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Immuno-oncology technology最新文献

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114P Exploring the role of FES kinase in natural killer cells to enhance immunotherapy 114P探讨FES激酶在自然杀伤细胞增强免疫治疗中的作用
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101199
A.A. Varty-Higgs , J. Simonetti , B.J. Laight , P.A. Greer
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引用次数: 0
105P Engineering primary CD8+ T cells with a novel PD-L1-specific TCR 105P工程原代CD8+ T细胞与新的pd - l1特异性TCR
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101190
E.B. Jacobsen , T.H. Lisle , S.M. Ahmad , E. Martinenaite , Ö. Met , R. Bak , M.H. Andersen
{"title":"105P Engineering primary CD8+ T cells with a novel PD-L1-specific TCR","authors":"E.B. Jacobsen , T.H. Lisle , S.M. Ahmad , E. Martinenaite , Ö. Met , R. Bak , M.H. Andersen","doi":"10.1016/j.iotech.2025.101190","DOIUrl":"10.1016/j.iotech.2025.101190","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101190"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
106P Tumor-infiltrating lymphocytes (TILs) expanded from soft tissue sarcoma show promising preclinical reactivity against autologous tumor cells 从软组织肉瘤中扩增的肿瘤浸润淋巴细胞（til）对自体肿瘤细胞具有良好的临床前反应性
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101191
W.S. Tak , E. Simonetti , L. Tas , M. Sokolov , E. Vedder , M. van Zon , W. Van Houdt , J.B.A.G. Haanen , I. Jedema
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引用次数: 0
57P Immune competence as a biomarker of response to immune checkpoint inhibition in non-small cell lung cancer 免疫能力作为非小细胞肺癌免疫检查点抑制应答的生物标志物
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101140
T. Roberts , S. Haider , T. Adam , A. James , M. Hong , H. McGuire , B. Fazekas , O. Vittorio , T. Becker , T. Shai-Hee , V.J. Bray , K. Keat , W. Chua
{"title":"57P Immune competence as a biomarker of response to immune checkpoint inhibition in non-small cell lung cancer","authors":"T. Roberts , S. Haider , T. Adam , A. James , M. Hong , H. McGuire , B. Fazekas , O. Vittorio , T. Becker , T. Shai-Hee , V.J. Bray , K. Keat , W. Chua","doi":"10.1016/j.iotech.2025.101140","DOIUrl":"10.1016/j.iotech.2025.101140","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101140"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145836756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
8P The role of glycemia in prognostic implications for non-diabetic melanoma patients treated with immunotherapy 血糖在非糖尿病性黑色素瘤患者免疫治疗预后中的作用
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101093
D. Mallardo , A. Minopoli , M. Ingenito , M. Ottaviano , L. Festino , L. Di Capua , V. Vanella , C. Trojaniello , M.G. Vitale , M. Bailey , F. Sparano , B.A. Facchini , A. White , C. Caracò , E. Simeone , A. Cesano , A. Budillon , E. Cavalcanti , P.A. Ascierto
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引用次数: 0
86P TR-TIL platform: Antigen-agnostic pan-cancer identification of polyclonal tumor-reactive CD4+ and CD8+ TILs for TCR discovery 86P TR-TIL平台：用于发现TCR的多克隆肿瘤反应性CD4+和CD8+ til的抗原不可知泛癌鉴定
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101171
A. Draghi , C.A. Chamberlain , A. Weiss , S. Khan , K. Harbst , E. Dionisio , A. Kurtz , Y. Garitaonaindía Díaz , A.W.P. Jensen , A. Sandnes , M. Presti , J.V. Schou , G. Jönsson , I.M. Svane , M. Donia
