Joint diseases and related surgery最新文献

Objectives: In this study, we present our extensive case series on hamatometacarpal fracture-dislocations treated with open reduction and internal fixation and share our treatment strategies and outcomes.

Patients and methods: Between March 2014 and November 2022, a total of 17 male patients (mean age: 28.6±7.9 years; range, 18 to 49 years) with isolated hamate fracture or a fracture involving the base of the fourth and/or fifth metacarpals who underwent surgery and were followed for a minimum duration of 12 months were retrospectively analyzed. Mechanism of injury, type of hamate fracture, presence of associated metacarpal fracture-dislocations, demographic data, time to surgery, postoperative duration of immobilization and complications were noted. Functional assessment was performed using Disabilities of the Arm, Shoulder, and Hand (DASH) scoring and grip strength was evaluated using a hand dynamometer.

Results: The mean follow-up was 5.8±2.2 (range, 2 to 8) years. All patients were male, with fractures on the dominant side, and the primary mechanism of injury was punching a hard surface. Surgical fixation primarily involved a single screw, with Kirschner wires used for metacarpal stabilization. The mean time to return to work was 61±22 (range, 35 to 90) days. The mean grip strength of the injured and uninjured side was 40.5±3.6 kg and 42.1±3.5 kg, respectively (p=0.415). The mean DASH score at the final follow-up was 5.6±4.8. All patients achieved clinical union, with no malunions, and full range of motion was restored. Two cases of ulnar nerve neuropraxia fully resolved.

Conclusion: The surgical treatment of coronal plane hamate fractures associated with the fourth and fifth metacarpal base fracture-dislocations can provide good functional recovery in these complex fractures.

Objectives: The study aimed to evaluate the hidden blood loss (HBL) and its possible risk factors in patients with lumbar disc herniation undergoing percutaneous endoscopic lumbar discectomy (PELD) via posterolateral approach.

Patients and methods: The clinical data of 170 lumbar disc herniation patients (101 males, 69 females; mean age: 57.7±18.0 years; range, 19 to 87 years) treated with PELD via posterolateral approach between January 2021 and January 2023 were retrospectively analyzed. Demographic characteristics, laboratory data, and surgery-related clinical data of the patients were collected, including age, sex, height, weight, body mass index, albumin, blood glucose, hemoglobin (Hb), hematocrit (Hct), American Society of Anesthesiologists (ASA) score, surgical time, number of puncture, and the need for foramenoplasty. Hidden blood loss was calculated, and multiple linear regression analysis was performed to identify risk factors.

Results: The mean Hb in patients with preoperative anemia was 115.8±8.6 g/L. The mean postoperative Hb loss and Hct loss were 7.0±4.5 g/L and 0.02±0.01%, respectively. The mean number of punctures (1-3 punctures vs. >3 punctures) was 2.4±0.7 and 4.6±0.6, respectively. Satisfactory localization was achieved within three punctures in nearly 60% of the patients. More than half (55.3%) of the patients underwent foraminoplasty. The mean surgical time was 110.9±32.0 min. The mean HBL was 178.4±66.5 mL. The mean follow-up time was 6.9±2.2 months. When comparing the preoperative and postoperative incidence of anemia, we found that the incidence of anemia was significantly associated with HBL (p<0.001). Multiple linear regression analysis showed that HBL was positively correlated with the number of punctures, foraminoplasty, and surgical time.

Conclusion: Our results suggest that the number of punctures, foraminoplasty, and surgical time are independent risk factors for HBL after PELD via posterolateral approach. Therefore, HBL should not be ignored in patients with these risk factors to ensure patients' safety in the perioperative period.

Objectives: This study aims to investigate quantitatively the protective effect of a 1.6-mm or a 2.5-mm Kirschner wire (K-wire) on the medial hinge at different gap distances through finite element analysis (FEA) and to establish whether using a 2.5-mm K-wire can offer benefits compared to a 1.6-mm in preventing medial hinge fractures.

Materials and methods: Between June 2024 and July 2024, three different models simulating a lateral opening wedge (LOW) osteotomy of the distal femur were created from a femoral computed tomography (CT) scan of a 36-year-old male patient: no K-wire (Model I), 1.6-mm K-wire (Model II), and 2.5-mm K-wire (Model III). Finite element analysis was performed to simulate 7- to 13-mm gaps at the osteotomy site. Loads, principal stress, strain, and equivalent stress were analyzed around the medial hinge.

Results: Model I required 123.0±5.2 N, Model II required 181.7±12.2 N, and Model III required 228.7±13.6 N (p<0.001). Cracked shell elements were the lowest in Model II and the highest in Model I. While the average equivalent/yield stress ratio was not significantly lower in Model II compared to Model III (87.0±10.9% vs. 92.7±12.1%), the maximum equivalent/yield stress ratio values in Model II were significantly lower than both Model I and Model III (1206.2±138.3% vs. 1836.2±165.4% and 1689.1±404.0%, respectively), suggesting a superior dispersion of forces.

