of Tile B3 pelvic fractures.METHODSIn this retrospective study, 26 patients (18 male, 8 female; mean age = 46, age range = 31-58 years) who were treated with horizontal triangular osteosynthesis using the combination of bilateral percutaneous iliosacral screws and transiliac plates due to Tile B3 pelvic fractures in our institution were included. The accompanying symptoms, blood loss, operation time , fracture healing time, and postoperative complications were observed and recorded. Patients were followed up retrospectively with routine post-operation visits for clinical and radiographic examination. The reduction quality was evaluated according to Matta criterion. Clinical and nerve function outcomes were evaluated by Majeed and Gibbons criterion.RESULTSThe mean follow-up time was 15 months (range = 12-21 months). The mean blood loss and operation time were 24.6 ± 6.7mL and 30.5 ± 3.47 mins, respectively. Patients experienced early weight-bearing ability and no fracture reduction loss. Due to Matta criterion for fracture reduction, the results were excellent in 16 cases, good in 9 cases, and fair in 1 case. Due to Majeed functional scoring at the last follow-up, the results were excellent in 17 cases, good in 9 cases. Of 3 patients in whom neurologic impairment was detected preoperatively, 2 achieved complete recovery, and 1 achieved partial improvement postoperatively.CONCLUSIONAs a new surgical concept in the management of Tile B3 pelvic fractures, HTO seems to provide the following advantages: horizontal triangular fixation, minimally invasive incisions, less blood loss, and permitting early weight-bearing ability. However, there still exist several problems regarding the technique and the option of implants.LEVEL OF EVIDENCELevel IV, Therapeutic Study.
目的:本研究旨在介绍髂骶骨螺钉和钢板组合(水平三角形接骨术,HTO)治疗Tile B3骨盆骨折的初步结果和经验。方法在这项回顾性研究中,我们纳入了26名患者(18名男性,8名女性;平均年龄=46,年龄范围=31-58岁),他们在我们的机构中接受了Tile B3骨盆骨折的双侧经皮髂骶骨螺钉和透明钢板组合的水平三角形接骨术。观察并记录伴随症状、失血量、手术时间、骨折愈合时间及术后并发症。对患者进行回顾性随访,进行常规术后临床和放射学检查。还原质量根据Matta标准进行评估。临床和神经功能结果采用Majeed和Gibbons标准进行评估。结果平均随访时间为15个月(12~21个月)。平均失血量和手术时间分别为24.6±6.7mL和30.5±3.47min。患者经历了早期的负重能力,没有骨折复位损失。根据Matta骨折复位标准,优16例,良9例,尚可1例。由于上次随访时Majeed功能评分,17例结果良好,9例结果良好。术前发现神经损伤的3例患者中,2例完全康复,1例术后部分好转。结论HTO作为治疗Tile B3骨盆骨折的一种新的手术理念,似乎具有以下优点:水平三角形固定、微创切口、较少出血和允许早期负重能力。然而,在植入物的技术和选择方面仍然存在一些问题。证据水平第四级,治疗研究。
{"title":"Preliminary results of iliosacral screws and plate combination in the management of tile B3 pelvic fractures: A retrospective case series.","authors":"Yi-Bing Zheng, Yi-Hong Yin, Wei-Bin Wang, Qing-Song Fu, Xinhua Yuan","doi":"10.5152/j.aott.2022.19233","DOIUrl":"https://doi.org/10.5152/j.aott.2022.19233","url":null,"abstract":"OBJECTIVE\u0000The aim of this study was to present preliminary results and experience with iliosacral screws and plate combination (horizontal triangular osteosynthesis, HTO) in the management of Tile B3 pelvic fractures.\u0000\u0000\u0000METHODS\u0000In this retrospective study, 26 patients (18 male, 8 female; mean age = 46, age range = 31-58 years) who were treated with horizontal triangular osteosynthesis using the combination of bilateral percutaneous iliosacral screws and transiliac plates due to Tile B3 pelvic fractures in our institution were included. The accompanying symptoms, blood loss, operation time , fracture healing time, and postoperative complications were observed and recorded. Patients were followed up retrospectively with routine post-operation visits for clinical and radiographic examination. The reduction quality was evaluated according to Matta criterion. Clinical and nerve function outcomes were evaluated by Majeed and Gibbons criterion.\u0000\u0000\u0000RESULTS\u0000The mean follow-up time was 15 months (range = 12-21 months). The mean blood loss and operation time were 24.6 ± 6.7mL and 30.5 ± 3.47 mins, respectively. Patients experienced early weight-bearing ability and no fracture reduction loss. Due to Matta criterion for fracture reduction, the results were excellent in 16 cases, good in 9 cases, and fair in 1 case. Due to Majeed functional scoring at the last follow-up, the results were excellent in 17 cases, good in 9 cases. Of 3 patients in whom neurologic impairment was detected preoperatively, 2 achieved complete recovery, and 1 achieved partial improvement postoperatively.\u0000\u0000\u0000CONCLUSION\u0000As a new surgical concept in the management of Tile B3 pelvic fractures, HTO seems to provide the following advantages: horizontal triangular fixation, minimally invasive incisions, less blood loss, and permitting early weight-bearing ability. However, there still exist several problems regarding the technique and the option of implants.\u0000\u0000\u0000LEVEL OF EVIDENCE\u0000Level IV, Therapeutic Study.","PeriodicalId":7097,"journal":{"name":"Acta orthopaedica et traumatologica turcica","volume":"56 1 1","pages":"48-52"},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43721555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Acta orthopaedica et traumatologica turcica
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