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Pharyngocutaneous Fistula after Laryngectomy: An Umbrella Review to Uncover Lacunae in Meta-Analyses 喉切除术后咽皮瘘:荟萃分析中发现咽皮瘘的综述
Pub Date : 2023-10-11 DOI: 10.3390/ohbm4020011
Karthik Nagaraja Rao, Ripudaman Arora, Ambesh Singh, Prajwal Dange, Nitin M. Nagarkar
Objective—The objective of this study was to systematically assess meta-analyses to determine the lacunae in the literature for PCF following laryngectomy. Methods—Bibliometric analysis were carried out on meta-analyses on PCF after total laryngectomy for laryngeal cancer in the PubMed database. Results—Twenty-four meta-analyses were considered eligible and chosen for analysis. Six meta-analyses (25%) focused on the risk factors for PCF in TL. Four meta-analyses (16.6%) focused on the role of the onlay flap. Four meta-analyses (16.6%) focused on the timing of feed initiation. Three meta-analyses (12.5%) focused on using a stapler for pharyngeal closure. Two meta-analyses focused on types of pharyngeal reconstruction. Other meta-analyses analyzed the use of salivary bypass tubes, the method of pharyngeal closure, organ preservation protocols on PCF, primary and secondary TEP, and the effect of non-surgical treatment on PCF. Conclusion—Despite plenty of published meta-analyses, there is a lack of scrutiny on certain critical aspects of PCF.
目的:本研究的目的是系统地评估meta分析,以确定喉切除术后PCF的文献空白。方法:对PubMed数据库中喉癌全喉切除术后PCF的meta分析进行文献计量学分析。结果:24项荟萃分析被认为符合条件并被选择进行分析。6项荟萃分析(25%)关注TL中PCF的危险因素,4项荟萃分析(16.6%)关注贴壁皮瓣的作用。4项荟萃分析(16.6%)关注于起始喂养的时间。三项荟萃分析(12.5%)集中于使用吻合器进行咽闭合。两项荟萃分析集中于咽重建的类型。其他meta分析分析了唾液旁路管的使用、咽闭合方法、PCF的器官保存方案、原发性和继发性TEP以及非手术治疗对PCF的影响。结论:尽管发表了大量的荟萃分析,但缺乏对PCF某些关键方面的审查。
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引用次数: 0
Reconstruction of Conchal Defects after Chemically Assisted Dissection of Squamous Cell Carcinoma 鳞状细胞癌化学辅助解剖后鼻甲缺损的重建
Pub Date : 2023-09-15 DOI: 10.3390/ohbm4020010
Fabio Piazza, Annamaria Iole Palmeri, Andrea Bacciu, Giuseppe Spriano, Giuseppe Mercante
Background: En block resection of squamous cell carcinoma (SCC) of the concha represents a reconstruction challenge, due to the complex topography and difficult access. Objective: The objective of the present paper is to describe the chemically assisted dissection (CADISS) of SCC originating in the auricular concha and the following reconstruction of the conchal cavity with a post-auricular island flap (PIF), taking care to minimize injury to the donor site. Methods: Twenty-six patients having a diagnosis of SCC of the auricular concha were included in the study. ‘En bloc’ removal of the tumor was accomplished, leaving the adjacent conchal cartilage attached to the tumor and using the CADISS technique to preserve the deep perichondrium. A PIF was used to repair the auricular conchal defect. Results: Flaps were normal at 10 days and at 1-month follow-up. No tumor recurrence was observed. No complications were observed. According to the SCAR scale, good aesthetic outcomes were achieved in all cases, both at the auricular concha and at the donor site. Conclusion: CADISS facilitates the complete removal of the tumor with the preservation of the surrounding normal tissues. A post-auricular island flap can be easily pulled through a post-auricular tunnel to repair the defect and the donor site can be closed primarily.
