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Comparison Between the Protective Effect of Isoflurane and Propofol on Myocardium During Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis of Randomized Controlled Trials 异氟醚和丙泊酚对冠状动脉旁路移植术中心肌保护作用的比较:随机对照试验的系统回顾和元分析
Pub Date : 2024-04-15 DOI: 10.21470/1678-9741-2021-0424
Qi Bao, Min Lei, Dongju Xiao, Junran Xie
Objective Intravenous non-volatile anaesthetics like propofol are commonly used in cardiac surgeries across several countries. Volatile anaesthetics like isoflurane may help in protecting the myocardium and minimize ischaemia-reperfusion injury. Hence, we did this review to compare the cardioprotective effect of isoflurane and propofol among patients undergoing coronary artery bypass grafting (CABG). Methods We conducted a search in the databases Medical Literature Analysis and Retrieval System Online (or MEDLINE), Embase, PubMed Central®, ScienceDirect, Google Scholar, and Cochrane Library from inception until April 2021. We carried out a meta-analysis with random-effects model and reported pooled risk ratio (RR) or standardized mean difference (SMD) with 95% confidence interval (CI) depending on the type of outcome. Results We analysed 13 studies including 808 participants. Almost all were low-quality studies. For cardiac index, the pooled SMD was 0.14 (95% CI: -0.22 to 0.50); for cardiac troponin I, pooled SMD was 0.10 (95% CI: -0.28 to 0.48). For mortality, the RR was 3.00 (95% CI: 0.32 to 28.43); for MI, pooled RR was 1.58 (95% CI: 0.59 to 4.20); and for inotropic drug use, pooled RR was 1.04 (95% CI: 0.90 to 1.21). For length of intensive care unit stay, the pooled SMD was 0.13 (95% CI: -0.29 to 0.55), while pooled SMD for mechanical ventilation time was -0.02 (95% CI: -0.54 to 0.51). Conclusion Isoflurane did not have significant cardioprotective effect compared to propofol following CABG. Hence, the anaesthetists need to check some viable alternatives to manage these patients and reduce the rate of postoperative complications.
目的 多个国家在心脏手术中普遍使用异丙酚等静脉注射非挥发性麻醉剂。异氟醚等挥发性麻醉剂可能有助于保护心肌和减少缺血再灌注损伤。因此,我们撰写了这篇综述,以比较异氟醚和异丙酚对接受冠状动脉旁路移植术(CABG)的患者的心脏保护作用。方法 我们在医学文献分析和检索系统在线(或 MEDLINE)、Embase、PubMed Central®、ScienceDirect、Google Scholar 和 Cochrane Library 等数据库中进行了检索,检索时间从开始到 2021 年 4 月。我们采用随机效应模型进行了荟萃分析,并根据结果类型报告了汇集风险比(RR)或标准化平均差(SMD)及 95% 置信区间(CI)。结果 我们分析了包括 808 名参与者在内的 13 项研究。几乎所有研究都是低质量研究。就心脏指数而言,汇总的 SMD 为 0.14(95% CI:-0.22 至 0.50);就心肌肌钙蛋白 I 而言,汇总的 SMD 为 0.10(95% CI:-0.28 至 0.48)。死亡率的RR为3.00(95% CI:0.32至28.43);心肌梗死的汇总RR为1.58(95% CI:0.59至4.20);使用肌力药物的汇总RR为1.04(95% CI:0.90至1.21)。重症监护室住院时间的集合 SMD 为 0.13(95% CI:-0.29 至 0.55),机械通气时间的集合 SMD 为-0.02(95% CI:-0.54 至 0.51)。结论 与异丙酚相比,异氟醚在 CABG 术后没有显著的心脏保护作用。因此,麻醉师需要检查一些可行的替代方案来管理这些患者并降低术后并发症的发生率。
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引用次数: 0
The Impact of Transcatheter or Surgical Defect Closure on Self-Reported Sleep Quality in Adults with Atrial Septal Defect. 经导管或手术关闭缺陷对患有心房隔缺损的成人自我描述的睡眠质量的影响。
Pub Date : 2024-04-05 DOI: 10.21470/1678-9741-2023-0267
Mert Evlice, Sinem Berik Safçı, Emre Paçacı, Samet Ayna, Sinan Cerşit, Lütfi Öcal, Mustafa Ozan Gürsoy, Abdullah Yıldırım, İbrahim Halil Kurt
Sleep quality in those with cardiovascular disease is significantly lower than in the general population. This study aimed to explore the effect of transcatheter or surgical closure of atrial septal defect (ASD) on sleep quality.
