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Shape-based Similarity Retrieval of Doppler Images for Clinical Decision Support. 基于形状的多普勒图像相似性检索用于临床决策支持
Pub Date : 2010-06-01 Epub Date: 2010-08-05 DOI: 10.1109/CVPR.2010.5540126
T Syeda-Mahmood, P Turaga, D Beymer, F Wang, A Amir, H Greenspan, K Pohl

Flow Doppler imaging has become an integral part of an echocardiographic exam. Automated interpretation of flow doppler imaging has so far been restricted to obtaining hemodynamic information from velocity-time profiles depicted in these images. In this paper we exploit the shape patterns in Doppler images to infer the similarity in valvular disease labels for purposes of automated clinical decision support. Specifically, we model the similarity in appearance of Doppler images from the same disease class as a constrained non-rigid translation transform of the velocity envelopes embedded in these images. The shape similarity between two Doppler images is then judged by recovering the alignment transform using a variant of dynamic shape warping. Results of similarity retrieval of doppler images for cardiac decision support on a large database of images are presented.

血流多普勒成像已成为超声心动图检查不可或缺的一部分。迄今为止,对血流多普勒成像的自动解读仅限于从这些图像中描述的速度-时间曲线中获取血液动力学信息。在本文中,我们利用多普勒图像中的形状模式来推断瓣膜疾病标签的相似性,从而实现自动临床决策支持的目的。具体来说,我们将同一疾病类别的多普勒图像的外观相似性建模为这些图像中嵌入的速度包络线的约束非刚性平移变换。然后,通过使用动态形状扭曲变体恢复对齐变换来判断两幅多普勒图像的形状相似性。本文介绍了在大型图像数据库中进行多普勒图像相似性检索以支持心脏决策的结果。
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引用次数: 0
Diffeomorphic Sulcal Shape Analysis for Cortical Surface Registration. 脑皮层表面配准的微分形沟形分析。
Shantanu H Joshi, Ryan P Cabeen, Anand A Joshi, Roger P Woods, Katherine L Narr, Arthur W Toga

We present an intrinsic framework for constructing sulcal shape atlases on the human cortex. We propose the analysis of sulcal and gyral patterns by representing them by continuous open curves in ℝ(3). The space of such curves, also termed as the shape manifold is equipped with a Riemannian L(2) metric on the tangent space, and shows desirable properties while matching shapes of sulci. On account of the spherical nature of the shape space, geodesics between shapes can be computed analytically. Additionally, we also present an optimization approach that computes geodesics in the quotient space of shapes modulo rigid rotations and reparameterizations. We also integrate the elastic shape model into a surface registration framework for a population of 176 subjects, and show a considerable improvement in the constructed surface atlases.

我们提出了一个内在的框架来构建人类皮层的沟形状地图集。我们提出了用连续开曲线表示的方法来分析槽型和旋型。这种曲线的空间,也称为形状流形,在切空间上配备了黎曼L(2)度量,并在匹配沟的形状时显示出理想的性质。由于形状空间的球形性质,可以解析地计算形状之间的测地线。此外,我们还提出了一种在模刚性旋转和重参数化的形状商空间中计算测地线的优化方法。我们还将弹性形状模型集成到176个受试者的表面配准框架中,并在构建的表面地图集中显示出相当大的改进。
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引用次数: 5
Learning Kernels for variants of Normalized Cuts: Convex Relaxations and Applications. 学习归一化切割变体的核:凸松弛及其应用。
Lopamudra Mukherjee, Vikas Singh, Jiming Peng, Chris Hinrichs

We propose a new algorithm for learning kernels for variants of the Normalized Cuts (NCuts) objective - i.e., given a set of training examples with known partitions, how should a basis set of similarity functions be combined to induce NCuts favorable distributions. Such a procedure facilitates design of good affinity matrices. It also helps assess the importance of different feature types for discrimination. Rather than formulating the learning problem in terms of the spectral relaxation, the alternative we pursue here is to work in the original discrete setting (i.e., the relaxation occurs much later). We show that this strategy is useful - while the initial specification seems rather difficult to optimize efficiently, a set of manipulations reveal a related model which permits a nice SDP relaxation. A salient feature of our model is that the eventual problem size is only a function of the number of input kernels and not the training set size. This relaxation also allows strong optimality guarantees, if certain conditions are satisfied. We show that the sub-kernel weights obtained provide a complementary approach for MKL based methods. Our experiments on Caltech101 and ADNI (a brain imaging dataset) show that the quality of solutions is competitive with the state-of-the-art.

