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Annals of vascular surgery. Brief reports and innovations最新文献

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Left internal mammary artery supplying collateral circulation to the epigastric arteries is circumvented with axillofemoral bypass permitting coronary artery bypass grafting and mitral valve repair 左乳内动脉为腹壁动脉提供侧支循环,经腋股旁路术绕过,允许冠状动脉旁路移植术和二尖瓣修复
Pub Date : 2025-09-06 DOI: 10.1016/j.avsurg.2025.100405
Brady Antolick , Andrew D. Vogel , Schafer Paladichuk , Melissa Obmann , Christopher Demaioribus , Tyler J. Wallen

Introduction

Aortoiliac occlusive disease (AIOD) is a subset of peripheral artery disease (PAD) characterized by occlusion of the infrarenal aorta and iliac arteries. Patients with AIOD may develop collateral circulation through the internal thoracic artery–inferior epigastric artery (ITA-IEA) pathway to maintain lower extremity perfusion. Coronary artery disease (CAD) often necessitates coronary artery bypass grafting (CABG), where the left internal mammary artery (LIMA) is the preferred conduit for revascularizing the left anterior descending (LAD) artery. In patients with AIOD, disruption of ITA-IEA collaterals during CABG poses a risk of exacerbating lower extremity ischemia.

Case description

We report a case of a 65-year-old female with severe multivessel CAD, mitral valve regurgitation (MVR), and AIOD with ITA-IEA collaterals supplying the lower extremities. Preoperative imaging revealed an occluded distal aorta with inadequate venous conduits. To preserve lower extremity perfusion, the patient underwent axillary-femoral and femoral-femoral bypasses before CABG. A two-vessel CABG was performed using the LIMA to the LAD and the radial artery to the obtuse marginal artery, along with mitral valve replacement. The patient recovered well and was discharged 11 days postoperatively without complications.

