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Development and Comparative Efficacy of Lagos Neuropathy Protocol for Improving Recovery of Symptom and Functional Independence Performance in Individuals with Diabetic Peripheral Sensorimotor Polyneuropathy. 拉各斯神经病方案在改善糖尿病周围感觉运动多发性神经病患者症状和功能独立表现恢复中的发展和比较疗效。
Pub Date : 2021-02-24 eCollection Date: 2021-01-01 DOI: 10.1298/ptr.E10070
Caleb Ademola Omuwa Gbiri, Hammed Olaoye Iyiola, Jibrin Sammani Usman, Caleb Adewumi Adeagbo, Babatunde Lekan Ileyemi, Ngozi Florence Onuegbu, Francis-Beloved Odinakachukwu Odidika

Background: Diabetic peripheral sensorimotor polyneuropathy (DPSP) has been treated with sketchy outcomes and available approaches are not applicable for self-administration. This study developed protocol for managing symptoms of DPSP and assessed its comparative efficacy.

Methods: Study developed Lagos Neuropathy Protocol (LNP) through existing concept in DPSP and tested its safety, clinical applicability, and ease of self-administration. Its efficacy was compared with Buerger-Allen Exercise (BAE) by involving 31(11males) with DPSP, randomized into LNP and BAE and treated for 10-week. Toronto Clinical Scoring System was used to diagnose DPSP while Diabetic Neuropathy Examination was used to diagnose distal polyneuropathy. Sensory/pressure perception was assessed using 10 g-monofilament while Short Physical Performance Battery, Bergs Balance Scale and Visual Analogue Scale was used to assess functional performance, strength and balance, and pain respectively.

Results: LNP has three domains: sensory/pressure/proprioception, strength/balance, and pain/swelling. Most (80%) of the participants rated the LNP as excellently safe while the rest (20%) rated as very good in safety. All the participants rated LNP excellent in terms of self-administration and suitability for clinical use without adverse effect. The mean age of the participants for the comparative phase was 66.20±9.48years while their length of diagnoses of diabetes was 15.80±13.35years. About a third (32.5%) had DPSP. Both LNP and BAE had significant improvement (p<0.05) in sensory/pressure perception, pain, strength and balance, and functional performance but LNP had better significant improvement.

Conclusion: LNP is safe, good for self-administration, clinically applicable and efficacious in improving sensory/pressure perception, balance, pain and functional performances in individuals with DPSP.

背景:糖尿病外周感觉运动性多发性神经病(DPSP)的治疗结果很粗略,现有的方法不适用于自行给药。本研究制定了DPSP症状管理方案,并评估了其比较疗效。方法:本研究通过DPSP中现有的概念开发了拉各斯神经病变方案(LNP),并测试了其安全性、临床适用性和自我给药的简易性。通过将31名(11名男性)DPSP患者随机分为LNP和BAE,并治疗10周,将其疗效与Buerger-Allen Exercise(BAE)进行比较。多伦多临床评分系统用于诊断DPSP,糖尿病神经病变检查用于诊断远端多发性神经病。使用10g单丝评估感觉/压力感知,同时使用短期物理性能量表、Bergs平衡量表和视觉模拟量表分别评估功能性能、力量和平衡以及疼痛。结果:LNP有三个领域:感觉/压力/本体感觉、力量/平衡和疼痛/肿胀。大多数(80%)的参与者认为LNP非常安全,而其余(20%)的参与者则认为其安全性非常好。所有参与者都认为LNP在自我给药和临床应用适用性方面表现出色,没有不良反应。比较阶段参与者的平均年龄为66.20±9.48岁,而他们诊断糖尿病的时间为15.80±13.35岁。大约三分之一(32.5%)患有DPSP。LNP和BAE均有显著改善(pLNP有更好的显著改善)。结论:LNP安全、易于自我给药、临床适用,对改善DPSP患者的感觉/压力感知、平衡、疼痛和功能表现有效。
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引用次数: 0
Psoas Muscle Volume and Attenuation are Better Predictors than Muscle Area for Hospital Readmission in Older Patients after Transcatheter Aortic Valve Implantation. 腰肌体积和衰减比肌肉面积更能预测经导管主动脉瓣植入术后老年患者的再住院情况。
Pub Date : 2021-02-24 eCollection Date: 2021-01-01 DOI: 10.1298/ptr.E10079
Akihiro Sakuyama, Masakazu Saitoh, Keigo Iwai, Kazuki Kon, Kentaro Hori, Masatoshi Nagayama

Objective: This study aimed to determine whether the psoas muscle volume (PMV) and its muscle attenuation (MA) are associated with hospital readmission after transcatheter aortic valve implantation (TAVI).

