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The Continued Misadventures of Intentional C4 Ingestion: A Case Cluster. 故意摄入C4的持续事故:一组病例。
Seth Brown, Nathan Davidson, Brandon M Carius

Several published case reports describe the intentional ingestion of cyclotrimethylenetrinitramine, more commonly referred to as Composite-4 (C4), by military personnel. This putty-like explosive material, used for breaching operations, can produce euphoric effects through polyisobutylene; however, the additional ingredient of Research Department Explosive (RDX), or "Cyclonite," can cause significant central nervous system disruption resulting in seizures. We report a unique case cluster of active-duty personnel with intentional C4 ingestion and wide-ranging symptoms, including seizures. Unit personnel discovered this cluster after progressive patient presentations. This report illustrates the spectrum of C4 ingestion effects, as well as the need for investigation to ensure prompt medical evaluation and management of those suspected of consumption.

一些已发表的病例报告描述了军事人员故意摄入环三甲基三硝胺(通常称为C4)的情况。这种类似于腻子的爆炸物,用于爆破作业,可以通过聚异丁烯产生欣快效果;然而,研究部门炸药(RDX)的额外成分,或“旋风石”,会导致严重的中枢神经系统紊乱,导致癫痫发作。我们报告一个独特的病例集群现役人员有意C4摄入和广泛的症状,包括癫痫发作。单位人员在病人出现进展后发现了这个集群。本报告说明了C4摄入影响的范围,以及调查的必要性,以确保及时对疑似食用者进行医疗评估和管理。
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引用次数: 0
Accuracy of Needle Thoracostomy Site Selection among US Army Medics. 美国陆军军医胸廓穿刺位置选择的准确性。
Rachel C Rodriguez, Clifford Sandoval, Matthew Perdue, Jonathan Monti, Jerimiah Walker

Background: Tension pneumothorax is a prominent cause of potentially survivable death on the battlefield. Field management for suspected tension pneumothorax is immediate needle thoracostomy (NT). Recent data noted higher NT success rates and ease of insertion at the fifth intercostal space, anterior axillary line (5th ICS AAL), leading to an amendment of the Committee on Tactical Combat Casualty Care recommendations on managing suspected tension pneumothorax to include the 5th ICS AAL as a viable alternative site for NT placement. The objective of this study was to assess the overall accuracy, speed, and ease of NT site selection and compare these outcomes between the second intercostal space, midclavicular line (2nd ICS MCL) and 5th ICS AAL among a cohort of Army medics.

Methods: We designed a prospective, observational, comparative study and recruited a convenience sample of US Army medics from a single military installation to localize and mark the anatomic location where they would perform an NT at the 2nd ICS MCL and 5th ICS AAL on 6 live human models. The marked site was compared for accuracy to an optimal site predetermined by investigators. We assessed the primary outcome of accuracy via concordance with the predetermined NT site location at the 2nd ICS MCL and 5th ICS MCL. Secondarily, we compared time to final site marking and the influence of model body mass index (BMI) and gender on accuracy of selection between sites.

Results: A total of 15 participants performed 360 NT site selections. We found a significant difference between participants' ability to accurately target the 2nd ICS MCL compared to the 5th ICS AAL (42.2% versus 10% respectively, p is less than 0.001). The overall accuracy rate among all NT site selections was 26.1%. We also found a significant difference in time-to-site identification between the 2nd ICS MCL and 5th ICS AAL in favor of the 2nd ICS MCL (median [IQR] 9 [7.8] seconds versus 12 [12] seconds, p is less than 0.001).

Conclusions: US Army medics may be more accurate and faster at identifying the 2nd ICS MCL when compared to the 5th ICS AAL. However, overall site selection accuracy is unacceptably low, highlighting an opportunity to enhance training for this procedure.

