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Biomimetic Scaffolds for Regeneration of Temporomandibular Joint Disc: A Narrative Review. 用于颞下颌关节盘再生的仿生支架:叙述性综述。
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2023.97625.2024
Hojat Rezazadeh, Nazafarin Samiraninezhad, Mostafa Rezaee

Defects and dysfunctions of temporomandibular joint (TMJ) disc are responsible for the majority of TMJ diseases. Current treatments in this matter are usually short-term and only palliative, thus an alternative treatment that offers long-lasting repair is in great demand. In recent years great attempts have been made to prepare an ideal scaffold, which best resembles the native TMJ disc in characteristics such as mechanical, physical and biological properties. This narrative review focuses on developments of the recent ten years in fabrication of scaffolds using decellularized tissues, natural and synthetic biomaterials for regeneration of TMJ disc and compared their properties. PubMed and Google Scholar databases were searched using the following keywords ("TMJ" OR "temporomandibular joint" OR "TMD" OR "temporomandibular disease") AND ("scaffold" OR "hydrogels"). Randomized controlled trials, randomized clinical trials, case-controls, case reports, and animal studies were included. Comments, systematic reviews, meta-analyses, and non-English papers were excluded. The study concluded that hybrid scaffolds have exhibited favorable cell attachment and proliferation. Synthetic scaffolds have shown promise in providing better control over structural properties; however, additional processes are often required to provide biomimetic cell signaling. While there is still much to learn about the ideal scaffold for TMJ disc regeneration, both natural and synthetic scaffolds have shown promise in achieving the functional, structural, biological, and mechanical properties of a native TMJ disc.

颞下颌关节(TMJ)椎间盘的缺陷和功能障碍是造成大多数颞下颌关节疾病的原因。目前的治疗方法通常都是短期的,只能起到缓解作用,因此,人们亟需一种能提供持久修复的替代治疗方法。近年来,人们一直在努力制备一种理想的支架,这种支架在机械、物理和生物特性等方面与原生颞下颌关节椎间盘最为相似。本综述重点介绍了近十年来使用脱细胞组织、天然和合成生物材料制作支架用于颞下颌关节盘再生的发展情况,并对其特性进行了比较。使用以下关键词("TMJ "或 "颞下颌关节 "或 "TMD "或 "颞下颌关节病")和("支架 "或 "水凝胶")在 PubMed 和 Google Scholar 数据库中进行检索。包括随机对照试验、随机临床试验、病例对照、病例报告和动物实验。评论、系统综述、荟萃分析和非英文论文被排除在外。研究认为,混合支架表现出良好的细胞附着和增殖能力。合成支架在更好地控制结构特性方面已显示出前景;然而,要提供仿生细胞信号,通常还需要额外的过程。虽然在颞下颌关节盘再生的理想支架方面还有很多需要学习的地方,但天然支架和合成支架在实现原生颞下颌关节盘的功能、结构、生物和机械特性方面都显示出了前景。
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引用次数: 0
Comparison of Dental Caries Risk Assessment Using CaRisk- A Simple Mobile Based Application and WHO deft, DMFT Scores: A Cross Sectional Study. 使用 CaRisk(一种基于移动设备的简单应用程序)和世卫组织 deft、DMFT 评分进行龋齿风险评估的比较:一项横断面研究。
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2023.98075.2051
Canty Sandra S, Aparna S, Parangimalai Diwakar Madan Kumar

Statement of the problem: It is essential to address caries risk at an early stage for the prevention of dental caries. Mobile application CaRisk is designed in a particular way to self-assess the dental caries risk by the individual's themselves.

Purpose: The current study aimed to assess the dental caries risk among age groups 5-6 and 35-44 using self-assessment caries risk mobile application CaRisk and compare it with the deft and DMFT values.

Materials and method: This cross-sectional study was conducted in Chennai, India; to evaluate the risk of dental caries in children aged 5 to 6 and adults aged 35 to 44. The scores of the mobile application CaRisk and the decayed- extracted- filled teeth (deft)/ decayed-missing-filled-teeth (DMFT) caries risk assessment were evaluated. Descriptive statistics were performed. The risk category was determined by frequency. Chi-square analysis was done to determine whether the DMFT scores and the CaRisk mobile app were associated. The correlation was performed between the CaRisk mobile application and DMFT scores.

