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Clinical Profile of Muscular Dystrophies in Burkina Faso 布基纳法索肌营养不良症的临床概况
Pub Date : 2018-12-01 DOI: 10.15744/2454-4981.4.301
Dabilgou Aa
Citation: Dabilgou AA, Napon C, Drave A, Kyelem JMA, Kambire Z, et al. (2018) Clinical Profile of Muscular Dystrophies in Burkina Faso. J Neurol Neurol Disord 4(3): 301 ISSN: 2454-4981 To describe clinical profile of muscular dystrophies in Burkina Faso, we retrospectively reviewed 17 patients who had clinical phenotypes of Muscular Dystrophy between 2004 and 2004 in the neurology Department of Yalgado Ouedraogo Teaching Hospital in Ouagadougou.
引文:Dabilgou AA,Napon C,Drave A,Kyelem JMA,Kambire Z等人(2018)布基纳法索肌肉营养不良的临床概况。《神经-神经疾病杂志》4(3):301 ISSN:2454-4981为了描述布基纳法索肌肉营养不良的临床特征,我们回顾性回顾了2004年至2004年间在瓦加杜古Yalgado Ouedraogo教学医院神经内科有肌肉营养不良临床表型的17名患者。
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引用次数: 0
Neuroschistosomiasis Presenting as Conus Medullaris Lesion; A Case Report 以髓锥病变为表现的神经血吸虫病病例报告
Pub Date : 2018-10-01 DOI: 10.15744/2454-4981.4.204
J. Al-Hashel, M. Ibrahim, J. K. John, Ismail, A. Ea
Citation: Al-Hashel JY, Ibrahim MA, John JK, Ismail II, Abdelnabi EA (2018) Neuroschistosomiasis Presenting as Conus Medullaris Lesion; A Case Report. J Neurol Neurol Disord 4(2): 204. doi: 10.15744/2454-4981.4.204 ISSN: 2454-4981 Schistosomiasis is one of the most widespread parasitic diseases in the world. Spinal Cord Schistosomiasis (SCS) usually presents acutely or subacutely and classified into three clinical forms: medullary, myelo-radicular and conus-cauda equina syndrome. Despite the fact that Kuwait is not an endemic country for Schistosomiasis, many expats residing in this country are from endemic areas. We report a case of a 29 years old Egyptian male with conus-cauda equina syndrome with classic radiological findings and good response to treatment. Introduction
引用本文:Al-Hashel JY, Ibrahim MA, John JK, Ismail II, Abdelnabi EA(2018)神经血吸虫病表现为髓锥病变;一个病例报告。中华神经科杂志[J] .中华神经科杂志,2011(2):393。血吸虫病是世界上传播最广的寄生虫病之一。脊髓血吸虫病(SCS)通常表现为急性或亚急性,分为三种临床形式:髓系、髓根和马尾圆锥综合征。尽管科威特不是血吸虫病流行的国家,但居住在这个国家的许多外国人都来自流行地区。我们报告一例29岁的埃及男性马尾圆锥综合征与典型的放射检查结果和良好的反应治疗。介绍
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引用次数: 1
“Holoprosencephaly, Newly Born Baby Disorder” “无脑畸形,新生儿疾病”
Pub Date : 2018-10-01 DOI: 10.15744/2454-4981.4.201
S. Shoukat, Sammia Rehman
Citation: Shoukat S, Sheikh I, Rehman SF (2018) “Holoprosencephaly, Newly Born Baby Disorder”. J Neurol Neurol Disord 4(2): 201. doi: 10.15744/2454-4981.4.201
引文:Shoukat S,Sheikh I,Rehman SF(2018)“无脑畸形,新生儿疾病”。神经-神经疾病杂志4(2):201。doi:10.15744/2454-4981.4.201
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引用次数: 0
Postural Impairment of Adults and Adolescents Cerebral Palsy Inpatients at the Retaguarda Hospital of Ribeirão Preto-SP ribebeo Preto-SP雷塔瓜达医院成人和青少年脑瘫住院患者的姿势障碍
Pub Date : 2018-06-01 DOI: 10.15744/2454-4981.4.104
Lopes Rrb, T. Mestriner, Costa Csn, Pfeifer Li
Citation: Lopes RRB, Mestriner T, Costa CSN, Pfeifer LI (2018) Postural Impairment of Adults and Adolescents Cerebral Palsy Inpatients at the Retaguarda Hospital of Ribeirão Preto-SP. J Neurol Neurol Disord 4(1): 104
引用本文:Lopes RRB, Mestriner T, Costa CSN, Pfeifer LI (2018) ribeirbeo Preto-SP Retaguarda医院成人和青少年脑瘫住院患者的姿势障碍。中华神经科杂志,2011 (1):1 - 4
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引用次数: 1
Drugs of Abuse and Addiction - Overview and Current Status 滥用和成瘾药物-概述和现状
Pub Date : 2018-06-01 DOI: 10.15744/2454-4981.4.106
Khanh Nd
Citation: Khanh ND (2018) Drugs of Abuse and Addiction Overview and Current Status. J Neurol Neurol Disord 4(1): 106
引文:Khanh ND(2018)药物滥用和成瘾概述和现状。神经神经疾病杂志4(1):106
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引用次数: 0
Mental Health Distress and Wellness among Medical Students 医学生心理健康状况调查
Pub Date : 2018-06-01 DOI: 10.15744/2454-4981.4.102
Liranso Gs, Vicky Vd, Mohan Ss, M. Prakash
Citation: Liranso GS, Mohan SS, Prakash M, Vicky VD (2018) Mental Health Distress and Wellness among Medical Students. J Neurol Neurol Disord 4(1): 102
