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Age Differences in Patients With Postoperative Pain and Their Relationships to Comorbid Conditions: Multivariate Logistic Regression Analysis. 术后疼痛患者的年龄差异及其与合并症的关系:多因素Logistic回归分析。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001024
Lisiane Pruinelli, Michelle A Mathiason, Sisi Ma, Nicholas Stalter, Laura Stone, Roger B Fillingim, Sudarshan Setty, Ratan K Banik

This study analyzed the relationship between aging and reported pain during the acute postoperative period in a retrospective analysis of 2,600 adult patients who underwent abdominal surgeries. Data included demographics, diagnoses, surgical, and pain assessments. Severe pain was defined as reported pain intensity ≥ 7 on the numeric rating score during the first 24 hours postsurgery. Patients were grouped into three different age categories: 18-44, 45-64, and ≥ 65 years. Comparisons among groups were performed using the Chi-square test. Multivariate logistic regression was used to estimate the likelihood of patients reporting pain intensity ≥ 7. The likelihood of reporting severe pain was significantly lower in older (> 65 years; OR, 0.48; CI, 0.39-0.60) and middle-aged (45-64 years; OR, 0.77; CI, 0.63-0.91) patients as compared with younger patients (18-44 years). Factors increasing the likelihood of reporting severe pain included female sex (OR, 1.34; CI, 1.13-1.58), history of chronic pain (OR, 2.03; CI, 1.58-2.60), and incidence of depression and/or anxiety (OR, 1.65; CI, 1.29-2.12). Findings suggest that patients ≥ 65 years are significantly less likely to experience severe acute postoperative pain following a major abdominal surgery. Nurse anesthetists' awareness of age-specific acute postoperative pain management can lead to better patient pain outcomes.

本研究通过对2600例接受腹部手术的成年患者进行回顾性分析,分析了衰老与术后急性期疼痛之间的关系。数据包括人口统计、诊断、手术和疼痛评估。重度疼痛定义为术后24小时内报告的疼痛强度≥7。患者分为3个不同的年龄组:18-44岁、45-64岁和≥65岁。组间比较采用卡方检验。采用多变量logistic回归估计患者报告疼痛强度≥7的可能性。与年轻患者(18-44岁)相比,老年患者(50 - 65岁;OR, 0.48; CI, 0.39-0.60)和中年患者(45-64岁;OR, 0.77; CI, 0.63-0.91)报告剧烈疼痛的可能性显着降低。增加报告严重疼痛可能性的因素包括女性(OR, 1.34; CI, 1.13-1.58)、慢性疼痛史(OR, 2.03; CI, 1.58-2.60)和抑郁和/或焦虑的发生率(OR, 1.65; CI, 1.29-2.12)。研究结果表明,≥65岁的患者在腹部大手术后出现严重急性术后疼痛的可能性明显降低。护理麻醉师对年龄特异性急性术后疼痛管理的认识可以导致更好的患者疼痛结果。
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引用次数: 0
Balancing Risks in Obstetrics: Anesthesia Management in Facioscapulohumeral Muscular Dystrophy with Scoliosis. 平衡产科风险:面部肩胛骨肱肌营养不良伴脊柱侧凸的麻醉管理。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001035
Ashwin Mani, Sukriti Jha, Vinay Kumar, Shailendra Kumar

Facioscapulohumeral muscular dystrophy (FSHD), the third most common form of muscular dystrophy, is associated with a normal life expectancy, resulting in more pregnant women presenting with the condition. Pregnancy often exacerbates muscle weakness in patients with FSHD, posing unique perioperative challenges. Careful evaluation of systemic involvement is essential to minimize maternal and neonatal risks. Perioperative management is often challenging because both general and neuraxial anesthesia carry significant risks. Spinal deformities further complicate anesthesia management, requiring troubleshooting. Apart from these challenges, literature on managing FSHD during cesarean sections is limited. We report the successful anesthetic management of an elective cesarean section in a patient with FSHD and scoliosis, reviewing troubleshooting measures for neuraxial blocks in spinal deformities.