背景:在战场上,紧张性气胸是潜在的生存死亡的主要原因。现场处理疑似张力性气胸是立即穿刺开胸术(NT)。最近的数据表明,在第5肋间隙、腋前线(第5 ICS AAL)置入NT成功率更高,也更容易,这导致战术战斗伤亡护理委员会对治疗疑似紧张性气胸的建议进行了修订,将第5 ICS AAL作为NT放置的可行替代位置。本研究的目的是评估NT位置选择的总体准确性、速度和便利性,并比较一群陆军医务人员在第2肋间隙、锁骨中线(第2 ICS MCL)和第5 ICS AAL之间的结果。方法:我们设计了一项前瞻性、观察性、比较性的研究,并从一个军事设施中招募了方便的美国陆军医务人员,以定位和标记他们将在第2 ICS MCL和第5 ICS AAL对6个活体人体模型进行NT的解剖位置。标记的地点是比较准确性的最佳地点预定的调查员。我们通过与预定的NT位置在第2和第5 ICS MCL的一致性来评估准确性的主要结局。其次,我们比较了时间到最终的位点标记,以及模型体重指数(BMI)和性别对位点选择准确性的影响。结果:共有15名参与者进行了360次NT部位选择。我们发现,与第5次ICS AAL相比,参与者准确瞄准第2次ICS MCL的能力存在显著差异(分别为42.2%和10%,p < 0.001)。所有NT位点选择的总体准确率为26.1%。我们还发现,第2次ICS MCL和第5次ICS AAL在到达位点的时间上存在显著差异,第2次ICS MCL更有利(中位数[IQR] 9[7.8]秒对12[12]秒,p < 0.001)。结论:与第5次ICS AAL相比,美国陆军医务人员在识别第2次ICS MCL时可能更准确、更快。然而,总体的选址准确性低得令人无法接受,这凸显了加强该程序培训的机会。
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引用次数: 0
Platelet-Rich Plasma Improves Strength and Speed of Recovery in an Active-Duty Soldier with Isolated Injury to the Lateral Collateral Ligament of the Knee: A Case Report. 富血小板血浆提高孤立性膝关节外侧副韧带损伤的现役士兵的力量和恢复速度:一例报告。
C Drake Castle, Colin M Dunderdale, Jeanne C Patzkowski, Brandon M Carius

Ligamentous injuries of the knee occur in the military, but constitute an overwhelmingly disproportionate number of medical discharges, which can be due to prolonged recovery through traditional use of physical therapy (PT) and other non-operative modalities. The use of platelet-rich plasma (PRP) may substantially increase the speed of recovery and patient outcomes but is little explored for less common isolated ligamentous injuries, such as the lateral collateral ligament, especially in active-duty populations. We describe the use of PRP in a young, otherwise healthy active-duty male to treat an isolated LCL injury with significant positive outcomes. These findings support consideration for early use of PRP in similar cases to improve recovery timelines and aid in return to duty.

膝关节韧带损伤在军队中也有发生,但由于采用传统的物理治疗和其他非手术方式,恢复时间较长,因此在医疗出院中所占比例极高。富血小板血浆(PRP)的使用可能会大大提高恢复速度和患者的预后,但很少探索不太常见的孤立韧带损伤,如外侧副韧带,特别是在现役人群中。我们描述了在一个年轻的,健康的现役男性中使用PRP治疗孤立的LCL损伤,并取得了显著的积极结果。这些发现支持考虑在类似病例中早期使用PRP,以改善恢复时间并帮助重返工作岗位。
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引用次数: 0
Medic and Portable Pulse Oximeter Respiratory Rate Measurement Comparison to Waveform Capnography: A Prospective, Observational Study. 医用和便携式脉搏血氧仪呼吸率测量与波形心电图的比较:一项前瞻性观察研究。
Hyun J Yi, Lisa M Jin, Drew Long, Brandon M Carius, Brian J Ahern

Background: The second leading cause of preventable battlefield death involves airway management. Tactical combat casualty care (TCCC) guidelines emphasize combat casualty airway, breathing and respiratory evaluation, including respiratory rate (RR) measurement. The current standard of practice for the US Army medics is to measure the RR by manual counting. Manual counting methods are operator-dependent, and medics face situational stressors limiting accurate measurement of RR in combat settings. To date, no published studies evaluate alternate methods of RR measurement by medics. The purpose of this study is to compare RR assessment by medics against waveform capnography and commercial finger pulse oximeters with continuous plethysmography.