引文:Liranso GS,Mohan SS,Prakash M,Vicky VD(2018)医学生的心理健康困扰与健康。神经神经疾病杂志4(1):102
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引用次数: 0
Acute Disseminated Encephalomyelitis (ADEM): Short Term Motor Outcome of Hospital Admitted Patients 急性播散性脑脊髓炎(ADEM):住院患者的短期运动结果
Pub Date : 2018-06-01 DOI: 10.15744/2454-4981.4.105
A. Azam, Hassanuzz aman, S. Majumdar, Kayasthagir Pk, Kh Ma, M. Sam, Z. Ahammed, Babul Mr, M. Karim, M. Rahman
Citation: Azam A, Hassanuzzaman, Majumdar S, kayasthagir PK, khandaker MA, et al. (2018) Acute Disseminated Encephalomyelitis (ADEM): Short Term Motor Outcome of Hospital Admitted Patients. J Neurol Neurol Disord 4(1): 105
引文:Azam A,Hassanuzzaman,Majumdar S,kayastagir PK,khandaker MA等人(2018)急性播散性脑脊髓炎(ADEM):住院患者的短期运动结果。神经神经疾病杂志4(1):105
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引用次数: 0
Rebleeding In Central Nervous System after Use of Rivaroxaban for Treatment of Deep Venous Thrombosis in a Patient with Cerebral Vasculitis 利伐沙班治疗脑血管炎患者深静脉血栓形成后中枢神经系统再出血1例
Pub Date : 2018-06-01 DOI: 10.15744/2454-4981.4.103
Silva Jss, Correia Skt, Chaves Bpt, Silva Il, Miranda Tl, Oliveira Dl, Vasconcelos Mjmv, Cavalcanti Tfp, Santos Dbp, Souza Lf
Introduction: Rivaroxaban is a direct, specific inhibitor of Factor Xa, which targets Factor Xa and Factor Xa free and coagulated in the prothrombinase complex. Citation: Silva JSS, Correia SKT, Chaves BPT, Silva IL, Miranda TL, et al. (2017) Rebleeding In Central Nervous System after Use of Rivaroxaban for Treatment of Deep Venous Thrombosis in a Patient with Cerebral Vasculitis. J Neurol Neurol Disord 4(1): 103
利伐沙班是Xa因子的直接特异性抑制剂,靶向Xa因子和游离Xa因子,并在凝血酶原复合体中凝固。引用本文:Silva JSS, Correia SKT, Chaves BPT, Silva IL, Miranda TL等。(2017)利伐沙班治疗脑血管炎患者深静脉血栓形成后中枢神经系统再出血。中华神经科杂志,2011 (1):1 - 4
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引用次数: 0
Complex Assessment of Combat Neurotrauma 战斗神经创伤的复杂评估
Pub Date : 2018-06-01 DOI: 10.15744/2454-4981.4.107
Bowen M, Chang A
Citation: Bowen M, Chang A (2018) Complex Assessment of Combat Neurotrauma. J Neurol Neurol Disord 4(2): 107
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引用次数: 0
Evaluation of Apolipoprotein E Fragmentation as a Biomarker for Alzheimer's Disease. 评估载脂蛋白 E 片段作为阿尔茨海默病生物标记物的作用
Pub Date : 2017-09-01 Epub Date: 2017-07-31 DOI: 10.15744/2454-4981.3.204
J W Gause, R J Day, C A Caraway, W W Poon, T T Rohn

Recent studies have supported a role for the proteolytic cleavage of apolipoprotein E4 (APOE4) as a potential mechanism for the enhanced dementia risk associated with Alzheimer's disease. To determine whether APOE4 fragmentation is correlated with AD, ELISA assays were performed with cerebral spinal fluid (CSF) and plasma samples utilizing an antibody that specifically detects a 17 kDa amino-terminal fragment (p17) of APOE (nApoECF antibody). In CSF samples, levels of APOE fragmentation were minimal in both neuropathological normals (NPNs) and AD cases and there were no significant differences between the two cohorts across APOE genotypes. Similar results were found in plasma samples where the p17 APOE fragment comprised only 8.4% of the total level of identified APOE. As with CSF, there were no significant differences found between NPNs and AD cases in terms of the amount of nApoECF quantified. Taken together, these results suggest that the p17 amino-terminal fragment of APOE is not correlated with AD or APOE genotype in the plasma or CSF.

最近的研究表明,载脂蛋白 E4(APOE4)的蛋白水解裂解是阿尔茨海默病痴呆风险增加的潜在机制之一。为了确定 APOE4 片段是否与阿兹海默病相关,我们使用一种能特异性检测 APOE 17 kDa 氨基末端片段(p17)的抗体(nApoECF 抗体)对脑脊液(CSF)和血浆样本进行了 ELISA 检测。在脑脊液样本中,神经病理学正常人(NPNs)和注意力缺失症病例的APOE片段水平都很低,而且两组人的APOE基因型没有明显差异。在血浆样本中也发现了类似的结果,p17 APOE片段仅占已识别的APOE总水平的8.4%。与 CSF 一样,NPNs 和 AD 病例之间在 nApoECF 的定量方面也没有发现显著差异。综上所述,这些结果表明 APOE 的 p17 氨基末端片段与血浆或 CSF 中的 AD 或 APOE 基因型无关。
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引用次数: 0
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Journal of neurology and neurological disorders
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