Results: Association was found between the caries risk assessment score of the mobile application CaRisk and the DMFT and deft scores of the adults and children for both the age groups 5-6 and 35-44 years respectively and it indicates that it was found to be statistically significant. Pearson's correlation was performed to assess the strength of association and R-values obtained for the age group 5-6 and 35-44 years respectively, which was statistically significant (0.892 and 0.840).

Conclusion: This CaRisk mobile application scores correlate with the deft and DMFT scores and it is an effective self-diagnosis tool for assessing dental caries risk assessment. Further, it is suggested that the mobile application CaRisk should be tested among a huge population.

问题陈述:为预防龋齿,在早期阶段解决龋齿风险问题至关重要。目的:本研究旨在使用自我评估龋齿风险的移动应用程序 CaRisk 评估 5-6 岁和 35-44 岁年龄组的龋齿风险,并将其与 deft 值和 DMFT 值进行比较:这项横断面研究在印度钦奈进行,目的是评估 5-6 岁儿童和 35-44 岁成人的龋齿风险。研究评估了手机应用软件 CaRisk 和蛀牙-拔牙-补牙(deft)/蛀牙-缺失-补牙(DMFT)龋齿风险评估的得分。对结果进行了描述性统计。根据频率确定风险类别。为确定 DMFT 分数和 CaRisk 移动应用程序是否相关,进行了卡方分析。对 CaRisk 移动应用程序和 DMFT 分数进行了相关性分析:结果:发现移动应用程序 CaRisk 的龋齿风险评估得分与 5-6 岁年龄组和 35-44 岁年龄组成人和儿童的 DMFT 和 deft 分数之间存在相关性,且在统计学上具有显著意义。对 5-6 岁年龄组和 35-44 岁年龄组分别进行了皮尔逊相关性分析,以评估两者之间的关联强度和 R 值,结果显示两者之间的关联具有统计学意义(0.892 和 0.840):CaRisk 移动应用程序的评分与 deft 和 DMFT 评分相关,是评估龋齿风险的有效自我诊断工具。此外,建议在大量人群中测试 CaRisk 移动应用程序。
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引用次数: 0
Odontogenic Tumors: A Challenge for Clinical Diagnosis and an Opportunity for AI Innovation. 牙源性肿瘤:临床诊断的挑战与人工智能创新的机遇。
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2024.101237.2284
Mohamad Reza Golzar Feshalami, Mehraban Shahi, Nasrin Davari Dolatabadi
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引用次数: 0
Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial. 评估盐酸苄达明对咽反射强度的影响:一项随机单盲临床试验。
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2023.97675.2032
Mohammad Mehdi Torabi, Reyhaneh Shoorgashti, Farnaz Haji Fattahi, Simin Lesan

Statement of the problem: Gag reflex is among the most common problems during dental and endoscopic procedures. Benzydamine hydrochloride is a non-steroidal anti-inflammatory medication and a local anesthetic that might be useful in reducing the gag reflex.

Purpose: This study aimed to evaluate the effects of benzydamine hydrochloride mouthwash on the intensity of the gag reflex.

Materials and method: In this randomized clinical trial study, 30 participants aged 21-26 with a gag trigger point index (GTPI) higher than 2 were divided into 2 groups. In the case group, 15 ml of 0.15% benzydamine hydrochloride mouthwash was gargled for 1 minute, and after 10 minutes GTPI test was conducted. In the control group, 4 puffs of 10% lidocaine spray were applied to the mucosa of the targeted area, and after 5 minutes, GTPI was measured. Participants were asked about the taste and smell of the medications.

Results: GTPI was significantly reduced in both groups. In the lidocaine group, the GTPI score changed from 4.47 to 2.00 (p< 0.001), and that for the benzydamine group was 4.20 to 1.47 (p< 0.001). The variance rate of the gag reflex was -2.73 and -2.47 in the benzydamine group and lidocaine group, respectively. However, this reduction was not statistically significant between the two groups. Moreover, benzydamine mouthwash has a significantly better taste and smell than lidocaine (p= 0.001).

