Pub Date : 1994-01-01DOI: 10.1007/978-3-642-85159-9_25
H. Ulmer, D. Hossfeld
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Pub Date : 1980-08-01DOI: 10.1001/ARCHDERM.1980.01640320035009
F. Malkinson
It has been clearly demonstrated that temperature increases of only a few degrees greater than normal induce profound cellular changes and even cell death. The first beneficial effects of these phenomena were recorded more than a century ago by Busch, 1 who observed the disappearance of a sarcoma after high fever in a patient with erysipelas. In 1893, Coley 2 noted the same clinical event and then deliberately induced erysipelas as a form of treatment for patients with malignancies. He described disease-free survival from one to seven years in ten of 34 patients with inoperable carcinomas or sarcomas, but was undecided whether to attribute these remissions to the fever induced or to some effect of bacterial toxins. Later, the use of local heat and of pyrogenic bacterial toxins was also evaluated in patients with tumors. Occasional successes then prompted the induction of fever therapy for infectious diseases (syphilis and gonorrhea)
{"title":"The Heat's On","authors":"F. Malkinson","doi":"10.1001/ARCHDERM.1980.01640320035009","DOIUrl":"https://doi.org/10.1001/ARCHDERM.1980.01640320035009","url":null,"abstract":"It has been clearly demonstrated that temperature increases of only a few degrees greater than normal induce profound cellular changes and even cell death. The first beneficial effects of these phenomena were recorded more than a century ago by Busch, 1 who observed the disappearance of a sarcoma after high fever in a patient with erysipelas. In 1893, Coley 2 noted the same clinical event and then deliberately induced erysipelas as a form of treatment for patients with malignancies. He described disease-free survival from one to seven years in ten of 34 patients with inoperable carcinomas or sarcomas, but was undecided whether to attribute these remissions to the fever induced or to some effect of bacterial toxins. Later, the use of local heat and of pyrogenic bacterial toxins was also evaluated in patients with tumors. Occasional successes then prompted the induction of fever therapy for infectious diseases (syphilis and gonorrhea)","PeriodicalId":72489,"journal":{"name":"California medicine","volume":"16 2","pages":"885-887"},"PeriodicalIF":0.0,"publicationDate":"1980-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/ARCHDERM.1980.01640320035009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50605925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The CMA as a new kind of organizational instrument.","authors":"M S Watts","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72489,"journal":{"name":"California medicine","volume":"119 6","pages":"3-17"},"PeriodicalIF":0.0,"publicationDate":"1973-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1455368/pdf/califmed00006-0025.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15855227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new journal and an energetic medical association.","authors":"E K Rose","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":72489,"journal":{"name":"California medicine","volume":"119 6","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"1973-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1455359/pdf/califmed00006-0023.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15855226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1973-12-01DOI: 10.7326/0003-4819-79-2-329_5
Jr. Edward P. Passaro
What do you do to start reading readings in modern surgery ? Searching the book that you love to read first or find an interesting book that will make you want to read? Everybody has difference with their reason of reading a book. Actuary, reading habit must be from earlier. Many people may be love to read, but not a book. It's not fault. Someone will be bored to open the thick book with small words to read. In more, this is the real condition. So do happen probably with this readings in modern surgery .
{"title":"READINGS IN MODERN SURGERY.","authors":"Jr. Edward P. Passaro","doi":"10.7326/0003-4819-79-2-329_5","DOIUrl":"https://doi.org/10.7326/0003-4819-79-2-329_5","url":null,"abstract":"What do you do to start reading readings in modern surgery ? Searching the book that you love to read first or find an interesting book that will make you want to read? Everybody has difference with their reason of reading a book. Actuary, reading habit must be from earlier. Many people may be love to read, but not a book. It's not fault. Someone will be bored to open the thick book with small words to read. In more, this is the real condition. So do happen probably with this readings in modern surgery .","PeriodicalId":72489,"journal":{"name":"California medicine","volume":"119 1","pages":"71-71"},"PeriodicalIF":0.0,"publicationDate":"1973-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71184782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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