我们提出了一种新的算法来学习归一化切割(NCuts)目标变体的核——即给定一组已知分区的训练样例,如何组合一组相似函数来诱导NCuts有利分布。这样的程序有利于设计良好的亲和矩阵。它还有助于评估不同特征类型对识别的重要性。而不是在谱松弛方面制定学习问题,我们在这里追求的替代方案是在原始离散设置中工作(即,松弛发生得更晚)。我们证明了这个策略是有用的——虽然最初的规范似乎很难有效地优化,但一组操作揭示了一个相关的模型,该模型允许很好的SDP松弛。我们模型的一个显著特征是,最终的问题大小只是输入核数的函数,而不是训练集大小的函数。如果满足某些条件,这种放松也允许强最优性保证。我们证明,获得的子核权重为基于MKL的方法提供了一种补充方法。我们在Caltech101和ADNI(一个脑成像数据集)上的实验表明,解决方案的质量与最先进的解决方案具有竞争力。
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引用次数: 9
Total Bregman Divergence and its Applications to Shape Retrieval. 布雷格曼总发散及其在形状检索中的应用
Meizhu Liu, Baba C Vemuri, Shun-Ichi Amari, Frank Nielsen

Shape database search is ubiquitous in the world of biometric systems, CAD systems etc. Shape data in these domains is experiencing an explosive growth and usually requires search of whole shape databases to retrieve the best matches with accuracy and efficiency for a variety of tasks. In this paper, we present a novel divergence measure between any two given points in [Formula: see text] or two distribution functions. This divergence measures the orthogonal distance between the tangent to the convex function (used in the definition of the divergence) at one of its input arguments and its second argument. This is in contrast to the ordinate distance taken in the usual definition of the Bregman class of divergences [4]. We use this orthogonal distance to redefine the Bregman class of divergences and develop a new theory for estimating the center of a set of vectors as well as probability distribution functions. The new class of divergences are dubbed the total Bregman divergence (TBD). We present the l1-norm based TBD center that is dubbed the t-center which is then used as a cluster center of a class of shapes The t-center is weighted mean and this weight is small for noise and outliers. We present a shape retrieval scheme using TBD and the t-center for representing the classes of shapes from the MPEG-7 database and compare the results with other state-of-the-art methods in literature.

在生物识别系统和 CAD 系统等领域,形状数据库搜索无处不在。这些领域中的形状数据正经历着爆炸式增长,通常需要搜索整个形状数据库,才能在各种任务中准确高效地检索出最佳匹配结果。在本文中,我们提出了[公式:见正文]中任意两个给定点或两个分布函数之间的新型发散度量。这种发散度量的是凸函数切线(用于发散度量的定义)在其输入参数之一与第二个参数之间的正交距离。这与布雷格曼发散类的通常定义中采用的正交距离不同[4]。我们利用这个正交距离重新定义了 Bregman 发散类,并发展出一套新理论,用于估计一组向量的中心以及概率分布函数。新的发散类被称为总布雷格曼发散(TBD)。我们提出了基于 l1 准则的 TBD 中心,并将其称为 t 中心,然后将其用作一类形状的聚类中心。我们介绍了一种使用 TBD 和 t-中心来表示 MPEG-7 数据库中的形状类别的形状检索方案,并将结果与文献中其他最先进的方法进行了比较。
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引用次数: 0
Shape Comparison Using Perturbing Shape Registration. 使用扰动形状配准的形状比较。
Yifeng Jiang, Erin Edmiston, Fei Wang, Hilary P Blumberg, Lawrence H Staib, Xenophon Papademetris

Shape registration is often involved in computing statistical differences between groups of shapes, which is a key aspect of morphometric study. The results of shape difference are found to be sensitive to registration, i.e., different registration methods lead to varied results. This raises the question of how to improve the reliability of registration procedures. This paper proposes a perturbation scheme, which perturbs registrations by feeding them with different resampled shape groups, and then aggregates the resulting shape differences. Experiments are conducted using three typical registration algorithms on both synthetic and biomedical shapes, where more reliable inter-group shape differences are found under the proposed scheme.