心血管疾病患者的睡眠质量明显低于普通人群。本研究旨在探讨经导管或手术关闭房间隔缺损(ASD)对睡眠质量的影响。
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引用次数: 0
Association Between Body Mass Index, Obesity, and Clinical Outcomes Following Coronary Artery Bypass Grafting in Brazil: An Analysis of One Year of Follow-up of BYPASS Registry Patients. 巴西冠状动脉旁路移植术后体重指数、肥胖与临床结果之间的关系:对 BYPASS 注册患者一年随访的分析。
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0133
Rodrigo Santin Ramos, Isadora Salvador Rocco, Marcela Viceconte, José Amalth do Espírito Santo, Otavio Berwanger, Renato Hideo Nakagawa Santos, Renato Abdala Karam Kalil, Fabio B Jatene, Alexandre Biasi Cavalcanti, Alexandre Cabral Zilli, Walace de Souza Pimentel, Nelson Américo Hossne, João Nelson Rodrigues Branco, Renata Trimer, Paulo Roberto Barbora Evora, Walter J Gomes, Solange Guizilin
To investigate the association between body mass index (BMI), obesity, clinical outcomes, and mortality following coronary artery bypass grafting (CABG) in Brazil using a large sample with one year of follow-up from the Brazilian Registry of Cardiovascular Surgeries in Adults (or BYPASS) Registry database.
目的:利用巴西成人心血管手术登记(或 BYPASS)登记数据库中随访一年的大样本,研究巴西冠状动脉旁路移植术(CABG)术后体重指数(BMI)、肥胖、临床结果和死亡率之间的关系。
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引用次数: 0
Hemostasis Using Prothrombin Complex Concentrate in Patients Undergoing Cardiac Surgery: Systematic Review with Meta-Analysis. 心脏手术患者使用凝血酶原复合物浓缩物止血:系统回顾与 Meta 分析。
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0076
Jun-Ping Li, Yan Li, Bing Li, Chang-He Bian, Feng Zhao
The purpose of present study was to comprehensívely explore the efficacy and safety of prothrombín complex concentrate (PCC) to treat massíve bleedíng in patíents undergoing cardiac surgery.
本研究旨在全面探讨凝血酶原复合物浓缩物(PCC)治疗心脏手术患者大量出血的有效性和安全性。
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引用次数: 0
Thinking Outside the Box: The Interventional Surgeon. 跳出框框思考:介入外科医生。
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0207
Adnaldo da Silveira Maia, Karlos Jennysson Sousa Soares, Pedro Esteban Ulloa Alvarado, Francisco Victor Alves da Silva, Dayara Hoffmann Mayer, Mauro Henrique Batista Camacho, José Honório de Almeida Palma da Fonseca
Advances in treatment of structural heart disease have been disruptive to cardiovascular surgery, and there have been discussions about how to incorporate these technologies into the surgeons' therapeutic arsenal. Transcatheter procedures, complex redo interventions, and endovascular aortic approaches are already practiced by cardiovascular surgeons in Brazil. The expansion of these techniques, coupled with recent changes in the country's medical residency program in cardiovascular surgery, has led to an urgent need to acquire catheter-based skills. In this article, we discuss these aspects in the light of the reality of cardiovascular surgery training in Brazil.