Materials and methods: We conducted a prospective, observational study to compare Army medic RR assessments against plethysmography and waveform capnography RR. Assessments were performed prior to and following exertion at 30 and 60 seconds with both the pulse oximeter (NSN 6515-01-655-9412) and defibrillator monitor (NSN 6515-01-607-8629), followed by end-user surveys.

Results: Of the 40 medics enrolled over a 4-month period, most were male (85%), and reported between less than 5 years of military and medical experience. The mean manual RR reported by medics at rest did not significantly differ from waveform capnography (14.05 versus 13.98, p is equal to 0.523); however, mean manual RR reported by medics on post-exertional subjects was significantly lower than waveform capnography (25.62 versus 29.77, p is less than 0.001). Time to medic-obtained RR was slower than the pulse oximeter (NSN 6515-01-655-9412) both at rest (-7.37 seconds, p is less than 0.001) and at exertion (-6.50 seconds, p is less than 0.001). While the mean difference in RR between the pulse oximeter (NSN 6515-01-655-9412) and waveform capnography in models at rest at 30 seconds was statistically significant (-1.38, p is less than 0.001). There was no overall statistically significant differences in RR between the pulse oximeter (NSN 6515-01-655-9412) and waveform capnography in models at exertion at 30 seconds and at rest and exertion at 60 seconds.

Conclusion: Resting RR measurement did not differ significantly; however, medic-obtained RR considerably deviated from both pulse oximeters and waveform capnography at elevated rates. Existing commercial pulse oximeters with RR plethysmography do not differ significantly from waveform capnography and should be investigated further for consideration in fielding across the force for RR assessment.

背景:可预防性战场死亡的第二大原因涉及气道管理。战术战斗伤亡护理(TCCC)指南强调战斗伤员气道、呼吸和呼吸评估,包括呼吸率(RR)测量。美国陆军医务人员目前的做法标准是通过人工计数来测量RR。手动计数方法依赖于操作人员,并且在战斗环境中,医务人员面临的情境压力因素限制了RR的准确测量。到目前为止,还没有发表的研究评估医生测量RR的替代方法。本研究的目的是比较医生对波形血糖仪和商用手指脉搏血氧仪进行的RR评估。材料和方法:我们进行了一项前瞻性观察性研究,将陆军医务人员的RR评估与体积脉搏波和波形血流描记RR进行比较。使用脉搏血氧仪(NSN 6515-01-655-9412)和除颤器监测器(NSN 6515-01-607-8629)在运动前和运动后30秒和60秒进行评估,然后进行最终用户调查。结果:在4个月期间招募的40名医务人员中,大多数是男性(85%),报告的军事和医疗经验少于5年。医务人员静止时报告的平均手动RR与波形心电图无显著差异(14.05 vs 13.98, p = 0.523);然而,医务人员报告的运动后受试者的平均手工RR显著低于波形心电图(25.62比29.77,p < 0.001)。静息时(-7.37秒,p < 0.001)和运动时(-6.50秒,p < 0.001)到达医学上获得的RR的时间都比脉搏血氧仪(NSN 6515-01-655-9412)慢。而脉搏血氧仪(NSN 6515-01-655-9412)与波形血糖在30秒静息时的平均RR差异有统计学意义(-1.38,p < 0.001)。脉搏血氧仪(NSN 6515-01-655-9412)与波形血氧仪在运动30秒和休息运动60秒时的RR总体上无统计学差异。结论:静息RR测量无显著性差异;然而,在较高的速率下,医学上获得的RR与脉搏血氧仪和波形血糖仪都有相当大的偏差。现有的商用脉搏血氧仪与脉搏波形血氧仪没有明显的区别,应该进一步研究,以便在整个部队中进行脉搏血氧率评估。
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引用次数: 0
Admissions Interviews: How History Can Pave the Way Toward a Holistic Future in Military PA Program Admissions and Hiring. 招生面试:历史如何为军事PA项目招生和招聘的整体未来铺平道路。
Anne Wildermuth