形状配准通常涉及到计算形状组之间的统计差异,这是形态计量学研究的一个关键方面。发现形状差异的结果对配准很敏感,即不同的配准方法会导致不同的结果。这就提出了如何提高登记程序可靠性的问题。本文提出了一种摄动方案,通过输入不同的重采样形状组对配准进行摄动,然后将得到的形状差异进行聚合。采用三种典型的配准算法对合成形状和生物医学形状进行了实验,在实验中发现了更可靠的组间形状差异。
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引用次数: 0
Continuous Maximal Flows and Wulff Shapes: Application to MRFs. 连续最大流和Wulff形状:在mrf中的应用。
Christopher Zach, Marc Niethammer, Jan-Michael Frahm

Convex and continuous energy formulations for low level vision problems enable efficient search procedures for the corresponding globally optimal solutions. In this work we extend the well-established continuous, isotropic capacity-based maximal flow framework to the anisotropic setting. By using powerful results from convex analysis, a very simple and efficient minimization procedure is derived. Further, we show that many important properties carry over to the new anisotropic framework, e.g. globally optimal binary results can be achieved simply by thresholding the continuous solution. In addition, we unify the anisotropic continuous maximal flow approach with a recently proposed convex and continuous formulation for Markov random fields, thereby allowing more general smoothness priors to be incorporated. Dense stereo results are included to illustrate the capabilities of the proposed approach.

低水平视觉问题的凸型和连续型能量公式能够有效地搜索到相应的全局最优解。在这项工作中,我们将已建立的连续的、各向同性的基于容量的最大流量框架扩展到各向异性设置。利用凸分析的强大结果,导出了一个非常简单有效的最小化程序。此外,我们证明了许多重要的性质延续到新的各向异性框架,例如,全局最优的二进制结果可以简单地通过阈值连续解来实现。此外,我们将各向异性连续最大流方法与最近提出的马尔可夫随机场的凸和连续公式统一起来,从而允许纳入更一般的平滑先验。密集立体结果包括,以说明所提出的方法的能力。
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引用次数: 43
Optimization of Landmark Selection for Cortical Surface Registration. 皮质表面配准中地标选择的优化。
Anand Joshi, Dimitrios Pantazis, Hanna Damasio, David Shattuck, Quanzheng Li, Richard Leahy

Manually labeled landmark sets are often required as inputs for landmark-based image registration. Identifying an optimal subset of landmarks from a training dataset may be useful in reducing the labor intensive task of manual labeling. In this paper, we present a new problem and a method to solve it: given a set of N landmarks, find the k(< N) best landmarks such that aligning these k landmarks that produce the best overall alignment of all N landmarks. The resulting procedure allows us to select a reduced number of landmarks to be labeled as a part of the registration procedure. We apply this methodology to the problem of registering cerebral cortical surfaces extracted from MRI data. We use manually traced sulcal curves as landmarks in performing inter-subject registration of these surfaces. To minimize the error metric, we analyze the correlation structure of the sulcal errors in the landmark points by modeling them as a multivariate Gaussian process. Selection of the optimal subset of sulcal curves is performed by computing the error variance for the subset of unconstrained landmarks conditioned on the constrained set. We show that the registration error predicted by our method closely matches the actual registration error. The method determines optimal curve subsets of any given size with minimal registration error.

