Dermatologie (Heidelberg, Germany)最新文献

Chronic inflammatory skin diseases such as psoriasis, acne, or atopic dermatitis are frequently associated with psychological comorbidities including depression, anxiety disorders, or sleep disturbances. These burdens are clinically relevant and have a significant impact on both the course of the disease and patients' quality of life. However, access to psychotherapeutic care is often hindered by long waiting times and a lack of established structures within standard dermatological care. The integration of digital interventions therefore appears both important and promising. The aim of this work is to provide a structured overview of currently available digital health applications (DiGAs) that are relevant for managing psychological and behavioral concomitant issues in dermatology, and to critically appraise their opportunities and challenges in clinical use. The data source was the official DiGA directory maintained by BfArM (cut-off: May 2025). Following a complete screening, 31 applications were identified based on predefined criteria: patient-guided, and theoretically grounded interventions targeting depression, anxiety, sleep, stress/burnout, substance use, eating disorders/obesity, or pain. These were categorized by indication (ICD-10), therapeutic approach, platform, intended duration of use, and availability of contact/support elements. Opportunities for implementation and integration into routine dermatological care, as well as remaining challenges, are discussed.

Complications of tattooing occur in 2% of cases and include foreign body granulomas, for which treatment options are limited and often ineffective. Allopurinol, a xanthine oxidase inhibitor, is used to treat granulomatous reactions, but often leads to systemic side effects. Two recent case reports have described topical application as better tolerated. Herein, we report a patient who developed a granulomatous reaction to permanent eyebrow make-up, for which topical allopurinol achieved a satisfactory result.

Plastic reconstructions in the head and neck region are common procedures in dermatology. However, the theoretical principles underlying these, which are the basis for successful surgery, are rarely taught in dermatology training. This summary of the basic theoretical concepts for plastic reconstructive surgery is intended to close this gap. Over the past 100 years, repeated attempts have been made to improve the technique of plastic reconstructive surgery and to make it more understandable though different concepts. This includes knowledge of the timing of reconstruction, the trophism of the different flaps, the incision lines, the esthetic subunits of the face and flap classification based on the ladder of plastic reconstruction.

A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment's response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.

Since 2003, the Bamberg Recommendation has provided a scientifically sound basis for assessing dermatological expert opinion reports on occupational skin diseases. The revised version of the Bamberg Recommendation, published on 9 October 2025, explains the legal basis for assessing occupational skin diseases and outlines a structured assessment process with the aim of ensuring equal treatment of those affected and transparency of decisions. It thus provides dermatologists acting as assessors with important support in their role as neutral experts.

Perioperative use of anticoagulation in the context of skin surgery can be difficult. The different forms of anticoagulation act on different points in the coagulation cascade; therefore, different perioperative difficulties exist, which have to be considered preoperatively. The current guidelines "Umgang mit Antikoagulanzien und Thrombozytenaggregationshemmern bei Operationen an der Haut" provides assistance in the decision-making for the practitioner. Individual factors that influence bleeding or coagulation should be considered and evaluated preoperatively. This article gives an overview of the current guidelines and factors that must be considered preoperatively.