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Cancer health disparities最新文献

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The System is Unfair 制度不公平
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_9
Wisler Saint-Vil
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引用次数: 0
Jane in Room 18 18号房的简
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_33
Michael D. Paronish
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引用次数: 0
Am I a Strong Person? 我是一个坚强的人吗?
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_34
David Sperling
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引用次数: 1
The Irritable Uterus 易激子宫
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_10
R. Fischbein
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引用次数: 0
Bakit? (Why?)
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_53
Mariquita Tolentino-Belen
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引用次数: 0
Everyone Called Him Crazy 大家都说他疯了
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_20
Veronica Cheung
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引用次数: 0
How Can We Care for Everyone? 我们如何关心每个人?
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_5
Christina Antenucci
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引用次数: 0
What Kind of System Is This? 这是一个什么样的系统?
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_49
Betsy Ekey
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引用次数: 0
Breast Cancer Incidence and Mortality by Molecular Subtype: Statewide Age and Racial/Ethnic Disparities in New Jersey. 按分子亚型划分的乳腺癌发病率和死亡率:新泽西州全州年龄和种族/民族差异
Pub Date : 2019-01-01 Epub Date: 2019-08-19 DOI: 10.9777/chd.2019.1012
Aishwarya Kulkarni, Antoinette M Stroup, Lisa E Paddock, Stephanie M Hill, Jesse J Plascak, Adana A M Llanos

The objective of this study was to assess breast cancer incidence and mortality rates by molecular subtype for cases diagnosed in New Jersey. Data on all primary, histologically confirmed, invasive breast cancers diagnosed among women between January 1, 2008 and December 31, 2013 were retrieved from the New Jersey State Cancer Registry. Age-adjusted incidence rates were calculated for each subtype, by ageandrace/ethnicity. Logistic regression models, Cox proportional hazards models, and Kaplan Meier curves were used to describe the relative risks for breast cancer incidence, mortality, and survival, respectively. In this population-based sample of 32,770 breast cancer cases, non-Hispanic Blacks (NHBs) had the highest triple-negative breast cancer (TNBC) incidence rate (17.8 per 100,000, 95% CI 16.5-19.2) compared to other races/ethnicities. NHBs had also higher odds of TNBC (OR 2.1, 95% CI 1.95-2.36) and higher hazards of death when diagnosed with TNBC (HR 1.28, 95% CI 1.05-1.56), luminal A (HR 1.64, 95% CI 1.41-1.91), or luminal B (HR 1.54, 95% CI 1.10-2.15) than non-Hispanic Whites (NHWs). Younger women (20-39 years) had higher odds of TNBC (OR 1.77, 95% CI 1.54-2.02) and luminal B (OR 1.56, 95% CI 1.35-1.80) compared to women 50-64 years; minority women had higher odds of non-luminal HER2-expressing and lower odds of luminal A than NHWs. TNBC was associated with the poorest survival rates. These findings highlight a need for enhanced screening to promote earlier diagnosis and improve breast cancer outcomes, particularly in minorities and younger women, which will be essential for achieving health equity.

本研究的目的是评估新泽西州诊断病例的分子亚型乳腺癌发病率和死亡率。2008年1月1日至2013年12月31日期间,所有在女性中诊断出的原发性、组织学证实的浸润性乳腺癌的数据均来自新泽西州癌症登记处。按年龄和种族/民族计算每个亚型的年龄调整发病率。分别采用Logistic回归模型、Cox比例风险模型和Kaplan Meier曲线来描述乳腺癌发病率、死亡率和生存率的相对风险。在这个以人群为基础的32,770例乳腺癌病例样本中,与其他种族/民族相比,非西班牙裔黑人(NHBs)的三阴性乳腺癌(TNBC)发病率最高(17.8 / 100,000,95% CI 16.5-19.2)。与非西班牙裔白人(NHWs)相比,NHBs患TNBC的几率更高(OR 2.1, 95% CI 1.95-2.36),被诊断为TNBC时的死亡风险更高(HR 1.28, 95% CI 1.05-1.56)、luminal A (HR 1.64, 95% CI 1.41-1.91)或luminal B (HR 1.54, 95% CI 1.10-2.15)。与50-64岁的女性相比,年轻女性(20-39岁)患TNBC (OR 1.77, 95% CI 1.54-2.02)和luminal B (OR 1.56, 95% CI 1.35-1.80)的几率更高;少数族裔女性非腔内表达her2的几率高于非裔女性,而腔内表达A的几率低于非裔女性。TNBC与最低生存率相关。这些发现突出表明,需要加强筛查,以促进早期诊断和改善乳腺癌结果,特别是在少数民族和年轻妇女中,这对实现卫生公平至关重要。
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引用次数: 0
Time to Leave 是时候离开了
Pub Date : 2019-01-01 DOI: 10.1007/978-3-030-12771-8_4
I. Adebambo
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引用次数: 0
期刊
Cancer health disparities
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