Discussion

This case highlights the complexities of managing concurrent AIOD and CAD, emphasizing the importance of preserving collateral circulation. Preoperative imaging enabled strategic surgical planning to balance myocardial revascularization and lower extremity perfusion. The successful use of alternative conduits, such as the radial artery, underscores the necessity of flexibility in graft selection. Multidisciplinary collaboration and individualized surgical planning are crucial in managing patients with AIOD and CAD.
主动脉髂动脉闭塞性疾病(AIOD)是外周动脉疾病(PAD)的一个子集,其特征是肾下主动脉和髂动脉闭塞。AIOD患者可能通过胸内动脉-腹壁下动脉(ITA-IEA)通路发展侧支循环来维持下肢灌注。冠状动脉疾病(CAD)通常需要冠状动脉旁路移植术(CABG),其中左乳内动脉(LIMA)是左前降支(LAD)血管重建的首选管道。在AIOD患者中,CABG期间ITA-IEA侧支的中断有加剧下肢缺血的风险。病例描述我们报告一例65岁女性,患有严重的多血管CAD,二尖瓣反流(MVR)和AIOD,并伴有ITA-IEA侧支供应下肢。术前影像学显示远端主动脉闭塞,静脉导管不足。为了保持下肢血流灌注,患者在CABG前进行了腋窝-股动脉和股动脉旁路手术。使用LIMA到LAD和桡动脉到钝边缘动脉进行双血管冠脉搭桥,同时进行二尖瓣置换术。患者恢复良好,术后11天出院,无并发症。本病例强调了同时处理AIOD和CAD的复杂性,强调了保持侧支循环的重要性。术前影像学检查使有策略的手术计划能够平衡心肌血运重建和下肢灌注。替代导管(如桡动脉)的成功应用强调了移植物选择灵活性的必要性。多学科合作和个体化手术计划是治疗AIOD和CAD患者的关键。
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引用次数: 0
Iatrogenic femoral complex pseudoaneurysm: A case report 医源性股复合体假性动脉瘤1例
Pub Date : 2025-09-01 DOI: 10.1016/j.avsurg.2025.100403
Rupendra Nath Saha , Bhanu Duggal , Raghuraj Chawla , Shubham Rawat
An iatrogenic complex femoral pseudoaneurysm, though rare, is associated with much comorbidity. We want to bring up a case of a complex pseudoaneurysm created after a percutaneous angioplasty, which was finally repaired using a surgical technique. The danger of rupture, embolisation, and infection are associated with complex femoral pseudoaneurysms. Though there are various ways of managing such a condition, an ideal approach should be tailored to each patient, considering their comorbidities. Surgical repair is still a practical and successful therapeutic option for these lesions, especially when endovascular or a conservative intervention is not advised or has not worked.
医源性复杂股假性动脉瘤,虽然罕见,但与许多合并症有关。我们想提出一个复杂的假性动脉瘤的情况下,经皮血管成形术后产生,这是最终修复使用手术技术。复杂股假性动脉瘤有破裂、栓塞和感染的危险。虽然有各种各样的方法来处理这种情况,但理想的方法应该针对每个病人,考虑到他们的合并症。手术修复仍然是这些病变的一个实用和成功的治疗选择,特别是当血管内或保守干预不建议或没有工作。
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引用次数: 0
Use of diverging buddy wires to aid in precise endovascular stent placement at an arterial branch point 在动脉分支点使用分散的金属丝辅助血管内支架的精确放置
Pub Date : 2025-08-27 DOI: 10.1016/j.avsurg.2025.100402
Thane Gehring, Joshua Gierman
Endovascular stent placement at or near arterial branch points requires precision to avoid complications, including stent jumping or mal-deployment, with potential jailing of adjacent branch ostia. Here we describe the novel use of diverging buddy wires to ensure precise endovascular stent deployment in the innominate artery in a bovine arch initially managed by surgical primary repair. The use of divergent buddy wires provided stability in the complex anatomy, facilitating precise deployment at the arterial branch point with embolic protection in the carotid artery.
在动脉分支点或附近放置血管内支架需要精确,以避免并发症,包括支架跳跃或错误部署,以及潜在的相邻分支口监禁。在这里,我们描述了分散的兄弟钢丝的新用途,以确保精确的血管内支架部署在无名动脉的牛弓最初管理的外科初级修复。在复杂的解剖结构中,使用发散式金属丝提供了稳定性,便于在动脉分支点精确部署,并在颈动脉中提供栓塞保护。
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引用次数: 0
Stent occlusion after catheter-directed thrombolysis and iliac vein stenting in May-Thurner syndrome with iliofemoral deep vein thrombosis: A case report and literature review May-Thurner综合征伴髂股深静脉血栓形成患者经导管溶栓和髂静脉支架置入后支架闭塞1例并文献复习
Pub Date : 2025-08-24 DOI: 10.1016/j.avsurg.2025.100401
Haijun Huang, Zuoyi Yao, Ke Guo, Yunping Liu, Qian Zhang, Wei Wei, Kan Zhao

Background

Stent occlusion following endovascular management of May-Thurner syndrome (MTS) with iliofemoral deep vein thrombosis (DVT) remains a significant clinical challenge. This case report and literature review examines mechanical, procedural, and patient-specific determinants of stent failure in chronic venous disease.

Case Presentation

A 78-year-old female with acute left iliofemoral DVT post-hip arthroplasty underwent catheter-directed thrombolysis (CDT) and iliac vein stenting. Despite initial technical success and rivaroxaban therapy, stent occlusion occurred at 1-month follow-up, necessitating secondary stenting. Venography revealed residual thrombus at the inflow tract and incomplete coverage of the iliocaval confluence as likely contributors.

Literature Review

Analysis of 29 studies identified critical factors influencing stent patency:
Mechanical determinants: Larger stent diameter (≥16 mm) and optimized iliocaval confluence coverage reduced restenosis risk. In-stent shear rate >100 s⁻¹ and inflow luminal area >125 mm² correlated with patency.
Thrombotic risk: Chronic post-thrombotic lesions (residual thrombus >30 %) and antiphospholipid syndrome increased occlusion risk.
Anticoagulation: Combined anticoagulant/antiplatelet regimens reduced stent malfunction by 72 % (HR=0.28), while extended anticoagulation (6–12 months) showed no superiority over shorter durations in recent cohorts.