Conclusion: Using a 1.6-mm K-wire during LOW osteotomy of the distal femur provides a balance between structural reinforcement and stress distribution, significantly improving stability and reducing the risk of medial hinge fractures compared to a 2.5-mm K-wire or no K-wire. The 1.6-mm K-wire optimizes stress dispersion, making it the preferred choice for surgical planning in lateral opening wedge distal femoral osteotomy.

Objectives: This study aimed to evaluate the impact of integrating obstetric parameters into the Fracture Risk Assessment Tool (FRAX) on the precision of risk assessment.

Patients and methods: In this retrospective study, patients who experienced postmenopausal fragility fractures of the distal radius, proximal femur, or lumbar vertebrae between January 1, 2021, and December 31, 2023, were included. Obstetric histories, along with standard FRAX parameters, were obtained by phone interviews. Based on the FRAX major osteoporotic fracture risk score calculated without bone mineral density, patients were classified into high-, intermediate-, and low-risk group categories. Differences in age at menarche, age at menopause, lactation duration, gravidity, and parity were analyzed across risk categories.

Results: A total of 328 patients (mean age: 64.5±5.8 years; range, 55 to 75 years) were included. The mean FRAX score was 16±8.8 (range, 3 to 58), and 85, 191, and 52 patients were classified as high-, intermediate-, and low-risk, respectively. A positive correlation was observed between FRAX scores and both later age at menarche and earlier menopause (p<0.001 and p=0.008, respectively). The mean age at menopause was significantly different between the high- and low-risk groups (46.4 vs. 49.3 years, p=0.016). The intermediate-risk group was also evaluated, showing no significant differences in obstetric parameters compared to the low-risk group (p>0.05).

Conclusion: Although late menarche is not explicitly included in FRAX, its association with higher fracture risk was evident. The established influence of early menopause on FRAX scores supports its role in fracture risk estimation. However, the inclusion of additional obstetric parameters did not enhance the predictive accuracy of FRAX in this cohort.

Objectives: This study aimed to evaluate the rates and risk factors associated with revision amputation following ischemic lower major limb amputations, focusing on cases related to peripheral arterial disease.

Patients and methods: This retrospective study included 253 patients (174 males, 79 females; mean age: 73.1±12.2 years; range, 44 to 99 years) who underwent ischemic foot amputation between December 2012 and December 2022. Eligible patients were over 18 years old and had major lower extremity amputations due to peripheral arterial disease or chronic arterial occlusion. Exclusions were made for amputations due to diabetic foot conditions, trauma, tumors, or osteomyelitis and minor lower extremity amputations.

Results: Above-knee amputations were the most common type of amputation, accounting for 56.5% (n=143) of cases. Revision amputations occurred in 27.3% (n=69) of patients, with significantly higher rates in those with open wounds at first admission (chi-square [χ² ]=9.81, p=0.002). Patients with occlusion at the popliteal artery level had a higher rate of revision amputation following below-knee amputation (p=0.034). Each additional year of age decreased the likelihood of revision amputation by 2.3% (p=0.049). Vacuum-assisted closure therapy was associated with higher revision rates (χ² =22.71, p<0.001). Patients who developed infections (n=40) had a significantly higher rate of revision amputations (n=26, p<0.001). Elevated preoperative C-reactive protein levels were also correlated with an increased risk of revision (p=0.006).

Conclusion: Patients with ischemic lower limb amputations, particularly those presenting with open wounds, are at higher risk for revision amputation. Elevated preoperative C-reactive protein levels, infections, age, and the initial level of amputation significantly impact the likelihood of reamputation.

Pregnancy and lactation significantly alter bone homeostasis, potentially leading to impaired bone quality and mineralization due to the increased metabolic demands of the developing offspring. While most women with osteopenia during these periods experience a return to baseline bone density after weaning, some may remain at risk for fractures, particularly in cancellous bone. There are inconsistencies in current reports on fracture risk and appropriate treatment strategies. In this review, we discuss the existing evidence on the diagnosis, clinical presentation, and approaches for preventing and managing bone fragility in this unique population.

Objectives: The aim of this study was to assess the effect of Naturagen® 4 Joint product, containing type 1, 2, and 3 collagen, on pain associated with osteoarthritis (OA) and to evaluate its effects on quality of life and physical functioning.

Patients and methods: This double-blind, randomized, placebo-controlled clinical study included a total of 31 patients (8 males, 23 females; mean age: 53.5±9.1 years; range, 35 to 65 years) with Grade 2-3 OA according to the Kellgren-Lawrence (KL) classification system between June 2023 and November 2023. The patients were divided into two groups: a collagen group (n=16) and a placebo group (n=15). The Visual Analog Scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Knee Injury and Osteoarthritis Outcome Score (KOOS-PS), Oxford Knee Score (OKS), Tampa Scale for Kinesiophobia (TSK), Short Form Health Survey (SF-12), Foot Function Index (FFI), Timed Up and Go (TUG), 6-Min Walking Test (6MWT), Five Repetition Sit to Stand Test (5STS), Stair Climbing Test (SCT), and Berg Balance Scale (BBS) were used. All tests were performed before and after eight weeks of collagen supplementation.

