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Quantitative Neuromuscular Monitoring Permits Early Diagnosis of Abnormal Butyrylcholinestrase: Two Case Studies Demonstrating Prevention of Awareness from Premature Awakening. 定量神经肌肉监测可及早诊断丁酰胆硷酯酶异常:两例研究证明可预防过早觉醒。
Q3 Medicine Pub Date : 2024-04-01
Erica M Harris, Emily M Funk, Daniel Plezia, Judson Elliott, Ryland Elliott, Jessica Szydlowski Pitman, Stuart A Grant

Administration of succinylcholine to patients with a variant in the butyrylcholinesterase (BChE) gene increases the risk of anesthesia emergence prior to recovery from neuromuscular blockade (NMB). Application of quantitative neuromuscular monitoring (NMM) can identify residual NMB. We present two patients with abnormal BChE gene variants. In the first case, quantitative monitoring was applied too late to prevent awareness, but allowed diagnosis and prevented admission to the intensive care unit. In the second case, monitoring was applied prior to NMB, which enabled early diagnosis and prevented premature awakening from anesthesia. These cases illustrate the importance of quantitative NMM, even in short cases and with short-acting depolarizing agents such as succinylcholine. The clinical implications of this report include a more consistent use of NMM to identify and manage patients with undiagnosed abnormal BChE and to prevent premature anesthesia emergence.

给丁酰胆碱酯酶(BChE)基因变异的患者注射琥珀胆碱会增加在神经肌肉阻滞(NMB)恢复前出现麻醉的风险。应用定量神经肌肉监测(NMM)可以识别残留的 NMB。我们介绍了两名 BChE 基因变异异常的患者。在第一个病例中,定量监测的应用为时已晚,无法阻止患者意识到这一点,但还是确诊了病情,避免了患者进入重症监护室。在第二个病例中,监测是在 NMB 之前进行的,因此可以及早诊断并防止过早从麻醉中苏醒。这些病例说明了定量 NMM 的重要性,即使在短病例和使用琥珀胆碱等短效去极化药物时也是如此。本报告的临床意义包括更一致地使用 NMM 来识别和管理 BChE 异常未确诊的患者,并防止麻醉过早苏醒。
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引用次数: 0
A New Distal Pharyngeal Airway Device Associated with a Reduced Need for Chin-Lift and Jaw-Thrust Maneuvers in Sedated Patients. 新型远端咽部气道装置可减少镇静患者的抬下巴和推颌动作。
Q3 Medicine Pub Date : 2024-04-01
Carol Daniel, Monika Feeney, Leah Gordon

Oropharyngeal airways (OPA) or nasopharyngeal airways (NPA) sometimes require chin-lift or jaw-thrust (CLJT) maneuvers to relieve airway obstruction which creates the burden of continuous hands-on care by the anesthesia provider. A new distal pharyngeal airway device (DPA) was used on 63 successive ambulatory surgery patients to assess the frequency of patients requiring manual CLJT maneuvers to prevent airway obstruction. Results were then compared with a contemporaneous group of patients who had used OPA or NPA devices for similar procedures. Patients using the DPA had a 38.5% lower rate of CLJT maneuvers compared with the combined OPA/NPA groups (22.2% of 63 vs. 60.7% of 163, P ≤ .001). Moreover, the results for the DPA group were close to those of the natural airway group (22.2% of 62 vs. 24.8% of 233, P = .66) Results were similar for a sub-set of the above groups who required deep sedation or deep extubation. CLJT maneuvers were common in this ambulatory surgery setting. The new DPA device was associated with a reduced need for such manual maneuvers when compared with similar patients who received OPA or NPA devices and is comparable with the rate for natural airways.

