Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa2420
A. G. Algera, F. Simonis, C. Pierrakos, M. Botta, Claudio Zimatore, L. Pisani, P. Tuinman, L. Bos, W. Lagrand, M. G. de Abreu, P. Pelosi, A. Neto, M. Schultz, T. Cherpanath, F. Paulus
{"title":"Effects of tidal volume and PEEP on myocardial performance in ICU patients without ARDS","authors":"A. G. Algera, F. Simonis, C. Pierrakos, M. Botta, Claudio Zimatore, L. Pisani, P. Tuinman, L. Bos, W. Lagrand, M. G. de Abreu, P. Pelosi, A. Neto, M. Schultz, T. Cherpanath, F. Paulus","doi":"10.1183/13993003.congress-2021.pa2420","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa2420","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90385497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa3781
P. Kapisyzi, E. Tashi, Eugerta Dilka, S. Telo, Alma Teferici, Esmeralda Nushi, Kloedina Bratja, Armela Cuko, Valentina Hima, L. Hoxha, Serxho Golgota, Emira Osja, Franc Rrumbullaku, Marsel Broqi, Edi Vakeflliu, Erjon Sula, S. Bala
{"title":"Late Breaking Abstract - The mortality predicting factors at admission and during hospitalisation of pateints with SARS COV2","authors":"P. Kapisyzi, E. Tashi, Eugerta Dilka, S. Telo, Alma Teferici, Esmeralda Nushi, Kloedina Bratja, Armela Cuko, Valentina Hima, L. Hoxha, Serxho Golgota, Emira Osja, Franc Rrumbullaku, Marsel Broqi, Edi Vakeflliu, Erjon Sula, S. Bala","doi":"10.1183/13993003.congress-2021.pa3781","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3781","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86792408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa2429
S. Baumgartner, M. Lubnow, M. Malfertheiner, A. Philipp, M. Foltan, D. Lunz, T. Müller, C. Fisser
{"title":"Major bleeding and thromboembolic events in veno-venous ECMO-patients with isolated respiratory failure. A retrospective analysis","authors":"S. Baumgartner, M. Lubnow, M. Malfertheiner, A. Philipp, M. Foltan, D. Lunz, T. Müller, C. Fisser","doi":"10.1183/13993003.congress-2021.pa2429","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa2429","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87174917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa905
M. Smit, L. Beenen, C. Valk, M. D. de Boer, M. Scheerder, J. Annema, F. Paulus, J. Horn, A. Vlaar, F. Kooij, M. Hollmann, M. Schultz, L. Bos
{"title":"Assessment of lung re-aeration at two levels of PEEP in patients with early and late COVID-19 related ARDS – a retrospective analysis","authors":"M. Smit, L. Beenen, C. Valk, M. D. de Boer, M. Scheerder, J. Annema, F. Paulus, J. Horn, A. Vlaar, F. Kooij, M. Hollmann, M. Schultz, L. Bos","doi":"10.1183/13993003.congress-2021.pa905","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa905","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87533685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa3765
N. Alekhmimi, J. Popp, M. Zourob
{"title":"MMP2 probe based on in vivo imaging technique for tracking ALI/ARDS in mice","authors":"N. Alekhmimi, J. Popp, M. Zourob","doi":"10.1183/13993003.congress-2021.pa3765","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3765","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85414322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.oa4028
A. Agrawal, A. Garg, M. Gurjar, U. Ghoshal, P. Mishra, Akshay K Arya, Shreyas Gutte, G. Pandey
{"title":"Late Breaking Abstract - Cytomegalovirus reactivation in COVID-19 patients with Acute Respiratory Distress Syndrome","authors":"A. Agrawal, A. Garg, M. Gurjar, U. Ghoshal, P. Mishra, Akshay K Arya, Shreyas Gutte, G. Pandey","doi":"10.1183/13993003.congress-2021.oa4028","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa4028","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88608724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.oa4024
L. Hagens, A. Verschueren, A. Lammers, N. Heijnen, M. Smit, T. Nijsen, Inge Geven, M. Schultz, D. Bergmans, R. Schnabel, L. Bos
{"title":"Development and validation of a point of care breath test for octane detection","authors":"L. Hagens, A. Verschueren, A. Lammers, N. Heijnen, M. Smit, T. Nijsen, Inge Geven, M. Schultz, D. Bergmans, R. Schnabel, L. Bos","doi":"10.1183/13993003.congress-2021.oa4024","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa4024","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89423429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa3772
T. Katsuno, Manabu Suzuki, M. Hojo, J. Takasaki, H. Sugiyama
{"title":"Clinical experience with high-flow nasal cannula for COVID-19 patients in Japan","authors":"T. Katsuno, Manabu Suzuki, M. Hojo, J. Takasaki, H. Sugiyama","doi":"10.1183/13993003.congress-2021.pa3772","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3772","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89572099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-15DOI: 10.22541/AU.161339396.63905015/V1
