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Hospital waterbirth for low-risk birthing people: findings of a randomized controlled trial 低风险分娩人群的医院水分娩:一项随机对照试验的结果
Pub Date : 2025-08-14 DOI: 10.1016/j.xagr.2025.100558
Emily Malloy PhD, CNM , Jessica J.F. Kram MPH , James O. Adefisoye PhD , Marie Forgie DO , Diana Kleber RN , MaryAnne Scherer CNM , Anna Anklam CNM , Natasha Hernandez MD , Lisa Hanson PhD, CNM
<div><h3>Background</h3><div>Waterbirth is the act of giving birth submerged in a tub of warm water, with the baby born underwater. Support for widespread adoption of waterbirth in the United States (US) has been limited by predominantly retrospective study designs, the underutilization of interdisciplinary citations, and disagreement between professional organizations. No randomized controlled trials of waterbirth have been conducted in the US.</div></div><div><h3>Objective</h3><div>The purpose of this randomized controlled trial was to compare pain management, maternal and neonatal outcomes, and maternal satisfaction between low-risk water and land group study participants.</div></div><div><h3>Study Design</h3><div>Low-risk pregnant adults were offered study participation between 25 to 34 weeks of gestation during routine prenatal care. Participants who met the inclusion criteria were consented, enrolled, and randomly assigned to waterbirth or land birth in a 2:1 unblinded fashion, to achieve a sample size of n=120 (80 waterbirth: 40 land birth). The sample size was adjusted for attrition and increased to n=186 (124 waterbirth: 62 land birth) based on an interim analysis. Participants in both arms were excluded if they developed intrapartum risk factors prior to delivery using a modified intention-to-treat model. Study participants received routine intrapartum care, including all available pain relief options. Only those assigned to the waterbirth group were given the option of giving birth in water. Prior to discharge, participants completed <em>The US Birth Satisfaction Scale Revised</em>. The primary study outcome was the use of any intravenous narcotics and/or epidural anesthesia. Secondary outcomes included predetermined composite maternal and neonatal outcomes and overall birth satisfaction. Using a modified intention-to-treat approach, outcomes were analyzed using Chi-square, Fisher’s Exact, or Wilcoxon-Mann-Whitney test as appropriate. Relative risks (RR) were computed where applicable.</div></div><div><h3>Results</h3><div>From January 2022 to December 2023, 186 participants were enrolled (n=124 waterbirth, n=62 land birth). Following enrollment, 106 participants (n=74 waterbirth, and n=32 land birth) remained eligible for the study. Attrition was 39%. Compared to the land birth group, waterbirth participants were significantly less likely to use intravenous narcotics [RR: 0.36 (95% confidence interval [CI], 0.17−0.75), <em>P<</em>.01] and epidural analgesia [RR: 0.38 (95% CI, 0.24−0.58), <em>P<</em>.01] and had shorter average first stage labor duration [median difference -2.00 hours (95% CI, -3.00 to 1.00), <em>P</em>=.43]. One cord avulsion occurred in the waterbirth group. Additional maternal and neonatal outcomes were not significantly different between groups. Waterbirth participants experienced higher overall birth satisfaction [median difference 3.50 (95% CI, 1.00-5.00), <em>P</em>=.01].</div></div><div><h3>Conclusion</h3>
水中分娩是指在一盆温水中分娩,婴儿在水下出生。在美国广泛采用水分娩的支持受到主要是回顾性研究设计、跨学科引用的利用不足以及专业组织之间的分歧的限制。在美国还没有进行过水中分娩的随机对照试验。目的:本随机对照试验的目的是比较低风险水组和陆地组研究参与者的疼痛管理、孕产妇和新生儿结局以及孕产妇满意度。研究设计:在常规产前护理期间,为妊娠25至34周的低风险孕妇提供研究参与。符合纳入标准的参与者被同意、登记,并以2:1的无盲方式随机分配到水中分娩或陆地分娩,以实现n=120的样本量(80个水中分娩:40个陆地分娩)。根据中期分析调整样本量,使样本量增加到186例(124例水中出生:62例陆地出生)。使用改良的意向治疗模型,如果两组参与者在分娩前出现产时危险因素,则将其排除在外。研究参与者接受了常规的分娩时护理,包括所有可用的疼痛缓解方案。只有那些被分配到水中分娩组的人可以选择在水中分娩。出院前,参与者完成了美国出生满意度量表修订。主要研究结果是静脉麻醉和/或硬膜外麻醉的使用。次要结局包括预先确定的产妇和新生儿综合结局和总体分娩满意度。采用改良的意向治疗方法,采用卡方检验、Fisher’s Exact检验或Wilcoxon-Mann-Whitney检验对结果进行分析。在适用的情况下计算相对风险(RR)。结果从2022年1月至2023年12月,共纳入186名参与者,其中水中出生124人,陆地出生62人。入组后,106名参与者(74名在水中出生,32名在陆地出生)仍符合研究条件。流失率为39%。与陆地分娩组相比,水中分娩组使用静脉麻醉药[RR: 0.36(95%可信区间[CI], 0.17 - 0.75), P<; 0.01]和硬膜外镇痛的可能性显著降低[RR: 0.38 (95% CI, 0.24 - 0.58), P< 0.01],平均第一产程较短[中位差-2.00小时(95% CI, -3.00至1.00),P=.43]。水中分娩组发生1例脐带撕脱。其他的产妇和新生儿结局在两组之间没有显著差异。水中分娩的参与者总体分娩满意度较高[中位数差异3.50 (95% CI, 1.00-5.00), P= 0.01]。结论越来越多的证据表明,水中分娩减少了静脉镇痛和麻醉的使用,提高了产妇的满意度。我们的研究结果为医院为低风险分娩人群提供水中分娩作为缓解疼痛的选择提供了支持。
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引用次数: 0
Monkeypox virus infection in a 23-year-old woman with a genital rash and global skin lesions: evidence for spouse-to-spouse transmission 出现生殖器皮疹和全身皮肤病变的23岁妇女猴痘病毒感染:配偶间传播的证据
Pub Date : 2025-08-14 DOI: 10.1016/j.xagr.2025.100550
Wen-Shuang Li MSc , Rong-Jing Dong PhD , Shui-Tao Yi MSc , Ru-Qin Zhang BSc , Rui-Xia Chen MSc , Yan-Jie Ning MSc , Dian-Jiang Xiao BSc
We report one case in China of a couple simultaneously infected with the monkeypox. Both spouses developed genital skin lesions successively and the female partner had widespread skin lesions all over her body, while the male partner is HIV-positive, had a history of homosexual behavior before the onset of symptoms.
我们报告一例在中国的一对夫妇同时感染猴痘。配偶双方均先后出现生殖器皮肤病变,女性伴侣全身广泛皮损,男性伴侣hiv阳性,发病前有同性恋行为史。
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引用次数: 0
A prospective study to correlate the cervical length by transvaginal ultrasound with preterm labor and perinatal outcomes 经阴道超声检查宫颈长度与早产及围产期结局的前瞻性研究
Pub Date : 2025-08-14 DOI: 10.1016/j.xagr.2025.100561
Nina Mahale MD , Devangi Panchal MS , Ajit Mahale MDRD , Sonali Ullal MDRD , Merwyn Fernandes DMRD, DNB, FRCR , Sonali Prabhu MDRD