Conclusion: The results of this study showed that benzydamine mouthwash could be used quite effectively in reducing the gag reflex.

问题简介:咽反射是牙科和内窥镜手术中最常见的问题之一。目的:本研究旨在评估盐酸苄达明漱口水对吞咽反射强度的影响:在这项随机临床试验研究中,30 名年龄在 21-26 岁、咽触发点指数(GTPI)高于 2 的参与者被分为 2 组。病例组使用 15 毫升 0.15%盐酸苄达明漱口水漱口 1 分钟,10 分钟后进行 GTPI 测试。在对照组中,在目标区域的粘膜上喷 4 口 10%利多卡因喷雾,5 分钟后测量 GTPI。参与者被问及药物的味道和气味:结果:两组 GTPI 均明显下降。利多卡因组的 GTPI 分数从 4.47 降至 2.00(P< 0.001),苯扎溴铵组的 GTPI 分数从 4.20 降至 1.47(P< 0.001)。咽反射的变异率在苄达明组和利多卡因组分别为-2.73和-2.47。然而,两组之间的差异并无统计学意义。此外,苄达明漱口水的味道和气味明显优于利多卡因(P= 0.001):本研究结果表明,苄达明漱口水可有效减少吞咽反射。
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引用次数: 0
Two Palatal Roots in Maxillary First Molar, a Rare Entity: Report of Two Cases. 上颌第一磨牙中的两个腭根,一种罕见情况:两个病例的报告
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2023.98649.2101
Vineeta Nikhil, Padmanabh Jha, Preeti Mishra, Sonal Sahu, Abhishek Bhargava

An in-depth understanding of the anatomical variations of maxillary molars is essential for endodontic success. Unlike the maxillary second molars, the presence of a second palatal root is uncommon in the first maxillary molar. This case report describes two cases of non-surgical management of maxillary molars with extra palatal roots. Careful clinical examination, knowledge of the internal anatomy, and the use of advanced radiographic modalities like cone beam computed tomography (CBCT) can reveal the presence of variations in the internal and external anatomy of any tooth. Therefore, for nonsurgical as well as surgical management clinicians should always watch out for any deviations in a tooth and utilize all the available tools to diagnose and manage them successfully.

深入了解上颌磨牙的解剖变异对于牙髓治疗的成功至关重要。与上颌第二磨牙不同,在上颌第一磨牙中存在第二个腭根的情况并不常见。本病例报告描述了两例上颌磨牙腭外根的非手术治疗。仔细的临床检查、对内部解剖结构的了解以及锥形束计算机断层扫描(CBCT)等先进放射模式的使用可以发现任何牙齿内部和外部解剖结构的变化。因此,无论是非手术治疗还是手术治疗,临床医生都应时刻注意牙齿的任何偏差,并利用所有可用的工具对其进行成功的诊断和治疗。
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引用次数: 0
A Cone-Beam Computed Tomography-Based Evaluation of Root Dilaceration in Permanent Premolars: A Retrospective Study. 基于锥形束计算机断层扫描的恒前磨牙牙根扩张评估:回顾性研究
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2023.98244.2067
Bahar Asheghi, Safoora Sahebi, Zeinab Rafiee, Maryam Zangooei Booshehri, Afsane Habibi

Statement of the problem: As a developmental disorder characterized by an abnormal bend and angle in the longitudinal axis of the tooth root, dilaceration can cause complications in routine dental procedures such as endodontics, orthodontics, and surgical treatments.

Purpose: The purpose of this study was to investigate the prevalence of dilaceration in maxillary and mandibular premolar teeth in a population of Shiraz city based on cone-beam computed tomography (CBCT).

Materials and method: This is a retrospective cross-sectional study on 927 premolar teeth and 132 CBCT radiographs of patients obtained from four private radiology clinics in Shiraz (Iran). In this study, the presence, location, direction, and severity of dilaceration in premolar roots as well as its relationship with gender were investigated. Chi-square and Fisher tests were used to analyze the data.

Results: The results showed that 17% of the studied 927 teeth had dilaceration. The prevalence of dilaceration was significantly higher in women than in men (20.3% vs. 13.6%, p= 0.005). The dilaceration rates were significantly higher in the mandibular first and second premolar teeth (31.6% and 26%, p= 0.002) than in the other teeth. In addition, the highest prevalence was in the distal direction with mild severity in the apical third of the root (p< 0.001).

