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Risk factors for postpartum hemorrhage according to the Robson classification in a low-risk maternity hospital. 一家低风险产科医院根据罗布森分类法得出的产后出血风险因素。
Amanda Botelho, Adriana Luckow Invitti, Rosiane Mattar, David Baptista da Silva Pares, Camilla Parente Salmeron, João Victor Jacomele Caldas, Nathalia Mello, Alberto Borges Peixoto, Edward Araujo Júnior, Sue Yazaki Sun

Objective: To evaluate the risk factors for postpartum hemorrhage (PPH) according to the Robson Classification in a low-risk maternity hospital.

Methods: We conducted retrospective cohort study by analyzing the medical records of pregnant women attended in a low-risk maternity hospital, during from November 2019 to November 2021. Variables analyzed were: maternal age, type of delivery, birth weight, parity, Robson Classification, and causes of PPH. We compared the occurrence of PPH between pregnant women with spontaneous (Groups 1 and 3) and with induction of labor (2a and 4a). Chi-square and Student t-tests were performed. Variables were compared using binary logistic regression.

Results: There were 11,935 deliveries during the study period. According to Robson's Classification, 48.2% were classified as 1 and 3 (Group I: 5,750/11,935) and 26.1% as 2a and 4a (Group II: 3,124/11,935). Group II had higher prevalence of PPH than Group I (3.5 vs. 2.7%, p=0.028). Labor induction increased the occurrence of PPH by 18.8% (RR: 1.188, 95% CI: 1.02-1.36, p=0.030). Model including forceps delivery [x2(3)=10.6, OR: 7.26, 95%CI: 3.32-15.84, R2 Nagelkerke: 0.011, p<0.001] and birth weight [x2(4)=59.0, OR: 1.001, 95%CI:1.001-1.001, R2 Nagelkerke: 0.033, p<0.001] was the best for predicting PPH in patients classified as Robson 1, 3, 2a, and 4a. Birth weight was poor predictor of PPH (area under ROC curve: 0.612, p<0.001, 95%CI: 0.572-0.653).

Conclusion: Robson Classification 2a and 4a showed the highest rates of postpartum hemorrhage. The model including forceps delivery and birth weight was the best predictor for postpartum hemorrhage in Robson Classification 1, 3, 2a, and 4a.

目的:根据罗布森分类法评估低风险产科医院产后出血(PPH)的风险因素:根据罗布森分类法评估低风险产科医院产后出血(PPH)的风险因素:我们通过分析一家低风险妇产医院 2019 年 11 月至 2021 年 11 月期间就诊孕妇的病历,开展了一项回顾性队列研究。分析的变量包括:产妇年龄、分娩类型、出生体重、胎次、罗布森分类和 PPH 的原因。我们比较了自然分娩(第 1 组和第 3 组)和引产(第 2a 组和第 4a 组)孕妇的 PPH 发生率。进行了卡方检验和学生 t 检验。使用二元逻辑回归对变量进行比较:研究期间共有 11,935 例分娩。根据罗布森分类法,48.2%的产妇被分为 1 和 3 类(第一组:5 750/11 935 例),26.1%的产妇被分为 2a 和 4a 类(第二组:3 124/11 935 例)。第二组的 PPH 发生率高于第一组(3.5% 对 2.7%,P=0.028)。引产使 PPH 发生率增加了 18.8%(RR:1.188,95% CI:1.02-1.36,P=0.030)。包括产钳分娩的模型[x2(3)=10.6,OR:7.26,95%CI:3.32-15.84,R2 Nagelkerke:0.011,p2(4)=59.0,OR:1.001,95%CI:1.001-1.001,R2 Nagelkerke:0.033,p结论:罗布森分级 2a 和 4a 显示了最高的产后出血率。包括产钳助产和出生体重在内的模型是预测罗布森分级 1、3、2a 和 4a 产后出血的最佳指标。
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引用次数: 0
The profile of patients with postpartum hemorrhage admitted to the obstetric intensive care: a cross-sectional study. 产科重症监护室收治的产后出血患者概况:一项横断面研究。
Mayara Dos Santos Farias Ferreira Silva, Melania Maria Ramos de Amorim, Brena Melo, André Vieira Lanza, Maria Eduarda Trigueiro Ramos, Bruna Antunes Durães de Carvalho, Natalia Nunes Tenório, Leila Katz

Objective: In Brazil, postpartum hemorrhage (PPH) is a major cause of maternal morbidity and mortality. Data on the profile of women and risk factors associated with PPH are sparse. This study aimed to describe the profile and management of patients with PPH, and the association of risk factors for PPH with severe maternal outcomes (SMO).