BACKGROUND

This study aimed to investigate the role of transvaginal ultrasound as a screening tool to assess cervical length and improve perinatal outcomes to prevent preterm labor through appropriate interventions.

OBJECTIVE

This study aimed to determine the mean cervical length at 11 to 14 and 18 to 22 weeks of gestation and to estimate the rate of cervical length shortening and its correlation with birth outcomes.

STUDY DESIGN

This prospective study was conducted at Lady Goschen Hospital and KMC Hospital, Attavar, both of which are affiliated with Manipal Academy of Higher Education. This study included 93 pregnant women who came for antenatal care at Lady Goschen Hospital and KMC Hospital, Attavar, from December 2022 to August 2024. All participants provided consent to participate in the study. The formula is a follows: n = Zα2 (Sn)(1-Sn) / L2 × p, where Zα = 1.96 at a 95% confidence level, Sn = sensitivity, l = allowable error, and p = negative prevalence (Sn = 75% [reference article], L = 20% [80% power], and p = 50% (assumption) with 95% confidence interval and 80% power with respect to reference [prediction of preterm labor by cervical length]). Convenient sampling was performed. Data analysis was performed using descriptive statistics. Changes in follow-up were estimated using analysis of variance and the Bonferroni t test. Sensitivity, specificity, positive predictive value, and negative predictive value were estimated. Statistical analysis was performed using SPSS (version. 2.0; IBM, Armonk, New York). A P value of >.05 was considered statistically significant.

RESULTS

Cervical length measured using transvaginal ultrasound at 18 to 22 weeks of gestation was found to be more sensitive and to have better positive predictive value in predicting preterm labor than cervical length measured at 11 to 13 weeks of gestation. Cervical length between 18 and 22 weeks of gestation and the reduction of cervical length were found to be statistically significant in predicting preterm labor (P=.001).

CONCLUSION

Transvaginal ultrasound is a noninvasive and comparatively affordable modality for identifying women at risk of preterm labor. In addition, this technology could help identify women at risk of preterm labor, thereby reducing morbidity and mortality.
本研究旨在探讨经阴道超声作为一种评估宫颈长度的筛查工具的作用,并通过适当的干预措施改善围产期结局,以预防早产。目的本研究旨在测定妊娠11 ~ 14周和18 ~ 22周的平均宫颈长度,并估计宫颈长度缩短率及其与分娩结局的相关性。研究设计:本前瞻性研究在隶属于马尼帕尔高等教育学院的Lady Goschen医院和KMC医院进行。这项研究包括从2022年12月到2024年8月在阿塔瓦尔的Lady Goschen医院和KMC医院进行产前护理的93名孕妇。所有参与者都同意参加这项研究。公式是:n = Zα2 (Sn) (1-Sn) / L2 × p,在Zα = 1.96在95%置信水平,Sn = 敏感性,l = 容许误差,和p = 负患病率(Sn = 75%(参考文章),l = 20%(80%力量),和p = 50%(假设)和95%置信区间和80%力量对参考[预测早产的宫颈长度])。方便取样。数据分析采用描述性统计。使用方差分析和Bonferroni t检验估计随访的变化。评估敏感性、特异性、阳性预测值和阴性预测值。采用SPSS (version)进行统计分析。2.0;IBM,阿蒙克,纽约)。P值为>; 0.05认为有统计学意义。结果经阴道超声测定妊娠18 ~ 22周宫颈长度比妊娠11 ~ 13周宫颈长度对早产的预测更敏感,阳性预测值更高。妊娠18 ~ 22周宫颈长度和宫颈长度缩短对预测早产有统计学意义(P= 0.001)。结论经阴道超声是一种无创且价格相对低廉的方法,可用于鉴别有早产风险的妇女。此外,这项技术可以帮助识别有早产风险的妇女,从而降低发病率和死亡率。
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引用次数: 0
Relation between epidural analgesia and perinatal outcomes on Robson class 2a. Robson 2a类患者硬膜外镇痛与围产儿结局的关系。
Pub Date : 2025-08-06 eCollection Date: 2026-02-01 DOI: 10.1016/j.xagr.2025.100554
Serena Lecis, Giulia Bonfiglioli, Francesco Cannistrà, Sara Verra, Lucia Lisotti, Letizia Ramovecchi, Antonio Saddò, Giuseppe Chiossi, Riccardo Cuoghi Costantini, Roberto D'Amico, Sara Lazzarin, Fabio Facchinetti, Isabella Neri, Lara Donno, Massimo Girardis, Antonio La Marca, Francesca Monari

Background: : The use of epidural analgesia represents the gold standard for pain management during labor, however, the influence of the use of epidural analgesia on delivery mode and neonatal outcomes is not fully understood. Moreover, the rate of induction of labor worldwide is increasing dramatically.

Objective: : This study aimed to analyze the impact of epidural analgesia on the mode of parturition and perinatal outcomes among individuals classified as Robson class 2a.

