{"title":"Necrotizing enterocolitis in a Chinese perspective: a narrative review","authors":"Xiao-Chen Liu, Lu-Quan Li","doi":"10.21037/pm-22-39","DOIUrl":"https://doi.org/10.21037/pm-22-39","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67563898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Caballero-Alvarado, Karla Rodríguez Millones, Mylenia Ruiz Gonzales, Annel B. Rojas Alvarado, Carlos Zavaleta Corvera, J. J. Barboza
{"title":"Ischemic stroke associated with Multisystemic Inflammatory Syndrome in children after SARS-CoV-2 infection: a case report","authors":"J. Caballero-Alvarado, Karla Rodríguez Millones, Mylenia Ruiz Gonzales, Annel B. Rojas Alvarado, Carlos Zavaleta Corvera, J. J. Barboza","doi":"10.21037/pm-22-43","DOIUrl":"https://doi.org/10.21037/pm-22-43","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46468478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Padilla-Sánchez, Susana Baixauli-Alacreu, Á. Solaz-García, Inmaculada Lara-Cantón, A. Parra-Llorca, M. Vento
{"title":"Reference ranges for SpO2, respiratory rate, and tidal volume in term newborn infants after birth: a narrative review","authors":"C. Padilla-Sánchez, Susana Baixauli-Alacreu, Á. Solaz-García, Inmaculada Lara-Cantón, A. Parra-Llorca, M. Vento","doi":"10.21037/pm-21-75","DOIUrl":"https://doi.org/10.21037/pm-21-75","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45962856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Halabi, Taylor Beedie, J. Walsh, Michael R. Miller, A. Zizzo
{"title":"Correlation of elevated transaminases and histological findings in children with celiac disease: a retrospective cross-sectional study","authors":"M. Halabi, Taylor Beedie, J. Walsh, Michael R. Miller, A. Zizzo","doi":"10.21037/pm-22-58","DOIUrl":"https://doi.org/10.21037/pm-22-58","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43169479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management strategies in pediatric allergic rhinitis—are we missing?","authors":"Taral K. Parikh","doi":"10.21037/pm-22-30","DOIUrl":"https://doi.org/10.21037/pm-22-30","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45783009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Bansal, S. Momin, R. Bansal, Sujith Kumar Reddy Gurram Venkata, L. Ruser, K. Yusuf
{"title":"Pharmacokinetics of drugs: newborn perspective","authors":"N. Bansal, S. Momin, R. Bansal, Sujith Kumar Reddy Gurram Venkata, L. Ruser, K. Yusuf","doi":"10.21037/pm-22-11","DOIUrl":"https://doi.org/10.21037/pm-22-11","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43695322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A narrative review of type 2 diabetes mellitus and its management in children and adolescents","authors":"Patricia J. Vining Maravolo, E. Clemente","doi":"10.21037/pm-21-103","DOIUrl":"https://doi.org/10.21037/pm-21-103","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":"557 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41263080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A narrative review of gender dysphoria in childhood and adolescence: definition, epidemiology, and clinical recognition","authors":"E. Clemente, Judy Jasser, Katelyn Jean Koenig","doi":"10.21037/pm-21-95","DOIUrl":"https://doi.org/10.21037/pm-21-95","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42413892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The leaky gut: a narrative review on the role of epithelial cell permeability in necrotizing enterocolitis","authors":"K. B. Snyder, C. Hunter","doi":"10.21037/pm-22-41","DOIUrl":"https://doi.org/10.21037/pm-22-41","url":null,"abstract":"","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46895613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Talia Baird, A. Kirpalani, M. Knauer, Brett Plouffe, Farah Abdulsatar
Introduction: Serious pediatric systemic adverse events following receipt of the messenger ribonucleic acid (mRNA) vaccines such as Pfizer/BioNTech vaccine (BNT162b2-V) are rare, with the most common being myocarditis. We report a case of severe rhabdomyolysis following receipt of BNT162b2-V and review the literature for reports in children. To our knowledge, this is the first case of severe rhabdomyolysis temporally associated with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccine in a healthy adolescent without a predisposing cause. Case Description: A previously healthy16-year-old female developed extensive and severe myalgias and generalized weakness following dose two of BNT162b2-V. She had severe rhabdomyolysis with a peak creatinine kinase (CK) of 246,900 U/L at 92 hours post-vaccination. SARS-CoV-2 polymerase chain reaction (PCR) testing and antibody to nucleocapsid were negative. Extensive workup revealed no alternative causes. The patient was treated effectively with intravenous hyperhydration over a 3-day hospital admission. As of July 9th, 2021, four pediatric cases of rhabdomyolysis temporally associated with SARS-CoV-2 vaccination were identified in the Vaccine Adverse Event Reporting System (VAERS) database. Case 1 was a 17-yearold male with drug overdose (loratadine and