Method: We included 113 older patients with aortic stenosis who underwent TAVI at Sakakibara Heart Institute (mean age 85 ± 5 years, 69% women). We measured PMV and psoas muscle area (PMA) as well as total muscle area (TMA) at the third lumbar vertebra using preoperative computed tomography (CT) images. The crude values of the PMV, PMA, and TMA were normalized by dividing by height squared.

Results: The median follow-up period was 724 days (interquartile range: 528-730 days), and there were 25 all-cause readmissions during the follow-up period (22% of all patients). In the multivariate Cox regression analysis adjusted for age, sex, and EuroSCORE II, the PMV and its MA and crude PMA were significantly associated with all-cause readmission [HR: 0.957 (0.930-0.985), p = 0.003, HR: 0.927 (0.862-0.997), p = 0.040], whereas the PMA and TMA and each MA were not (all p > 0.05). The groups with low PMV and MA had significantly higher incidences of all-cause readmission than that with high PMV and MA (log-rank test: p = 0.011).

Conclusion: PMV and its MA measured from preoperative CT images were independent predictors of all-cause readmission in TAVI patients.

目的本研究旨在确定腰肌体积(PMV)及其肌肉衰减(MA)是否与经导管主动脉瓣植入术(TAVI)后再入院相关:我们纳入了113名在榊原心脏研究所接受TAVI手术的主动脉瓣狭窄老年患者(平均年龄85 ± 5岁,69%为女性)。我们使用术前计算机断层扫描(CT)图像测量了第三腰椎处的PMV、腰肌面积(PMA)和总肌肉面积(TMA)。PMV、PMA和TMA的粗略值通过除以身高平方进行归一化处理:中位随访期为 724 天(四分位间范围:528-730 天),随访期间共有 25 例全因再入院(占所有患者的 22%)。在调整了年龄、性别和 EuroSCORE II 后的多变量 Cox 回归分析中,PMV 及其 MA 和粗 PMA 与全因再入院显著相关[HR:0.957 (0.930-0.985),p = 0.003,HR:0.927 (0.862-0.997),p = 0.040],而 PMA 和 TMA 以及每个 MA 则不相关(所有 p > 0.05)。低 PMV 和 MA 组的全因再入院发生率明显高于高 PMV 和 MA 组(对数秩检验:P = 0.011):结论:通过术前 CT 图像测量的 PMV 及其 MA 是 TAVI 患者全因再入院的独立预测因素。
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引用次数: 0
Effects of Physical Agents on Muscle Healing with a Focus on Animal Model Research. 物理制剂对肌肉愈合的影响——以动物模型研究为重点。
Pub Date : 2021-02-24 eCollection Date: 2021-01-01 DOI: 10.1298/ptr.R0011
Miki Sakamoto

Skeletal muscle injury is caused by a variety of events, such as muscle laceration, contusions, or strain. Muscle fibers respond to minor damage with immediate repair mechanisms that reseal the cell membrane. On the other hand, repair of irreversibly damaged fibers is achieved by activation of muscle precursor cells. Muscle repair is not always perfect, especially after severe damage, and can lead to excessive fibroblast proliferation that results in the formation of scar tissue within muscle fibers. Remaining scar tissue can impair joint movement, reduce muscular strength, and inhibit exercise ability; therefore, to restore muscle function, minimizing the extent of injury and promoting muscle regeneration are necessary. Various physical agents, such as cold, thermal, electrical stimulation, and low-intensity pulsed ultrasound therapy, have been reported as treatments for muscle healing. Although approaches based on the muscle regeneration process have been under development, the most efficacious physiological treatment for muscle injury remains unclear. In this review, the influence of these physical agents on muscle injury is described with a focus on research using animal models.