Study design: A retrospective cohort study was conducted on every Robson class 2a individual who delivered from January 1, 2022, to December 31, 2023, at the University Hospital of Modena in the north of Italy. The primary outcome was the delivery mode (cesarean delivery, vaginal delivery, and operative vaginal delivery rates), and the secondary outcomes were the effect of epidural analgesia on the duration of labor, duration of the second stage of labor, Apgar score, and neonatal intensive care unit admission.

Results: Overall, 809 individuals were included in the final analysis, and 456 of them (56.4%) received epidural analgesia on request. Among individuals with and those without epidural analgesia, the cesarean delivery rate was 25% and 20.4% (P=.12), the vaginal delivery rate was 65.6% and 69.4% (P=.25), and the operative vaginal delivery rate was 9.4% and 10.2% (P=.72), respectively, without statistically significant differences. Furthermore, no significant difference was found in the neonatal outcomes between the 2 groups. Individuals with epidural analgesia had longer induction (P<.001) and second stage (P=.004) times than those without. These findings were confirmed by multivariable logistic and multinomial regression analyses. In the multivariable logistic regression, the increased induction time was associated not only with epidural analgesia (P<.001) but also with body mass index at delivery (P=.027), the gestational age at induction (P<.001), post-term pregnancy (P<.001), and induction indications of gestational diabetes or an estimated fetal weight >95th percentile (P<.001). Similarly, the increased duration of the second stage was associated not only with epidural analgesia (P=.026) but also with neonatal weight (P=.005) and induction indication for gestational diabetes or estimated fetal weight >95th percentile (P=.034).

Conclusion: Epidural analgesia was among the factors that increased both the induction and second stage of delivery times. However, epidural analgesia did not impact the mode of delivery and perinatal outcomes in Robson class 2a individuals.

背景:使用硬膜外镇痛是分娩过程中疼痛管理的金标准,然而,硬膜外镇痛对分娩方式和新生儿结局的影响尚不完全清楚。此外,世界范围内的引产率正在急剧上升。目的:本研究旨在分析Robson 2a类患者硬膜外镇痛对分娩方式和围产儿结局的影响。研究设计:对2022年1月1日至2023年12月31日在意大利北部摩德纳大学医院分娩的所有Robson 2a级患者进行回顾性队列研究。主要结局是分娩方式(剖宫产、阴道分娩和手术阴道分娩率),次要结局是硬膜外镇痛对分娩持续时间、第二产程持续时间、Apgar评分和新生儿重症监护病房入住的影响。结果:809例患者被纳入最终分析,其中456例(56.4%)接受了硬膜外镇痛。有硬膜外镇痛组与无硬膜外镇痛组剖宫产率分别为25%、20.4% (P= 0.12),阴道分娩率分别为65.6%、69.4% (P= 0.25),手术阴道分娩率分别为9.4%、10.2% (P= 0.72),差异无统计学意义。此外,两组新生儿结局无显著差异。硬膜外镇痛组诱导时间长(PP= 0.004)。这些发现被多变量逻辑分析和多项回归分析证实。在多变量logistic回归中,引产时间的增加不仅与硬膜外镇痛(PP= 0.027)、引产时胎龄(PP= 0.026)有关,还与新生儿体重(P= 0.005)、引产指征妊娠期糖尿病或估计胎儿体重bbb95百分位数(P= 0.034)有关。结论:硬膜外镇痛是增加引产时间和二期分娩时间的因素之一。然而,在Robson 2a类患者中,硬膜外镇痛并不影响分娩方式和围产期结局。
{"title":"Relation between epidural analgesia and perinatal outcomes on Robson class 2a.","authors":"Serena Lecis, Giulia Bonfiglioli, Francesco Cannistrà, Sara Verra, Lucia Lisotti, Letizia Ramovecchi, Antonio Saddò, Giuseppe Chiossi, Riccardo Cuoghi Costantini, Roberto D'Amico, Sara Lazzarin, Fabio Facchinetti, Isabella Neri, Lara Donno, Massimo Girardis, Antonio La Marca, Francesca Monari","doi":"10.1016/j.xagr.2025.100554","DOIUrl":"https://doi.org/10.1016/j.xagr.2025.100554","url":null,"abstract":"<p><strong>Background: </strong><b>:</b> The use of epidural analgesia represents the gold standard for pain management during labor, however, the influence of the use of epidural analgesia on delivery mode and neonatal outcomes is not fully understood. Moreover, the rate of induction of labor worldwide is increasing dramatically.</p><p><strong>Objective: </strong><b>:</b> This study aimed to analyze the impact of epidural analgesia on the mode of parturition and perinatal outcomes among individuals classified as Robson class 2a.</p><p><strong>Study design: </strong>A retrospective cohort study was conducted on every Robson class 2a individual who delivered from January 1, 2022, to December 31, 2023, at the University Hospital of Modena in the north of Italy. The primary outcome was the delivery mode (cesarean delivery, vaginal delivery, and operative vaginal delivery rates), and the secondary outcomes were the effect of epidural analgesia on the duration of labor, duration of the second stage of labor, Apgar score, and neonatal intensive care unit admission.</p><p><strong>Results: </strong>Overall, 809 individuals were included in the final analysis, and 456 of them (56.4%) received epidural analgesia on request. Among individuals with and those without epidural analgesia, the cesarean delivery rate was 25% and 20.4% (<i>P</i>=.12), the vaginal delivery rate was 65.6% and 69.4% (<i>P</i>=.25), and the operative vaginal delivery rate was 9.4% and 10.2% (<i>P</i>=.72), respectively, without statistically significant differences. Furthermore, no significant difference was found in the neonatal outcomes between the 2 groups. Individuals with epidural analgesia had longer induction (<i>P</i><.001) and second stage (<i>P</i>=.004) times than those without. These findings were confirmed by multivariable logistic and multinomial regression analyses. In the multivariable logistic regression, the increased induction time was associated not only with epidural analgesia (<i>P</i><.001) but also with body mass index at delivery (<i>P</i>=.027), the gestational age at induction (<i>P</i><.001), post-term pregnancy (<i>P</i><.001), and induction indications of gestational diabetes or an estimated fetal weight >95th percentile (<i>P</i><.001). Similarly, the increased duration of the second stage was associated not only with epidural analgesia (<i>P</i>=.026) but also with neonatal weight (<i>P</i>=.005) and induction indication for gestational diabetes or estimated fetal weight >95th percentile (<i>P</i>=.034).</p><p><strong>Conclusion: </strong>Epidural analgesia was among the factors that increased both the induction and second stage of delivery times. However, epidural analgesia did not impact the mode of delivery and perinatal outcomes in Robson class 2a individuals.</p>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"6 1","pages":"100554"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12886058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146168005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare complication after common obstetric procedure: rectus sheath hematoma after amniocentesis treated with embolization case report 常见产科手术后罕见并发症:羊膜穿刺术后直肌鞘血肿栓塞治疗一例报告
Pub Date : 2025-08-05 DOI: 10.1016/j.xagr.2025.100551
Anna R. Ilivicky MD , Shreya S. Katwala BA , Julie A. Vircks DO, MBA , Teresa A. Orth MD, PhD
Rectus sheath hematomas are becoming more commonly diagnosed but are typically associated with high-risk patients, such as older adult patients, patients on anticoagulation, or patients with recent trauma. This case describes a woman who underwent genetic amniocentesis at 20 1/7 weeks of gestation with a resultant rectus sheath hematoma that began expanding after an exacerbation of the patient’s chronic obstructive pulmonary disease approximately 2 weeks after the patient’s amniocentesis procedure. Ultimately, embolization and coiling of the right inferior epigastric artery were required due to the expanding hematoma and worsening pain. Antibiotics were administered due to concern for a late complication of amniocentesis and a prolonged recovery with a large hematoma.
直肌鞘血肿的诊断越来越普遍,但通常与高危患者相关,如老年患者、抗凝治疗患者或近期创伤患者。本病例描述了一名妇女在妊娠20 1/7周时接受遗传性羊膜穿刺术,并在患者进行羊膜穿刺术约2周后慢性阻塞性肺疾病加重后出现直肌鞘血肿,血肿开始扩大。最终,由于血肿扩大和疼痛加重,需要栓塞和盘绕右腹壁下动脉。由于担心羊膜穿刺术的晚期并发症和大血肿的长期恢复,给予抗生素。
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引用次数: 0
Effect of education on endometriosis and mediating effects: a mendelian randomization study 教育对子宫内膜异位症的影响及其中介作用:一项孟德尔随机研究
Pub Date : 2025-08-01 DOI: 10.1016/j.xagr.2025.100559
Luhongyuan Jin , Chi Chi , Qin Zhang , Yueming Zhang , Guorong Han M.D. , Jun Lin M.D. , Wenjie Hou M.D.