Conclusion

This case highlights the multifactorial nature of venous stent failure. Key recommendations include:
Aggressive thrombus clearance during CDT (<30 % residual burden)
IVUS-guided stent sizing to achieve optimal shear dynamics
Tailored anticoagulation incorporating thrombophilia screening
Anatomic precision in iliocaval confluence coverage
Prospective studies are needed to validate biomechanical thresholds and pharmacogenetic approaches in venous stent management.
背景:May-Thurner综合征(MTS)合并髂股深静脉血栓形成(DVT)的血管内治疗后支架闭塞仍然是一个重大的临床挑战。本病例报告和文献综述探讨了慢性静脉疾病中支架失效的机械、程序和患者特异性决定因素。一例78岁女性髋关节置换术后急性左髂股深静脉血栓形成,行导管溶栓(CDT)和髂静脉支架置入术。尽管最初的技术成功和利伐沙班治疗,支架闭塞发生在1个月的随访,需要二次支架置入。静脉造影显示流入道残留血栓和髂腔汇合处不完全覆盖可能是原因。文献综述:对29项研究的分析确定了影响支架通畅的关键因素:机械因素:较大的支架直径(≥16mm)和优化的髂腔汇合处覆盖可降低再狭窄风险。支架内剪切速率100 s⁻¹和流入腔面积125 mm²与通畅相关。血栓风险:慢性血栓后病变(残余血栓30%)和抗磷脂综合征增加闭塞风险。抗凝:在最近的队列研究中,抗凝/抗血小板联合治疗方案减少了72%的支架功能不全(HR=0.28),而延长抗凝治疗(6-12个月)并没有较短时间的优势。结论本病例突出了静脉支架失效的多因素性。主要建议包括:CDT期间积极清除血栓(30%残余负荷)ivus引导的支架尺寸以达到最佳剪切动力学;结合血栓形成筛查的量身定制抗凝治疗;髂腔静脉汇合处覆盖的解剖精度;需要前瞻性研究来验证生物力学阈值和药物遗传学方法在静脉支架管理中的应用。
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引用次数: 0
Measuring consistency: The reliability of pedal acceleration time measurements across and within raters 测量一致性:踏板加速时间测量跨和内部评级的可靠性
Pub Date : 2025-08-06 DOI: 10.1016/j.avsurg.2025.100400
Odette Hart , Philip Allan , Bridget August , Grant Abbott , Catherine Evans , Manar Khashram

Objectives

Pedal acceleration time (PAT) is a novel non-invasive lower limb perfusion assessment tool. However, the test-retest reliability between and within raters has not been examined. The aim of this pilot study was to assess the inter- and intra-rater reliability of PAT measurements.

Methods

Ten patients with diabetic foot and/or chronic limb threatening ischaemia underwent three repeated PAT measurements across three pedal arteries in a single limb by three trained sonographers. Inter-rater reliability was assessed as the contribution to variance by patients, raters, and replicates. Intra-rater reliability was quantified by the within-subject coefficient of variation (CV). The effects of raters and repeat measures was summarised using the intraclass correlation coefficient (ICC).

Results

Inter-rater reliability showed little contribution to variance at only ≤0.4 %, with ≥88.1 % of variance being that driven by patient variability. Intra-rater reliability as assessed by CV ranged between 10.8 %-12.2 %. The combined effect of raters and repeat measures assessed by ICC was 0.88–0.99 (good-to-excellent reliability).