背景:鼻甲鳞状细胞癌(SCC)的全块切除是一个重建的挑战,由于复杂的地形和难以进入。目的:本文的目的是描述化学辅助解剖(CADISS)起源于耳甲的鳞状细胞癌,以及随后用耳后岛状皮瓣(PIF)重建耳甲腔,注意尽量减少对供体部位的损伤。方法:对26例确诊为耳甲鳞状细胞癌的患者进行研究。完成肿瘤的“整体”切除,留下邻近的耳甲软骨附着在肿瘤上,并使用CADISS技术保存深层软骨膜。采用PIF修复耳廓缺损。结果:皮瓣在10天和1个月的随访中正常。未见肿瘤复发。无并发症发生。根据SCAR评分,在所有病例中,耳甲和供体部位均获得了良好的美学效果。结论:CADISS有利于肿瘤的完全切除,同时保留了周围的正常组织。耳后岛状皮瓣可以很容易地通过耳后通道修复缺损,并且可以主要关闭供区。
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引用次数: 0
Does the Remote Microphone Still Outperform the Pre-Processing Algorithms? A Group Study in Adult Nucleus Recipients 远程麦克风是否仍然优于预处理算法?成人核受体的一组研究
Pub Date : 2023-09-12 DOI: 10.3390/ohbm4020009
Francesco Lazzerini, Luca Baldassari, Adriana Angileri, Luca Bruschini, Stefano Berrettini, Francesca Forli
Despite the evolution of hearing aids and cochlear implants, noisy environments are reportedly still an important hurdle for persons with hearing loss, especially in the process of speech recognition. The development of pre-processing algorithms and the pairing with a wireless device can bring relief to this situation, but it is still under scrutiny whether one or the other is more effective. The purpose of this study was to compare the benefits of speech recognition in a noisy environment by recipients of cochlear implants when using the pre-processing automatic algorithms or when using a wireless microphone. Twenty-nine participants were selected, aged 14 to 83, suffering from sensorineural hearing loss and recipients of cochlear implants for at least 6 months. The proprietary Cochlear Limited SCAN technology uses pre-processing algorithms to attenuate various noises; the wireless device MiniMic2 uses a 2.4 GHz connection to facilitate communications between the recipient and the signal source. Participants were asked to repeat 20 sentences randomly generated by the adaptive Italian Matrix Sentence Test, first while using the SCAN technology and then with the wireless MiniMic2. Both signal and noise were administered through a single loudspeaker set 1 m away from the subject. Significantly better results in speech recognition of noise were achieved with the wireless MiniMic2 when compared to the SCAN technology.
尽管助听器和人工耳蜗不断发展,但据报道,嘈杂的环境仍然是听力损失患者的一个重要障碍,特别是在语音识别过程中。预处理算法的发展和与无线设备的配对可以缓解这种情况,但哪种方法更有效仍在审查中。本研究的目的是比较人工耳蜗植入者在嘈杂环境中使用预处理自动算法和使用无线麦克风进行语音识别的好处。29名参与者被选中,年龄在14岁到83岁之间,患有感音神经性听力损失,接受人工耳蜗植入至少6个月。专有的Cochlear Limited SCAN技术使用预处理算法来衰减各种噪声;无线设备MiniMic2使用2.4 GHz连接,方便接收端和信号源之间的通信。参与者被要求重复自适应意大利语矩阵句子测试随机生成的20个句子,首先使用SCAN技术,然后使用无线MiniMic2。信号和噪声都是通过一个离受试者1米远的扬声器发出的。与SCAN技术相比,无线MiniMic2在噪声语音识别方面取得了明显更好的结果。
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引用次数: 0
Bilateral Vocal Nodules Multidimensional Assessment: Pre- and Post- Speech Language Pathology Intervention 双侧声带小结的多维评估:言语前后语言病理干预
Pub Date : 2023-09-05 DOI: 10.3390/ohbm4020008
Rita Alegria, Susana Vaz-Freitas, Fátima Maia, M. Manso
(1) Background: Vocal fold nodules are bilateral lesions that can have an important negative impact on a person’s job performance, social interaction, and quality of life. This study aims to analyze multidimensional voice evaluation outcomes in a group of patients with bilateral vocal fold nodules who underwent voice therapy. (2) Methods: A retrospective analysis was performed in 42 patients on the following voice evaluations, before and after voice therapy: visual-perceptual (video-laryngostroboscopic evaluation), auditory-perceptual voice analysis based on the GRBAS scale, and aerodynamic voice analysis. Data were collected from January 2001 to December 2019. Data analyses were performed with non-parametric tests (Wilcoxon test) using α = 0.05. (3) Results: The patient average age was 33.6.1 ± 10 years (range 19–60), and 95.2% were female. Voice therapy was delivered by an experienced speech-language pathologist once a week, with an average of 9.8 ± 3 appointments (range 8–17). Vocal fold lesions disappeared in 40.4% of the patients after voice therapy, especially in participants receiving early voice therapy (p = 0.035). When comparing pre- and post-therapy audio-perceptual results, all parameters were improved with statistical significance (p < 0.05) except for the asthenic voice scale. Aerodynamic parameters were all improved but without statistical significance (p > 0.05); (4) Conclusions: Early timing to initiate voice therapy after the onset of symptoms or diagnosis seems to be an important factor for the success of voice therapy (absence of vocal fold nodules).