Objectives

To assess the potential impact of years of education, which serves as a measure of socioeconomic inequality, on the occurrence of endometriosis, and to quantify the potential influence of modifiable factors as mediators.

Methods

The study used SNPs as genetic tools for genetic association. Analysis using 2-sample univariate and multivariate Mendelian randomization methods. Primary analyses were performed using an inverse variance weighted MR method. Data were obtained from publicly available genome-wide association studies (GWAS) from European populations. Data for ending endometriosis were obtained from the Neale lab.

Results

Each SD increase in years of education (4.2 years) has a protective effect on endometriosis (OR 0.9975; 95% CI 0.9958–0.9951). For individuals, the most significant contribution is the depression factor (mediation effect 53%, 95% CI: 3–102%). After combining, the mediator variable explains 64% (95% CI: 55%–290%) of the education—endometriosis association.

Summary

Higher education attainment potentially has a causal protective effect on endometriosis, while lower education levels may increase the risk of endometriosis through modifiable factors such as depression, insomnia, and anxiety.
目的评估作为社会经济不平等衡量指标的受教育年限对子宫内膜异位症发生的潜在影响,并量化可调节因素作为中介的潜在影响。方法采用单核苷酸多态性作为遗传工具进行遗传关联。采用双样本单变量和多变量孟德尔随机化方法进行分析。使用反方差加权MR方法进行初步分析。数据来自欧洲人群的公开全基因组关联研究(GWAS)。终止子宫内膜异位症的数据来自尼尔实验室。结果受教育年限每增加一个SD(4.2年)对子宫内膜异位症有保护作用(OR 0.9975; 95% CI 0.9958 ~ 0.9951)。对个体而言,最显著的贡献是抑郁因素(中介效应53%,95% CI: 3-102%)。综合后,中介变量解释了64% (95% CI: 55%-290%)的教育与子宫内膜异位症的关联。高等教育程度可能对子宫内膜异位症有潜在的因果保护作用,而低教育水平可能通过抑郁、失眠和焦虑等可变因素增加子宫内膜异位症的风险。
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引用次数: 0
Biomarkers predicting adverse pregnancy outcomes in women living with obesity: a systematic review and meta-analysis 预测肥胖妇女不良妊娠结局的生物标志物:系统回顾和荟萃分析
Pub Date : 2025-08-01 DOI: 10.1016/j.xagr.2025.100527
Tabitha Wishlade MSc , Sara Wetzler MPhil , Catherine E. Aiken PhD

Objective

To systematically review the literature on associations between antenatal biomarkers and adverse pregnancy outcomes in women with BMI ≥30 kg/m². Data sources: Systematic literature searches used predefined search terms in PubMed, Ovid Embase, Ovid MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials. Databases were searched from inception to August 2024.

Study eligibility criteria

Interventional and observational studies comparing pregnancy outcomes amongst women with a pre- or early-pregnancy (<20 weeks’ gestation) BMI ≥30 kg/m² according to presence or amount of any antenatally measured biomarker were included.

Study appraisal and synthesis methods

Two reviewers independently assessed studies for inclusion against predefined inclusion and exclusion criteria. Risk of bias assessment was performed on included studies using the Newcastle-Ottawa Risk of Bias Tool. A narrative synthesis of eligible studies was constructed and data were meta-analysed, where possible, using random effects models. Certainty of evidence was assessed by GRADE rating.