Conclusions

This pilot study suggests PAT can be reliably measured by trained sonographers with good-to-excellent inter- and intra-rater reliability.
目的踏板加速时间(PAT)是一种新型的无创下肢血流灌注评估工具。然而,评估者之间和内部的重测信度尚未得到检验。这项初步研究的目的是评估PAT测量的内部和内部可靠性。方法10例糖尿病足和/或慢性肢体威胁性缺血患者,由三名训练有素的超声医师在单个肢体的三条足动脉上进行三次重复的PAT测量。评估者之间的信度是通过患者、评估者和重复对方差的贡献来评估的。受试者内变异系数(CV)量化受试者内信度。用类内相关系数(ICC)对评分者和重复措施的影响进行了总结。结果评分者间信度对方差的贡献很小,仅为≤0.4%,其中≥88.1%的方差是由患者的可变性驱动的。用CV评估的评分者内信度在10.8% - 12.2%之间。通过ICC评估的评分者和重复测量者的综合效果为0.88-0.99(信度从良到优)。结论:本初步研究表明,经过训练的超声医师可以可靠地测量PAT,并具有良好到优异的内部和内部可靠性。
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引用次数: 0
Aortoiliac graft occlusion presenting as lumbar plexopathy: a report of reversible neurological deficit 主动脉髂移植物闭塞表现为腰丛病:一份可逆性神经功能缺损的报告
Pub Date : 2025-07-19 DOI: 10.1016/j.avsurg.2025.100399
Andrea Muniz, Houssam Farres, Camilo Polania-Sandoval, Young Erben
Ischemic lumbar plexopathy is a rare and challenging neurological complication resulting from vascular insufficiency. Its clinical presentation varies, making diagnosis difficult and often leading to it being overlooked. Although it has been documented following aortic reconstruction procedures, complete neurologic recovery after revascularization has not previously been reported. We present the case of a 79-year-old male patient with a history of EVAR for the treatment of an infrarenal abdominal aortic aneurysm utilizing an aortouniiliac endograft and a left-to-right femoral-femoral bypass, who presented with acute left lower extremity pain and progressive weakness of bilateral lower extremities. Evaluation revealed acute occlusion of both the endograft and femoral-femoral bypass. He underwent left external iliac artery thrombectomy and a left axillary-to-femoral artery bypass, a redo left-to-right femoral-femoral bypass, and a left common femoral to above-knee popliteal artery bypass. This revascularization resulted in immediate sensory and motor function improvement. A review of fifteen published cases involving lumbar plexopathy after aortic interventions revealed typical presentation in the early postoperative period. Management was predominantly conservative, with nearly all patients receiving physical therapy, and one was treated with surgical revascularization via bypass. Despite these efforts, most patients experienced persistent motor deficits, with only one patient achieving full neurologic recovery through physical therapy alone. Ischemic lumbar plexopathy secondary to aortic graft occlusion is extremely rare. This case highlights the need to consider ischemic lumbar plexopathy in patients with complex vascular histories. Timely revascularization, even in a high-risk patient, led to meaningful neurological recovery.
缺血性腰丛病是一种罕见且具有挑战性的神经系统并发症,由血管功能不全引起。其临床表现各不相同,使诊断困难,往往导致它被忽视。虽然在主动脉重建手术后有文献记载,但在血管重建术后神经系统的完全恢复以前没有报道。我们报告了一位79岁男性患者的病例,他有EVAR的病史,利用动脉髂内移植物和左至右股-股分流术治疗肾下腹主动脉瘤,他表现为急性左下肢疼痛和双侧下肢进行性无力。评估显示急性闭塞的内移植物和股-股旁路。他接受了左髂外动脉血栓切除术和左腋窝至股动脉搭桥术、左至右股动脉搭桥术、左股总动脉至膝上腘动脉搭桥术。这种血运重建可立即改善感觉和运动功能。回顾15例已发表的经主动脉介入治疗后腰丛病的病例,发现典型的术后早期表现。治疗以保守为主,几乎所有患者均接受物理治疗,1例患者接受旁路手术血运重建术。尽管做出了这些努力,大多数患者仍然经历了持续的运动障碍,只有一名患者通过单独的物理治疗实现了神经功能的完全恢复。继发于主动脉瓣阻塞的缺血性腰丛病极为罕见。本病例强调有复杂血管病史的患者需要考虑缺血性腰丛病。及时的血运重建术,即使是高危患者,也能带来有意义的神经系统恢复。
{"title":"Aortoiliac graft occlusion presenting as lumbar plexopathy: a report of reversible neurological deficit","authors":"Andrea Muniz,&nbsp;Houssam Farres,&nbsp;Camilo Polania-Sandoval,&nbsp;Young Erben","doi":"10.1016/j.avsurg.2025.100399","DOIUrl":"10.1016/j.avsurg.2025.100399","url":null,"abstract":"<div><div>Ischemic lumbar plexopathy is a rare and challenging neurological complication resulting from vascular insufficiency. Its clinical presentation varies, making diagnosis difficult and often leading to it being overlooked. Although it has been documented following aortic reconstruction procedures, complete neurologic recovery after revascularization has not previously been reported. We present the case of a 79-year-old male patient with a history of EVAR for the treatment of an infrarenal abdominal aortic aneurysm utilizing an aortouniiliac endograft and a left-to-right femoral-femoral