Admissions processes for graduate health professions, including physician assistant (PA) and medical school, were built over time through trial and error. Admissions process research was not common until the early 1990s, and it seemingly began because the system of admitting applicants solely on the basis of the highest academic metrics resulted in unacceptable attrition rates. Recognizing interpersonal attributes were unique from academic metrics and critical to success in medical education, admissions interviews were added as a component of the admissions process and have since become nearly ubiquitous for medical and PA applicants. Understanding the history of admissions interviews informs ways to optimize admissions processes for the future. The PA profession was originally comprised entirely of military veterans with extensive medical training during their service; the number of service members and veterans matriculating has significantly decreased and is not reflective of the percentage of veterans in the US. Most PA programs receive applications in excess of available seats; yet, based on the 2019 PAEA Curriculum Report, the all-cause attrition rate is 7.4%. Given the large pool of applicants available to select from, it is valuable to identify students who will succeed and graduate. This is especially critical for the Interservice Physician Assistant Program, the US Military's PA program, to optimize force readiness by ensuring sufficient PAs are available. Utilizing a holistic admissions process, considered best practice in admissions, is an evidence-based way to decrease attrition and support increased diversity, including increasing the number of veterans becoming PAs, by considering the breadth of an applicant's life experiences, personal attributes, and academic metrics. The outcomes of admissions interviews are high-stakes for the program and applicants, as they are often the final step prior to admissions decisions. Additionally, there is considerable overlap between the principles of admissions interviews and job interviews, the latter of which may occur as a military PA's career unfolds and they are considered for special assignments. Though numerous different interview modalities exist, multiple mini-interviews (MMI) are highly-structured, effective, and are supportive of a holistic admissions approach. Through examining historical admissions trends, identifying a modern way to select applicants through holistic admissions can support decreased student deceleration and attrition and increased diversity, optimizing force readiness and supporting the success of the PA profession into the future.

包括医师助理(PA)和医学院在内的卫生专业研究生的录取程序,是经过长期的试错而建立起来的。直到20世纪90年代初,对招生过程的研究才开始普及,它的出现似乎是因为仅仅根据最高的学术指标录取申请人的制度导致了不可接受的流失率。认识到人际关系属性与学术指标不同,对医学教育的成功至关重要,招生面试被增加为招生过程的一个组成部分,从此成为医学和研究生申请者几乎无处不在的地方。了解招生面试的历史有助于优化未来的招生过程。私人助理职业最初完全由退伍军人组成,在服役期间接受过广泛的医疗培训;服役人员和退伍军人的入学人数大幅减少,这并不能反映美国退伍军人的比例。大多数PA项目收到的申请超过了可用座位;然而,根据2019年PAEA课程报告,全因流失率为7.4%。考虑到有大量的申请者可供选择,确定哪些学生会成功并毕业是很有价值的。这对于跨军种医师助理项目(美国军方的PA项目)来说尤其重要,通过确保足够的PA可用来优化部队战备状态。通过考虑申请人的生活经历、个人属性和学术指标的广度,利用整体招生过程被认为是招生中的最佳实践,是一种以证据为基础的方法,可以减少人员流失,支持增加多样性,包括增加退伍军人成为助理的数量。招生面试的结果对项目和申请人来说都是至关重要的,因为面试通常是录取决定之前的最后一步。此外,在招生面试和工作面试的原则之间有相当大的重叠,后者可能发生在军事助理的职业生涯展开时,他们被认为是特殊任务。虽然存在许多不同的面试方式,但多个迷你面试(MMI)是高度结构化的,有效的,并且支持整体录取方法。通过研究历史招生趋势,确定一种通过整体招生来选择申请人的现代方式,可以减少学生的减速和流失,增加多样性,优化部队准备,并支持私人助理职业在未来的成功。
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引用次数: 0
Impact of a Novel Biplane User Interface on Ultrasound-Guided Vascular Access Performance: A Prospective, Randomized, Crossover Study. 一种新型双翼用户界面对超声引导血管通路性能的影响:一项前瞻性、随机、交叉研究。
Nicholas A Jones, Cecil J Simmons, Philip Castañeda, Brandon M Carius, Aaron J Cronin, Jonathan Monti