骨骼肌损伤是由多种事件引起的,如肌肉撕裂、挫伤或拉伤。肌肉纤维对轻微损伤作出反应,立即修复机制,重新封闭细胞膜。另一方面,不可逆损伤纤维的修复是通过激活肌肉前体细胞来实现的。肌肉修复并不总是完美的,特别是在严重损伤之后,并且可能导致成纤维细胞过度增殖,导致肌肉纤维内瘢痕组织的形成。残留的疤痕组织会损害关节活动,降低肌肉力量,抑制运动能力;因此,要恢复肌肉功能,必须尽量减少损伤程度,促进肌肉再生。各种物理试剂,如冷、热、电刺激和低强度脉冲超声治疗,已被报道为肌肉愈合的治疗方法。尽管基于肌肉再生过程的方法一直在发展中,但对肌肉损伤最有效的生理治疗仍不清楚。在这篇综述中,这些物理剂对肌肉损伤的影响被描述,重点是用动物模型研究。
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引用次数: 2
Effect of a Combined Exercise and Cognitive Activity Intervention on Cognitive Function in Community-dwelling Older Adults: A Pilot Randomized Controlled Trial. 运动和认知活动联合干预对社区老年人认知功能的影响:一项随机对照试验。
Pub Date : 2021-02-24 eCollection Date: 2021-01-01 DOI: 10.1298/ptr.E10057
Shunsuke Murata, Rei Ono, Hisafumi Yasuda, Rumi Tanemura, Yoshiaki Kido, Hisatomo Kowa

Objective: The purpose of this study is to investigate the effect of an intervention combining exercise and cognitive activity on cognitive function in healthy older adults.

Methods: This pilot randomized controlled trial recruited 33 eligible, healthy communitydwelling older adults (mean age, 77.1 years old; women, 51.5%), who were divided into intervention and waitlist control groups. The intervention group was engaged weekly in a group activity comprising exercise and discussions of homework, which included reading aloud, simple arithmetic, and simple activities, like spotting differences, for cognitive stimulation. They were also required to complete cognitive activity homework twice a week. The waitlist control group received no intervention. The main outcomes were cognitive function assessed using the Mini-Mental State Examination, delayed recall score on the Logical Memory IIA of the Wechsler Memory Scale Revised, Trail Making Test, and digit symbol substitution test.

Results: According to the results, Mini-Mental State Examination scores were maintained in the intervention group but declined in the control group [Mean change in outcomes in control group (95% confidence interval): -1.68 (-2.89 to -0.48)]. Additional mean change in outcomes in intervention group were found [1.68 (0.02 to 3.35)].

Conclusions: Interventions combining exercise and cognitive activity can be helpful for preserving cognitive function in healthy older adults.

目的:本研究的目的是探讨运动与认知活动相结合的干预对健康老年人认知功能的影响。方法:本试点随机对照试验招募33名符合条件的健康社区老年人(平均年龄77.1岁;女性(51.5%),她们被分为干预组和候补组。干预组每周参加一个小组活动,包括练习和讨论家庭作业,其中包括大声朗读,简单的算术,以及简单的活动,如发现差异,以促进认知。他们还被要求每周完成两次认知活动作业。等候名单控制组没有接受任何干预。主要结果为认知功能评估,采用迷你精神状态测试,韦氏记忆量表修订后的逻辑记忆IIA延迟回忆评分,轨迹测试和数字符号替代测试。结果:结果显示,干预组基本维持精神状态检查得分,对照组得分下降[对照组结果平均变化(95%可信区间):-1.68(-2.89 ~ -0.48)]。干预组结果平均变化[1.68(0.02 ~ 3.35)]。结论:运动与认知活动相结合的干预措施有助于保持健康老年人的认知功能。
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引用次数: 3
Editorial Board 编辑委员会
Pub Date : 2020-12-20 DOI: 10.1298/ptr.editor2302
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引用次数: 0
Physical Therapy Japan Vol.46 (2019) ABSTRACTS 物理治疗日本Vol.46(2019)摘要
Pub Date : 2020-12-20 DOI: 10.1298/ptr.abstract2302
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引用次数: 0
Age-Related Change in Muscle Characteristics and Resistance Training for Older Adults. 老年人肌肉特征和阻力训练的年龄相关变化。
Pub Date : 2020-12-04 eCollection Date: 2020-01-01 DOI: 10.1298/ptr.R0009
Tome Ikezoe