bypass, who presented with acute left lower extremity pain and progressive weakness of bilateral lower extremities. Evaluation revealed acute occlusion of both the endograft and femoral-femoral bypass. He underwent left external iliac artery thrombectomy and a left axillary-to-femoral artery bypass, a redo left-to-right femoral-femoral bypass, and a left common femoral to above-knee popliteal artery bypass. This revascularization resulted in immediate sensory and motor function improvement. A review of fifteen published cases involving lumbar plexopathy after aortic interventions revealed typical presentation in the early postoperative period. Management was predominantly conservative, with nearly all patients receiving physical therapy, and one was treated with surgical revascularization via bypass. Despite these efforts, most patients experienced persistent motor deficits, with only one patient achieving full neurologic recovery through physical therapy alone. Ischemic lumbar plexopathy secondary to aortic graft occlusion is extremely rare. This case highlights the need to consider ischemic lumbar plexopathy in patients with complex vascular histories. Timely revascularization, even in a high-risk patient, led to meaningful neurological recovery.</div></div>","PeriodicalId":72235,"journal":{"name":"Annals of vascular surgery. Brief reports and innovations","volume":"5 3","pages":"Article 100399"},"PeriodicalIF":0.0,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144694769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carotid body tumor presenting with acute internal carotid artery occlusion: Case report and review of the literature 颈动脉体肿瘤表现为急性颈内动脉闭塞:病例报告及文献复习
Pub Date : 2025-07-17 DOI: 10.1016/j.avsurg.2025.100397
Abdulrahman Saad Aldakkan
Carotid body tumors are the most common paragangliomas of the head and neck. Although stroke is a known potential complication following surgical resection, it is a very unusual presenting symptom. We present the fourth case in the literature of a carotid body tumor presenting with a stroke. A 37 year old male with acute right internal carotid artery occlusion in the presence of ipsilateral carotid body tumor. He was managed with endovascular thrombectomy. The clinical presentation, imaging findings and management are presented.
颈动脉体肿瘤是头颈部最常见的副神经节瘤。虽然中风是手术切除后已知的潜在并发症,但它是一种非常罕见的症状。我们提出的第四个病例,在文献颈动脉体肿瘤提出中风。一例37岁男性,急性右颈内动脉闭塞,伴有同侧颈动脉体肿瘤。他接受了血管内血栓切除术。本文介绍了临床表现、影像学表现和治疗方法。
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引用次数: 0
Management of an infected native aortic aneurysm secondary to an extremely rare pathogen - Cutibacterium acnes infection 一个受感染的原生主动脉瘤继发于一个极其罕见的病原体-痤疮表皮杆菌感染的处理
Pub Date : 2025-07-11 DOI: 10.1016/j.avsurg.2025.100398
Drake Giese , Buddhi P Hatharaliyadda , Tiziano Tallarita , Noora Jabeen , Yasser Almadani , Jason Beckermann , Indrani Sen
A 76-year-old male was treated for an incidentally diagnosed 6.6 cm infective native aortic aneurysm (INAA). He reported significant chronic back pain; but had no other clinical or radiological features of an infective or inflammatory aneurysm. He underwent open repair; aortic tissue culture was positive for Cutibacterium acnes. C. Acnes (previously known as Propionibacterium acnes) is an extremely rare etiology for INAA, there are no reports of long-term outcomes after open repair.1-4 He was treated with 6 weeks of IV ceftriaxone and remains on oral amoxicillin for chronic suppression with no reinfection on imaging and improvement in back pain.
一位76岁男性因偶然诊断为6.6 cm感染性原生主动脉瘤(INAA)而接受治疗。他报告有明显的慢性背痛;但没有感染性或炎症性动脉瘤的其他临床或影像学特征。他接受了开放性修复;主动脉组织培养对痤疮表皮杆菌阳性。痤疮(以前称为痤疮丙酸杆菌)是一种非常罕见的INAA病因,没有关于开放修复后长期结果的报道。1-4患者接受6周静脉注射头孢曲松治疗,并继续口服阿莫西林治疗慢性抑制,影像学无再感染,背部疼痛无改善。
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引用次数: 0
Surgical management of midaortic syndrome in children with renovascular hypertension: Over a quarter of century experience 儿童肾血管性高血压中腹主动脉综合征的手术治疗:超过25年的经验
Pub Date : 2025-07-09 DOI: 10.1016/j.avsurg.2025.100396
Afksendiyos Kalangos , Murat Ugurlucan , Didem Melis Oztas , Panagiotis Sfyridis , Gino Gemayel , Yilmaz Zorman , Nataliia Shatelen