Results

Total 49 studies were included in the review, representing >500 different biomarkers in 7479 pregnancies across 16 countries. Adiponectin was the only biomarker with sufficient data to meta-analyse with respect to the composite outcome. Lower adiponectin was associated with increased risk of the composite outcome (SMD −0.52, 95% CI −0.63, −0.41; P<.001, I2 0%). Lower adiponectin was also associated with increased risk of gestational diabetes (SMD −0.57, 95% CI −0.70, −0.43; P<.001, I2 0%) and pre-eclampsia (OR 0.65, 95% CI 0.44, 0.99; P=.047, I2 61.5%). Increased insulin concentrations were associated with gestational diabetes (SMD 0.35, 95% CI 0.22, −0.47; P<.001, I2 0%). Certainty of evidence regarding all associations was low or very low.

Conclusions

Decreased adiponectin and increased insulin are associated with increased risk of adverse pregnancy outcomes in women with BMI ≥30 kg/m². However, the low number of studies available for inclusion and low certainty of evidence mean that biomarker-based risk-stratification within pregnant women with BMI ≥30 kg/m² is not currently feasible. Further research is required to find ways of reliably targeting investigations during maternity care towards the subset of women living with obesity who are at highest risk of adverse outcomes.
目的系统回顾BMI≥30 kg/m²孕妇产前生物标志物与不良妊娠结局的相关文献。数据来源:系统文献搜索使用预先定义的搜索词在PubMed, Ovid Embase, Ovid MEDLINE, Scopus和Cochrane中央对照试验注册。数据库从成立到2024年8月进行了搜索。研究资格标准纳入了比较孕前或妊娠早期(妊娠20周)BMI≥30 kg/m²(根据产前测量的任何生物标志物的存在或数量)的妇女妊娠结局的干预性和观察性研究。研究评价和综合方法两名审稿人根据预先确定的纳入和排除标准独立评估研究。使用纽卡斯尔-渥太华偏倚风险工具对纳入的研究进行偏倚风险评估。构建了符合条件的研究的叙事综合,并在可能的情况下使用随机效应模型对数据进行了荟萃分析。证据的确定性采用GRADE评定。结果本综述共纳入49项研究,代表了16个国家7479例妊娠的500种不同的生物标志物。脂联素是唯一具有足够数据的生物标志物,可以对复合结果进行meta分析。低脂联素与复合结局的风险增加相关(SMD = - 0.52, 95% CI = - 0.63, - 0.41; P< = 0.001, i2%)。低脂联素还与妊娠期糖尿病(SMD = - 0.57, 95% CI = - 0.70, - 0.43; P< = 0.001, i2%)和先兆子痫(OR = 0.65, 95% CI = 0.44, 0.99; P= 0.047, i61.5%)的风险增加相关。胰岛素浓度升高与妊娠期糖尿病相关(SMD 0.35, 95% CI 0.22, - 0.47; P< 0.001, i20 %)。所有关联的证据的确定性都很低或非常低。结论脂联素降低和胰岛素升高与BMI≥30 kg/m²女性不良妊娠结局风险增加相关。然而,可纳入的研究数量少,证据的确定性低,这意味着在BMI≥30 kg/m²的孕妇中进行基于生物标志物的风险分层目前尚不可行。需要进一步的研究,以找到在产妇护理期间可靠地针对不良后果风险最高的肥胖妇女群体进行调查的方法。
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引用次数: 0
Contraceptive utilization and associated factors among reproductive age women attending psychiatric outpatient services, at northwest Amhara regional referral hospitals, Ethiopia 埃塞俄比亚阿姆哈拉西北地区转诊医院接受精神科门诊服务的育龄妇女的避孕药具使用情况及其相关因素
Pub Date : 2025-08-01 DOI: 10.1016/j.xagr.2025.100530
Getanew Kegnie Nigate MPH , Yohannes Ayanaw Habitu PhD , Worku Chekol Tassew MSc , Yeshiwas Ayale Ferede MPH , Elsa Awoke Fentie MPH

Introduction

Family planning is essential for all reproductive age women, and it is particularly Important for women with mental illness. Women with mental illness have a special need for Family planning as they carry a high risk of unplanned or unwanted pregnancy, sexual violence And poor obstetric outcomes. However, regarding contraceptive utilization and associated Factors among women with mental illness in low–income countries including Ethiopia is not Adequately explored.

Objective

To assess the magnitude of contraceptive utilization and associated factors among reproductive age women attending psychiatric outpatient services, at the northwest Amhara regional referral hospitals, Ethiopia

Methods

An institutional–based cross-sectional study was conducted among 810 study participants. A systematic random sampling technique was employed to recruit study participants. A structured and pretested questionnaire was used to collect the data. Data was entered in Epi data 3.1 and then exported to Stata version 14 for analysis. Model fitness was checked by using Hosmer and Lemeshow goodness. Both bivariable and multivariable logistic regressions were used to identify factors associated with contraceptive utilization among psychiatric outpatients. In multivariable logistic regression variables having a P-value less than 0.05 with 95% CI were considered as independently associated factors for the outcome Variable.

Result

About 42.59% (CI: 39.18–46.0) of the respondents were using family planning Contraceptive methods at the time of the study. Higher educational level (AOR=3.84 [95% CI: 1.81–8.16]), women who had no intention to have children in the future (AOR=1.53 [95% CI:1.02–2.30]), women counseled about family planning contraceptive method by a clinician (AOR=4.06 [95% CI:2.53–6.49]), good knowledge of family planning (AOR=2.77 [95% CI:1.90–4.03]), fear of side effect of psychiatric medication (AOR=1.57 [95% CI:1.09–2.25]) were factors associated with contraceptive utilization.