Methods: A cross-sectional study was conducted in Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) obstetric intensive care unit (ICU) between January 2012 and March 2020, including patients who gave birth at the hospital and that were admitted with PPH to the ICU.

Results: The study included 358 patients, of whom 245 (68.4%) delivered in the IMIP maternity, and 113 (31.6%) in other maternity. The mean age of the patients was 26.7 years, with up to eight years of education (46.1%) and a mean of six prenatal care. Uterine atony (72.9%) was the most common cause, 1.6% estimated blood loss, 2% calculated shock index (SI), 63.9% of patients received hemotransfusion, and 27% underwent hysterectomy. 136 cases of SMO were identified, 35.5% were classified as maternal near miss and 3.0% maternal deaths. Multiparity was associated with SMO as an antepartum risk factor (RR=1.83, 95% CI1.42-2.36). Regarding intrapartum risk factors, abruptio placentae abruption was associated with SMO (RR=2.2 95% CI1.75-2.81). Among those who had hypertension (49.6%) there was a lower risk of developing SMO.

Conclusion: The principal factors associated with poor maternal outcome were being multiparous and placental abruption.

目的:在巴西,产后出血(PPH)是孕产妇发病和死亡的主要原因。有关产妇概况和 PPH 相关风险因素的数据很少。本研究旨在描述 PPH 患者的概况和管理情况,以及 PPH 风险因素与严重产妇结局(SMO)之间的关联:2012年1月至2020年3月期间,费尔南多-费盖拉教授综合医学院(IMIP)产科重症监护室(ICU)开展了一项横断面研究,研究对象包括在该院分娩并因PPH入住重症监护室的患者:研究共纳入358名患者,其中245人(68.4%)在IMIP产科医院分娩,113人(31.6%)在其他产科医院分娩。患者的平均年龄为 26.7 岁,接受过最多 8 年的教育(46.1%),平均接受过 6 次产前护理。子宫弛缓(72.9%)是最常见的原因,1.6%估计失血量,2%计算休克指数(SI),63.9%的患者接受了输血,27%接受了子宫切除术。共发现 136 例 SMO,35.5% 被归类为产妇险情,3.0% 的产妇死亡。作为产前风险因素,多胎妊娠与 SMO 相关(RR=1.83,95% CI1.42-2.36)。关于产前风险因素,胎盘早剥与 SMO 有关(RR=2.2,95% CI1.75-2.81)。高血压患者(49.6%)发生 SMO 的风险较低:结论:与产妇不良预后相关的主要因素是多产妇和胎盘早剥。
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引用次数: 0
Prevalence of macrosomic newborn and maternal and neonatal complications in a high-risk maternity. 高危产妇中巨型新生儿的发病率以及产妇和新生儿并发症。
Kellen Silva Sousa, Henrique Vitor Leite, Mário Dias Corrêa, Matheus Silva Sousa, Anna Luíza Rocha Queiroz

Objective: Evaluate the prevalence of macrosomic newborns (birth weight above 4000 grams) in a high-risk maternity from 2014 to 2019, as well as the maternal characteristics involved, risk factors, mode of delivery and associated outcomes, comparing newborns weighing 4000-4500 grams and those weighing above 4500 grams.

Methods: This is an observational study, case-control type, carried out by searching for data in hospital's own system and clinical records. The criteria for inclusion in the study were all patients monitored at the service who had newborns with birth weight equal than or greater than 4000 grams in the period from January 2014 to December 2019, being subsequently divided into two subgroups (newborns with 4000 to 4500 grams and newborns above 4500 grams). After being collected, the variables were transcribed into a database, arranged in frequency tables. For treatment and statistical analysis of the data, Excel and R software were used. This tool was used to create graphs and tables that helped in the interpretation of the results. The statistical analysis of the variables collected included both simple descriptive analyzes as well as inferential statistics, with univariate, bivariate and multivariate analysis.