口咽通气道(OPA)或鼻咽通气道(NPA)有时需要下巴抬高或下颌推举(CLJT)操作来缓解气道阻塞,这给麻醉提供者带来了持续动手护理的负担。我们对 63 名连续接受非卧床手术的患者使用了新型远端咽通气设备 (DPA),以评估患者需要手动 CLJT 操作以防止气道阻塞的频率。然后将结果与同时使用 OPA 或 NPA 装置进行类似手术的一组患者进行比较。与 OPA/NPA 组相比,使用 DPA 的患者的 CLJT 操作率降低了 38.5%(63 例中的 22.2% 对 163 例中的 60.7%,P ≤ .001)。此外,DPA 组的结果与自然气道组的结果接近(62 例中的 22.2% 对 233 例中的 24.8%,P = .66)。 上述组别中需要深度镇静或深度拔管的子组别结果类似。CLJT操作在门诊手术环境中很常见。与接受 OPA 或 NPA 设备的类似患者相比,新型 DPA 设备减少了此类手动操作的需求,与自然气道的比率相当。
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引用次数: 0
Challenges for Nurse Anesthetists Reentering Practice Following Substance Use Disorder Treatment. 麻醉师在药物使用障碍治疗后重新执业面临的挑战。
Q3 Medicine Pub Date : 2024-04-01
T'Anya Carter, Nancy Wingo, Susan McMullan, Gwen Childs, Bernadette Roche, Lisa J Merlo, Karen Heaton

Substance use disorder (SUD) is a persistent, relapsing condition that is present in approximately 10% of anesthesia providers, who, compared with other healthcare providers, face a greater risk of developing an SUD by virtue of constant access to medications. The ability of certified registered nurse anesthesiologists (CRNAs) to obtain or maintain employment after treatment for SUD treatment is not well documented. The purpose of this qualitative study was to explore challenges encountered by CRNAs in recovery as they attempt to reenter practice following SUD treatment. The phenomenon was explored through multiple-case study, using qualitative semistructured interviews with participants in four cases: CRNAs in recovery, CRNA colleagues, CRNA employers, and professional health program employees. Thirty-six participants conveyed their perspectives about challenges that CRNAs in recovery face upon reentry into practice following SUD treatment. The Worker Well-Being conceptual model was used to guide this study. The study revealed that more SUD education is a key facilitator for reentry, risk of relapse was a major concern, and stigma was the most significant barrier for CRNAs in recovery. Stigma persists as a considerable barrier in many facets of SUD, contributing to an increase in shame associated with having the disease.

药物使用障碍(SUD)是一种持续性、复发性疾病,约有 10% 的麻醉服务提供者患有这种疾病,与其他医疗服务提供者相比,他们因经常接触药物而面临患上药物使用障碍的更大风险。关于注册麻醉师(CRNA)在接受 SUD 治疗后获得或维持工作的能力,目前尚无充分的记录。本定性研究旨在探讨处于康复期的注册麻醉师在接受药物依赖治疗后试图重新执业时所遇到的挑战。本研究通过多案例研究,对四个案例的参与者进行了半结构化定性访谈:这四个案例分别是:康复中的 CRNA、CRNA 同事、CRNA 雇主以及专业健康项目员工。36 名参与者表达了他们对康复中的 CRNA 在接受 SUD 治疗后重新执业时所面临的挑战的看法。本研究采用了 "工作者幸福 "概念模型作为指导。研究显示,更多的 SUD 教育是重新执业的关键促进因素,复发风险是一个主要问题,而污名化是康复中的注册护士面临的最大障碍。在 SUD 的许多方面,污名化始终是一个相当大的障碍,导致与患病相关的羞耻感增加。
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引用次数: 0
A Novel Mechanistic Model for Future Research in the Elements of the ERAS Program in Patients With Sickle Cell Disease. 镰状细胞病患者 ERAS 计划要素未来研究的新机制模型。
Q3 Medicine Pub Date : 2024-04-01
Marcy Purnell, Michong Rayborn

Enhanced recovery after surgery (ERAS) is a patient-centered, evidence-based, multidisciplinary team-developed approach to a surgical stress response that is implemented to optimize physiological function and facilitate recovery for the best possible outcomes from surgery. Although there are currently well-known published guidelines for the perioperative management of patients with sickle cell disease, there are currently no specific and evidencebased ERAS protocols that address the needs of these patients. A novel mechanistic model has recently been found that could change ERAS protocols for patients with sickle cell disease with regard to a current preoperative carbohydrate loading drink recommendation, nutrition and intravenous fluid management. ERAS has great benefits for most patient populations, but emerging research suggests that patients with sickle cell disease may process and respond differently to varying concentrations of serum glucose and serum cations (hyperglycemia and hypertonic states). This adverse response involves actin, a cytoskeletal protein, in the red blood cell and how increased hemoglobin glycosylation may lead to a malfunction in this protein and a transition to vaso-occlusive crises in patients with sickle cell disease. Further research is warranted with this new mechanistic model to develop more meticulous and customized perioperative management plans to address risk mitigation in patients with sickle cell disease.