Conclusion and recommendation

Approximately 42.59% of women with psychiatric illnesses were using modern family planning methods. Significant predictors included having a higher education, good knowledge of family planning, not planning to have children in the future, believing that psychiatric medications are compatible with family planning, and receiving counseling on modern methods from healthcare providers. It is essential for healthcare providers to enhance family planning counseling in mental health clinics to improve knowledge and utilization of these methods.
计划生育对所有育龄妇女至关重要,对患有精神疾病的妇女尤其重要。患有精神疾病的妇女特别需要计划生育,因为她们面临意外怀孕或意外怀孕、性暴力和不良产科结果的高风险。然而,在包括埃塞俄比亚在内的低收入国家中,关于精神病妇女的避孕药具使用和相关因素尚未得到充分探讨。目的评估在阿姆哈拉西北部地区转诊医院接受精神科门诊服务的育龄妇女避孕药具使用率及其相关因素。埃塞俄比亚方法对810名研究参与者进行了基于机构的横断面研究。采用系统随机抽样技术招募研究参与者。采用结构化的预测问卷来收集数据。数据在Epi Data 3.1中输入,然后导出到Stata version 14进行分析。模型适应度采用Hosmer和Lemeshow优度进行检验。采用双变量和多变量logistic回归来确定精神科门诊患者避孕药具使用的相关因素。在多变量逻辑回归中,p值小于0.05且95% CI的变量被认为是结果变量的独立相关因素。结果42.59% (CI: 39.18 ~ 46.0)的调查对象在调查时正在采取计划生育避孕措施。较高的受教育程度(AOR=3.84 [95% CI: 1.81-8.16])、未来不打算生育的妇女(AOR=1.53 [95% CI: 1.02-2.30])、临床医生对计划生育避孕方法的咨询(AOR=4.06 [95% CI: 2.53-6.49])、良好的计划生育知识(AOR=2.77 [95% CI: 1.90-4.03])、对精神药物副作用的恐惧(AOR=1.57 [95% CI: 1.09-2.25])是避孕药具使用的相关因素。结论与建议约42.59%的精神疾病妇女采用现代计划生育方法。重要的预测因素包括受过高等教育,对计划生育有良好的了解,不打算将来要孩子,相信精神科药物与计划生育是相容的,并接受医疗保健提供者关于现代方法的咨询。应加强心理卫生诊所的计划生育咨询,提高对这些方法的认识和利用。
{"title":"Contraceptive utilization and associated factors among reproductive age women attending psychiatric outpatient services, at northwest Amhara regional referral hospitals, Ethiopia","authors":"Getanew Kegnie Nigate MPH ,&nbsp;Yohannes Ayanaw Habitu PhD ,&nbsp;Worku Chekol Tassew MSc ,&nbsp;Yeshiwas Ayale Ferede MPH ,&nbsp;Elsa Awoke Fentie MPH","doi":"10.1016/j.xagr.2025.100530","DOIUrl":"10.1016/j.xagr.2025.100530","url":null,"abstract":"<div><h3>Introduction</h3><div>Family planning is essential for all reproductive age women, and it is particularly Important for women with mental illness. Women with mental illness have a special need for Family planning as they carry a high risk of unplanned or unwanted pregnancy, sexual violence And poor obstetric outcomes. However, regarding contraceptive utilization and associated Factors among women with mental illness in low–income countries including Ethiopia is not Adequately explored.</div></div><div><h3>Objective</h3><div>To assess the magnitude of contraceptive utilization and associated factors among reproductive age women attending psychiatric outpatient services, at the northwest Amhara regional referral hospitals, Ethiopia</div></div><div><h3>Methods</h3><div>An institutional–based cross-sectional study was conducted among 810 study participants. A systematic random sampling technique was employed to recruit study participants. A structured and pretested questionnaire was used to collect the data. Data was entered in Epi data 3.1 and then exported to Stata version 14 for analysis. Model fitness was checked by using Hosmer and Lemeshow goodness. Both bivariable and multivariable logistic regressions were used to identify factors associated with contraceptive utilization among psychiatric outpatients. In multivariable logistic regression variables having a <em>P</em>-value less than 0.05 with 95% CI were considered as independently associated factors for the outcome Variable.</div></div><div><h3>Result</h3><div>About 42.59% (CI: 39.18–46.0) of the respondents were using family planning Contraceptive methods at the time of the study. Higher educational level (AOR=3.84 [95% CI: 1.81–8.16]), women who had no intention to have children in the future (AOR=1.53 [95% CI:1.02–2.30]), women counseled about family planning contraceptive method by a clinician (AOR=4.06 [95% CI:2.53–6.49]), good knowledge of family planning (AOR=2.77 [95% CI:1.90–4.03]), fear of side effect of psychiatric medication (AOR=1.57 [95% CI:1.09–2.25]) were factors associated with contraceptive utilization.</div></div><div><h3>Conclusion and recommendation</h3><div>Approximately 42.59% of women with psychiatric illnesses were using modern family planning methods. Significant predictors included having a higher education, good knowledge of family planning, not planning to have children in the future, believing that psychiatric medications are compatible with family planning, and receiving counseling on modern methods from healthcare providers. It is essential for healthcare providers to enhance family planning counseling in mental health clinics to improve knowledge and utilization of these methods.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 3","pages":"Article 100530"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145094730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postpartum care screenings by care modality among US mothers, 2020–2021 2020-2021年美国母亲按护理方式进行的产后护理筛查
Pub Date : 2025-08-01 DOI: 10.1016/j.xagr.2025.100541
Don E. Willis PhD , Cari A. Bogulski PhD , Clare C. Brown PhD , Nirvana A. Manning MD , Lanita S. White PharmD , James P. Selig PhD , Ji Li MS , Pearl A. McElfish PhD

BACKGROUND

Postpartum care is critical to preventing pregnancy-associated deaths. Virtual modes of care have potential to improve access to postpartum care; however, the impact on postpartum screenings for cigarette smoking, emotional/physical abuse, and depression is unknown.

OBJECTIVE

The purpose of this study was to compare receipt of these screenings between mothers who received any virtual postpartum care and those whose care was exclusively in-person.

STUDY DESIGN

Using the Pregnancy Risk Assessment Monitoring System Phase 8 data, we estimated receipt of postpartum care screenings for smoking, emotional/physical abuse, and depression for US mothers during COVID-19 (2020–2021) and assessed differences by mode of care. The analytical sample (n=21,815) included mothers from 28 Pregnancy Risk Assessment Monitoring System study sites who had postpartum care and answered the mode of care question and all 3 postpartum screening questions.