Results: From 2014 to 2019, 3.3% of deliveries were macrosomic newborns. The average gestational age in the birth was 39.4 weeks. The most common mode of delivery (65%) was cesarean section. Diabetes mellitus was present in 30% of the deliveries studied and glycemic control was absent in most patients. Among the vaginal deliveries, only 6% were instrumented and there was shoulder dystocia in 21% of the cases. The majority (62%) of newborns had some complication, with jaundice (35%) being the most common.

Conclusion: Birth weight above 4000 grams had a statistically significant impact on the occurrence of neonatal complications, such as hypoglycemia, respiratory distress and 5th minute APGAR less than 7, especially if birth weight was above 4500 grams. Gestational age was also shown to be statistically significant associated with neonatal complications, the lower, the greater the risk. Thus, macrosomia is strongly linked to complications, especially neonatal complications.

目的评估 2014 年至 2019 年高危孕产妇中巨型新生儿(出生体重超过 4000 克)的发生率,以及所涉及的孕产妇特征、风险因素、分娩方式和相关结果,比较体重 4000-4500 克的新生儿和体重 4500 克以上的新生儿:这是一项病例对照型观察研究,通过搜索医院自身系统和临床记录中的数据进行。纳入研究的标准是在2014年1月至2019年12月期间,在该服务机构接受监测的所有新生儿出生体重等于或大于4000克的患者,随后分为两个亚组(4000至4500克的新生儿和4500克以上的新生儿)。收集后,变量被转录到数据库中,并以频数表的形式排列。数据处理和统计分析使用 Excel 和 R 软件。该工具用于创建图表,有助于解释结果。对所收集变量的统计分析既包括简单的描述性分析,也包括推理统计,包括单变量、双变量和多变量分析:从2014年到2019年,3.3%的分娩为巨大儿。平均胎龄为 39.4 周。最常见的分娩方式(65%)是剖腹产。在所研究的分娩中,30%的产妇患有糖尿病,大多数患者的血糖没有得到控制。在阴道分娩中,只有 6% 的产妇使用了器械,21% 的产妇发生了肩难产。大多数新生儿(62%)有一些并发症,其中黄疸(35%)是最常见的并发症:结论:出生体重超过 4000 克对新生儿并发症的发生有显著的统计学影响,如低血糖、呼吸窘迫和第 5 分钟 APGAR 低于 7,尤其是出生体重超过 4500 克的新生儿。胎龄与新生儿并发症也有显著的统计学相关性,胎龄越小,风险越大。因此,巨大儿与并发症尤其是新生儿并发症密切相关。
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引用次数: 0
The impact of a breast cancer diagnosis on marital outcomes and factors associated with divorce and separation. 乳腺癌诊断对婚姻结果的影响以及与离婚和分居相关的因素。
Gustavo Werutsky, Mahira Lopes, Rafaela Gomes de Jesus, Antonia Angeli Gazola, Rodrigo Azevedo Pellegrini, Taiane Francieli Rebelatto, Laura von Wallwitz Freitas, Ana Paula Heck, Arthur Ferreira da Silva, Matheus Füehr Rodrigues, Gustavo Gössling, Juliana Giacomazzi, Matheus Soares Rocha, Daniela Dornelles Rosa, Carlos Henrique Barrios, Eduardo Henrique Cronemberger, Geraldo Silva Queiroz, José Bines, Sérgio Daniel Simon, Andre Poisl Fay

Objective: To analyze marital outcomes, divorce or separation, and its association with demographic, socioeconomic, and clinicopathological factors among breast cancer (BC) survivors after 2-years of diagnosis.

Methods: We performed a retrospective analysis of marital status at baseline and at years 1 and 2 of follow-up of women aged ≥ 18 years diagnosed with invasive BC participating in the AMAZONA III (GBECAM0115) study. The BC diagnosis occurred between January 2016 and March 2018 at 23 institutions in Brazil.