Conclusion: According to the results of this study, the prevalence of dilaceration was relatively high in mandibular premolar teeth especially in women.

问题陈述:作为一种以牙根纵轴异常弯曲和角度为特征的发育障碍,牙根扩张可能会在牙髓治疗、正畸和外科治疗等常规牙科手术中引起并发症。目的:本研究的目的是基于锥束计算机断层扫描(CBCT),调查设拉子市人群中上颌和下颌前磨牙牙根扩张的患病率:这是一项回顾性横断面研究,研究对象是设拉子(伊朗)四家私人放射科诊所的 927 颗前臼齿和 132 张患者 CBCT X 光片。本研究调查了前磨牙牙根扩张的存在、位置、方向和严重程度及其与性别的关系。数据分析采用了卡方检验和费雪检验:结果显示,在研究的 927 颗牙齿中,有 17% 的牙齿存在牙根扩张。女性的牙齿扩张率明显高于男性(20.3% 对 13.6%,P= 0.005)。下颌第一和第二前磨牙的扩张率(31.6% 和 26%,p= 0.002)明显高于其他牙齿。此外,远端方向的发病率最高,根尖三分之一处的严重程度较轻(p< 0.001):根据这项研究的结果,下颌前磨牙尤其是女性下颌前磨牙的扩张率相对较高。
{"title":"A Cone-Beam Computed Tomography-Based Evaluation of Root Dilaceration in Permanent Premolars: A Retrospective Study.","authors":"Bahar Asheghi, Safoora Sahebi, Zeinab Rafiee, Maryam Zangooei Booshehri, Afsane Habibi","doi":"10.30476/dentjods.2023.98244.2067","DOIUrl":"10.30476/dentjods.2023.98244.2067","url":null,"abstract":"<p><strong>Statement of the problem: </strong>As a developmental disorder characterized by an abnormal bend and angle in the longitudinal axis of the tooth root, dilaceration can cause complications in routine dental procedures such as endodontics, orthodontics, and surgical treatments.</p><p><strong>Purpose: </strong>The purpose of this study was to investigate the prevalence of dilaceration in maxillary and mandibular premolar teeth in a population of Shiraz city based on cone-beam computed tomography (CBCT).</p><p><strong>Materials and method: </strong>This is a retrospective cross-sectional study on 927 premolar teeth and 132 CBCT radiographs of patients obtained from four private radiology clinics in Shiraz (Iran). In this study, the presence, location, direction, and severity of dilaceration in premolar roots as well as its relationship with gender were investigated. Chi-square and Fisher tests were used to analyze the data.</p><p><strong>Results: </strong>The results showed that 17% of the studied 927 teeth had dilaceration. The prevalence of dilaceration was significantly higher in women than in men (20.3% vs. 13.6%, <i>p</i>= 0.005). The dilaceration rates were significantly higher in the mandibular first and second premolar teeth (31.6% and 26%, <i>p</i>= 0.002) than in the other teeth. In addition, the highest prevalence was in the distal direction with mild severity in the apical third of the root (<i>p</i>< 0.001).</p><p><strong>Conclusion: </strong>According to the results of this study, the prevalence of dilaceration was relatively high in mandibular premolar teeth especially in women.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"155-161"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217063/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the Acceptable Range of Lips and Chin Position in Two Different Geographical Zones of Iran among Laypersons. 评估伊朗两个不同地理区域的普通人对嘴唇和下巴位置的可接受范围。
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2023.97251.2003
Farzaneh Golfeshan, Athar Nasseri Mojarad, Ahmad Reza Sardarian

Statement of the problem: The position of the chin and lips are important components in the lower third of the face and can be changed by orthodontic treatment. It seems that factors such as diversity in culture, ethnicity, and place of residence are among the factors affecting people's perception of beauty. Iran, as a vast country, contains different ethnicities and cultures, and of course, it is not exempt from this point of view.

Purpose: Our purpose of conducting this study is to investigate the impact of the difference in living environment and culture on people's aesthetic perception. Orthodontists and oral surgeons can use these data to choose the best treatment plan for the patients according to their geographical zones.