RESULTS

Over half of all mothers were screened for cigarette smoking (56.45%) and emotional/physical abuse (59.28%) during their postpartum care, whereas screening for depression was much more prevalent (87.63%). A higher percentage of screenings for smoking, emotional/physical abuse, and depression was reported for mothers who received any virtual postpartum care compared with those who attended exclusively in-person care (all P<.001). After adjusting for covariates, the prevalence of screening for cigarette smoking, emotional/physical abuse, and depression was 14%, 18%, and 6% higher, respectively, among mothers who received any virtual (vs. exclusively in-person) postpartum care.

CONCLUSION

Virtual postpartum care may improve the percentage of women receiving screenings for important maternal health risks and behaviors, such as cigarette smoking, emotional/physical abuse, and depression. Further research is needed to determine whether mothers receiving virtual postpartum care are more likely to receive screenings because of the mode of care itself.
产后护理对预防妊娠相关死亡至关重要。虚拟护理模式有可能改善获得产后护理的机会;然而,对产后吸烟、情绪/身体虐待和抑郁症筛查的影响尚不清楚。目的本研究的目的是比较接受任何虚拟产后护理的母亲和那些完全面对面护理的母亲接受这些筛查的情况。研究设计:使用妊娠风险评估监测系统第8期数据,我们估计了美国母亲在COVID-19(2020-2021)期间接受吸烟、情绪/身体虐待和抑郁的产后护理筛查的情况,并评估了护理模式的差异。分析样本(n=21,815)包括来自28个妊娠风险评估监测系统研究站点的接受产后护理并回答护理模式问题和所有3个产后筛查问题的母亲。结果超过一半的母亲在产后护理中接受了吸烟(56.45%)和精神/身体虐待(59.28%)的筛查,而抑郁症的筛查更为普遍(87.63%)。据报道,接受虚拟产后护理的母亲接受吸烟、情绪/身体虐待和抑郁症筛查的比例高于只接受面对面护理的母亲(P<.001)。在调整协变量后,接受虚拟产后护理的母亲中,吸烟、情绪/身体虐待和抑郁筛查的患病率分别高出14%、18%和6%。结论虚拟产后护理可提高接受重要孕产妇健康风险和行为筛查的妇女比例,如吸烟、情绪/身体虐待和抑郁。需要进一步的研究来确定接受虚拟产后护理的母亲是否因为护理模式本身而更有可能接受筛查。
{"title":"Postpartum care screenings by care modality among US mothers, 2020–2021","authors":"Don E. Willis PhD ,&nbsp;Cari A. Bogulski PhD ,&nbsp;Clare C. Brown PhD ,&nbsp;Nirvana A. Manning MD ,&nbsp;Lanita S. White PharmD ,&nbsp;James P. Selig PhD ,&nbsp;Ji Li MS ,&nbsp;Pearl A. McElfish PhD","doi":"10.1016/j.xagr.2025.100541","DOIUrl":"10.1016/j.xagr.2025.100541","url":null,"abstract":"<div><h3>BACKGROUND</h3><div>Postpartum care is critical to preventing pregnancy-associated deaths. Virtual modes of care have potential to improve access to postpartum care; however, the impact on postpartum screenings for cigarette smoking, emotional/physical abuse, and depression is unknown.</div></div><div><h3>OBJECTIVE</h3><div>The purpose of this study was to compare receipt of these screenings between mothers who received any virtual postpartum care and those whose care was exclusively in-person.</div></div><div><h3>STUDY DESIGN</h3><div>Using the Pregnancy Risk Assessment Monitoring System Phase 8 data, we estimated receipt of postpartum care screenings for smoking, emotional/physical abuse, and depression for US mothers during COVID-19 (2020–2021) and assessed differences by mode of care. The analytical sample (n=21,815) included mothers from 28 Pregnancy Risk Assessment Monitoring System study sites who had postpartum care and answered the mode of care question and all 3 postpartum screening questions.</div></div><div><h3>RESULTS</h3><div>Over half of all mothers were screened for cigarette smoking (56.45%) and emotional/physical abuse (59.28%) during their postpartum care, whereas screening for depression was much more prevalent (87.63%). A higher percentage of screenings for smoking, emotional/physical abuse, and depression was reported for mothers who received any virtual postpartum care compared with those who attended exclusively in-person care (all <em>P</em>&lt;.001). After adjusting for covariates, the prevalence of screening for cigarette smoking, emotional/physical abuse, and depression was 14%, 18%, and 6% higher, respectively, among mothers who received any virtual (vs. exclusively in-person) postpartum care.</div></div><div><h3>CONCLUSION</h3><div>Virtual postpartum care may improve the percentage of women receiving screenings for important maternal health risks and behaviors, such as cigarette smoking, emotional/physical abuse, and depression. Further research is needed to determine whether mothers receiving virtual postpartum care are more likely to receive screenings because of the mode of care itself.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 3","pages":"Article 100541"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144750319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expulsion rates 12 months after early versus interval postpartum intrauterine device placement: a randomized trial 早期与产后间隔放置宫内节育器后12个月排出率:一项随机试验
Pub Date : 2025-08-01 DOI: 10.1016/j.xagr.2025.100547
Sarah Averbach MD, MAS , Florin Vaida PhD , Erica Hinz MD, MPH , Gennifer Kully MSc , Arnab K. Dey PhD, MBA , Monica A. Lutgendorf MD , Sadia Haider MD, MPH , Lisa G. Hofler MD, MPH, MBA

Objective

The early postpartum period, 2 to 4 weeks postpartum, is an optimal time for intrauterine device (IUD) initiation; placement can be co-located with early postpartum or infant visits. We aimed to compare expulsion rates at 12 months postpartum for IUDs placed early compared to the standard interval 6-week visit.

Study Design

This is a randomized controlled trial conducted at four U.S. medical centers. Participants were randomly assigned to early (14–28 days) or interval (42–56 days) postpartum IUD placement after vaginal or cesarean birth. We used transvaginal ultrasound to confirm IUD presence and position at 6 months. Chart review and telephone surveys were used to verify IUD presence and position at 12 months.