Results: Of the 2974 women enrolled in AMAZONA III, 599 were married or living under common law at baseline. Divorce or separation occurred in 35 (5.8%) patients at 2 years of follow-up. In the multivariate analysis, public health insurance coverage was associated with a higher risk of marital status change (8.25% vs. 2.79%, RR 3.09, 95% CI 1.39 - 7.03, p = 0.007). Women who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation (8.1% vs. 4.49%, RR 1.97, 95 CI 1.04 - 3.72, p = 0.0366) than those who underwent breast-conserving surgery.

Conclusion: Women covered by the public health system and those who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation. This evidence further supports the idea that long-term marital stability is associated with a complex interplay between socioeconomic conditions and stressors, such as BC diagnosis and treatment. ClinicalTrials Registration: NCT02663973.

摘要分析乳腺癌(BC)幸存者在确诊两年后的婚姻状况、离婚或分居及其与人口、社会经济和临床病理因素的关系:我们对参与 AMAZONA III (GBECAM0115)研究的年龄≥18 岁、确诊为浸润性乳腺癌的女性在基线及随访第 1 年和第 2 年的婚姻状况进行了回顾性分析。BC诊断发生在2016年1月至2018年3月期间,在巴西的23家机构进行:在参加 AMAZONA III 的 2974 名女性中,有 599 人在基线时已婚或按照普通法生活。随访2年时有35名患者(5.8%)离婚或分居。在多变量分析中,公共医疗保险与较高的婚姻状况变化风险相关(8.25% vs. 2.79%,RR 3.09,95% CI 1.39 - 7.03,p = 0.007)。与接受保乳手术的妇女相比,接受乳房切除术、腺瘤切除术或保皮乳房切除术的妇女离婚或分居的风险更高(8.1% vs. 4.49%,RR 1.97,95 CI 1.04 - 3.72,p = 0.0366):结论:公共医疗系统覆盖的妇女以及接受乳房切除术、腺瘤切除术或保皮乳房切除术的妇女离婚或分居的风险较高。这一证据进一步支持了以下观点,即长期的婚姻稳定性与社会经济条件和压力因素(如乳腺癌的诊断和治疗)之间复杂的相互作用有关。临床试验注册:NCT02663973。
{"title":"The impact of a breast cancer diagnosis on marital outcomes and factors associated with divorce and separation.","authors":"Gustavo Werutsky, Mahira Lopes, Rafaela Gomes de Jesus, Antonia Angeli Gazola, Rodrigo Azevedo Pellegrini, Taiane Francieli Rebelatto, Laura von Wallwitz Freitas, Ana Paula Heck, Arthur Ferreira da Silva, Matheus Füehr Rodrigues, Gustavo Gössling, Juliana Giacomazzi, Matheus Soares Rocha, Daniela Dornelles Rosa, Carlos Henrique Barrios, Eduardo Henrique Cronemberger, Geraldo Silva Queiroz, José Bines, Sérgio Daniel Simon, Andre Poisl Fay","doi":"10.61622/rbgo/2024rbgo60","DOIUrl":"10.61622/rbgo/2024rbgo60","url":null,"abstract":"<p><strong>Objective: </strong>To analyze marital outcomes, divorce or separation, and its association with demographic, socioeconomic, and clinicopathological factors among breast cancer (BC) survivors after 2-years of diagnosis.</p><p><strong>Methods: </strong>We performed a retrospective analysis of marital status at baseline and at years 1 and 2 of follow-up of women aged ≥ 18 years diagnosed with invasive BC participating in the AMAZONA III (GBECAM0115) study. The BC diagnosis occurred between January 2016 and March 2018 at 23 institutions in Brazil.</p><p><strong>Results: </strong>Of the 2974 women enrolled in AMAZONA III, 599 were married or living under common law at baseline. Divorce or separation occurred in 35 (5.8%) patients at 2 years of follow-up. In the multivariate analysis, public health insurance coverage was associated with a higher risk of marital status change (8.25% vs. 2.79%, RR 3.09, 95% CI 1.39 - 7.03, p = 0.007). Women who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation (8.1% vs. 4.49%, RR 1.97, 95 CI 1.04 - 3.72, p = 0.0366) than those who underwent breast-conserving surgery.</p><p><strong>Conclusion: </strong>Women covered by the public health system and those who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation. This evidence further supports the idea that long-term marital stability is associated with a complex interplay between socioeconomic conditions and stressors, such as BC diagnosis and treatment. <b>ClinicalTrials Registration:</b> NCT02663973.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"46 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevention, diagnosis, and treatment protocol of dengue during pregnancy and the postpartum period. 孕期和产后登革热的预防、诊断和治疗方案。
Geraldo Duarte, Antonio Rodrigues Braga, Regis Kreitchmann, Maria Luiza Bezerra Menezes, Angélica Espinosa Barbosa Miranda, Ana Gabriela Alvares Travassos, Patrícia Pereira Dos Santos Melli, Roseli Mieko Yamamoto Nomura, Agnaldo Lopes da Silva, Maria Celeste Osório Wender
{"title":"Prevention, diagnosis, and treatment protocol of dengue during pregnancy and the postpartum period.","authors":"Geraldo Duarte, Antonio Rodrigues Braga, Regis Kreitchmann, Maria Luiza Bezerra Menezes, Angélica Espinosa Barbosa Miranda, Ana Gabriela Alvares Travassos, Patrícia Pereira Dos Santos Melli, Roseli Mieko Yamamoto Nomura, Agnaldo Lopes da Silva, Maria Celeste Osório Wender","doi":"10.61622/rbgo/2024rbgo73","DOIUrl":"10.61622/rbgo/2024rbgo73","url":null,"abstract":"","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"46 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual function in women with endometriosis and pelvic floor myofascial pain syndrome. 患有子宫内膜异位症和盆底肌筋膜疼痛综合征的妇女的性功能。
Rayanne Moreira da Cunha, Mariana Oliveira Veloso, Samuel Soares Coutinho, Luana Darc de Menezes Braga, Adriana Silva de Barros, Germana Mesquita Magalhães, Pedro Olavo de Paula Lima, Simony Lira do Nascimento, Leonardo Robson Pinheiro Sobreira Bezerra

