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Proceedings of the IEEE ... annual Northeast Bioengineering Conference. IEEE Northeast Bioengineering Conference最新文献

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Design of a Wireless EEG System for Point-of-Care Applications. 面向即时护理应用的无线脑电图系统设计。
Wenyan Jia, Yicheng Bai, Mingui Sun, Robert J Sclabassi

This study aims to develop a wireless EEG system to provide critical point-of-care information about brain electrical activity. A novel dry electrode, which can be installed rapidly, is used to acquire EEG from the scalp. A wireless data link between the electrode and a data port (i.e., a smartphone) is established based on the Bluetooth technology. A prototype of this system has been implemented and its performance in acquiring EEG has been evaluated.

本研究旨在开发一种无线脑电图系统,以提供关键的脑电活动信息。一种可快速安装的新型干电极用于采集头皮的脑电图。在电极和数据端口(即智能手机)之间建立基于蓝牙技术的无线数据链路。实现了该系统的原型,并对其在脑电信号采集中的性能进行了评价。
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引用次数: 1
Eating Event Detection by Magnetic Proximity Sensing. 磁性近距离感应进食事件检测。
Chengliu Li, Yicheng Bai, Wenyan Jia, Mingui Sun

Eating event detection is an important problem in automatic dietary study using a wearable computer, such as the eButton. In this work, we approach this detection problem based on the use of a small magnet marker attached to a finger and a miniature magnetometer installed within the eButton. Our experimental results indicate that our magnetic approach is effective when the distance between the marker and the wearable computer is within 12cm, and the range of detection is approximately 15cm. We also found that the proximity signal patterns corresponding to eating and other daily activities are different, which can be used to reduce the false detection rate. In addition, our approach is convenient, low-cost and energy efficient, suitable for practical applications.

在使用eButton等可穿戴计算机进行自动饮食研究中,饮食事件检测是一个重要问题。在这项工作中,我们通过使用附着在手指上的小磁铁标记和安装在eButton内的微型磁力计来解决这个检测问题。实验结果表明,当标记与可穿戴计算机之间的距离在12cm以内,检测范围约为15cm时,磁性方法是有效的。我们还发现,与进食和其他日常活动相对应的接近信号模式是不同的,这可以用来降低误检率。此外,我们的方法方便、低成本、节能,适合实际应用。
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引用次数: 6
3D/2D Model-to-Image Registration for Quantitative Dietary Assessment. 定量膳食评估的3D/2D模型到图像配准。
Hsin-Chen Chen, Wenyan Jia, Zhaoxin Li, Yung-Nien Sun, Mingui Sun

Image-based dietary assessment is important for health monitoring and management because it can provide quantitative and objective information, such as food volume, nutrition type, and calorie intake. In this paper, a new framework, 3D/2D model-to-image registration, is presented for estimating food volume from a single-view 2D image containing a reference object (i.e., a circular dining plate). First, the food is segmented from the background image based on Otsu's thresholding and morphological operations. Next, the food volume is obtained from a user-selected, 3D shape model. The position, orientation and scale of the model are optimized by a model-to-image registration process. Then, the circular plate in the image is fitted and its spatial information is used as constraints for solving the registration problem. Our method takes the global contour information of the shape model into account to obtain a reliable food volume estimate. Experimental results using regularly shaped test objects and realistically shaped food models with known volumes both demonstrate the effectiveness of our method.

基于图像的饮食评估对于健康监测和管理非常重要,因为它可以提供定量和客观的信息,如食物量、营养类型和卡路里摄入量。本文提出了一种新的框架,3D/2D模型-图像配准,用于从包含参考对象(即圆形餐盘)的单视图2D图像中估计食物体积。首先,基于Otsu的阈值分割和形态学操作,从背景图像中分割出食物;接下来,从用户选择的3D形状模型中获得食物体积。通过模型到图像的配准过程对模型的位置、方向和比例进行优化。然后,对图像中的圆板进行拟合,并将其空间信息作为约束条件求解配准问题;我们的方法考虑了形状模型的全局轮廓信息,以获得可靠的食物体积估计。使用规则形状的测试对象和具有已知体积的真实形状的食物模型的实验结果都证明了我们的方法的有效性。
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引用次数: 27
Designing a Wearable Computer for Lifestyle Evaluation. 设计一种用于生活方式评估的可穿戴计算机。
Yicheng Bai, Chengliu Li, Yaofeng Yue, Wenyan Jia, Jie Li, Zhi-Hong Mao, Mingui Sun

A wearable computer, called eButton, has been developed for evaluation of the human lifestyle. This ARM-based device acquires multimodal data from a camera module, a motion sensor, an orientation sensor, a light sensor and a GPS receiver. Its performance has been tested both in our laboratory and by human subjects in free-living conditions. Our results indicate that eButton can record real-world data reliably, providing a powerful tool for the evaluation of lifestyle for a broad range of applications.