Background: Controversy exists regarding the optimal methods of employing ultrasound to enhance vascular access. A novel user interface which dynamically displays transverse (short) and longitudinal (long) planes simultaneously was developed to optimize ultrasound-guided vascular access. This study aimed to assess the impact of this novel biplane axis technology on central venous access performance.

Methods: Eighteen volunteer emergency medicine resident physicians and physician assistants were recruited from a single center to participate in this prospective, randomized crossover study. Following a brief instructional video, participants were randomized to perform ultrasound-guided vascular access using either short-axis or biplane axis approaches first, followed by the opposite technique following a brief washout period. Time to cannulation was the primary outcome measure. Secondary outcome measures included success rate, posterior wall and arterial puncture rates, time to scout, number of attempts, number of needle redirections, participant cannulization and visualization confidence, and interface preference.

Results: Short-axis imaged approach was associated with a significantly shorter time to cannulation (34.9 seconds versus 17.6, p is less than 0.001) and time to scout (30 versus 49 seconds, p is equal to 0.008) when compared to biplaneaxis imaging approach. No significant differences were noted when comparing first pass success, number of attempts, number of redirections, and posterior wall and arterial wall puncture. Participants' cannulation/visualization confidence and axis preference both favored the short-axis imaging approach.

Conclusion: Further studies are needed to assess the clinical value of novel biplane axis ultrasound imaging in the performance of ultrasound-guided procedures.

背景:关于超声增强血管通路的最佳方法存在争议。为了优化超声引导血管通路,开发了一种同时动态显示横向(短)和纵向(长)平面的新型用户界面。本研究旨在评估这种新型双翼轴技术对中心静脉通路性能的影响。方法:从单个中心招募18名急诊住院医师和医师助理志愿者参与这项前瞻性、随机交叉研究。在观看了一段简短的教学视频后,参与者被随机分配,首先使用短轴或双翼轴入路进行超声引导的血管通路,然后在短暂的洗脱期后使用相反的技术。插管时间为主要观察指标。次要结局指标包括成功率、后壁和动脉穿刺率、探查时间、尝试次数、针头重定向次数、参与者插管和可视化信心以及界面偏好。结果:与双平轴成像入路相比,短轴成像入路的插管时间(34.9秒比17.6秒,p < 0.001)和侦察时间(30秒比49秒,p = 0.008)显著缩短。当比较第一次通过成功率、尝试次数、重新定向次数、后壁和动脉壁穿刺时,没有发现显著差异。受试者的插管/可视化信心和轴向偏好均倾向于短轴成像方法。结论:新型双翼轴超声成像在超声引导手术中的临床应用价值有待进一步研究。
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引用次数: 0
A Review of Intermittent Fasting as a Treatment for Type 2 Diabetes Mellitus. 间歇性禁食治疗2型糖尿病的研究进展
Derek T Silver, Timothy B Pekari

Background: Introduction: The purpose of this review is to explore intermittent fasting (IF) versus continuous energy restriction as a treatment of Type 2 Diabetes Mellitus (T2DM). The precursor to diabetes is obesity, which currently threatens the Department of Defense's ability to retain and recruit adequate service members. Intermittent fasting may be an adjunct for prevention of obesity and diabetes in the armed forces.

Objectives: Weight loss and lifestyle modification are long-standing treatments for T2DM. The objective of this review is to compare IF to continuous energy restriction.