Objective: To evaluate and compare the sexual function and pelvic floor muscles (PFM) function of women with endometriosis and chronic pelvic pain (CPP) with and without Myofascial Pelvic Pain Syndrome (MPPS).

Methods: Cross-sectional study conducted between January 2018 and December 2020. Women with deep endometriosis underwent assessments for trigger points (TP) and PFM function using the PERFECT scale. Electromyographic activity (EMG) and sexual function through Female Sexual Function Index (FSFI) were assessed. Statistical analyses included chi-square and Mann-Whitney tests.

Results: There were 46 women. 47% had increased muscle tone and 67% related TP in levator ani muscle (LAM). Weakness in PFM, with P≤2 was noted in 82% and P≥3 in only 17%. Incomplete relaxation of PFM presented in 30%. EMG results were resting 6.0, maximal voluntary isometric contraction (MVIC) 61.9 and Endurance 14.2; FSFI mean total score 24.7. We observed an association between increased muscle tone (P<.001), difficulty in relaxation (P=.019), and lower Endurance on EMG (P=.04) in women with TP in LAM. Participants with TP presented lower total FSFI score (P=.02). TP in the right OIM presented increased muscle tone (P=.01). TP in the left OIM presented lower values to function of PFM by PERFECT (P=.005), and in MVIC (P=.03) on EMG.

Conclusion: Trigger points (TP) in pelvic floor muscles (PFM) and obturator internus muscle (OIM) correlates with poorer PFM and sexual function, particularly in left OIM TP cases. Endometriosis and chronic pelvic pain raise muscle tone, weaken muscles, hinder relaxation, elevate resting electrical activity, lower maximum voluntary isometric contraction, and reduce PFM endurance.