In older adults, muscle weakness contributes greatly to functional restrictions on daily living activities, increased risk of falls, and adverse physiological changes. It has been suggested that not only muscle mass but also muscular infiltration of noncontractile elements may influence muscular performance such as strength and rapid force production. It is proved that resistance training may provoke substantial increases in muscle size even if it is performed at low intensities in older individuals. Also, recent studies have demonstrated the effectiveness of resistance training on muscle quality such as muscular infiltration of noncontractile elements for older people. This review shows the age-related changes in muscle mass and muscle quality, which were measured by muscle echo intensity on ultrasound images, and low-intensity resistance training effects on muscle volume and muscle quality.

在老年人中,肌肉无力在很大程度上限制了日常生活活动的功能,增加了跌倒的风险和不利的生理变化。有人认为,不仅肌肉质量,而且非收缩元素的肌肉浸润也可能影响肌肉性能,如力量和快速发力。事实证明,即使在老年人中进行低强度的阻力训练,也可能引起肌肉大小的大幅增加。此外,最近的研究已经证明了阻力训练对肌肉质量的有效性,例如老年人的非收缩元素的肌肉渗透。这篇综述显示了肌肉量和肌肉质量的年龄相关变化,这是通过超声图像上的肌肉回声强度来测量的,以及低强度阻力训练对肌肉量和肌肉质量的影响。
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引用次数: 6
Change in motor cortex activation for muscle release by motor learning. 运动学习对肌肉释放的运动皮层激活变化。
Pub Date : 2020-12-04 eCollection Date: 2020-01-01 DOI: 10.1298/ptr.R0010
Kenichi Sugawara

For central nervous system disorders' rehabilitation, it is important to accurately understand motor control and implement an appropriate motor learning process to induce neuroplastic changes. The neurophysiological studies have revealed that neural control mechanisms are crucial during both the onset of muscular activities and muscle release after contraction. When performing various movements during daily activities, muscle relaxation control enables precise force output and timing control. Moreover, surround inhibition is a functional mechanism in the motor system. Surround inhibition of the motor system may be involved in the selective execution of desired movements. This review demonstrates cortical excitability resulting from motor learning, movement control mechanisms including muscle relaxation and the suppression of nontarget muscle groups, and the voluntary drive's importance that is required for movement.

对于中枢神经系统疾病的康复来说,准确理解运动控制并实施适当的运动学习过程以诱导神经可塑性改变是非常重要的。神经生理学研究表明,神经控制机制在肌肉活动的开始和肌肉收缩后的释放过程中都起着至关重要的作用。在日常活动中进行各种动作时,肌肉放松控制可以精确输出力和定时控制。此外,环绕抑制是运动系统中的一种功能机制。运动系统的环绕抑制可能与选择性地执行期望的运动有关。这篇综述展示了由运动学习、运动控制机制(包括肌肉松弛和非目标肌群的抑制)以及运动所需的随意驱动的重要性引起的皮质兴奋性。
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引用次数: 2
Minimum standards of clinical practice for physical therapists working in intensive care units in Japan. 日本重症监护病房物理治疗师临床实践的最低标准。
Pub Date : 2020-11-25 eCollection Date: 2021-01-01 DOI: 10.1298/ptr.E10060
Tetsuya Takahashi, Michitaka Kato, Kengo Obata, Ryo Kozu, Toru Fujimoto, Koji Yamashita, Morihide Ando, Yusuke Kawai, Noriaki Kojima, Hiroshi Komatsu, Kensuke Nakamura, Yuhei Yamashita, Shane Patman, Akemi Utsunomiya, Osamu Nishida

Objective: Early mobilization and rehabilitation has become common and expectations for physical therapists working in intensive care units have increased in Japan. The objective of this study was to establish consensus-based minimum clinical practice standards for physical therapists working in intensive care units in Japan. It also aimed to make an international comparison of minimum clinical practice standards in this area.