加强术后恢复(ERAS)是一种以患者为中心、以证据为基础、由多学科团队开发的手术应激反应方法,其实施目的是优化生理功能,促进术后恢复,以尽可能获得最佳手术效果。虽然目前已有众所周知的镰状细胞病患者围手术期管理指南,但目前还没有具体的循证 ERAS 方案来满足这些患者的需求。最近发现了一种新的机理模型,可以改变镰状细胞病患者的 ERAS 方案,即目前的术前碳水化合物负荷饮料建议、营养和静脉输液管理。ERAS 对大多数患者都有很大益处,但新的研究表明,镰状细胞病患者可能会对不同浓度的血清葡萄糖和血清阳离子(高血糖和高渗状态)产生不同的处理和反应。这种不良反应涉及红细胞中的肌动蛋白(一种细胞骨架蛋白),以及血红蛋白糖基化的增加如何导致这种蛋白的功能失调和镰状细胞病患者血管闭塞危象的转变。有必要利用这一新的机理模型开展进一步研究,以制定更细致、更个性化的围手术期管理计划,降低镰状细胞病患者的风险。
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引用次数: 0
Anesthesia Medication Safety in Relation to Pharmacopeia Medication Use Best Practice Initiatives. 麻醉用药安全与药典用药最佳实践倡议的关系。
Q3 Medicine Pub Date : 2024-04-01
David B Koontz

Improvement to anesthesia medication safety is a useful and worthwhile area of research. Anesthesia is one of the few healthcare professions to have immediate access to compounding and label high-hazard medications at the bedside. There is a need to assess the perceptions of anesthesia medication safety and this relationship with pharmacopeia's updated recommendations for anesthesia to improve medication safety and prevent adverse drug events. Certified registered nurse anesthetist (CRNA) perceptions of medication safety climate in Florida were measured utilizing a validated Likert-scale that merged the Attitudes Questionnaire themes of teamwork, climate, safety climate, job satisfaction, stress recognition, perceptions of management, and working. The Agency for Healthcare Research and Quality Hospital Survey on Patient Safety Culture themes utilized were organizational learning, error communication, and support for patient safety. The overall email invitations delivered 5,890, 524 participants voluntarily started, and 401 completed the questionnaire resulting in a 77% completion rate. The overall response rate was 8.896% and 6.8% overall completion rate. The findings demonstrate a correlation between themes related to supportive organizational learning, stress reduction, positive changes, and creating anesthesia medication quality improvements. CRNAs' openness in adopting new pharmacopeia best practice recommendations can improve anesthesia medication safety delivery. The survey indicated clinical noteworthiness that supports the importance of additional examination of frontline providers' perceptions regarding anesthesia medication safety, buy-in, and adoption of updated pharmacopeia recommendations.

提高麻醉用药安全是一个有用且值得研究的领域。麻醉是少数几个可以在床边立即使用复方制剂和标记高危药物的医疗行业之一。有必要评估对麻醉用药安全的看法以及这种看法与药典对麻醉的最新建议之间的关系,以提高用药安全并预防药物不良事件的发生。佛罗里达州的注册麻醉师(CRNA)对用药安全氛围的感知采用了经过验证的李克特量表进行测量,该量表将团队合作、氛围、安全氛围、工作满意度、压力识别、管理感知和工作态度问卷的主题合并在一起。医疗保健研究与质量机构医院患者安全文化调查的主题是组织学习、错误沟通和对患者安全的支持。总计发出了 5,890 份电子邮件邀请,524 人自愿开始填写,401 人完成了问卷,完成率为 77%。总回复率为 8.896%,总完成率为 6.8%。研究结果表明,与支持性组织学习、减轻压力、积极变化和提高麻醉用药质量相关的主题之间存在关联。临床麻醉师对采用新药典最佳实践建议的开放态度可以改善麻醉用药安全。调查显示临床值得关注,这支持了进一步检查一线医疗人员对麻醉用药安全、接受和采纳最新药典建议的看法的重要性。
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引用次数: 0
Implementation of a Spaced Learning Program for Educating CRNAs on a Scalpel-Bougie Cricothyrotomy Procedure for Emergency Front of Neck Access. 实施间隔学习计划,对急诊前颈入路手术中的手术刀-鼻饲环甲膜切开术的急诊麻醉师进行教育。
Q3 Medicine Pub Date : 2024-04-01
Antoinette T Padula, Joy Elwell, Maria Madonick, Michael Wilhelm, Don Boyd