Background

If left untreated, mid-aortic syndrome with renovascular hypertension can lead to life-threatening complications due to refractory hypertension. We aimed to analyze the medium- and long-term outcomes in a pediatric population that underwent surgery over the past 25 years.

Methods

A review of eight children with mid-aortic syndrome resulting in renovascular hypertension due to renal arterial stenosis has been conducted over the past 25 years. Children diagnosed with Takayasu arteritis were excluded. Primary outcomes were survival, reoperations, and interventional procedures.

Results

Eight children, with a median age of 12.5 years (ranging from 4 to 17 years old), were included in the study period. One patient had Neurofibromatosis type I, while another was diagnosed with Williams-Beuren syndrome. Seven children had involvement of one or both renal arteries, and most of them were affected by visceral abdominal aortic branches: celiac trunk (n = 3) and/or superior mesenteric artery (n = 2), which required reimplantation. The procedure to alleviate the stenotic abdominal aortic segment employed a lateral-to-end aorto-aortic bypass tube graft, with or without renal or visceral arterial bypass. There were no early or late deaths during the follow-up period. One patient experienced a postoperative thrombosis of the venous graft between the aortic bypass graft and the right renal artery, necessitating a thrombectomy. One patient required dilation of the right renal artery due to stenosis in the reimplanted artery 18 months after the initial repair, while another patient needed dilation of the superior mesenteric artery at the anastomosis with the saphenous vein graft after 19 months. In the remaining patients, imaging revealed no significant residual stenosis, and all patients were tapered off anti-hypertensive medications by the last follow-up appointment.

Conclusions

Surgical repair of the mid-aortic syndrome can be performed with low operative and late morbidity in experienced hands. Long-term follow-up is associated with complete resolution of renal hypertension. Patients require regular follow-up because of the risk of visceral aortic branch and renal artery anastomotic restenosis. However, revascularization using short saphenous vein graft segments is durable, and if stenosis occurs, it can be easily managed percutaneously.
背景:如果不及时治疗,中主动脉综合征合并肾血管性高血压可因难治性高血压导致危及生命的并发症。我们的目的是分析过去25年中接受手术的儿科人群的中期和长期结果。方法回顾性分析了25年来8例因肾动脉狭窄导致肾血管性高血压的中主动脉综合征患儿。诊断为高须动脉炎的儿童被排除在外。主要结局是生存、再手术和介入手术。结果8例儿童纳入研究,年龄4 ~ 17岁,中位年龄12.5岁。一名患者患有I型神经纤维瘤病,而另一名患者被诊断为威廉姆斯-伯伦综合征。7例患儿有单侧或双侧肾动脉受累,其中大多数受腹主动脉内脏分支影响:腹腔干(n = 3)和/或肠系膜上动脉(n = 2),需要再植。缓解腹主动脉段狭窄的手术采用外侧至端主动脉-主动脉搭桥管移植,伴或不伴肾或内脏动脉搭桥。随访期间无早死或晚死病例。1例患者术后主动脉旁路移植术与右肾动脉之间的静脉移植物血栓形成,需要取栓。1例患者在初次修复后18个月因移植动脉狭窄需要扩张右肾动脉,另1例患者在19个月后需要扩张与移植物隐静脉吻合处的肠系膜上动脉。在其余患者中,影像学显示没有明显的残余狭窄,并且所有患者在最后一次随访预约时逐渐停用抗高血压药物。结论在经验丰富的操作者手中,手术修复中主动脉综合征的手术率低,发病率晚。长期随访与肾性高血压的完全解决相关。由于存在内脏主动脉分支和肾动脉吻合口再狭窄的风险,患者需要定期随访。然而,使用短隐静脉移植物段进行血运重建是持久的,如果发生狭窄,可以很容易地经皮处理。
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引用次数: 0
Aneurysmal degeneration after drug-eluting stent implantation in lower limb arteries: A systematic review and case reports 下肢动脉药物洗脱支架植入术后动脉瘤变性:系统回顾和病例报告
Pub Date : 2025-07-06 DOI: 10.1016/j.avsurg.2025.100395
Angela Luongo , Nicola Cantile , Davide Turchino , Abdul Karim Markabaoui , Raffaele Serra , Umberto Marcello Bracale