一种名为eButton的可穿戴电脑被开发出来,用于评估人类的生活方式。这个基于arm的设备从一个摄像头模块、一个运动传感器、一个方向传感器、一个光传感器和一个GPS接收器获取多模态数据。它的性能已经在我们的实验室和人类受试者在自由生活的条件下进行了测试。我们的研究结果表明,eButton可以可靠地记录真实世界的数据,为广泛应用的生活方式评估提供了一个强大的工具。
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引用次数: 40
Portable Amplifier Design for a Novel EEG Monitor in Point-of-Care Applications. 新型脑电图监护仪的便携式放大器设计。
Bo Luan, Mingui Sun, Wenyan Jia

The Electroencephalography (EEG) is a common diagnostic tool for neurological diseases and dysfunctions, such as epilepsy and insomnia. However, the current EEG technology cannot be utilized quickly and conveniently at the point of care due to the complex skin preparation procedures required and the inconvenient EEG data acquisition systems. This work presents a portable amplifier design that integrates a set of skin screw electrodes and a wireless data link. The battery-operated amplifier contains an instrumentation amplifier, two noninverting amplifiers, two high-pass filters, and a low-pass filter. It is able to magnify the EEG signals over 10,000 times and has a high impedance, low noise, small size and low weight. Our electrode and amplifier are ideal for point-of-care applications, especially during transportation of patients suffering from traumatic brain injury or stroke.

脑电图(EEG)是神经系统疾病和功能障碍的常用诊断工具,如癫痫和失眠。然而,由于需要复杂的皮肤准备程序和不方便的脑电图数据采集系统,目前的脑电图技术无法在护理点快速方便地使用。这项工作提出了一种便携式放大器设计,集成了一套皮肤螺旋电极和无线数据链路。电池供电放大器包含一个仪表放大器,两个非反相放大器,两个高通滤波器和一个低通滤波器。它能将脑电图信号放大10000倍以上,具有高阻抗、低噪声、体积小、重量轻等特点。我们的电极和放大器是理想的点护理应用,特别是在运输患者遭受创伤性脑损伤或中风。
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引用次数: 9
Effects of lipids on dissolution of poorly water-soluble drugs 脂类对难水溶性药物溶解的影响
S. Maio
Despite the significance of fat-rich food/drug interactions, there is an incomplete understanding of the influence of ingested lipids on orally delivered hydrophobic drug bioavailability. In order to determine the impact of lipid and lipid digestion on drug dissolution and absorption, an updated in vitro lipid digestion model has been designed based on knowledge of gastrointestinal contents. The digestion kinetics sensitivity to key parameters, including pH, calcium concentration, and lipid substrate, has been studied. In vitro lipolysis experiments have been coupled with several techniques, such as dynamic light scattering (DLS), and electron paramagnetic resonance (EPR), to characterize respectively: size and morphology of colloidal particles, and dynamic drug partitioning between phases.
尽管富含脂肪的食物/药物相互作用具有重要意义,但人们对摄入的脂类对口服疏水药物生物利用度的影响的了解并不完全。为了确定脂质和脂质消化对药物溶解和吸收的影响,基于胃肠道内容物的知识,设计了一个更新的体外脂质消化模型。消化动力学对关键参数,包括pH,钙浓度和脂质底物的敏感性进行了研究。体外脂解实验结合了多种技术,如动态光散射(DLS)和电子顺磁共振(EPR),分别表征了胶体颗粒的大小和形态,以及相间药物的动态分配。
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引用次数: 1
期刊
Proceedings of the IEEE ... annual Northeast Bioengineering Conference. IEEE Northeast Bioengineering Conference
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