面肩肱骨肌营养不良症(FSHD)是第三种最常见的肌肉营养不良症,与正常的预期寿命有关,导致更多的孕妇出现这种情况。妊娠常常加剧FSHD患者的肌肉无力,形成独特的围手术期挑战。仔细评估全身受累是必要的,以尽量减少产妇和新生儿的风险。围手术期管理通常具有挑战性,因为全身麻醉和轴向麻醉都有很大的风险。脊柱畸形进一步使麻醉管理复杂化,需要排除故障。除了这些挑战之外,关于剖宫产术中处理FSHD的文献是有限的。我们报道了一例伴有FSHD和脊柱侧凸的患者择期剖宫产手术的成功麻醉处理,回顾了脊柱畸形中神经轴阻滞的诊断措施。
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引用次数: 0
Endotracheal Tube Replacement in the Prone Position With Intubating Laryngeal Mask Airway/Flexible Fiberoptic Scope Combination or Glidescope® Video Laryngoscope: A Manikin-Based Study. 俯卧位气管内插管与气管面罩气道/柔性纤维镜组合或滑梯镜®视频喉镜:一项基于人体模型的研究。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001001
Abigail Villareal, Alejandro Ruiz de Somocurcio, Caleb Schauweker, Ron Fisher, Brian Cornelius

Placing patients in the prone position is required for many surgical procedures. However, once in this position, the endotracheal tube (ETT) is often inaccessible to providers and accidental removal in an anesthetized, surgical patient can pose a life-threatening emergency. This experimental study aimed to examine the effectiveness of endotracheal reintubation in the prone position using a video laryngoscope (Glidescope®) compared with an intubating laryngeal mask airway (LMA) with ETT placement assisted by fiberoptic scope on a manikin. This study was conducted using 30 anesthesia providers with varying degrees of experience. The median times to intubation were lower using the Glidescope (73.5 s vs 130 s; P < .001). Moreover, the use of the Glidescope resulted in no esophageal intubations as well as fewer attempts than when using the LMA. Most anesthesia providers found that the Glidescope was the easiest technique to perform and learn. Despite these positive outcomes for the Glidescope, most of the participants reported the use of the LMA as a safer choice because of its capability to ventilate the manikin quickly (mean time to ventilation 12.13 s). The Glidescope method was found to be more likely to cause dental damage. The most important strategy is development of a plan prior to the emergent need.

许多外科手术都需要将患者置于俯卧位。然而,一旦在这个位置,气管内管(ETT)往往是无法接近的提供者和意外拔出的麻醉手术患者可能会造成危及生命的紧急情况。本实验研究旨在检验在俯卧位下使用视频喉镜(Glidescope®)进行气管内再插管的有效性,并与在光纤镜辅助下放置ETT的气管插管喉罩气道(LMA)进行比较。本研究由30名经验不同的麻醉提供者进行。Glidescope插管的中位时间较低(73.5 s vs 130 s; P < 0.001)。此外,与使用LMA相比,Glidescope的使用没有导致食管插管以及更少的尝试。大多数麻醉提供者发现滑翔镜是最容易操作和学习的技术。尽管Glidescope有这些积极的结果,但大多数参与者报告使用LMA是一个更安全的选择,因为它能够快速给人体模型通风(平均通风时间12.13 s)。Glidescope方法被发现更容易造成牙齿损伤。最重要的策略是在紧急需要之前制定计划。
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引用次数: 0
Methadone or Buprenorphine: Equal in Treating Opioid Dependent Parturients? 美沙酮或丁丙诺啡:治疗阿片类药物依赖的孕妇效果相同?
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001036
Cindi Dabney, Nicole Nelson, Michelle Canale, Sarah Jingying Zhang

Opioid use and misuse in parturients manifests in almost six out of every 1000 births, with close to 22,000 infants born annually to women using opiates. Additionally, the associated costs in managing these pregnant patients and their infants have increased to $1.5 billion annually. The American College of Obstetricians and Gynecologists currently recommends sublingual buprenorphine and oral methadone as the two opioid pharmacotherapy options for the treatment of opioid use disorder in pregnant patients. However, the pharmacology of buprenorphine and methadone differs greatly, making initiation and management of these two medications complex. Thus, it is crucial for anesthesia providers and obstetrical teams to have a thorough understanding of these two opioids and become familiarized with the current evidence-based practice for the management of parturients undergoing medication for opioid use disorder during pregnancy. In this journal course, the differences between the pharmacology of buprenorphine and methadone are described and benefits and limitations associated with the use of methadone and buprenorphine in parturients are discussed based on the current research data.

