Liu Guoyuan, Liu Zhijin, Ning Changxiu, Wang Chengquan, Han Jiajun
{"title":"An observation on the mimic ecology of the oncomelania hupensis in three-gorge-reservoir areas","authors":"Liu Guoyuan, Liu Zhijin, Ning Changxiu, Wang Chengquan, Han Jiajun","doi":"10.1007/BF02888467","DOIUrl":"https://doi.org/10.1007/BF02888467","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02888467","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52209958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Workshop Announcement","authors":"Y. Jing","doi":"10.1007/BF02895594","DOIUrl":"https://doi.org/10.1007/BF02895594","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02895594","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52318255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Dong, Zuohua Feng, Shiqiao Ye, Guimei Zhang, Zhang Hui, Huang Bo, Xiao Hui
{"title":"Construction and expression of eukaryotic expressing vector pCH510 of polypeptide CH50 and its chemotaxis and antitumor function byin vivo transfection","authors":"Li Dong, Zuohua Feng, Shiqiao Ye, Guimei Zhang, Zhang Hui, Huang Bo, Xiao Hui","doi":"10.1007/BF02888022","DOIUrl":"https://doi.org/10.1007/BF02888022","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02888022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52207077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An analysis on the diagnostic values of transcranial Doppler and angiography in transient ischemic attack","authors":"J. Yaping, Hu Jingqiong, G. Qiong","doi":"10.1007/BF02888066","DOIUrl":"https://doi.org/10.1007/BF02888066","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02888066","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52208509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ding Qingqing, W. Zaide, C. Xiaoping, A. H. Musa, H. Junbo, Zhang Yongqiang
{"title":"Gene therapy of HSV-TK transferred by the EBV based expression vector on experimental hepatocellular carcinoma","authors":"Ding Qingqing, W. Zaide, C. Xiaoping, A. H. Musa, H. Junbo, Zhang Yongqiang","doi":"10.1007/BF02888074","DOIUrl":"https://doi.org/10.1007/BF02888074","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02888074","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52208597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A notice inviting subscription","authors":"","doi":"10.1007/BF02888121","DOIUrl":"https://doi.org/10.1007/BF02888121","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02888121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52208930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gao Chong-rong, Jin Shi’ao, Dai Jin-zhen, Ma Zi-cheng
{"title":"The anesthetic management of allo-pancreatic transplantation","authors":"Gao Chong-rong, Jin Shi’ao, Dai Jin-zhen, Ma Zi-cheng","doi":"10.1007/BF02888454","DOIUrl":"https://doi.org/10.1007/BF02888454","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02888454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52209933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zheng Jianfeng, Hong Shuyun, Chen Siyuan, Chen Jing-chun, Zhang Changgong
{"title":"Effects of huangdan capsule on plasma cGMP and ANP in rats with chronic renal failure","authors":"Zheng Jianfeng, Hong Shuyun, Chen Siyuan, Chen Jing-chun, Zhang Changgong","doi":"10.1007/BF02888470","DOIUrl":"https://doi.org/10.1007/BF02888470","url":null,"abstract":"","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02888470","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52209996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In order to provide a new method for treating proliferative vitreoretinopathy (PVR), the effects of anti-proliferation and apoptosis induction of inhibitors of telomerase and heat shock protein 90 (Hsp90) on the cultured retinal pigment epithelial (RPE) cells were investigated. The rate of apoptosis cells was measured by using TUNEL on the cultured RPE cells, the co-cultured RPE cells with inhibitor of telomerase (camptothecin) or the co-cultured RPE cells with inhibitor of Hsp90 (geldanamycin). The cell proliferation status was measured in the above three groups by using MTT method. The rate of apoptosis in the RPE cells co-cultured with camptothecin or geldanamycin was increased remarkably (P < 0.05). MTT showed the rate of growth inhibition was 8.4%, 32.3% and 72.3% at the concentrations of camptothecin 1 mumol/L, 5 mumol/L, 10 mumol/L, respectively, and 6.5%, 30.9%, 71.9% at the concentrations of geldanamycin 1 mumol/L, 5 mumol/L, 10 mumol/L, respectively. It was concluded that telomerase and Hsp90 can promote the proliferation of the cultured RPE cells, while the inhibitor of them can induce apoptosis and inhibit the growth of the RPE cells.