Material and method: A descriptive cross-sectional study was conducted to evaluate the perception of lips and chin position. A series of 25 profile images were prepared in 5 sets. Each set contained 5 profile images. Northern and Southern lay people and orthodontists were asked to evaluate the profile series of each set in 1 session and score them from 1 to 5: 1, very unattractive; 2, unattractive; 3, neither attractive nor unattractive; 4, attractive; or 5, very attractive.

Results: 652 participants in 3 groups, including 16 orthodontists (10 men and 6 women), 318 lay people of the North of Iran (172 men and 138 women), and 318 lay people of the South of Iran (175 men and 139 women) participated in this study. Regardless of the chin position, normal lip position and slight changes of that (in both protruded and retruded positions) were more favorable for all three groups. The images with moderately retruded lips were scored as the least attractive by all three groups and orthodontist gave the lowest score to these profiles. Southern people could better tolerate moderately retruded lips than other two groups. In the fifth series, orthodontists preferred slightly and moderately protruded lips in comparison to other two groups of laypeople.

Conclusion: Regardless of the chin position, normal and slightly (-2mm to +2mm) protruded and retruded lips were more favorable in all three groups. Southern people could better tolerate moderately retruded lips than the two other groups.

问题简介:下巴和嘴唇的位置是面部下三分之一的重要组成部分,可以通过正畸治疗来改变。文化、种族和居住地的多样性似乎是影响人们对美的看法的因素之一。伊朗作为一个幅员辽阔的国家,包含了不同的民族和文化,当然也不例外。目的:我们进行这项研究的目的是调查生活环境和文化的差异对人们审美观念的影响。正畸医生和口腔外科医生可以利用这些数据,根据地理区域的不同为患者选择最佳的治疗方案:为评估人们对嘴唇和下巴位置的感知,我们进行了一项描述性横断面研究。研究人员将 25 张轮廓图像分成 5 组。每组包含 5 张轮廓图像。要求北方和南方的非专业人士及正畸医生在一次会议中对每组轮廓系列进行评估,并从 1 到 5 分进行打分:1 分,非常不美;2 分,不美;3 分,既不美也不不美;4 分,美;或 5 分,非常美:652 名参与者分 3 组参加了此次研究,其中包括 16 名牙齿矫正专家(10 名男性和 6 名女性)、318 名伊朗北部的普通人(172 名男性和 138 名女性)以及 318 名伊朗南部的普通人(175 名男性和 139 名女性)。无论下巴位置如何,嘴唇位置正常和轻微变化(突出和后缩位置)对所有三组人都更有利。三组人都认为嘴唇适度后翘的图片最不吸引人,而正畸医生给这些图片打的分数最低。与其他两组人相比,南方人对嘴唇适度后翘的容忍度更高。在第五个系列中,与其他两组非专业人士相比,正畸医生更喜欢轻微和中度后突的嘴唇:无论下巴位置如何,正常和轻微(-2 毫米至 +2 毫米)突出和后缩的嘴唇在所有三个组别中都更受欢迎。南方人对中度后翘嘴唇的耐受性要好于其他两组人。
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引用次数: 0
Role of Platelet Concentrates in Dental-Pulp Regeneration: A Systematic Review of Randomized Clinical Trials. 血小板浓缩物在牙髓再生中的作用:随机临床试验的系统回顾。
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2023.96000.1912
Zahra Kiaipour, Mahdieh Shafiee, Ghassem Ansari

Statement of the problem: Treatment of immature necrotic teeth is a problematic situation. Conventional root canal therapy is challenging and leaves a weak, fragile, and undeveloped tooth for lifetime.

Purpose: This review was aimed to assess the outcome of available randomized clinical trials (RCTs) on the efficacy of platelet concentrates (PC) in dentine-pulp complex regeneration.

Materials and method: In this systematic review, an electronic search was conducted on MEDLINE, EMBASE, Cochrane, and Google scholar databases. A further manual search was performed on the list of related articles in order to ensure inclusion of potentially missed articles in earlier electronic search. Those proved RCTs matched with the standard criteria were included following an initial assessment of abstracts and the text independently by the reviewers.