每1000名新生儿中就有近6人使用和滥用阿片类药物,每年有近2.2万名婴儿由使用阿片类药物的妇女所生。此外,管理这些孕妇及其婴儿的相关费用已增加到每年15亿美元。美国妇产科医师学会目前推荐舌下丁丙诺啡和口服美沙酮作为治疗孕妇阿片类药物使用障碍的两种阿片类药物治疗选择。然而,丁丙诺啡和美沙酮的药理学差异很大,使得这两种药物的起始和管理复杂。因此,对于麻醉提供者和产科团队来说,全面了解这两种阿片类药物并熟悉目前以证据为基础的孕妇在妊娠期间接受阿片类药物使用障碍治疗的管理实践是至关重要的。在本期刊课程中,描述了丁丙诺啡和美沙酮的药理学差异,并根据目前的研究数据讨论了美沙酮和丁丙诺啡在产妇中使用的益处和局限性。
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引用次数: 0
PrEP-ared for Surgery? A Comprehensive Narrative Review of Perioperative Recommendations for Anesthesia Providers. 准备手术了吗?对麻醉提供者围手术期建议的综合述评。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001034
Jennifer R Majumdar, Jake W Forrester, Kelly S Haviland, Christina D Massaro, John C Welch, Deirdre C Kelleher

The use of Pre-Exposure Prophylaxis (PrEP) for human immunodeficiency virus (HIV) prevention has increased significantly, with approximately 30% of eligible individuals in the U.S. receiving a prescription by 2021, up from 13% in 2017. As more patients on PrEP undergo surgical procedures, understanding the perioperative implications of these medications is crucial for anesthesia providers. This review aims to summarize current literature on the perioperative considerations for patients on PrEP and provide anesthesia providers with key recommendations to optimize patient safety and outcomes. It examines the pharmacology, side effects, and perioperative considerations of current PrEP formulations: Truvada, Descovy, and Apretude. We conducted a broad literature search focusing on publications from 2013 through 2024. The review identifies potential nephrotoxicity with tenofovir-based formulations, particularly when combined with nephrotoxic agents such as nonsteroidal anti-inflammatory drugs. Emtricitabine/tenofovir alafenamide use is associated with an increased risk of hypertension and hypercholesterolemia. No specific anesthetic agents are contraindicated, but dose adjustments for renally excreted drugs may be necessary. Current evidence supports continuing PrEP throughout the perioperative period, with strategies provided for managing different formulations during surgery. As PrEP use expands, anesthesia providers must balance safe, effective care with contributing to HIV prevention efforts. Future research should focus on long-term anesthetic implications of PrEP and optimal perioperative management strategies. By implementing informed practices, anesthesia providers can significantly enhance the care of patients on PrEP and support broader public health goals in HIV prevention.

暴露前预防(PrEP)预防人类免疫缺陷病毒(HIV)的使用显著增加,到2021年,美国约有30%的符合条件的个人获得处方,高于2017年的13%。随着越来越多接受PrEP的患者接受外科手术,了解这些药物的围手术期影响对麻醉提供者至关重要。本综述旨在总结目前关于PrEP患者围手术期注意事项的文献,并为麻醉提供者提供关键建议,以优化患者的安全性和预后。它检查了目前PrEP制剂的药理学、副作用和围手术期注意事项:特鲁瓦达、德斯科维和阿普瑞特。我们对2013年至2024年的出版物进行了广泛的文献检索。该综述确定了以替诺福韦为基础的制剂的潜在肾毒性,特别是与非甾体类抗炎药等肾毒性药物联合使用时。恩曲他滨/替诺福韦阿拉芬胺的使用与高血压和高胆固醇血症的风险增加有关。没有特定的麻醉剂是禁忌,但剂量调整肾脏排泄药物可能是必要的。目前的证据支持在围手术期继续使用PrEP,并提供了在手术期间管理不同配方的策略。随着PrEP使用的扩大,麻醉提供者必须在安全、有效的护理与促进艾滋病毒预防工作之间取得平衡。未来的研究应关注PrEP的长期麻醉意义和最佳围手术期管理策略。通过实施知情做法,麻醉提供者可以显著加强对PrEP患者的护理,并支持更广泛的艾滋病毒预防公共卫生目标。
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引用次数: 0
The Editor's Desk: The Critical Role of Peer Review: Ensuring Quality and Advancing Nurse Anesthesiology Scholarship. 编辑台:同行评议的关键作用:确保质量和推进护士麻醉学奖学金。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001059
Edwin N Aroke
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引用次数: 0
A National Survey Analysis of CRNAs' Perceived Ease of Use and Perceived Usefulness of Video Laryngoscopes for Difficult Airways. 一项全国调查分析crna对困难气道视频喉镜的感知易用性和感知有用性。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001032
Uwe Klemm