Results: Eight weeks of collagen supplementation yielded notable enhancements across all osteoarthritis-related pain and quality of life scales evaluated, including VAS, WOMAC, KOOS-PS, OKS, TSK, SF-12, and FFI scores (p<0.05). In functional evaluations, there were significant positive effects of collagen use in BBS and 6MWT results (p<0.05). In TUG, 5STS, and SCT tests, no significant difference was found between the groups (p>0.05).

Conclusion: Our study results suggest that the eight-week collagen-based supplement exerts a favorable effect on pain and quality of life levels, as well as some functional test results.

Objectives: This study aimed to analyze the effects of posteriorstabilized (PS) and cruciate-retaining (CR) total knee arthroplasty (TKA) on early postoperative three-dimensional (3D) dynamic and kinematic characteristics in patients with unilateral knee osteoarthritis (OA).

Patients and methods: A retrospective analysis of prospectively collected data from 90 patients with unilateral TKA between February 2021 and September 2021 was conducted using a 3D kinematic analysis system before and six months after TKA. This patient group included 57 patients (10 males, 47 females; mean age: 69.5±7.5 years; range, 53 to 85 years) who underwent PS TKA and 33 patients (11 males, 22 females; mean age: 67.9±8.8 years; range, 45 to 86 years) who underwent CR TKA. The kinematic characteristics and clinical results of the two groups were compared. Clinical evaluation included the Hospital for Special Surgery knee score and range of motion (ROM). Twenty-eight healthy controls (9 males, 19 females; mean age: 64.5±2.9 years; range, 61 to 75 years) without knee OA matched for age, weight, height, and body mass index were recruited. The kinematic characteristics of the healthy control group were also evaluated.

Results: The PS group exhibited significant changes in basic gait parameters after TKA, including cadence (p=0.046), stride time (p=0.011), opposite foot off (p<0.001), opposite foot contact (p=0.038), step time (p=0.005), double support period (p<0.001), and foot off (p=0.004). No significant differences were observed in the kinematic parameters before and after TKA between the PS and CR groups, such as knee angle, moment, and force. The dynamic ROM of the CR group was greater than that of the PS group (p<0.001). Both the PS and CR groups showed significant deficiencies in flexion and extension function, including knee flexion moment, extension force, maximum flexion angle, and dynamic ROM, compared to healthy individuals. Throughout the gait cycle, both the PS and CR groups showed better knee joint stability compared to healthy individuals.

Conclusion: At six months postoperatively, both the PS and CR groups' gait patterns did not recover to a healthy state, and the CR group's gait pattern was more similar to OA. Compared to PS TKA, CR TKA allowed for greater dynamic ROM during gait. Despite exhibiting superior knee stability during gait, both implants' knee kinematics function remained inferior compared to healthy individuals.

Objectives: In this study, we aimed to evaluate microvascular changes using nailfold capillaroscopy in patients who underwent digit replantation and revascularization.

Patients and methods: A total of 46 patients (34 males, 12 females; mean age: 45.8±17.6 years; range, 18 to 75 years) who underwent replantation or revascularization procedures between February 2012 and May 2023 were retrospectively analyzed. Nailfold capillaroscopy images were assessed for various parameters including capillary count, diameter, dilatation, presence of giant capillaries, capillary disarrangement, microhemorrhages, neoangiogenesis, subpapillary plexus appearance, crossing capillaries, tortuosity, and microaneurysm. We investigated the association between microvascular alterations and clinical outcomes.

Results: Of 46 patients, 25 patients underwent replantation and 21 patients underwent revascularization. Significant microvascular changes, including subpapillary venous plexus, microvascular enlargement, microhemorrhages, neoangiogenesis, and tortuosity were observed in replantation patients (p=0.000^b, p=0.020, p=0.021^b, p=0.001, and p=0.004, respectively). However, these changes were not significant in revascularization patients. Revascularization patients exhibited an increase in capillary diameter and disarrangement (p=0.019 and p=0.016^b, respectively). A significant negative correlation existed between digital nerve repairs and microvascular enlargement in replantation patients. Hyperesthesia was significantly correlated with neoangiogenesis and capillary disarrangement, while a statistically significant positive relationship was found between subpapillary venous plexus and patient satisfaction in replantation patients.

Conclusion: Our study showed that replantation patients who underwent two nerve repairs exhibited a well-regulated microvascular tone. However, we did not observe a statistically significant relationship between the number of nerve repairs and cold intolerance. Based on these findings, we highlight the potential of nailfold capillaroscopy in detecting microvascular changes following replantation and revascularization, which may contribute to a better understanding of the etiology of neurovascular complications.