Methods: PubMed was searched from August 2013 to March 2022 for systematic reviews, randomized controlled trials, clinical trials, and case series. Inclusion criteria were studies which monitored HbA1C, fasting glucose levels, diagnosis of T2DM, ages 18-75, and a body mass index (BMI) greater than or equal to 25 kg/m2. Eight articles met these criteria and were selected. These 8 articles were separated into Categories A and B for this review. Category A includes randomized controlled trials (RCTs), and Category B consists of pilot studies and clinical trials.

Results: Intermittent fasting proved to have commensurate decreases in HbA1C and BMI compared to the control group, but not to a statistically significant degree. It cannot be said that IF is better than continuous energy restriction.

Conclusion: More research is needed on this topic as 1 in 11 people suffer from T2DM. The benefits of IF are apparent, but there is not enough breadth of research available to affect clinical guidelines.

背景:简介:本综述的目的是探讨间歇性禁食(IF)与持续能量限制作为2型糖尿病(T2DM)的治疗方法。糖尿病的先兆是肥胖,它目前威胁着国防部留住和招募足够的服务人员的能力。间歇性禁食可能是预防军队肥胖和糖尿病的辅助手段。目的:减肥和改变生活方式是T2DM的长期治疗方法。本综述的目的是比较IF和连续能量限制。方法:检索PubMed 2013年8月至2022年3月的系统评价、随机对照试验、临床试验和病例系列。纳入标准是监测HbA1C、空腹血糖水平、T2DM诊断、年龄18-75岁、体重指数(BMI)大于或等于25 kg/m2的研究。8篇文章符合这些标准并入选。本综述将这8篇文章分为A类和B类。A类包括随机对照试验(rct), B类包括试点研究和临床试验。结果:与对照组相比,间歇性禁食证明HbA1C和BMI有相应的降低,但没有统计学意义。不能说IF比持续的能量限制更好。结论:由于每11个人中就有1人患有2型糖尿病,因此需要对此进行更多的研究。干扰素的好处是显而易见的,但目前还没有足够广泛的研究来影响临床指南。
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引用次数: 0
Successful Surgical Airway Performance in the Combat Prehospital Setting: A Qualitative Study of Experienced Military Prehospital Providers. 成功的手术气道性能在战斗院前设置:有经验的军事院前提供者的定性研究。
Timothy B Pekari, John L Melton, Ronald M Cervero, Anita Samuel

Introduction: Military first responders are in a unique category of the healthcare delivery system. They range in skill sets from combat medic and corpsman to nurses, physician assistants, and occasionally, doctors. Airway obstruction is the second leading cause of preventable battlefield death, and the decision for intervention to obtain an airway depends on the casualty's presentation, the provider's comfort level, and the available equipment, among many other variables. In the civilian prehospital setting cricothyroidotomy (cric) success rates are over 90%, but in the US military combat environment success rates range from 0-82%. This discrepancy in success rates may be due to training, environment, equipment, patient factors and/or a combination of these. Many presumed causes have been assumed to be the root of the variability, but no research has been conducted evaluating the first-person point of view. This research study is focused on interviewing military first responders with real-life combat placement of a surgical airway to identify the underlying influences which contribute to their perception of success or failure.

Materials and methods: We conducted a qualitative study with in-depth semi-structured interviews to understand participants' real-life cric experiences. The interview questions were developed based on the Critical Incident Questionnaire. In total, there were 11 participants-4 retired military and 7 active-duty service members.

Results: Nine themes were generated from the 11 interviews conducted. These themes can be categorized into 2 groups: factors internal to the provider, which we have called intrinsic influences, and factors external to the provider, which we call extrinsic influences. Intrinsic influences include personal well-being, confidence, experience, and decision-making. Extrinsic influences include training, equipment, assistance, environment, and patient factors.