(1)背景:声带小结是一种双侧病变,会对人的工作表现、社会交往和生活质量产生重要的负面影响。本研究旨在分析双侧声带小结患者接受语音治疗后的多维语音评估结果。(2)方法:回顾性分析42例患者在语音治疗前后的语音评价:视觉-知觉(视频喉频响评价)、基于GRBAS量表的听觉-知觉语音分析、气动语音分析。数据收集时间为2001年1月至2019年12月。资料分析采用非参数检验(Wilcoxon检验),采用α = 0.05。(3)结果:患者平均年龄33.6.1±10岁(19 ~ 60岁),女性占95.2%。语音治疗由经验丰富的语言病理学家提供,每周一次,平均9.8±3次(范围8-17)。40.4%的患者在接受语音治疗后声带病变消失,尤其是早期接受语音治疗的患者(p = 0.035)。对比治疗前后的听觉感知结果,除弱音量表外,其他参数均有显著改善(p < 0.05)。气动参数均有改善,但无统计学意义(p < 0.05);(4)结论:在出现症状或诊断后尽早开始语音治疗似乎是语音治疗成功的重要因素(没有声带结节)。
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引用次数: 0
Effective Vowel Stimuli for Measuring Occlusion Effect in the Pediatric Population 测量小儿人群闭塞效应的有效元音刺激
Pub Date : 2023-08-17 DOI: 10.3390/ohbm4020007
H. Shetty, S. Narasimhan, Sharath Mahanthesh
Past studies have reported that there are higher sound-pressure levels for each vowel in a child’s ear canal than those in adults due to reduced volume and a shorter ear canal. Furthermore, longer vocal tracts are associated with lower formant frequencies, and vice versa. The structural differences in this regard may reflect the difference in the occlusion effect. Thus, the present study compares the sound pressure levels (SPLs) and first formant frequencies of children and adults with normal hearing and determines the best vowel stimulus to assess the occlusion effect. A repeated measures research design was utilized to investigate the best stimulus with which to measure the occlusion effect among children and adults. Group 1 included ten children, and Group 2 comprised ten adults with normal hearing. The SPLs at frequencies between 200 Hz and 1000 Hz for three uttered vowels, with steps of 100 Hz, were measured using a hearing aid analyzer. The recorded vowels were saved in a ‘.wav’ format for formant frequency analysis. Furthermore, a paired comparison method was used to identify the vowel stimulus that most effectively induced the occlusion effect. A significantly higher SPL was observed for children compared to adults for each vowel. The formant frequency F1 value was higher for children than adults for each vowel, constituting a significant finding. In the paired comparison, the occlusion effect was reported to be significantly greater with respect to the vowel /u/ among adults, while it was reported to be greater in relation to the vowel /i/ among children. The vowel /u/ was the best stimulus with which to assess the occlusion effect among adults. The vowel /i/ was the best stimulus with which to assess the occlusion effect among children.