{"title":"86P TR-TIL platform: Antigen-agnostic pan-cancer identification of polyclonal tumor-reactive CD4+ and CD8+ TILs for TCR discovery","authors":"A. Draghi , C.A. Chamberlain , A. Weiss , S. Khan , K. Harbst , E. Dionisio , A. Kurtz , Y. Garitaonaindía Díaz , A.W.P. Jensen , A. Sandnes , M. Presti , J.V. Schou , G. Jönsson , I.M. Svane , M. Donia","doi":"10.1016/j.iotech.2025.101171","DOIUrl":"10.1016/j.iotech.2025.101171","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101171"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
90P Optimising tumour-infiltrating lymphocyte expansion and tumour reactivity with a cocktail of IL-2 family cytokines in head & neck squamous cell carcinoma IL-2家族细胞因子对头颈部鳞状细胞癌浸润淋巴细胞扩张和肿瘤反应性的影响
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101175
S.Y.N. Wong , H.S. Quah , L. Suteja , H.S. Leong , B. Hariraman , D.S.W. Tan , N.G. Iyer
{"title":"90P Optimising tumour-infiltrating lymphocyte expansion and tumour reactivity with a cocktail of IL-2 family cytokines in head & neck squamous cell carcinoma","authors":"S.Y.N. Wong , H.S. Quah , L. Suteja , H.S. Leong , B. Hariraman , D.S.W. Tan , N.G. Iyer","doi":"10.1016/j.iotech.2025.101175","DOIUrl":"10.1016/j.iotech.2025.101175","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101175"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
40P Ectonucleotide pyrophosphate/phosphodiesterase 3 (ENPP3) expression selects distinct transcriptional clusters in metastatic renal cell carcinoma (mRCC) 40P外核苷酸焦磷酸/磷酸二酯酶3 （ENPP3）在转移性肾癌（mRCC）中的表达
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101123
V. Abreu de Goes , N.J. Salgia , Y.J. Li , K. Shah , M. Zugman , S. Jaime-Casas , B. Mercier , D. Castro , R. Barragan-Carrillo , X. Li , H. Ebrahimi , R. Agarwal , J. Hsu , A. Chehrazi-Raffle , S.K. Pal
{"title":"40P Ectonucleotide pyrophosphate/phosphodiesterase 3 (ENPP3) expression selects distinct transcriptional clusters in metastatic renal cell carcinoma (mRCC)","authors":"V. Abreu de Goes , N.J. Salgia , Y.J. Li , K. Shah , M. Zugman , S. Jaime-Casas , B. Mercier , D. Castro , R. Barragan-Carrillo , X. Li , H. Ebrahimi , R. Agarwal , J. Hsu , A. Chehrazi-Raffle , S.K. Pal","doi":"10.1016/j.iotech.2025.101123","DOIUrl":"10.1016/j.iotech.2025.101123","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101123"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
31P NMR-based plasma profiling reveals metabolic reprogramming in prostate cancer progression 基于31P核磁共振的血浆分析揭示前列腺癌进展中的代谢重编程
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101114
S.S. Bahukhandi , R. Kumar , S. Kaushal , M. Khan , V. Kumar
{"title":"31P NMR-based plasma profiling reveals metabolic reprogramming in prostate cancer progression","authors":"S.S. Bahukhandi , R. Kumar , S. Kaushal , M. Khan , V. Kumar","doi":"10.1016/j.iotech.2025.101114","DOIUrl":"10.1016/j.iotech.2025.101114","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101114"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
108P FIRST CAR T: Leveraging P4HA1 biology with triple gene-edited CAR T cells for persistence and durable responses in solid tumors 108P FIRST CAR - T：利用P4HA1生物学与三基因编辑的CAR - T细胞在实体肿瘤中的持久性和持久性反应
Immuno-oncology technology
Pub Date : 2025-12-01 DOI: 10.1016/j.iotech.2025.101193
L-T. Ong, Q. Yu
{"title":"108P FIRST CAR T: Leveraging P4HA1 biology with triple gene-edited CAR T cells for persistence and durable responses in solid tumors","authors":"L-T. Ong, Q. Yu","doi":"10.1016/j.iotech.2025.101193","DOIUrl":"10.1016/j.iotech.2025.101193","url":null,"abstract":"","PeriodicalId":73352,"journal":{"name":"Immuno-oncology technology","volume":"28 ","pages":"Article 101193"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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