Video laryngoscopes (VLs) offer benefits by improving visualization and first-attempt success and decreasing failed intubations. This study examined the perceived usefulness and perceived ease of using VLs by certified registered nurse anesthetists (CRNAs) utilizing the Technology Acceptance Model published by Fred Davis in 1989. The study further investigated the influence of patient airway types, provider characteristics (age, years of practice, intubation frequency), and clinical factors (hospital size and technology availability) on subsequent selection and usage. The cross-sectional design included a one-time national survey using a purposive 3,000-CRNA sample. Data analysis included univariate, bivariate, and multivariate methodologies with multiple linear and binary logistic regression models. Approximately 71% of CRNAs were extremely likely to find VLs useful and easy to use and approximately 60% reported their selection and use when confronting difficult airways. Additionally, CRNAs selecting VLs for routine airways 50% to 100% of the time reported 4.49 times greater odds of always using VLs (100%) for difficult airways compared with CRNAs using this technology infrequently. This study provides current usage data by CRNAs and represents a first-ever assessment exploring CRNA perceptions of usefulness and ease in utilizing VLs in the operating room setting.

视频喉镜(VLs)通过改善可视化和首次尝试成功以及减少插管失败提供了好处。本研究利用Fred Davis于1989年发表的技术接受模型,考察了注册麻醉师(crna)使用VLs的感知有用性和感知易用性。该研究进一步调查了患者气道类型、提供者特征(年龄、从业年限、插管频率)和临床因素(医院规模和技术可用性)对后续选择和使用的影响。横断面设计包括使用有目的的3,000-CRNA样本进行一次性全国调查。数据分析包括单变量、双变量和多变量方法,采用多元线性和二元逻辑回归模型。大约71%的crna极有可能发现VLs有用且易于使用,大约60%的crna报告了他们在面对困难气道时的选择和使用。此外,与不经常使用该技术的crna相比,在常规气道中选择VLs的crna在50%至100%的时间内始终使用VLs的几率(100%)高出4.49倍。本研究提供了CRNA的当前使用数据,并首次评估了CRNA对在手术室环境中使用vl的有效性和易用性的看法。
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引用次数: 0
Training Anesthesia Providers in Gastric Ultrasound Assessment: An Integrative Review. 培训麻醉提供者在胃超声评估:综合回顾。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001037
Megan Rafferty, Aaron Turner, Eli Walch, Alexander Halstead

Point-of-care ultrasound (POCUS) is an inexpensive and often readily available tool for anesthesia providers to utilize to assess gastric content, both qualitatively and quantitatively, in the perioperative arena. Gastric POCUS requires the anesthesia provider to be trained and proficient in technique and interpretation of findings to accurately guide decision-making for patient care. The American Association of Nurse Anesthesiology, the American Society of Anesthesiologists, and the American Society of Regional Anesthesia have established guidelines supporting the use of gastric POCUS. This article aims to provide an integrative review of the literature surrounding current strategies in education and assessment of anesthesia provider competency in the perioperative utilization of gastric POCUS. Strict inclusion and exclusion criteria were used yielding eight articles in an effort to help determine feasible, efficient, reliable, and beneficial educational strategies to improve anesthesia provider competency. Findings suggest success with various educational strategies, including didactic, hands-on, electronic, and self-directed courses on gastric POCUS, supported by improved postintervention analyses of provider competency.