过去的研究表明,儿童耳道中每个元音的声压水平比成人高,这是由于儿童耳道体积较小,耳道较短。此外,较长的声道与较低的峰频率有关,反之亦然。这方面的结构差异可能反映了遮挡效果的差异。因此,本研究比较了听力正常的儿童和成人的声压级(SPLs)和第一形成峰频率,确定了最佳的元音刺激来评估闭塞效果。采用重复测量研究设计来研究儿童和成人中测量闭塞效应的最佳刺激。第1组10名儿童,第2组10名听力正常的成人。使用助听器分析仪测量了三个元音在200 Hz和1000 Hz频率之间的声压差,步长为100 Hz。所记录的元音以“。wav”格式保存,以便进行形成峰频率分析。此外,采用配对比较的方法来识别最有效地诱导闭塞效应的元音刺激。在每个元音上,儿童的声压级明显高于成人。对于每个元音,儿童的形成峰频率F1值高于成人,这是一个重要的发现。在配对比较中,据报道,在成人中,对元音/u/的闭塞效应明显更大,而在儿童中,对元音/i/的闭塞效应更大。元音/u/是评价成人咬合效果的最佳刺激物。元音/i/是评估儿童咬合效果的最佳刺激物。
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引用次数: 0
Next-Generation Auditory Steady-State Responses in Normal-Hearing Adults: A Pilot Test–Retest Reliability Study 正常听力成人的下一代听觉稳态反应:一项先导测试-重测信度研究
Pub Date : 2023-07-10 DOI: 10.3390/ohbm4020006
H. Hamad, Nilesh J. Washnik, Chandan H. Suresh
The Auditory Steady-State Response (ASSR) provides objective and ear-specific information essential for early and appropriate intervention. Test–retest reliability is essential for audiological monitoring. The test–retest reliability of the ASSR has received limited attention. Only a handful of studies found in the literature investigated the test–retest reliability of old-generation ASSR using amplitude or mixed modulated stimuli. However, to our knowledge, no published reports have specifically examined the test–retest reliability of the next-generation ASSR using Chirp family stimuli as implemented in the Interacoustics Eclipse system. This pilot study investigated (a) the test–retest reliability of air conduction (AC) ASSR thresholds across two test sessions and (b) the relationship between differences in ASSR thresholds across two sessions to the residual noise levels in normal-hearing adults. Methods: Fifteen normal-hearing adults (12 females) (30 ears) with an average age of 28 years were recruited for the study. The ASSRs were recorded using a two-channel recording montage. The automatic default stimuli and recording protocol using 90 Hz ASSR, and the accuracy method (p < 0.01) as implemented in the Eclipse system is used to measure ASSR. Results: The study demonstrated strong test–retest reliability for ASSR across frequencies (500 Hz, 1000 Hz, 2000 Hz, and 4000 Hz). Notably, the highest reliability was observed at 500 Hz. The mean test–retest reliability of ASSR was found to be comparable to pure-tone thresholds, but the intra-subject variability is higher for ASSR compared to pure-tone thresholds. Additionally, no significant correlation was found between the difference in ASSR residual noise levels at the threshold and the difference in ASSR thresholds at all tested frequencies. Conclusion: The next-generation system demonstrated strong test–retest reliability across the frequencies examined in this pilot study. Particularly, an improvement in reliability was observed at 500 Hz compared to the old-generation ASSR. This enhancement can be attributed to the utilization of narrow-band CE-chirp stimuli, which generate large amplitude responses, and the implementation of an improved detection paradigm involving multiple harmonics spectral and phase analysis. This pilot study only enrolled adults with normal hearing, and future investigations should include a larger sample size comprising both normal-hearing and hearing-impaired individuals, as well as the pediatric population.