Certified registered nurse anesthetists (CRNAs) who are responsible for airway management, may lack adequate continuing education for emergency front of neck access (EFONA), an advanced skill necessary in situations when a patient cannot be intubated and cannot be oxygenated (CICO). The purpose of this study was to improve CRNA knowledge and confidence when performing a scalpel-bougie cricothyrotomy for EFONA in a CICO event through the implementation of a spaced learning intervention. Thirteen CRNAs at a 160-bed community hospital participated in a 3-week educational intervention. Week 1: online preintervention survey followed by an educational video. Week 2: video review and skills component practiced on a cricothyrotomy trainer. Week 3: skills component practiced on a cricothyrotomy trainer followed by postintervention survey. This was a single-arm study and Wilcoxon sign ranked tests and a paired t-test were utilized to monitor for change in CRNA knowledge, confidence, and skill in performing EFONA. Implementation of a 3-week spaced learning program for educating CRNAs to perform a scalpel-bougie cricothyrotomy significantly increased CRNA knowledge, confidence, and skill when performing EFONA. Utilizing a spaced learning program may therefore improve provider skills, resulting in optimized patient care during a CICO event, leading to improved patient safety and outcomes.

负责气道管理的注册麻醉师(CRNA)可能缺乏足够的紧急颈前通路(EFONA)继续教育,而这是在患者无法插管和无法吸氧(CICO)的情况下所必需的高级技能。本研究旨在通过实施间隔学习干预措施,提高注册护士在 CICO 事件中为 EFONA 实施手术刀-鼻饲环甲膜切开术时的知识和信心。一家拥有 160 张病床的社区医院的 13 名急诊科护士参加了为期 3 周的教育干预。第 1 周:在线干预前调查,随后观看教育视频。第 2 周:视频回顾和环甲膜切开术训练器技能练习。第 3 周:在环甲膜切开术训练器上练习技能部分,然后进行干预后调查。这是一项单臂研究,采用 Wilcoxon 符号排序检验和配对 t 检验来监测 CRNA 在执行 EFONA 时的知识、信心和技能的变化。通过实施为期 3 周的间隔学习计划,对急诊科护士进行手术刀-口腔插管环甲膜切开术的教育,显著提高了急诊科护士在实施 EFONA 时的知识、信心和技能。因此,利用间隔学习计划可以提高医护人员的技能,从而在 CICO 事件中优化患者护理,提高患者安全和治疗效果。
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引用次数: 0
A Mixed-Methods Exploration of Competencies and Professional Development Needs Among Chief Certified Registered Nurse Anesthetists. 对首席注册麻醉师能力和职业发展需求的混合方法探索。
Q3 Medicine Pub Date : 2024-04-01
Austin L Cole, Virginia C Simmons, Barbara S Turner, Robert Whitehurst, Denise H Tola

This project sought to explore the experiences, self-perceived preparation, professional development needs, and preferred learning methods of certified registered nurse anesthetists (CRNAs) in a management role. A sample of 10 current chief CRNAs responded to a demographics survey and participated in one-on-one interviews using a 14-question, semi-structured interview framework modified from a previous study. Interview responses were deidentified and qualitatively analyzed for common themes by two content experts and one qualitative analysis expert. Results suggest that CRNAs entering the management field feel somewhat unprepared to perform the administrative tasks associated with their role. Qualitative analysis of interview responses elicited multiple key themes including interpersonal communication and handling crucial conversations, time and organizational management skills, team building and motivation, and financial management skills. Themes related to preferred learning methods of chief CRNAs included mentorship, peer networking, and experiential learning to obtain the required knowledge and skills for the role. The authors recommend incorporating each of the identified themes to guide development of CRNA management-specific educational programs. Establishing such a program will serve to better prepare aspiring CRNA managers and further develop the knowledge and skillset of current chief CRNAs.