B. Kerget, F. Kerget, A. Aksakal, S. Askin, E. Uçar, L. Sağlam
Objective: COVID-19 is one of the most important health problems concerning the last century and our knowledge of the disease is still limited. In our study, we aimed to compare serum-soluble urokinase plasminogen activator receptor (suPAR) and kidney injury molecule-1 (KIM-1) level with clinical course in COVID-19 patients. Methods: Our study included 102 patients over the age of 18 who were diagnosed with Covid-19 between September 2020 and December 2020 by taking nasopharyngeal swap and using real time PCR method and 30 volunteer medical personnel over the age of 18 who were PCR negative after the nasopharyngeal swap. KİM-1 and suPAR were measured by enzyme-linked immunosorbent assay. Results: NLR, LDH, prothrombin time, CRP, PaO2/FiO2, D-Dimer, ferritin and fibrinogen levels, which have been mentioned in previous studies to be of prognostic importance for COVID-19, were observed to be higher in the severely ill group (p=0,001, 0,001, 0,05, 0,001, 0,001, 0,005, 0,001, 0,001 respectively). suPAR and KIM-1 levels were statistically significantly higher in patient groups compared to the control group (p=0.001 for all). While suPAR level was statistically significantly lower in severe patients compared to moderate patients (p=0.034), KIM-1 level was observed to be higher in severe patients (p=0.001). Conclusion: The increased level of KIM-1 in severe patients, which is thought to play an important role in the endocytosis of SARS-CoV-2 to the cell, may have an important place for the therapeutic target in the future. SuPAR can be considered to play an important role especially in the defense mechanism and fibrinolysis and its decreased level in severe patients may be associated with poor prognosis in the early period. However, extensive studies are needed to reach a definitive opinion about suPAR.
{"title":"Evaluation of the relationship between KIM-1 and suPAR level in COVID-19 patients and a different perspective on suPAR","authors":"B. Kerget, F. Kerget, A. Aksakal, S. Askin, E. Uçar, L. Sağlam","doi":"10.22541/AU.161339396.63905015/V1","DOIUrl":"https://doi.org/10.22541/AU.161339396.63905015/V1","url":null,"abstract":"Objective: COVID-19 is one of the most important health problems\u0000concerning the last century and our knowledge of the disease is still\u0000limited. In our study, we aimed to compare serum-soluble urokinase\u0000plasminogen activator receptor (suPAR) and kidney injury molecule-1\u0000(KIM-1) level with clinical course in COVID-19 patients. Methods: Our\u0000study included 102 patients over the age of 18 who were diagnosed with\u0000Covid-19 between September 2020 and December 2020 by taking\u0000nasopharyngeal swap and using real time PCR method and 30 volunteer\u0000medical personnel over the age of 18 who were PCR negative after the\u0000nasopharyngeal swap. KİM-1 and suPAR were measured by enzyme-linked\u0000immunosorbent assay. Results: NLR, LDH, prothrombin time, CRP,\u0000PaO2/FiO2, D-Dimer, ferritin and fibrinogen levels, which have been\u0000mentioned in previous studies to be of prognostic importance for\u0000COVID-19, were observed to be higher in the severely ill group (p=0,001,\u00000,001, 0,05, 0,001, 0,001, 0,005, 0,001, 0,001 respectively). suPAR and\u0000KIM-1 levels were statistically significantly higher in patient groups\u0000compared to the control group (p=0.001 for all). While suPAR level was\u0000statistically significantly lower in severe patients compared to\u0000moderate patients (p=0.034), KIM-1 level was observed to be higher in\u0000severe patients (p=0.001). Conclusion: The increased level of KIM-1 in\u0000severe patients, which is thought to play an important role in the\u0000endocytosis of SARS-CoV-2 to the cell, may have an important place for\u0000the therapeutic target in the future. SuPAR can be considered to play an\u0000important role especially in the defense mechanism and fibrinolysis and\u0000its decreased level in severe patients may be associated with poor\u0000prognosis in the early period. However, extensive studies are needed to\u0000reach a definitive opinion about suPAR.","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78529687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-07DOI: 10.1183/13993003.congress-2020.2012
M. Lee, Kwangha Lee
{"title":"SOFA (Sequential Organ Failure Assessment) Score As A Predictor Of Moartality In Ventilated Patients With Multi-drug Resistant Bacteremia","authors":"M. Lee, Kwangha Lee","doi":"10.1183/13993003.congress-2020.2012","DOIUrl":"https://doi.org/10.1183/13993003.congress-2020.2012","url":null,"abstract":"","PeriodicalId":7201,"journal":{"name":"Acute critical care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77908727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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