基于地标的图像配准通常需要人工标记的地标集作为输入。从训练数据集中识别一个最优的地标子集可能有助于减少人工标记的劳动密集型任务。在本文中,我们提出了一个新的问题和解决方法:给定一组N个地标,找出k(< N)个最佳地标,使这k个地标对齐,从而产生所有N个地标的最佳整体对齐。由此产生的程序允许我们选择减少数量的地标作为注册程序的一部分进行标记。我们将这种方法应用于从MRI数据中提取的大脑皮层表面的注册问题。我们使用手动跟踪沟曲线作为地标,在执行这些表面的主体间注册。为了最小化误差度量,我们通过将其建模为多元高斯过程来分析地标点的沟误差的相关结构。通过计算以约束集为条件的无约束地标子集的误差方差来选择沟槽曲线的最优子集。结果表明,该方法预测的配准误差与实际配准误差接近。该方法以最小的配准误差确定任意大小的最优曲线子集。
{"title":"Optimization of Landmark Selection for Cortical Surface Registration.","authors":"Anand Joshi,&nbsp;Dimitrios Pantazis,&nbsp;Hanna Damasio,&nbsp;David Shattuck,&nbsp;Quanzheng Li,&nbsp;Richard Leahy","doi":"10.1109/CVPR.2009.5206560","DOIUrl":"https://doi.org/10.1109/CVPR.2009.5206560","url":null,"abstract":"<p><p>Manually labeled landmark sets are often required as inputs for landmark-based image registration. Identifying an optimal subset of landmarks from a training dataset may be useful in reducing the labor intensive task of manual labeling. In this paper, we present a new problem and a method to solve it: given a set of N landmarks, find the k(< N) best landmarks such that aligning these k landmarks that produce the best overall alignment of all N landmarks. The resulting procedure allows us to select a reduced number of landmarks to be labeled as a part of the registration procedure. We apply this methodology to the problem of registering cerebral cortical surfaces extracted from MRI data. We use manually traced sulcal curves as landmarks in performing inter-subject registration of these surfaces. To minimize the error metric, we analyze the correlation structure of the sulcal errors in the landmark points by modeling them as a multivariate Gaussian process. Selection of the optimal subset of sulcal curves is performed by computing the error variance for the subset of unconstrained landmarks conditioned on the constrained set. We show that the registration error predicted by our method closely matches the actual registration error. The method determines optimal curve subsets of any given size with minimal registration error.</p>","PeriodicalId":74560,"journal":{"name":"Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition","volume":"20-25 ","pages":"699-706"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/CVPR.2009.5206560","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29194140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Cortical Enhanced Tissue Segmentation of Neonatal Brain MR Images Acquired by a Dedicated Phased Array Coil. 专用相控阵线圈获取新生儿脑MR图像的皮质增强组织分割。
Feng Shi, Pew-Thian Yap, Yong Fan, Jie-Zhi Cheng, Lawrence L Wald, Guido Gerig, Weili Lin, Dinggang Shen

The acquisition of high quality MR images of neonatal brains is largely hampered by their characteristically small head size and low tissue contrast. As a result, subsequent image processing and analysis, especially for brain tissue segmentation, are often hindered. To overcome this problem, a dedicated phased array neonatal head coil is utilized to improve MR image quality by effectively combing images obtained from 8 coil elements without lengthening data acquisition time. In addition, a subject-specific atlas based tissue segmentation algorithm is specifically developed for the delineation of fine structures in the acquired neonatal brain MR images. The proposed tissue segmentation method first enhances the sheet-like cortical gray matter (GM) structures in neonatal images with a Hessian filter for generation of cortical GM prior. Then, the prior is combined with our neonatal population atlas to form a cortical enhanced hybrid atlas, which we refer to as the subject-specific atlas. Various experiments are conducted to compare the proposed method with manual segmentation results, as well as with additional two population atlas based segmentation methods. Results show that the proposed method is capable of segmenting the neonatal brain with the highest accuracy, compared to other two methods.