本项目旨在探讨担任管理职务的注册麻醉师(CRNA)的经验、自我认知的准备情况、专业发展需求以及偏好的学习方法。10 名现任注册麻醉师主管对一份人口统计学调查做出了答复,并参与了一对一访谈,访谈采用了根据之前研究修改过的 14 个问题的半结构化访谈框架。两位内容专家和一位定性分析专家对访谈回答进行了去身份化处理,并对共同主题进行了定性分析。结果表明,进入管理领域的急诊麻醉师在执行与其角色相关的行政任务时感到有些措手不及。对访谈回答的定性分析引出了多个关键主题,包括人际沟通和处理关键对话、时间和组织管理技能、团队建设和激励以及财务管理技能。首席注册护士首选的学习方法包括导师指导、同行交流和体验式学习,以获得角色所需的知识和技能。作者建议将所确定的每个主题纳入指导开发 CRNA 管理专用教育计划的过程中。建立这样的计划将有助于更好地培养有抱负的 CRNA 管理人员,并进一步发展现任首席 CRNA 的知识和技能。
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引用次数: 0
Imagining in Time: The Legacy of Olive Berger (1898-1981). 时间中的想象:奥利弗-伯杰(1898-1981 年)的遗产。
Q3 Medicine Pub Date : 2024-04-01
Andrew R Benson, Catherine Horvath, Marjorie Everson, Bruce Schoneboom

Olive Berger was a true nurse anesthesia pioneer for our profession. She dedicated her life to the advancement of nurse anesthesia through her leadership, advocacy, scholarly writing, clinical achievements and innovation. She blazed the trail by forming and establishing education requirements for nurse anesthesia programs, established a state nurse anesthesia organization, and led the American Association of Nurse Anesthetists as its 14th president in 1958. She was the Chief Certified Registered Nurse Anesthetist and Program Director at the Johns Hopkins Hospital and is best known for her collaboration with surgeons Dr. Alfred Blalock and Dr. Helen Taussig, providing anesthesia care during the groundbreaking repair of tetralogy of Fallot on infants.

奥利弗-伯杰是我们行业真正的麻醉护士先驱。她通过领导、宣传、学术著作、临床成就和创新,将毕生精力奉献给了麻醉护士事业的发展。她开辟了一条道路,形成并确立了麻醉护士课程的教育要求,建立了州麻醉护士组织,并于 1958 年作为第 14 任主席领导了美国麻醉护士协会。她曾担任约翰霍普金斯医院的首席注册麻醉护士和项目主任,最著名的是她与外科医生阿尔弗雷德-布洛克(Alfred Blalock)博士和海伦-陶西格(Helen Taussig)博士合作,在开创性的法洛氏四联症婴儿修复手术中提供麻醉护理。
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引用次数: 0
Educational Costs Expended and Career Incomes in Advanced Healthcare Professions. 高级医疗保健专业的教育成本支出和职业收入。
Q3 Medicine Pub Date : 2024-02-01
Melissa M Brown, Gary C Brown, Meg R Smith

The financial desirability of dollar/time investments in postbaccalaureate healthcare professional education is needed. We therefore compared postbaccalaureate educational costs and career earnings for nurse anesthetists, eight other advanced degree, nonphysician professions, and 14 physician specialties with internal rate of return (IRR) and net present value (NPV) analysis. The IRR and NPV integrated educational costs (tuition, finance charges, lost salary opportunity costs), and career earnings using U.S. Bureau of Labor and Medscape 2022 Physician Compensation Report data. Costs were discounted to 2022 U.S. real dollars using the 3.97% 50-year, U.S. average inflation rate. Annual IRRs for educational investment were 1) hospital CEOs = 48.8%; 2) managed care finance directors = 48.2%; 3) Doctors of Nurse Anesthesia Practice = 26.0%; 4) specialist physicians = 20.3%; 5) primary care physicians = 19.2%; 6) Doctors of Physical Therapy = 18.8%; 7) healthcare attorneys = 18.4%; 8) Doctors of Dental Surgery (dentists) = 18.1%; 9) Doctors of Pharmacy = 17.2%; and 10) Advanced Nurse Practitioners = 10.8%. Considering the educational money/time invested for career monetary returns, the financial desirability of nurse anesthetist and nonphysician, healthcare executive education exceeded that of physicians. Lifetime earnings for nurse anesthetists exceeded those of Doctors of Dental Surgery (Doctors of Dental Medicine), Doctors of Pharmacy, Doctors of Physical Therapy, managed care MBAs, biomedical engineers, healthcare attorneys, and Advanced Nurse Practitioners.