Methods: In total, 54 experienced physical therapists gave informed consent and participated in this study. A modified Delphi method with questionnaires was used over three rounds. Participants rated 272 items as "essential/unknown/non-essential". Consensus was considered to be reached on items that over 70% of physical therapists rated as "essential" to clinical practice in the intensive care unit.

Results: Of the 272 items in the first round, 188 were deemed essential. In round 2, 11 of the 62 items that failed to reach consensus in round 1 were additionally deemed essential. No item was added to the "essential" consensus in round 3. In total, 199 items were therefore deemed essential as a minimum standard of clinical practice. Participants agreed that 42 items were not essential and failed to reach agreement on 31 others. Identified 199 items were different from those in the UK and Australia due to national laws, cultural and historical backgrounds.

Conclusions: This is the first study to develop a consensus-based minimum clinical practice standard for physical therapists working in intensive care units in Japan.

目的:在日本,早期动员和康复已经变得普遍,对在重症监护病房工作的物理治疗师的期望也有所增加。本研究的目的是为在日本重症监护病房工作的物理治疗师建立基于共识的最低临床实践标准。它还旨在对这一领域的最低临床实践标准进行国际比较。方法:共有54名经验丰富的物理治疗师知情同意并参与本研究。采用改进的德尔菲法和问卷调查法进行了三轮调查。参与者将272项物品分为“必要/未知/非必要”。超过70%的物理治疗师认为在重症监护病房的临床实践中“必不可少”的项目被认为达成了共识。结果:在第一轮的272项中,有188项被认为是必不可少的。在第二轮中,在第一轮未能达成共识的62个项目中,有11个项目被认为是必要的。第3轮的“基本”协商一致意见没有增加任何项目。因此,总共有199个项目被认为是临床实践的最低标准。与会者一致认为,有42个项目并非必不可少,另有31个项目未能达成一致。由于国家法律、文化和历史背景的不同,鉴定出的199个项目与英国和澳大利亚的不同。结论:这是第一个为日本重症监护室物理治疗师制定基于共识的最低临床实践标准的研究。
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引用次数: 7
Relationships between Gross Motor Abilities and Sensory Processing in Children Aged 18 to 36 Months. 18 ~ 36月龄儿童粗大运动能力与感觉加工的关系。
Pub Date : 2020-11-25 eCollection Date: 2021-01-01 DOI: 10.1298/ptr.E10051
Eri Takahashi, Osamu Nitta, Kenji Takaki, Yuichi Toba

Objective: We investigated the relationship between gross motor abilities and sensory processing in typically developing children.

Method: Participants included children aged 18 to 36 months (N = 48). All participants were full-term infants. We assessed gross motor abilities based on the Gross Motor Function Measure (GMFM), and sensory processing characteristics based on the Infant/Toddler Sensory Profile (ITSP). The gross motor ability index was calculated using GMFM score which was estimated from the age. Pearson's product moment correlation coefficients were used to examine the relationships between the gross motor ability indexes and ITSP section scores.

Results: Our findings showed that gross motor ability may be related to oral sensory processing. The children who were more responsive to oral sensory processing tended to exhibit gross motor abilities below the standard for that age.

Conclusion: Gross motor abilities were related with sensory processing, especially oral sensory processing, in children aged 18 to 36 months.

目的:探讨正常发育儿童大肌肉运动能力与感觉加工的关系。方法:参与者为18 ~ 36月龄儿童(N = 48)。所有的参与者都是足月婴儿。我们根据大运动功能量表(GMFM)评估大运动能力,根据婴幼儿感觉档案(ITSP)评估感觉加工特征。大运动能力指数采用GMFM评分计算,GMFM评分从年龄开始计算。采用Pearson积矩相关系数检验大肌肉运动能力指标与ITSP评分之间的关系。结果:大肌肉运动能力可能与口腔感觉加工有关。对口腔感觉处理反应更灵敏的儿童,其大肌肉运动能力往往低于该年龄的标准。结论:18 ~ 36月龄儿童粗大运动能力与感觉加工,尤其是口腔感觉加工有关。
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引用次数: 0
期刊
Physical therapy research
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