doxylamine) 5 days post dose two of BNT162b2-V. He was found to have rhabdomyolysis and myocarditis. Case 2 was a 12-year-old female with bilateral arm weakness post dose two of BNT162b2-V and a peak CK of 7000 U/L. Rigorous exercise was implicated as a cause in this case. Case 3 was a 14-year-old female who accidently received a triple BNT162b2-V dose (undiluted dose) and developed chest pain, her CK was 7000 U/L. Case 4 was a 14-year-old male who developed myalgias post dose one of BNT162b2-V and had mild rhabdomyolysis with a CK of 1600 U/L. Discussion: Rhabdomyolysis has been reported following vaccines including BNT162b2-V but without a causal link. Although our case is the fifth adolescent reported, our case is unique given the absence of an identifiable trigger and the severity of rhabdomyolysis. The development of symptoms in close proximity to vaccine administration and in the absence of another identifiable trigger raises concerns about a potential link. Although exaggerated immune response in vaccine recipients who have had previous SARS-CoV-2 infection has been postulated, the absence of nucleocapsid antibodies does not support this in our patient. Immune mediated or aberrant autoimmune responses to adjuvants in the SARS-CoV-2 vaccine, as seen in the autoimmune inflammatory syndrome induced by adjuvants (ASIA) is another possibility. Post-vaccination autoimmune phenomena have been documented in connection to various vaccines. Conclusion: As more healthy adolescents with robust immune systems become vaccinated, it is important for clinicians to identify rhabdomyolysis post- SARS-CoV-2 vaccination to allow for timely intervention and pr
{"title":"Severe rhabdomyolysis temporally associated with SARS-CoV-2 vaccine in an adolescent: a case report","authors":"Talia Baird, A. Kirpalani, M. Knauer, Brett Plouffe, Farah Abdulsatar","doi":"10.21037/pm-22-18","DOIUrl":"https://doi.org/10.21037/pm-22-18","url":null,"abstract":"Introduction: Serious pediatric systemic adverse events following receipt of the messenger ribonucleic acid (mRNA) vaccines such as Pfizer/BioNTech vaccine (BNT162b2-V) are rare, with the most common being myocarditis. We report a case of severe rhabdomyolysis following receipt of BNT162b2-V and review the literature for reports in children. To our knowledge, this is the first case of severe rhabdomyolysis temporally associated with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccine in a healthy adolescent without a predisposing cause. Case Description: A previously healthy16-year-old female developed extensive and severe myalgias and generalized weakness following dose two of BNT162b2-V. She had severe rhabdomyolysis with a peak creatinine kinase (CK) of 246,900 U/L at 92 hours post-vaccination. SARS-CoV-2 polymerase chain reaction (PCR) testing and antibody to nucleocapsid were negative. Extensive workup revealed no alternative causes. The patient was treated effectively with intravenous hyperhydration over a 3-day hospital admission. As of July 9th, 2021, four pediatric cases of rhabdomyolysis temporally associated with SARS-CoV-2 vaccination were identified in the Vaccine Adverse Event Reporting System (VAERS) database. Case 1 was a 17-yearold male with drug overdose (loratadine and doxylamine) 5 days post dose two of BNT162b2-V. He was found to have rhabdomyolysis and myocarditis. Case 2 was a 12-year-old female with bilateral arm weakness post dose two of BNT162b2-V and a peak CK of 7000 U/L. Rigorous exercise was implicated as a cause in this case. Case 3 was a 14-year-old female who accidently received a triple BNT162b2-V dose (undiluted dose) and developed chest pain, her CK was 7000 U/L. Case 4 was a 14-year-old male who developed myalgias post dose one of BNT162b2-V and had mild rhabdomyolysis with a CK of 1600 U/L. Discussion: Rhabdomyolysis has been reported following vaccines including BNT162b2-V but without a causal link. Although our case is the fifth adolescent reported, our case is unique given the absence of an identifiable trigger and the severity of rhabdomyolysis. The development of symptoms in close proximity to vaccine administration and in the absence of another identifiable trigger raises concerns about a potential link. Although exaggerated immune response in vaccine recipients who have had previous SARS-CoV-2 infection has been postulated, the absence of nucleocapsid antibodies does not support this in our patient. Immune mediated or aberrant autoimmune responses to adjuvants in the SARS-CoV-2 vaccine, as seen in the autoimmune inflammatory syndrome induced by adjuvants (ASIA) is another possibility. Post-vaccination autoimmune phenomena have been documented in connection to various vaccines. Conclusion: As more healthy adolescents with robust immune systems become vaccinated, it is important for clinicians to identify rhabdomyolysis post- SARS-CoV-2 vaccination to allow for timely intervention and pr","PeriodicalId":74411,"journal":{"name":"Pediatric medicine (Hong Kong, China)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44046937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：