Results: From the total 602 harvested articles, only 13 met the criteria and were evaluated with 11 having parallel design and 2 split mouth. Only one study featured low risk of bias, while three had moderate risk and the rest were at high risk of bias. Six studies had used platelet rich plasma (PRP), 4 employed platelet rich fibrin (PRF), one utilized injectable platelet rich fibrin (I-PRF), and three used both PRF and PRP for their experimental groups while blood clot (BC) was used as the control group for all. The success rate was reported at 87.3% judged by the absence of pathologic signs and symptoms.

Conclusion: Dentin wall thickening, root lengthening and apex closure were higher in PC groups, however, these differences were not statistically significant in reported studies. It can be concluded that PCs promote the pulp tissue revitalization and continuation of root development. However, a consensus on its potency for true pulp regeneration is yet to be reached.

问题陈述:未成熟坏死牙的治疗是一个难题。目的:本综述旨在评估关于血小板浓缩物(PC)在牙本质-牙髓复合体再生中疗效的现有随机临床试验(RCT)的结果:本系统性综述在 MEDLINE、EMBASE、Cochrane 和 Google scholar 数据库中进行了电子检索。为了确保纳入之前电子检索中可能遗漏的文章,还对相关文章列表进行了进一步人工检索。在审稿人独立对摘要和正文进行初步评估后,那些经证实符合标准的 RCT 被纳入其中:在总共 602 篇被收录的文章中,只有 13 篇符合标准并进行了评估,其中 11 篇采用平行设计,2 篇采用分口设计。只有一项研究存在低偏倚风险,三项研究存在中度偏倚风险,其余研究存在高度偏倚风险。6 项研究使用了富血小板血浆(PRP),4 项研究使用了富血小板纤维蛋白(PRF),1 项研究使用了可注射的富血小板纤维蛋白(I-PRF),3 项研究的实验组同时使用了富血小板纤维蛋白和 PRP,所有研究的对照组均为血凝块(BC)。根据无病理症状和体征判断,成功率为 87.3%:结论:PC 组的牙本质壁增厚、牙根延长和牙尖闭合程度更高,但这些差异在已报道的研究中并无统计学意义。可以得出结论,多糖可促进牙髓组织的再生和牙根的继续发育。不过,关于多氯化萘对真正牙髓再生的功效,目前尚未达成共识。
{"title":"Role of Platelet Concentrates in Dental-Pulp Regeneration: A Systematic Review of Randomized Clinical Trials.","authors":"Zahra Kiaipour, Mahdieh Shafiee, Ghassem Ansari","doi":"10.30476/dentjods.2023.96000.1912","DOIUrl":"10.30476/dentjods.2023.96000.1912","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Treatment of immature necrotic teeth is a problematic situation. Conventional root canal therapy is challenging and leaves a weak, fragile, and undeveloped tooth for lifetime.</p><p><strong>Purpose: </strong>This review was aimed to assess the outcome of available randomized clinical trials (RCTs) on the efficacy of platelet concentrates (PC) in dentine-pulp complex regeneration.</p><p><strong>Materials and method: </strong>In this systematic review, an electronic search was conducted on MEDLINE, EMBASE, Cochrane, and Google scholar databases. A further manual search was performed on the list of related articles in order to ensure inclusion of potentially missed articles in earlier electronic search. Those proved RCTs matched with the standard criteria were included following an initial assessment of abstracts and the text independently by the reviewers.</p><p><strong>Results: </strong>From the total 602 harvested articles, only 13 met the criteria and were evaluated with 11 having parallel design and 2 split mouth. Only one study featured low risk of bias, while three had moderate risk and the rest were at high risk of bias. Six studies had used platelet rich plasma (PRP), 4 employed platelet rich fibrin (PRF), one utilized injectable platelet rich fibrin (I-PRF), and three used both PRF and PRP for their experimental groups while blood clot (BC) was used as the control group for all. The success rate was reported at 87.3% judged by the absence of pathologic signs and symptoms.</p><p><strong>Conclusion: </strong>Dentin wall thickening, root lengthening and apex closure were higher in PC groups, however, these differences were not statistically significant in reported studies. It can be concluded that PCs promote the pulp tissue revitalization and continuation of root development. However, a consensus on its potency for true pulp regeneration is yet to be reached.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 2","pages":"97-107"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of a Localized Stage III Periodontitis in the Esthetic Zone with Guided Tissue Regeneration Technique on a Heavy Smoker Patient with 12-Year Follow- up: A Case Report. 用引导组织再生技术治疗一名重度吸烟患者的修复区局部 III 期牙周炎并随访 12 年:病例报告。
Pub Date : 2024-06-01 DOI: 10.30476/dentjods.2024.100483.2224
Fatme Mouchref Hamasni, Fady El Hajj