听觉稳态反应(ASSR)为早期和适当的干预提供了客观和耳朵特异性的信息。听力学监测的重测可靠性至关重要。ASSR的重测信度一直受到较少的关注。文献中只有少数研究使用振幅或混合调制刺激研究了老一代ASSR的重测信度。然而,据我们所知,还没有发表的报告专门研究了使用Chirp家族刺激在Interacoustics Eclipse系统中实现的下一代ASSR的测试-重测可靠性。本初步研究调查了(a)两个测试阶段中空气传导(AC) ASSR阈值的测试-重测信度,以及(b)正常听力成人中两个测试阶段中ASSR阈值差异与残余噪声水平之间的关系。方法:招募15名听力正常的成年人(女性12名),平均年龄28岁,30耳。使用双通道蒙太奇录制assr。采用90 Hz ASSR的自动默认刺激和记录方案,以及Eclipse系统中实现的准确度法(p < 0.01)来测量ASSR。结果:该研究显示ASSR在不同频率(500 Hz, 1000 Hz, 2000 Hz和4000 Hz)上具有很强的重测信度。值得注意的是,在500 Hz时观察到最高的可靠性。研究发现,ASSR的平均重测信度与纯音阈值相当,但与纯音阈值相比,ASSR的受试者内部变异性更高。此外,在阈值处ASSR残余噪声水平的差异与所有测试频率下ASSR阈值的差异之间没有发现显著的相关性。结论:新一代系统在本次试点研究中显示了很强的测试重测可靠性。特别是,与老一代ASSR相比,在500 Hz时观察到可靠性的提高。这种增强可以归因于窄带CE-chirp刺激的利用,它产生了大的振幅响应,以及改进的检测范式的实施,包括多谐波频谱和相位分析。这项试点研究只招募了听力正常的成年人,未来的调查应该包括更大的样本量,包括听力正常和听力受损的个体,以及儿科人群。
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引用次数: 1
Risk Factors for Voice Disorders among Fado Singers: A Cross-Sectional Study 法多歌手嗓音障碍的危险因素:一项横断面研究
Pub Date : 2023-06-19 DOI: 10.3390/ohbm4010005
P. Pestana, Susana Vaz-Freitas, M. Manso
Fado is an urban Portuguese musical style rooted in popular culture. Previously found data suggests that Fado singers may have an increased risk of developing voice disorders. (1) Aim: To determine the risk factors for the development of voice disorders among Fado singers. (2) Methods: A cross-sectional study was conducted through the administration of a questionnaire containing questions related to voice disorders in singers. The relationship between personal and social data, musical background, performance demands and habits, vocal health and wellbeing, and strategies to overcome voice problems are reported. Beyond a comprehensive characterization, odds ratios (ORs) and their 95% confidence intervals (CIs) for the association with voice disorders were calculated through univariate and multivariate logistic regression analyses. (3) Results: The significant risk factors for voice disorders were as follows in decreasing order: nose-related disorders; decongestants or antihistamines; oral contraceptives or hormone replacement therapy; previous smoking habits; and vocal fatigue after performances. (4) Conclusion: These activities significantly increased the risk of developing voice disorders. The evidence from this study and the relative low prevalence of self-reported voice disorders suggest that these singers may develop a kind of protective combination of factors beyond the scope of this research.
法多是一种植根于流行文化的葡萄牙城市音乐风格。先前发现的数据表明,法朵歌手患声音障碍的风险可能会增加。(1)目的:探讨法多歌手嗓音障碍发展的危险因素。(2)方法:采用横断面研究方法,对歌手嗓音障碍相关问题进行问卷调查。报告了个人和社会数据、音乐背景、表演需求和习惯、声音健康和福祉以及克服声音问题的策略之间的关系。除了综合表征外,还通过单变量和多变量逻辑回归分析计算了与声音障碍相关的优势比(ORs)及其95%置信区间(CIs)。(3)结果:嗓音障碍的显著危险因素由大到小依次为:鼻相关障碍;减充血药或抗组胺药;口服避孕药或激素替代疗法;既往吸烟习惯;还有表演后的声音疲劳。(4)结论:这些活动明显增加了发生声音障碍的风险。这项研究的证据和自我报告的声音障碍相对较低的患病率表明,这些歌手可能会形成一种保护因素的组合,超出了本研究的范围。
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引用次数: 0
Acoustic Quality of the External Environment: Indications on Questionnaire Structure for Investigating Subjective Perception 外部环境声质量:主观感知调查问卷结构的指示
Pub Date : 2023-06-19 DOI: 10.3390/ohbm4010004
A. Magrini, Gelsomina Di Feo, A. Cerniglia
The subjective judgment on the annoyance produced by noise is always an important tool to complete an investigation, and to find the best way for its reduction. Therefore, acoustic analyses for environmental improvement frequently combine objective measures with subjective surveys to gain a comprehensive understanding of the problem. The technical specification, concerning the “Assessment of noise annoyance by means of social and socio-acoustic surveys”, ISO/TS 15666 (revised in 2021), has represented a basis for these activities since 2003, when it aimed to obtain information about noise annoyance “at home”. The more recent ISO/TS 12913-2 (2018), aimed at soundscape studies, investigations and applications, provides guidelines for conducting social and socio-acoustic surveys to assess noise annoyance and, in particular, it gives detailed indications on data collection and reporting. The indications provided by the technical specifications represent a common guideline for addressing the implementation of a subjective survey in the acoustic field, and to make investigations as comparable as possible. However, they do not cover all the fields of acoustic subjective investigations. Therefore, to make the collection of information from questionnaires more effective, it is useful to have a broader review of the issues that need to be addressed. To support this type of activity, this paper collects and presents relevant observations for the design of subjective survey questionnaires focused on outdoor acoustic quality. Drawing on previous research studies and experiences, it provides a series of observations on the main aspects to be considered in order to structure multipurpose acoustic evaluation questionnaires, including discussion of the general considerations for questionnaire structure, administration methods, population sample characterization, question formulation, and classification. It also deals with specific indications related to acoustic evaluations, such as the characteristics of annoying noise, boundary conditions, subjective feelings, and source features.