目的评估和比较患有子宫内膜异位症和慢性盆腔痛(CPP)的妇女的性功能和盆底肌肉(PFM)功能,以及是否患有肌筋膜盆腔痛综合征(MPPS):横断面研究,时间为 2018 年 1 月至 2020 年 12 月。患有深部子宫内膜异位症的女性接受了触发点(TP)评估,并使用 PERFECT 量表评估了 PFM 功能。通过女性性功能指数(FSFI)评估肌电图活动(EMG)和性功能。统计分析包括卡方检验和曼-惠特尼检验:结果:46 名女性中,47% 的人肌张力增强,67% 的人肌张力下降。结果:46 名女性中,47% 的人肌张力增强,67% 的人与提肛肌 TP 有关。82%的人注意到提上睑肌无力,P≤2,只有17%的人注意到P≥3。30%的人出现 PFM 不完全松弛。肌电图结果为静息 6.0,最大自主等长收缩 (MVIC) 61.9,耐力 14.2;FSFI 平均总分 24.7。我们观察到,在 LAM 中患有 TP 的女性中,肌张力增加(PP=.019)与肌电图耐力降低(P=.04)之间存在关联。患有 TP 的参与者的 FSFI 总分较低(P=.02)。右侧 OIM 的 TP 表现为肌张力增加(P=.01)。左侧 OIM 中的 TP 在 PERFECT(P=.005)和肌电图 MVIC(P=.03)中显示出较低的 PFM 功能值:结论:盆底肌(PFM)和闭孔肌(OIM)的触发点(TP)与较差的盆底肌和性功能相关,尤其是在左侧闭孔肌触发点病例中。子宫内膜异位症和慢性盆腔疼痛会提高肌肉张力、削弱肌肉、阻碍肌肉放松、提高静息电活动、降低最大自主等长收缩力并降低盆底肌耐力。
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引用次数: 0
Laser therapy for genitourinary syndrome of menopause: systematic review and meta-analysis of randomized controlled trial. 更年期泌尿生殖系统综合征的激光疗法:随机对照试验的系统回顾和荟萃分析。
Lisieux de Lourdes Martins Nóbrega Pessoa, Amaxsell Thiago Barros de Souza, Ayane Cristine Alves Sarmento, Ana Paula Ferreira Costa, Isis Kelly Dos Santos, Eduardo Pereira de Azevedo, Kleyton Santos de Medeiros, Ana Katherine Gonçalves, Ricardo Ney Cobucci

Objective: This meta-analysis of randomized controlled trials (RCTs) aimed to update evidence on the effectiveness and safety of laser therapy for treating genitourinary syndrome of menopause (GSM).

Data sources: Manuscripts published until May 2023 were systematically searched in PubMed; Embase; Scopus; Web of Science; CENTRAL; CINAHL; and clinical trial databases (www.trialscentral.org, www.controlled-trials.com, and clinicaltrials.gov), with no language and year of publication restriction.

Studies selection: RCTs with women diagnosed with GSM, and the intervention was vaginal laser therapy (CO2-laser or Er: YAG-laser) comparing with placebo (sham therapy), no treatment or vaginal estrogen therapy.

Data collection: Two authors evaluated the publications for inclusion based on the title and abstract, followed by reviewing the relevant full-text articles. Disagreements during the review process were addressed by consensus, with the involvement of a third author.

Data synthesis: Twelve RCTs, representing a total of 5147 participants, were included in this review. Vaginal health index (VHI) significantly improved in the carbon dioxide laser (CO2-laser) therapy group (MD=2.21; 95% CI=1.25 to 3.16), while dyspareunia (MD=-0.85; 95% CI=-1.59 to -0.10), dryness (MD=-0.62; 95% CI=-1.12 to -0.12) and burning (MD= -0.64; 95% CI=-1.28 to -0.01) decreased. No serious adverse effects were reported.

Conclusion: CO2-laser increases VHI score and decreases dyspareunia, dryness and burning, especially when compared to sham-laser. However, the certainty of the evidence is low, thus preventing the recommendation of laser therapy for GSM management.