即时超声(POCUS)是一种廉价且易于获得的工具,用于麻醉提供者在围手术期对胃内容物进行定性和定量评估。胃POCUS需要麻醉提供者经过培训,熟练掌握技术和结果解释,以准确指导患者护理决策。美国护士麻醉学协会、美国麻醉师协会和美国区域麻醉协会已经建立了支持使用胃POCUS的指南。本文旨在对麻醉提供者在胃POCUS围手术期应用能力的教育和评估方面的当前策略进行综合综述。采用严格的纳入和排除标准,产生8篇文章,以帮助确定可行、有效、可靠和有益的教育策略,以提高麻醉提供者的能力。研究结果表明,各种教育策略,包括教学、实践、电子和自我指导的胃POCUS课程,以及改进的提供者能力干预后分析,都是成功的。
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引用次数: 0
Anesthetic Management of Elective Cesarean Delivery in a Pregnant Patient With Dilated Cardiomyopathy and Pulmonary Hypertension: A Multidisciplinary Approach. 扩张型心肌病合并肺动脉高压孕妇择期剖宫产的麻醉管理:多学科方法。
Q3 Medicine Pub Date : 2025-10-01 DOI: 10.70278/AANAJ/.0000001039
Nikolas Zoé Ferreira Santos, Caio Cesar Levate Amaral, Maurício Vitor Machado Oliveira, Marina Ayres Delgado

Peripartum cardiomyopathy (PPCM) complicated by pulmonary arterial hypertension (PAH) is an uncommon and high-risk condition that presents significant anesthetic and obstetric challenges. This case report contributes to the limited literature by describing the successful anesthetic management of a parturient with severe cardiac dysfunction and PAH, emphasizing the importance of a multidisciplinary approach. A 30-year-old pregnant woman with newly diagnosed dilated cardiomyopathy of unknown etiology and PAH was admitted for elective cesarean delivery. The diagnosis was established in the second trimester following symptoms of dyspnea at rest. Transthoracic echocardiography revealed severe left ventricular systolic dysfunction and elevated pulmonary artery pressures. A combined spinal-epidural technique was selected to allow for gradual onset of anesthesia and tight hemodynamic control. The patient was managed in a multidisciplinary setting involving anesthesiology, cardiology, obstetrics, and intensive care. Intraoperative and postoperative periods were uneventful, with no signs of pulmonary edema or right ventricular failure. The patient was discharged in stable condition on postoperative day 7. This case highlights the critical importance of individualized anesthetic planning and collaborative multidisciplinary care in the management of high-risk obstetric patients with PPCM and PAH. Early diagnosis, careful monitoring, and tailored interventions are key to optimizing maternal and neonatal outcomes in such complex scenarios.

围产期心肌病(PPCM)合并肺动脉高压(PAH)是一种罕见的高风险疾病,对麻醉和产科造成了重大挑战。本病例报告通过描述一个伴有严重心功能障碍和PAH的产妇的成功麻醉管理,对有限的文献做出了贡献,强调了多学科方法的重要性。一位30岁的孕妇,新诊断为病因不明的扩张型心肌病和PAH,接受选择性剖宫产。诊断建立在妊娠中期,在休息时出现呼吸困难的症状。经胸超声心动图显示严重的左心室收缩功能障碍和肺动脉压升高。选择脊髓-硬膜外联合技术,以允许逐渐开始麻醉和严密的血流动力学控制。患者在多学科环境下进行管理,包括麻醉学,心脏病学,产科和重症监护。术中和术后均无异常,无肺水肿或右心室衰竭迹象。患者术后第7天出院,病情稳定。本病例强调了个体化麻醉计划和多学科合作护理在PPCM和PAH高危产科患者管理中的重要性。在这种复杂的情况下,早期诊断、仔细监测和有针对性的干预措施是优化孕产妇和新生儿结局的关键。
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引用次数: 0
The Editor's Desk: Evidenced-Based Practice and Quality Improvement Projects Can Improve Anesthesia Outcomes. 编者按:循证实践和质量改进项目可以改善麻醉结果。
Q3 Medicine Pub Date : 2025-08-01
Charles A Griffis, Cormac O'Sullivan, Edwin N Aroke
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引用次数: 0
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