Background

Paclitaxel-eluting stents (DES) are widely used in the treatment of femoropopliteal peripheral arterial disease (PAD) due to their ability to inhibit neointimal hyperplasia and reduce restenosis rates. However, recent observational data have raised concerns about delayed complications, particularly aneurysmal degeneration of the treated arterial segments.

Objectives

To systematically review the incidence, anatomical distribution, mechanisms, and clinical outcomes of aneurysmal degeneration following implantation of paclitaxel-eluting stents in lower limb arteries, define its incidence, anatomical distribution, proposed mechanisms, diagnostic criteria, and therapeutic approaches and to present a representative case requiring open surgical revision 12 months post-Eluvia implantation.

Methods

A PRISMA-compliant systematic review was performed including randomized trials, observational studies, and case reports describing aneurysmal degeneration after DES implantation. Data were extracted regarding stent type, lesion location, diagnostic methods, follow-up, and clinical outcomes. A clinical case of aneurysmal degeneration of the common femoral artery (CFA) following Eluvia implantation was integrated.

Results

Thirteen studies were included, comprising 1 randomized controlled trial, 6 observational cohorts, 1 case series, and 5 case reports. The incidence of aneurysmal degeneration ranged from 0 % to 15.7 %, with the superficial femoral artery (SFA) being the most affected site. Conservative management was common, although some cases required open surgical treatment. Our patient underwent aneurysmectomy and bypass for CFA degeneration 12 months after DES placement.

Conclusions

Aneurysmal degeneration after femoropopliteal DES implantation may be underdiagnosed and clinically relevant. Given the variability in diagnostic criteria and long-term risk, systematic surveillance and further investigation are warranted, particularly in off-label stent applications.
背景紫杉醇洗脱支架(DES)因其抑制新生内膜增生和降低再狭窄率的能力而广泛应用于股腘动脉外周动脉疾病(PAD)的治疗。然而,最近的观察数据引起了对延迟并发症的关注,特别是治疗动脉段的动脉瘤变性。目的系统回顾下肢动脉植入紫杉醇洗脱支架后动脉瘤变性的发生率、解剖分布、机制和临床结果,明确其发生率、解剖分布、可能的机制、诊断标准和治疗方法,并报告一例在植入紫杉醇洗脱支架后12个月需要开放性手术翻修的典型病例。方法采用符合prisma标准的系统评价,包括随机试验、观察性研究和描述DES植入后动脉瘤变性的病例报告。提取有关支架类型、病变位置、诊断方法、随访和临床结果的数据。本文报告1例Eluvia植入术后的股总动脉动脉瘤变性。结果纳入13项研究,包括1项随机对照试验、6项观察性队列、1项病例系列和5项病例报告。动脉瘤变性的发生率从0%到15.7%不等,其中股浅动脉(SFA)是最受影响的部位。保守治疗是常见的,尽管一些病例需要开放手术治疗。我们的患者在放置DES 12个月后接受了动脉瘤切除术和绕道治疗。结论股腘动脉内酯类药物植入后动脉瘤样变性可能存在漏诊和临床相关性。考虑到诊断标准和长期风险的可变性,系统的监测和进一步的调查是必要的,特别是在标签外支架应用中。
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引用次数: 0
期刊
Annals of vascular surgery. Brief reports and innovations
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