This case report exhibits a heavy smoker female patient with a localized stage III periodontitis who has been under the smoking cessation program during the pre-surgical period, followed by a strict maintenance program for the past twelve years, after being treated with guided tissue regeneration techniques and restored with zirconia prosthetic crowns. A 50-year-old, heavy smoker (> 40 cigarettes per day), systemically healthy female patient presented complaining of mobility and pain in the upper right central incisor, which was temporarily splinted to the left central incisor using resin composite. After clinical and radiographic examination, significant damage of the attachment apparatus, deep periodontal lesions extending the middle portion of the root, and severe infrabony defect were noted. Following the initial hygienic phase, a guided tissue regeneration surgery using xenograft bone substitute covered by a resorbable collagen membrane was performed. After six months of healing, four zirconia crowns were cemented on the central and lateral incisors based on patient esthetic compliance. During the 12-year follow-up period, neither residual pockets nor gingival recession were observed, and perfect marginal bone stability, and esthetic and functional results were noted. This case shows the predictability of a conservative surgical technique, the guided tissue regeneration, based on appropriate treatment planning and a strict maintenance program. It also demonstrates the importance of at least a 6-month healing period after such surgeries, allowing complete tissue maturation and a re-establishment of the supra osseous gingival tissues in order to locate the prosthetic margins without interfering with the soft tissues integrity.

本病例报告展示了一名患有局部 III 期牙周炎的重度吸烟女性患者,该患者在手术前接受了戒烟计划,随后在过去的 12 年中一直接受严格的维护计划,术后采用引导组织再生技术进行治疗,并用氧化锆修复冠进行修复。一位 50 岁的重度吸烟者(每天吸烟超过 40 支)、全身健康的女性患者主诉右上中切牙移动和疼痛,使用树脂复合材料将其临时夹板固定在左上中切牙上。经过临床和影像学检查,发现附着器明显受损,深牙周病损延伸至牙根中部,牙槽骨下缺损严重。在最初的卫生阶段后,使用异种骨替代物和可吸收胶原膜进行了引导组织再生手术。六个月愈合后,根据患者的审美要求,在中切牙和侧切牙上粘接了四个氧化锆牙冠。在长达 12 年的随访期间,既没有发现残余牙周袋,也没有发现牙龈退缩,边缘骨的稳定性、美观性和功能性都非常完美。该病例表明,基于适当的治疗规划和严格的维护计划,保守的外科技术--引导组织再生--具有可预见性。该病例还说明了此类手术后至少 6 个月愈合期的重要性,这段时间可以让组织完全成熟,重新建立骨上龈组织,以便在不影响软组织完整性的情况下确定修复体边缘的位置。
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引用次数: 0
Computer Assisted Bone Age Estimation Using Dimensions of Metacarpal Bones and Metacarpophalangeal Joints Based on Neural Network. 利用基于神经网络的掌骨和掌指关节尺寸进行计算机辅助骨龄估计
Pub Date : 2024-03-01 DOI: 10.30476/dentjods.2023.95629.1882
Abdolaziz Haghnegahdar, Hamid Reza Pakshir, Mojtaba Zandieh, Ilnaz Ghanbari

Statement of the problem: Bone age is a more accurate assessment for biologic development than chronological age. The most common method for bone age estimation is using Pyle and Greulich Atlas. Today, computer-based techniques are becoming more favorable among investigators. However, the morphological features in Greulich and Pyle method are difficult to be converted into quantitative measures. During recent years, metacarpal bones and metacarpophalangeal joints dimensions were shown to be highly correlated with skeletal age.

Purpose: In this study, we have evaluated the accuracy and reliability of a trained neural network for bone age estimation with quantitative and recently introduced related data, including chronological age, height, trunk height, weight, metacarpal bones, and metacarpophalangeal joints dimensions.