目的:对随机对照试验(RCT)进行荟萃分析:这项随机对照试验(RCTs)的荟萃分析旨在更新有关激光疗法治疗更年期泌尿生殖系统综合征(GSM)的有效性和安全性的证据:在PubMed、Embase、Scopus、Web of Science、CENTRAL、CINAHL和临床试验数据库(www.trialscentral.org、www.controlled-trials.com 和clinicaltrials.gov)中系统检索了截至2023年5月发表的稿件,没有语言和发表年份的限制:研究对象为确诊为 GSM 的女性,干预措施为阴道激光治疗(CO2 激光或 Er: YAG 激光),并与安慰剂(假治疗)、无治疗或阴道雌激素治疗进行比较:两位作者根据标题和摘要对出版物进行评估,然后审阅相关全文。在第三位作者的参与下,对审稿过程中出现的分歧达成共识:本次综述共纳入了 12 项研究性临床试验,共计 5147 名参与者。二氧化碳激光(CO2-laser)治疗组的阴道健康指数(VHI)明显改善(MD=2.21;95% CI=1.25至3.16),而排便困难(MD=-0.85;95% CI=-1.59至-0.10)、干涩(MD=-0.62;95% CI=-1.12至-0.12)和灼热(MD=-0.64;95% CI=-1.28至-0.01)有所减轻。无严重不良反应报告:结论:与假激光相比,二氧化碳激光可提高 VHI 分值,减少排便困难、干燥和灼热感。然而,证据的确定性较低,因此无法推荐将激光疗法用于 GSM 治疗。
{"title":"Laser therapy for genitourinary syndrome of menopause: systematic review and meta-analysis of randomized controlled trial.","authors":"Lisieux de Lourdes Martins Nóbrega Pessoa, Amaxsell Thiago Barros de Souza, Ayane Cristine Alves Sarmento, Ana Paula Ferreira Costa, Isis Kelly Dos Santos, Eduardo Pereira de Azevedo, Kleyton Santos de Medeiros, Ana Katherine Gonçalves, Ricardo Ney Cobucci","doi":"10.61622/rbgo/2024rbgo38","DOIUrl":"10.61622/rbgo/2024rbgo38","url":null,"abstract":"<p><strong>Objective: </strong>This meta-analysis of randomized controlled trials (RCTs) aimed to update evidence on the effectiveness and safety of laser therapy for treating genitourinary syndrome of menopause (GSM).</p><p><strong>Data sources: </strong>Manuscripts published until May 2023 were systematically searched in PubMed; Embase; Scopus; Web of Science; CENTRAL; CINAHL; and clinical trial databases (www.trialscentral.org, www.controlled-trials.com, and clinicaltrials.gov), with no language and year of publication restriction.</p><p><strong>Studies selection: </strong>RCTs with women diagnosed with GSM, and the intervention was vaginal laser therapy (CO2-laser or Er: YAG-laser) comparing with placebo (sham therapy), no treatment or vaginal estrogen therapy.</p><p><strong>Data collection: </strong>Two authors evaluated the publications for inclusion based on the title and abstract, followed by reviewing the relevant full-text articles. Disagreements during the review process were addressed by consensus, with the involvement of a third author.</p><p><strong>Data synthesis: </strong>Twelve RCTs, representing a total of 5147 participants, were included in this review. Vaginal health index (VHI) significantly improved in the carbon dioxide laser (CO2-laser) therapy group (MD=2.21; 95% CI=1.25 to 3.16), while dyspareunia (MD=-0.85; 95% CI=-1.59 to -0.10), dryness (MD=-0.62; 95% CI=-1.12 to -0.12) and burning (MD= -0.64; 95% CI=-1.28 to -0.01) decreased. No serious adverse effects were reported.</p><p><strong>Conclusion: </strong>CO2-laser increases VHI score and decreases dyspareunia, dryness and burning, especially when compared to sham-laser. However, the certainty of the evidence is low, thus preventing the recommendation of laser therapy for GSM management.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"46 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11460430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient positioning in minimally invasive gynecologic surgery: strategies to prevent injuries and improve outcomes. 微创妇科手术中的患者定位:预防损伤和提高疗效的策略。
Agnaldo Lopes da Silva, Matheus Eduardo Soares Pinhati, Gabriel Lage Neves, Eduarda Naves Gonçalves de Almeida, Teresa Lamaita Lopes, Rívia Mara Lamaita, Eduardo Batista Cândido