{"title":"The anti-proliferative effect of inhibitor of telomerase on cultured retinal pigment epithelial cells.","authors":"Y Xiang, S Zeng","doi":"10.1007/BF02888090","DOIUrl":"10.1007/BF02888090","url":null,"abstract":"<p><p>In order to provide a new method for treating proliferative vitreoretinopathy (PVR), the effects of anti-proliferation and apoptosis induction of inhibitors of telomerase and heat shock protein 90 (Hsp90) on the cultured retinal pigment epithelial (RPE) cells were investigated. The rate of apoptosis cells was measured by using TUNEL on the cultured RPE cells, the co-cultured RPE cells with inhibitor of telomerase (camptothecin) or the co-cultured RPE cells with inhibitor of Hsp90 (geldanamycin). The cell proliferation status was measured in the above three groups by using MTT method. The rate of apoptosis in the RPE cells co-cultured with camptothecin or geldanamycin was increased remarkably (P < 0.05). MTT showed the rate of growth inhibition was 8.4%, 32.3% and 72.3% at the concentrations of camptothecin 1 mumol/L, 5 mumol/L, 10 mumol/L, respectively, and 6.5%, 30.9%, 71.9% at the concentrations of geldanamycin 1 mumol/L, 5 mumol/L, 10 mumol/L, respectively. It was concluded that telomerase and Hsp90 can promote the proliferation of the cultured RPE cells, while the inhibitor of them can induce apoptosis and inhibit the growth of the RPE cells.</p>","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9663970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To investigate the clinical significance of magnetic resonance imaging (MRI) of bone marrow in patients with acute leukemia, the femoral and pelvic marrow were evaluated by using MRI with a T1-weighted spin-echo (SE) method and a short T1 inversion recovery (STIR) technique. Normal bone marrow examination was performed with coronal T1-weighted MRI of pelvis and femurs, and showed persistent red marrow. There was a bright signal of fatty marrow in the femoral epiphyses and apophyses. MRI pattern of bone marrow in the 54 cases of acute leukemia showed abnormal signal patterns of femoral and pelvic marrow: (1) grade I (n = 4), (2) grade II (n = 11), (3) grade III (n = 8), (4) grade IV (n = 17), and (5) graded V (n = 14). Leukemic cells had infiltration onseted by red marrow in adult patients with leukemia. The marrow of femur had infiltration from diaphysis to epiphysis, and to femoral head and greater trochanter. The lower grades (grade IV, V) of leukemic marrow supported the diagnosis of AML in MRI, which achieved higher complete remission. The adult patients with ALL had higher grades (grade I-III) in MRI. Our findings indicated that MRI of femoral marrow is an important tool for accurate diagnosis and management of patients with leukemia that may function as an adjunct to bone marrow aspiration and biopsy. The pattern of MRI in patients with newly diagnosed leukemia predicted the prognosis and CR of leukemia.
为了研究急性白血病患者骨髓磁共振成像（MRI）的临床意义，我们采用T1加权自旋回波（SE）方法和短T1反转恢复（STIR）技术对股骨和骨盆骨髓进行了磁共振成像评估。骨盆和股骨的冠状 T1 加权核磁共振检查显示骨髓正常，骨髓呈持续的红色。股骨骺端和远端有脂肪骨髓的亮信号。54 例急性白血病患者的骨髓 MRI 显示股骨和骨盆骨髓的异常信号模式：(1) I 级（4 例），(2) II 级（11 例），(3) III 级（8 例），(4) IV 级（17 例），(5) V 级（14 例）。成年白血病患者的红骨髓开始出现白血病细胞浸润。股骨髓从干骺端到骨骺端，以及股骨头和大转子都有浸润。白血病骨髓的较低分级（IV 级、V 级）支持了核磁共振成像对急性髓细胞白血病的诊断，而急性髓细胞白血病的完全缓解率较高。成人 ALL 患者的 MRI 分级更高（I-III 级）。我们的研究结果表明，股骨髓核磁共振成像是准确诊断和治疗白血病患者的重要工具，可作为骨髓穿刺和活检的辅助手段。新诊断的白血病患者的核磁共振成像模式可预测白血病的预后和CR。
{"title":"Clinical significance of magnetic resonance imaging of bone marrow in patients with leukemia.","authors":"J Wang, X Zhang, J Niu","doi":"10.1007/BF02886443","DOIUrl":"10.1007/BF02886443","url":null,"abstract":"<p><p>To investigate the clinical significance of magnetic resonance imaging (MRI) of bone marrow in patients with acute leukemia, the femoral and pelvic marrow were evaluated by using MRI with a T1-weighted spin-echo (SE) method and a short T1 inversion recovery (STIR) technique. Normal bone marrow examination was performed with coronal T1-weighted MRI of pelvis and femurs, and showed persistent red marrow. There was a bright signal of fatty marrow in the femoral epiphyses and apophyses. MRI pattern of bone marrow in the 54 cases of acute leukemia showed abnormal signal patterns of femoral and pelvic marrow: (1) grade I (n = 4), (2) grade II (n = 11), (3) grade III (n = 8), (4) grade IV (n = 17), and (5) graded V (n = 14). Leukemic cells had infiltration onseted by red marrow in adult patients with leukemia. The marrow of femur had infiltration from diaphysis to epiphysis, and to femoral head and greater trochanter. The lower grades (grade IV, V) of leukemic marrow supported the diagnosis of AML in MRI, which achieved higher complete remission. The adult patients with ALL had higher grades (grade I-III) in MRI. Our findings indicated that MRI of femoral marrow is an important tool for accurate diagnosis and management of patients with leukemia that may function as an adjunct to bone marrow aspiration and biopsy. The pattern of MRI in patients with newly diagnosed leukemia predicted the prognosis and CR of leukemia.</p>","PeriodicalId":73995,"journal":{"name":"Journal of Tongji Medical University = Tong ji yi ke da xue xue bao","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22205739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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