对噪音所产生的烦恼进行主观判断,一直是完成调查并找到减少噪音的最佳途径的重要工具。因此,环境改善声学分析往往将客观措施与主观调查相结合,以获得对问题的全面认识。ISO/TS 15666(2021年修订)关于“通过社会和社会声学调查评估噪声干扰”的技术规范,自2003年以来一直代表着这些活动的基础,当时它旨在获取有关“在家”噪声干扰的信息。最新的ISO/TS 12913-2(2018)旨在音景研究、调查和应用,提供了进行社会和社会声学调查以评估噪音烦恼的指南,特别是提供了数据收集和报告的详细说明。技术规范提供的指示是解决声学领域主观调查实施的共同准则,并使调查尽可能具有可比性。然而,它们并没有涵盖声学主观研究的所有领域。因此,为了更有效地收集调查表中的信息,对需要解决的问题进行更广泛的审查是有用的。为了支持这类活动,本文收集并提供了相关的观察结果,用于设计以室外声学质量为重点的主观调查问卷。根据以往的研究和经验,本文对构建多用途声学评价问卷应考虑的主要方面进行了一系列观察,包括对问卷结构、管理方法、总体样本特征、问题制定和分类的一般考虑进行了讨论。它还涉及与声学评估相关的具体指示,例如恼人噪声的特征,边界条件,主观感受和源特征。
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引用次数: 0
The Influence of Cochlear Volume on Temporal Changes of Impedance among Cochlear Implant Patients 耳蜗体积对人工耳蜗患者时间阻抗变化的影响
Pub Date : 2023-05-31 DOI: 10.3390/ohbm4010003
H. Pauna, M. S. A. do Amaral, Daniela S. Fonseca, R. Pessini, Denny M. Garcia, J. Echeverria, A. Guimarães, V. A. R. da Silva, M. Hyppolito
Background: There is evidence that the cochlear volume may influence audiometric thresholds and CI electrodes’ impedance. The aim of the present study was to evaluate the impedance changes over time and correlate them to the residual volume of the cochlea. Methods: An MRI scan was performed via 3-D reconstruction before every surgery to obtain a residual volume for each ear. We performed repeated assessments of electrode impedance, both intra-operatively and post-implant, at the following intervals: 3 months, 6 months, and one year. The same type of perimodiolar array was implanted for each. Results: Thirty-four patients (10 (29.41%) male patients and 24 (70.59%) female patients) were evaluated. Patients received the implants between 2008 and 2017. The mean age of implantation was 13 ± 17.17 years, and the average of hearing thresholds improved after one year of the surgery. The mean cochlear volumes of the implanted ears were 68.16 ± 10.74 mm3 (right ear) and 56.54 ± 13.75 mm3 (left ear). We observed an increase in the basal electrodes’ impedance at the 3rd month. Yet, for the apical electrodes’ impedance, there was a decrease in averaged values. Conclusions: Post-operative impedance measurements were increased when compared to the intraoperatively measured basal values. Newly formed connective tissue is thought to be the cause of the higher impedance values.