Effective patient positioning is a critical factor influencing surgical outcomes, mainly in minimally invasive gynecologic surgery (MIGS) where precise positioning facilitates optimal access to the surgical field. This paper provides a comprehensive exploration of the significance of strategic patient placement in MIGS, emphasizing its role in preventing intraoperative injuries and enhancing overall surgical success. The manuscript addresses potential complications arising from suboptimal positioning and highlights the essential key points for appropriate patient positioning during MIGS, encompassing what the surgical team should or shouldn't do. In this perspective, the risk factors associated with nerve injuries, sliding, compartment syndrome, and pressure ulcers are outlined to guide clinical practice. Overall, this paper underscores the critical role of precise patient positioning in achieving successful MIGS procedures and highlights key principles for the gynecological team to ensure optimal patient outcomes.

有效的患者定位是影响手术效果的关键因素,主要是在微创妇科手术(MIGS)中,精确的定位有助于最佳进入手术区域。本文全面探讨了在 MIGS 中对患者进行战略性安置的意义,强调了其在防止术中损伤和提高整体手术成功率方面的作用。手稿探讨了不理想的定位可能引起的并发症,并强调了在 MIGS 中对患者进行适当定位的基本要点,包括手术团队应该做什么或不应该做什么。从这个角度概述了与神经损伤、滑动、隔室综合症和压疮相关的风险因素,以指导临床实践。总之,本文强调了患者精确定位在成功完成 MIGS 手术中的关键作用,并强调了妇科团队确保患者获得最佳治疗效果的关键原则。
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引用次数: 0
Prediction and secondary prevention of preeclampsia from the perspective of public health management - the initiative of the State of Rio de Janeiro. 从公共卫生管理的角度预测和二级预防先兆子痫--里约热内卢州的倡议。
Antonio Braga, Penélope Saldanha Marinho, Marcos Nakamura-Pereira, José Carlos Peraçoli, Cláudia Mello
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引用次数: 0
Women's experiences with the post-placental intrauterine device: a qualitative study. 妇女使用胎盘植入后宫内节育器的经验:一项定性研究。
Ana Beatriz Venturin, Debora Bicudo Faria-Schützer, Odette Del Risco Sánchez, Larissa Rodrigues, Thuany Bento Herculano, Fernanda Garanhani Surita

Objective: To explore women's experiences with postpartum intrauterine device (PPIUD) insertion and the decision-making process in the postpartum period.

Methods: A qualitative design was employed with face-to-face interviews using a semi-structured script of open questions. The sample was intentionally selected using the concept of theoretical information saturation.

Results: Interviews were conducted (1) in the immediate postpartum period, and (2) in the postpartum appointment. 25 women (N = 25) over 18 years old who had a birth followed by PPIUD insertion were interviewed between October 2021 and June 2022. Three categories were constructed: (1) Choice process, (2) Relationship with the health team at the time of birth and the postpartum period, and (3) To know or not to know about contraception, that is the question.

Conclusion: Professionals' communication management, popular knowledge, advantages of the PPIUD and the moment PPIUD is offered play a fundamental role in the construction of knowledge about the IUD. Choice process did not end in the insertion.

目的探讨妇女产后放置宫内节育器(PPIUD)的经历以及产后的决策过程:采用半结构化开放式问题脚本进行面对面访谈的定性设计。采用理论信息饱和的概念有意选择样本:访谈(1)在产后初期进行,(2)在产后预约期间进行。在 2021 年 10 月至 2022 年 6 月期间,对 25 名年满 18 岁、分娩后放置 PPIUD 的妇女(N = 25)进行了访谈。我们构建了三个类别:(1)选择过程;(2)分娩时和产后与医疗团队的关系;(3)知道还是不知道避孕,这就是问题所在:结论:专业人员的沟通管理、普及知识、宫内节育器的优点以及提供宫内节育器的时机,在 构建宫内节育器知识的过程中发挥着重要作用。选择过程并不以插入宫内节育器为终点。
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引用次数: 0
期刊
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
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