Materials and method: In this cross sectional retrospective study, aneural network, using MATLAB, was utilized to determine bone age by employing quantitative features for 304 subjects. To evaluate the accuracy of age estimation software, paired t-test, and inter-class correlation was used.

Results: The difference between the mean bone ages determined by the radiologists and the mean bone ages assessed by the age estimation software was not significant (p Value= 0.119 in male subjects and p= 0.922 in female subjects). The results from the software and radiologists showed a strong correlation -ICC=0.990 in male subjects and ICC=0.986 in female subjects (p< 0.001).

Conclusion: The results have shown an acceptable accuracy in bone age estimation with training neural network and using dimensions of bones and joints.

问题陈述:骨龄是比实际年龄更准确的生物发育评估方法。最常用的骨龄估计方法是使用 Pyle 和 Greulich 图集。如今,计算机技术越来越受到研究人员的青睐。然而,Greulich 和 Pyle 方法中的形态特征很难转化为定量测量。近年来,掌骨和掌指关节的尺寸被证明与骨骼年龄高度相关。目的:在这项研究中,我们利用定量和最新引入的相关数据,包括年代年龄、身高、躯干高度、体重、掌骨和掌指关节尺寸,评估了训练有素的神经网络在骨龄估计方面的准确性和可靠性:在这项横断面回顾性研究中,利用 MATLAB 神经网络,通过定量特征确定 304 名受试者的骨龄。为了评估年龄估算软件的准确性,采用了配对 t 检验和类间相关性检验:结果:放射科医生确定的平均骨龄与年龄估算软件评估的平均骨龄之间的差异不显著(男性受试者的 p 值= 0.119,女性受试者的 p= 0.922)。软件和放射科医生的结果显示出很强的相关性--男性受试者的ICC=0.990,女性受试者的ICC=0.986(p< 0.001):结果表明,通过训练神经网络并使用骨骼和关节的尺寸估算骨龄的准确性是可以接受的。
{"title":"Computer Assisted Bone Age Estimation Using Dimensions of Metacarpal Bones and Metacarpophalangeal Joints Based on Neural Network.","authors":"Abdolaziz Haghnegahdar, Hamid Reza Pakshir, Mojtaba Zandieh, Ilnaz Ghanbari","doi":"10.30476/dentjods.2023.95629.1882","DOIUrl":"10.30476/dentjods.2023.95629.1882","url":null,"abstract":"<p><strong>Statement of the problem: </strong>Bone age is a more accurate assessment for biologic development than chronological age. The most common method for bone age estimation is using Pyle and Greulich Atlas. Today, computer-based techniques are becoming more favorable among investigators. However, the morphological features in Greulich and Pyle method are difficult to be converted into quantitative measures. During recent years, metacarpal bones and metacarpophalangeal joints dimensions were shown to be highly correlated with skeletal age.</p><p><strong>Purpose: </strong>In this study, we have evaluated the accuracy and reliability of a trained neural network for bone age estimation with quantitative and recently introduced related data, including chronological age, height, trunk height, weight, metacarpal bones, and metacarpophalangeal joints dimensions.</p><p><strong>Materials and method: </strong>In this cross sectional retrospective study, aneural network, using MATLAB, was utilized to determine bone age by employing quantitative features for 304 subjects. To evaluate the accuracy of age estimation software, paired t-test, and inter-class correlation was used.</p><p><strong>Results: </strong>The difference between the mean bone ages determined by the radiologists and the mean bone ages assessed by the age estimation software was not significant (<i>p</i> Value= 0.119 in male subjects and <i>p</i>= 0.922 in female subjects). The results from the software and radiologists showed a strong correlation -ICC=0.990 in male subjects and ICC=0.986 in female subjects (<i>p</i>< 0.001).</p><p><strong>Conclusion: </strong>The results have shown an acceptable accuracy in bone age estimation with training neural network and using dimensions of bones and joints.</p>","PeriodicalId":73702,"journal":{"name":"Journal of dentistry (Shiraz, Iran)","volume":"25 1","pages":"51-58"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10963864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Journal of dentistry (Shiraz, Iran)
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