背景:有证据表明,耳蜗体积可能影响听力学阈值和CI电极阻抗。本研究的目的是评估阻抗随时间的变化,并将其与耳蜗残余容量相关联。方法:每次手术前通过三维重建进行MRI扫描,以获得每只耳朵的残余体积。我们对电极阻抗进行了重复评估,包括术中和植入后,时间间隔如下:3个月、6个月和1年。分别植入相同类型的磨牙周围阵列。结果:共评价34例患者,其中男性10例(29.41%),女性24例(70.59%)。患者在2008年至2017年期间接受了植入物。平均植入术年龄为13±17.17岁,术后1年平均听力阈值有所改善。耳蜗体积平均右耳为68.16±10.74 mm3,左耳为56.54±13.75 mm3。我们在第3个月观察到基础电极阻抗的增加。然而,对于顶端电极的阻抗,平均值有所下降。结论:与术中测量的基础值相比,术后阻抗测量值增加。新形成的结缔组织被认为是高阻抗值的原因。
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引用次数: 0
Tinnitus, Aural Fullness, and Hearing Loss in a Patient with Acoustic Neuroma and Pituitary Macroadenoma 听神经瘤和垂体大腺瘤患者的耳鸣、听觉充盈和听力损失
Pub Date : 2023-03-27 DOI: 10.3390/ohbm4010002
M. Aldè, L. Pignataro, D. Zanetti
We report the case of a 51-year-old woman with multiple otologic and vestibular symptoms. She presented with two different types of tinnitus in her right ear, vertigo, and fluctuating aural symptoms in the left ear. She also complained of disequilibrium; chronic headache; hyperhidrosis; amenorrhea; insomnia; broadened hands and feet; and widened, thickened, and stubby fingers. The patient underwent careful collection of medical history, otomiscroscopy, pure tone audiometry, tympanometry, reflex threshold measurements, vestibular assessments, blood tests, magnetic resonance imaging (MRI), and cone beam computed tomography (CBTC) of the head. The audiogram showed: (1) a mild low-to-mid frequency conductive hearing loss, and a sharply sloping sensorineural hearing loss above 4000 Hz in the right ear; (2) a mild low-frequency sensorineural hearing loss in the left ear. MRI with 3D FLAIR sequences detected an acoustic neuroma (7.4 mm × 5.2 mm) in the middle-third of the right internal auditory canal, a pituitary macroadenoma (13 mm × 10 mm × 10 mm) and left saccular hydrops. The CBCT scan documented an outbreak of otosclerosis (3 mm) around the fissula ante fenestram in the right ear. Therefore, acoustic neuroma (right ear), growth hormone-secreting macroadenoma of the pituitary gland, Menière’s disease (left ear), and otosclerosis (right ear) were diagnosed/strongly suspected. A watch-and-wait strategy was adopted for acoustic neuroma and otosclerosis, while transsphenoidal surgery was successfully performed to remove the pituitary macroadenoma. This case report confirms that multiple otologic disorders can occur simultaneously in the same patient, requiring prompt audiological and imaging evaluations.
我们报告的情况下,51岁的妇女多发性耳科和前庭症状。她的右耳有两种不同类型的耳鸣,眩晕,左耳有波动的听觉症状。她还抱怨失衡;慢性头痛;多汗;闭经;失眠;双手和双脚张开;手指变宽、变粗、变短。患者接受了详细的病史收集、耳镜检查、纯音听力学、鼓室测量、反射阈值测量、前庭评估、血液检查、磁共振成像(MRI)和头部锥束计算机断层扫描(CBTC)。听力图显示:(1)右耳为轻度中低频传导性听力损失,4000 Hz以上为陡坡性感音神经性听力损失;(2)左耳轻度低频感音神经性听力损失。MRI 3D FLAIR序列示右侧内耳道中段1个听神经瘤(7.4 mm × 5.2 mm), 1个垂体大腺瘤(13 mm × 10 mm × 10 mm),左侧囊性积液。CBCT扫描显示右耳前窗裂周围爆发耳硬化(3mm)。因此,诊断为听神经瘤(右耳)、垂体生长激素分泌大腺瘤、meniires病(左耳)和耳硬化(右耳)/强烈怀疑。听神经瘤和耳硬化采用观察等待策略,经蝶窦手术成功切除垂体大腺瘤。本病例报告证实,多种耳科疾病可同时发生在同一患者,需要及时的听力学和影像学评估。
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引用次数: 1
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Journal of otorhinolaryngology, hearing and balance medicine
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