Conclusions: This study revealed practitioners in combat settings felt the need to train more frequently in a stepwise fashion while following a well-understood airway management algorithm. More focus must be on utilizing live tissue with biological feedback, but only after anatomy and geospatial orientation are well understood on models, mannequins, and cadavers. The equipment utilized in training must be the equipment available in the field. Lastly, the focus of the training should be on scenarios which stress the physical and mental capabilities of the providers. A true test of both self-efficacy and deliberate practice is forced through the intrinsic and extrinsic findings from the qualitative data. All of these steps must be overseen by expert practitioners. Another key is providing more time to focus on medical skills development, which is critical to overall confidence and overcoming hesitation in the decision-making process. This is even more specific to

简介:军事第一响应者在医疗保健服务系统中是一个独特的类别。他们的技能范围从战斗医生和医护兵到护士、医师助理,偶尔也包括医生。气道阻塞是造成可预防的战场死亡的第二大原因,而是否进行干预以获得气道的决定取决于伤病员的陈述、提供者的舒适度、可用设备以及许多其他变量。在民用院前环境环甲关节切开术(cric)的成功率超过90%,但在美国军事作战环境成功率在0-82%之间。成功率的差异可能是由于培训、环境、设备、患者因素和/或这些因素的综合。许多假定的原因被认为是可变性的根源,但没有研究对第一人称视角进行评估。本研究的重点是采访军事急救人员在现实战斗中放置外科气道,以确定影响他们对成功或失败感知的潜在影响。材料与方法:我们采用深度半结构化访谈的定性研究,了解参与者的真实批评经历。访谈问题是根据关键事件问卷编制的。共有11名参与者,包括4名退役军人和7名现役军人。结果:从11个访谈中产生了9个主题。这些主题可以分为两组:提供者内部的因素,我们称之为内在影响;提供者外部的因素,我们称之为外在影响。内在影响包括个人幸福感、信心、经验和决策。外部影响包括训练、设备、辅助、环境和患者因素。结论:这项研究表明,在战斗环境中,从业者认为有必要在遵循众所周知的气道管理算法的同时,以逐步的方式进行更频繁的训练。更多的重点必须放在利用生物反馈的活组织上,但只有在解剖和地理空间定位在模型、人体模型和尸体上得到很好的理解之后。培训中使用的设备必须是现场可用的设备。最后,培训的重点应放在强调提供者的身体和精神能力的情景上。对自我效能感和刻意练习的真正测试是通过定性数据的内在和外在发现来进行的。所有这些步骤都必须由专业人员监督。另一个关键是提供更多的时间来关注医疗技能的发展,这对整体信心和克服决策过程中的犹豫至关重要。这对于那些接受过最少医学培训、最有可能首先遇到伤员的人,即EMT-Basic级别的提供者来说,更是如此。如果可能的话,在自我效能学习理论下,增加受伤点医疗服务提供者的数量将达到多重目标。帮助会给医生灌输信心,帮助他们快速分清病人的轻重缓急,减少焦虑,减少在战斗环境中表现的犹豫。
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引用次数: 0
Closing the Trauma and Critical Care Gap: A Paradigm Shift through Virtual Reality and Augmented Reality. 缩小创伤和重症监护差距:通过虚拟现实和增强现实的范式转变。
Brian G Gomez, James Winstead, James Lopata, Ryan McMahon

A nationwide surgeon shortage, particularly with general surgeons and trauma surgeons, continues to plague the civilian and military systems readiness. To fill this shortcoming, we provide a narrative review describing current and potential uses of augmented reality and virtual reality (AR/VR) for synthetic training environments which could significantly improve the Army's wartime medical readiness through improved skills of surgeons and non-surgeon providers. Multiple studies demonstrate the potential benefits of AR/VR in cost, time, and critical medical skills for enhanced care delivery. While encouraging, the novelty and relative youth of AR/VR platforms requires further prospective validation as the data for its use as a training adjunct is limited. Nevertheless, state of the art simulated training platforms like AR/VR which mimic surgical trauma cases and review critical surgical skills could help enable a transformation of non-surgeon providers to quickly augment current surgeon personnel shortages.