需要对学士后医疗保健专业教育的美元/时间投资的经济可取性进行研究。因此,我们通过内部收益率(IRR)和净现值(NPV)分析,比较了麻醉护士、其他八个高级学位、非医师专业和 14 个医师专业的学士后教育成本和职业收入。内部收益率和净现值综合了教育成本(学费、财务费用、工资机会成本损失)和职业收入,使用的是美国劳工局和 Medscape 2022 年医生薪酬报告数据。成本使用 3.97% 的 50 年美国平均通货膨胀率折算成 2022 年的实际美元。教育投资的年度内部收益率分别为:1)医院首席执行官 = 48.8%;2)管理式医疗财务总监 = 48.2%;3)麻醉护士执业医生 = 26.0%;4)专科医生 = 20.3%;5)初级保健医生 = 19.2%;6)理疗医师 = 18.8%;7)医疗保健律师 = 18.4%;8)牙科手术医师(牙医) = 18.1%;9)药剂师 = 17.2%;10)高级执业护士 = 10.8%。考虑到为获得职业货币回报而投入的教育资金/时间,麻醉护士和非医师医疗保健管理人员教育的经济可取性超过了医师。麻醉护士的终生收入超过了牙科医学博士、药学博士、理疗学博士、管理型医疗 MBA、生物医学工程师、医疗保健律师和高级执业护士。
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引用次数: 0
Preliminary Investigation: Pilot Study of Program Directors' Perceptions of Wellness and Suicide Prevention for Student Registered Nurse Anesthetists. 初步调查:项目主任对注册麻醉师学生健康和自杀预防看法的试点研究。
Q3 Medicine Pub Date : 2024-02-01
Charles A Griffis, Elizabeth Bamgbose, Maria Van Pelt, Holli DeVon, Holly Wilhalme, Kristen Choi

The purpose of this pilot study was to investigate wellness and student suicidality in nurse anesthesia programs. Graduate students such as student registered nurse anesthetists (SRNAs) are at increased risk of suicide from environmental and educational stressors. Wellness interventions may help. An observational, anonymous online survey of all program directors (PDs) was conducted. Identical responses on a simultaneous pilot SRNA study were compared. Quantitative data were analyzed using Wilcoxon rank sum and Fisher's exact tests. Three PDs reported student suicides. Anxiety, depression, and emotional lability were warning signs. Student and PD responses to wellness program assessments were varied, with PD responses more positive and students more negative. PDs were as stressed as students and struggled to meet their own wellness needs. Most PDs reported no or insufficient training in suicide risk and prevention. Suggestions for improving wellness initiatives included to improve and standardize activities and make initiatives more accessible and seek innovative solutions to fit more content into an overcrowded curriculum. PDs and SRNAs need suicide prevention training and improved wellness efforts at local and national levels. Approaches are needed to counter stigma and reluctance to discuss mental health challenges. Suicide is multidimensional, but with proactive awareness, it may be preventable.

这项试点研究旨在调查麻醉护士课程中的健康与学生自杀倾向。由于环境和教育方面的压力,注册麻醉护士(SRNA)等研究生的自杀风险越来越高。健康干预措施可能会有所帮助。我们对所有项目主任(PDs)进行了匿名在线观察调查。比较了同时进行的 SRNA 试点研究中的相同回答。采用 Wilcoxon 秩和检验和费雪精确检验对定量数据进行了分析。三位 PD 报告了学生自杀事件。焦虑、抑郁和情绪不稳定是预警信号。学生和助教对健康计划评估的反应各不相同,助教的反应更积极,学生的反应更消极。专业教师和学生一样感到压力,并努力满足自己的健康需求。大多数专业教师表示没有接受过自杀风险和预防方面的培训或培训不足。关于改进健康计划的建议包括:改进活动并使之标准化,使活动更易于开展,以及寻求创新的解决方案,在过于拥挤的课程中加入更多的内容。PD 和 SRNA 需要接受自杀预防培训,并在地方和国家层面改进健康工作。需要采取各种方法来消除耻辱感和不愿讨论心理健康挑战的情绪。自杀是一个多层面的问题,但如果能积极主动地提高认识,自杀是可以预防的。
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引用次数: 0
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