Results

Between March 2018 and June 2021, 203 participants were assigned to early and 201 to interval IUD placement; 238 (58.9%) contributed outcome data by phone survey (and electronic medical record review) at 12-months postpartum. Among participants who received an IUD and provided 12-month outcome data, complete expulsion rates were 4 in 124 (3.2%; 95% confidence interval [CI], 0.90 to 8.2) and 0 in 114 (0%; 95% CI, 0 to 3.2) in the early and interval groups; a between-group difference of 3.2 percentage points (95% CI, −0.01 to 8.0, P=.054). Partial expulsion counts and rates were 16 (12.9%; 95% CI, 7.6 to 20.1) and 13 (11.4%; 95% CI, 6.2 to 18.7) in the early and interval groups; a difference of 1.5 percentage points (95% CI, −7.2 to 10.2, P=.75). Among all 404 participants, IUD utilization rates at 12-month follow-up were 113 (55.7%; 95% CI, 48.5 to 62.6 among participants in the early group) compared to 95 (47.3%; 95% CI, 40.2 to 54.1, P=.10 among participants in the interval group). Participants were more satisfied with early compared to interval placement, 107 (86.3%; 95% CI 79.0 to 91.8) vs 87 (76.3%, 95% CI 67.4 to 83.8 95%) P=.048.

Conclusion

Complete expulsion rates at 12 months are low (<5%) when IUDs are placed in the early and interval postpartum period. Satisfaction is higher with early postpartum IUD placement.
目的产后2 ~ 4周为宫内节育器启动的最佳时间;安置地点可以与产后早期或婴儿探视同时进行。我们的目的是比较早期放置宫内节育器与标准间隔6周访问的产后12个月排出率。研究设计这是一项在美国四家医疗中心进行的随机对照试验。参与者被随机分配到阴道分娩或剖宫产后早期(14-28天)或间隔(42-56天)放置宫内节育器。我们在6个月时使用阴道超声确认宫内节育器的存在和位置。使用图表审查和电话调查来验证12个月时宫内节育器的存在和位置。结果2018年3月至2021年6月,203名参与者被分配到早期放置,201名参与者被分配到间隔放置;238例(58.9%)通过产后12个月的电话调查(和电子病历审查)提供了结果数据。在接受宫内节育器并提供12个月结局数据的参与者中,完全排出率为124分之4 (3.2%;95%置信区间[CI], 0.90 ~ 8.2), 114例为0 (0%;早期组和间隔组的95% CI为0 ~ 3.2);组间差异为3.2个百分点(95% CI, - 0.01至8.0,P= 0.054)。部分开除计数和率16例(12.9%;95% CI, 7.6 - 20.1)和13 (11.4%;早期组和间歇组的95% CI为6.2 ~ 18.7);差异为1.5个百分点(95% CI, - 7.2至10.2,P=.75)。在404名参与者中,12个月随访时宫内节育器使用率为113 (55.7%;早期组的95% CI为48.5 - 62.6,而早期组的95% CI为95 (47.3%;95% CI, 40.2 ~ 54.1, P=。10人(间歇组)。与间隔放置相比,参与者对早期更满意,107 (86.3%;95% CI 79.0 ~ 91.8) vs 87 (76.3%, 95% CI 67.4 ~ 83.8 95%) P= 0.048。结论宫内节育器放置在产后早期和间隔期,12个月完全排出率较低(5%)。产后早期放置宫内节育器满意度较高。
{"title":"Expulsion rates 12 months after early versus interval postpartum intrauterine device placement: a randomized trial","authors":"Sarah Averbach MD, MAS ,&nbsp;Florin Vaida PhD ,&nbsp;Erica Hinz MD, MPH ,&nbsp;Gennifer Kully MSc ,&nbsp;Arnab K. Dey PhD, MBA ,&nbsp;Monica A. Lutgendorf MD ,&nbsp;Sadia Haider MD, MPH ,&nbsp;Lisa G. Hofler MD, MPH, MBA","doi":"10.1016/j.xagr.2025.100547","DOIUrl":"10.1016/j.xagr.2025.100547","url":null,"abstract":"<div><h3>Objective</h3><div>The early postpartum period, 2 to 4 weeks postpartum, is an optimal time for intrauterine device (IUD) initiation; placement can be co-located with early postpartum or infant visits. We aimed to compare expulsion rates at 12 months postpartum for IUDs placed early compared to the standard interval 6-week visit.</div></div><div><h3>Study Design</h3><div>This is a randomized controlled trial conducted at four U.S. medical centers. Participants were randomly assigned to early (14–28 days) or interval (42–56 days) postpartum IUD placement after vaginal or cesarean birth. We used transvaginal ultrasound to confirm IUD presence and position at 6 months. Chart review and telephone surveys were used to verify IUD presence and position at 12 months.</div></div><div><h3>Results</h3><div>Between March 2018 and June 2021, 203 participants were assigned to early and 201 to interval IUD placement; 238 (58.9%) contributed outcome data by phone survey (and electronic medical record review) at 12-months postpartum. Among participants who received an IUD and provided 12-month outcome data, complete expulsion rates were 4 in 124 (3.2%; 95% confidence interval [CI], 0.90 to 8.2) and 0 in 114 (0%; 95% CI, 0 to 3.2) in the early and interval groups; a between-group difference of 3.2 percentage points (95% CI, −0.01 to 8.0, <em>P</em>=.054). Partial expulsion counts and rates were 16 (12.9%; 95% CI, 7.6 to 20.1) and 13 (11.4%; 95% CI, 6.2 to 18.7) in the early and interval groups; a difference of 1.5 percentage points (95% CI, −7.2 to 10.2, <em>P</em>=.75). Among all 404 participants, IUD utilization rates at 12-month follow-up were 113 (55.7%; 95% CI, 48.5 to 62.6 among participants in the early group) compared to 95 (47.3%; 95% CI, 40.2 to 54.1, <em>P</em>=.10 among participants in the interval group). Participants were more satisfied with early compared to interval placement, 107 (86.3%; 95% CI 79.0 to 91.8) vs 87 (76.3%, 95% CI 67.4 to 83.8 95%) <em>P</em>=.048<strong>.</strong></div></div><div><h3>Conclusion</h3><div>Complete expulsion rates at 12 months are low (&lt;5%) when IUDs are placed in the early and interval postpartum period. Satisfaction is higher with early postpartum IUD placement.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"5 3","pages":"Article 100547"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144841432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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AJOG global reports
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