全国外科医生短缺,特别是普通外科医生和创伤外科医生,继续困扰着民用和军事系统的准备工作。为了弥补这一不足,我们提供了一篇叙述性综述,描述了增强现实和虚拟现实(AR/VR)在综合训练环境中的当前和潜在用途,通过提高外科医生和非外科医生提供者的技能,可以显著改善陆军的战时医疗准备。多项研究表明,AR/VR在成本、时间和关键医疗技能方面具有潜在优势,可以增强医疗服务。虽然令人鼓舞,但AR/VR平台的新颖性和相对年轻,需要进一步的前瞻性验证,因为其作为培训辅助工具的数据有限。然而,最先进的模拟培训平台,如AR/VR,可以模拟外科创伤病例并回顾关键的外科技能,可以帮助实现非外科医生提供者的转变,以迅速弥补目前外科医生人员的短缺。
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引用次数: 0
Neuroprotection and Therapeutic Implications of Creatine Supplementation for Brain Injury Complications. 补充肌酸对脑损伤并发症的神经保护和治疗意义。
Jamison M Newman, Timothy B Pekari, David W Van Wyck

Creatine supplementation has not been researched for Traumatic Brain Injury (TBI) extensively, but studies suggest potential as a neuroprotective agent and potential treatment for brain-injury complications. Patients suffering from TBI experience mitochondrial dysfunction, neuropsychological burden, and deficits in cognitive performance due to malperformance of brain creatine levels, diminished brain Adenosine Triphosphate (ATP) levels, glutamate toxicity, and oxidative stress. In this systemic review, the current available research is reviewed to examine the effects of creatine on common sequalae of TBI within children, adolescents, and mice. Past and present data still lacks the knowledge of creatine supplementation for the adult population and military members during TBI. PubMed was searched for studies which assessed the correlation between creatine supplementation of TBI complications. The search strategy yielded 40 results, of which 15 articles were included in this systemic review. The results of the review supported an apparent understanding creatine does offer an obvious benefit to patients suffering from TBI and post-injury complications under specific guidelines. Time and dose dependent metabolic alterations seem to be only exceptionally prevalent when given as a prophylaxis or if given acutely. Results are only clinically significant after a month of supplementation. Although patients may need many therapeutic treatments to recover from TBI, especially in acute resuscitation, creatine shows superior efficacy as a neuroprotective agent in battling the chronic manifestations which lead to oxidative stress and cognitive function post brain injury.

肌酸补充剂对创伤性脑损伤(TBI)的治疗还没有广泛的研究,但研究表明它可能是一种神经保护剂和脑损伤并发症的潜在治疗方法。脑外伤患者会出现线粒体功能障碍、神经心理负担以及由于脑肌酸水平异常、脑三磷酸腺苷(ATP)水平降低、谷氨酸毒性和氧化应激而导致的认知能力缺陷。在这篇系统综述中,回顾了目前可用的研究,以检查肌酸对儿童、青少年和小鼠创伤性脑损伤常见后遗症的影响。过去和现在的数据仍然缺乏对成年人群和军人在创伤性脑损伤期间补充肌酸的了解。PubMed检索了评估补充肌酸与TBI并发症之间相关性的研究。搜索策略产生40个结果,其中15篇文章被纳入本系统综述。该综述的结果支持了一个明显的理解,即肌酸确实对TBI患者和特定指南下的损伤后并发症有明显的益处。时间和剂量依赖性代谢改变似乎只有在作为预防用药或急性用药时才特别普遍。结果只有在补充一个月后才有临床意义。尽管患者可能需要许多治疗才能从TBI中恢复,特别是在急性复苏中,肌酸作为一种神经保护剂在对抗脑损伤后导致氧化应激和认知功能的慢性表现方面表现出优越的疗效。
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引用次数: 0
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Medical journal (Fort Sam Houston, Tex.)
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