新生儿脑部的高质量磁共振图像的获取在很大程度上受到其特征性的小头部尺寸和低组织对比度的阻碍。因此,后续的图像处理和分析,特别是脑组织分割,往往受到阻碍。为了克服这一问题,利用专用的相控阵新生儿头部线圈,在不延长数据采集时间的情况下,有效地将8个线圈单元获得的图像进行组合,从而提高MR图像质量。此外,我们还开发了一种基于主题特异性图谱的组织分割算法,用于描绘获得性新生儿脑MR图像中的精细结构。提出的组织分割方法首先利用Hessian滤波器对新生儿图像中的片状皮质灰质(GM)结构进行增强。然后,先验与我们的新生儿种群图谱相结合,形成皮质增强杂交图谱,我们称之为主题特异性图谱。进行了各种实验,将该方法与人工分割结果以及另外两种基于种群图谱的分割方法进行了比较。结果表明,与其他两种方法相比,该方法能够以最高的准确率对新生儿大脑进行分割。
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引用次数: 0
Half-Integrality based Algorithms for Cosegmentation of Images. 基于半完整性的图像共分割算法。
Lopamudra Mukherjee, Vikas Singh, Charles R Dyer

We study the cosegmentation problem where the objective is to segment the same object (i.e., region) from a pair of images. The segmentation for each image can be cast using a partitioning/segmentation function with an additional constraint that seeks to make the histograms of the segmented regions (based on intensity and texture features) similar. Using Markov Random Field (MRF) energy terms for the simultaneous segmentation of the images together with histogram consistency requirements using the squared L(2) (rather than L(1)) distance, after linearization and adjustments, yields an optimization model with some interesting combinatorial properties. We discuss these properties which are closely related to certain relaxation strategies recently introduced in computer vision. Finally, we show experimental results of the proposed approach.

我们研究了共分割问题,其目标是从一对图像中分割相同的物体(即区域)。每个图像的分割可以使用带有附加约束的分区/分割函数进行,该函数寻求使分割区域的直方图(基于强度和纹理特征)相似。在线性化和调整后,使用马尔科夫随机场(MRF)能量项对图像进行同时分割,并使用平方L(2)(而不是L(1))距离的直方图一致性要求,产生具有一些有趣组合特性的优化模型。我们讨论了这些性质,它们与最近在计算机视觉中引入的某些松弛策略密切相关。最后,给出了该方法的实验结果。
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引用次数: 0
Anisotropic Laplace-Beltrami Eigenmaps: Bridging Reeb Graphs and Skeletons. 各向异性拉普拉斯-贝尔特拉米特征图:桥接Reeb图和骨架。
Yonggang Shi, Rongjie Lai, Sheila Krishna, Nancy Sicotte, Ivo Dinov, Arthur W Toga

In this paper we propose a novel approach of computing skeletons of robust topology for simply connected surfaces with boundary by constructing Reeb graphs from the eigenfunctions of an anisotropic Laplace-Beltrami operator. Our work brings together the idea of Reeb graphs and skeletons by incorporating a flux-based weight function into the Laplace-Beltrami operator. Based on the intrinsic geometry of the surface, the resulting Reeb graph is pose independent and captures the global profile of surface geometry. Our algorithm is very efficient and it only takes several seconds to compute on neuroanatomical structures such as the cingulate gyrus and corpus callosum. In our experiments, we show that the Reeb graphs serve well as an approximate skeleton with consistent topology while following the main body of conventional skeletons quite accurately.

本文利用各向异性Laplace-Beltrami算子的特征函数构造Reeb图,提出了一种计算具有边界的单连通曲面鲁棒拓扑骨架的新方法。我们的工作通过将基于通量的权重函数合并到Laplace-Beltrami算子中,将Reeb图和骨架的思想结合在一起。基于表面的固有几何特性,生成的Reeb图是位姿无关的,并且捕获了表面几何的全局轮廓。我们的算法非常高效,在扣带回和胼胝体等神经解剖结构上只需要几秒钟的计算时间。在我们的实验中,我们表明Reeb图可以很好地作为具有一致拓扑的近似骨架,同时非常准确地遵循传统骨架的主体。
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引用次数: 72
期刊
Proceedings. IEEE Computer Society Conference on Computer Vision and Pattern Recognition
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