结构性心脏病治疗的进步对心血管外科具有颠覆性的影响,人们一直在讨论如何将这些技术纳入外科医生的治疗武器库。在巴西,心血管外科医生已经开展了经导管手术、复杂的重做介入手术和血管内主动脉手术。这些技术的扩展,加上巴西心血管外科住院医师培训计划的最新变化,导致人们迫切需要掌握以导管为基础的技能。在本文中,我们将结合巴西心血管外科培训的实际情况对这些方面进行讨论。
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引用次数: 0
Intravital Microscopy Evidence That Methylene Blue Should Be a Vasopressor-Sparing Agent in Sepsis Vasoplegia. 肉眼显微镜证据表明亚甲蓝应成为败血症脉搏骤停的血管加压剂。
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0066
Fabiola Leslie Antunes Cardoso Mestriner, Pedro Brüch Dantas, Jéssyca Michelon Barbosa, Paulo Roberto B Evora, Christiane Becari
Microvasculature failure is expected in sepsis and at higher amine concentrations. Therefore, special attention focused individually on microcirculation is needed. Here, we present that methylene blue can prevent leukocytes from adhering to the endothelium in a rat model of lipopolysaccharide-induced endotoxemia. As hypothesis evidence, an intravital microscopy image is presented.
在败血症和胺浓度较高的情况下,微血管会出现衰竭。因此,需要特别关注微循环。在此,我们介绍了亚甲基蓝在脂多糖诱导的内毒素血症大鼠模型中可阻止白细胞粘附在内皮上。作为假说证据,我们展示了一张体视显微镜图像。
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引用次数: 0
Reflections Upon 55 Years of the First Human Heart Transplant in Brazil. 巴西首例人类心脏移植手术 55 周年的反思。
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0208
Noedir Antonio Groppo Stolf
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引用次数: 0
Early Outcomes of Minimally Invasive Right Anterior Thoracotomy vs. Median Full Sternotomy in Isolated Aortic Valve Replacement: A Propensity Score Analysis. 微创右胸前切口术与中位全腔镜主动脉瓣置换术的早期疗效对比:倾向评分分析
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0108
Anas O Kh Abubokha, Rui Li, Chen-He Li, Ahmad M Zalloom, Xiang Wei
This study aimed to compare the early postoperative outcomes of right anterior thoracotomy minimally invasive aortic valve replacement (RAT-MIAVR) surgery with those of median full sternotomy aortic valve replacement (MFS-AVR) approach with the goal of identifying potential benefits or drawbacks of each technique.
本研究旨在比较右前胸廓切开微创主动脉瓣置换术(RAT-MIAVR)与胸骨正中全切主动脉瓣置换术(MFS-AVR)的术后早期疗效,目的是找出两种技术的潜在优点或缺点。
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引用次数: 0
Tricuspid Apparatus Detachment for Exposure of Ventricular Septal Defect: A Justified Approach? 三尖瓣分离术用于暴露室间隔缺损:一种合理的方法?
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0202
Rahul Bhushan, Vijay Grover
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引用次数: 0
Incremental Ramp Load Protocol to Assess Inspiratory Muscle Endurance in Healthy Individuals: Comparison with Incremental Step Loading Protocol. 用于评估健康人吸气肌肉耐力的增量斜坡负荷方案:与增量阶梯加载方案的比较。
Pub Date : 2024-04-03 DOI: 10.21470/1678-9741-2023-0231
Guilherme de Souza Areias, Alexandre Fenley, Luan Rodrigues Santiago, Alessandra Choqueta de Toledo Arruda, Rodrigo Boemo Jaenisch, Solange Guizilini, Michel Silva Reis
Protocols for obtaíníng the maxímum threshold pressure have been applied wíth límited precision to evaluate ínspiratory muscle endurance. In thís sense, new protocols are needed to allow more relíable measurements. The purpose of the present study was to compare a new incremental ramp load protocol for the evaluation of ínspíratory muscle endurance wíth the most used protocol in healthy indíviduals.
获取最大阈值压力的方法已被用于评估呼吸肌耐力,但精确度有限。从这个意义上讲,我们需要新的方案来进行更可靠的测量。本研究的目的是将用于评估呼吸肌耐力的新增量斜坡负荷方案与在健康人中最常用的方案进行比较。
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Brazilian journal of cardiovascular surgery
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