首页 > 最新文献

Revista paulista de medicina最新文献

英文 中文
Gallbladder injuries due to blunt abdominal trauma: report on five cases and review of the literature. 钝性腹部创伤致胆囊损伤5例报告并文献复习。
Pub Date : 1992-11-01
L F Zantut, M A Machado, A L de Souza, P Volpe, A J Rodrigues Júnior, R S Poggetti, D Birolini

Gallbladder lesions by blunt abdominal trauma are rare, due to the organ's anatomical particularities. Diagnosis is difficult, and it generally occurs during surgery. The trauma is usually associated with other lesions and is related to very serious traumas or to deceleration. Due to the scarcity of publications on this topic and to its reduced incidence, we present here a report of five patients who had suffered blunt abdominal trauma with gallbladder lesion and who were attended at the General Hospital (of the University of São Paulo Medical School) Emergency Service between 1986 and 1991. Furthermore, we analyze the incidence of this trauma, presence of associated lesion, treatment, morbidity and mortality of the patients, as well as a review of the literature.

由于胆囊的解剖特点,钝性腹部创伤引起的胆囊病变是罕见的。诊断困难,通常发生在手术中。创伤通常与其他病变相关,并与非常严重的创伤或减速有关。由于关于这一主题的出版物的缺乏和发病率的降低,我们在此报告了1986年至1991年期间在圣保罗大学医学院总医院急救中心就诊的5例钝性腹部创伤伴胆囊病变的患者。此外,我们分析了这种创伤的发生率、相关病变的存在、治疗、患者的发病率和死亡率,并对文献进行了回顾。
{"title":"Gallbladder injuries due to blunt abdominal trauma: report on five cases and review of the literature.","authors":"L F Zantut,&nbsp;M A Machado,&nbsp;A L de Souza,&nbsp;P Volpe,&nbsp;A J Rodrigues Júnior,&nbsp;R S Poggetti,&nbsp;D Birolini","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Gallbladder lesions by blunt abdominal trauma are rare, due to the organ's anatomical particularities. Diagnosis is difficult, and it generally occurs during surgery. The trauma is usually associated with other lesions and is related to very serious traumas or to deceleration. Due to the scarcity of publications on this topic and to its reduced incidence, we present here a report of five patients who had suffered blunt abdominal trauma with gallbladder lesion and who were attended at the General Hospital (of the University of São Paulo Medical School) Emergency Service between 1986 and 1991. Furthermore, we analyze the incidence of this trauma, presence of associated lesion, treatment, morbidity and mortality of the patients, as well as a review of the literature.</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 6","pages":"285-8"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12515098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the physical fitness by the Bruno Balke protocol in sedentary and wheelchair trained paraplegic patients. 用Bruno Balke方案评价久坐和轮椅训练截瘫患者的身体健康。
Pub Date : 1992-11-01
J M Greve, A Santomauro, J Chiovatto, M I Sampaio, L R Battistella, T E de Barros Filho

The Bruno Balke test is one of the methods available to measure the oxygen intake in wheelchair users. The equation of the test is:intake O2 = 33+ (speed average-133) x 0.17 ml/kg x min. (-1). The average speed represents the acceleration and may be used to measure the level of physical fitness. In order to verify the efficiency of this kind of evaluation, we selected ten male, sedentary paraplegic patients, level D5-D12 in an ordinary rehabilitation program and ten paraplegic athletes. All of them were submitted to the Bruno Balke test. The results demonstrated that the average speed, the covered distance and the oxygen intake were significantly greater in athletes than in sedentary individuals.

布鲁诺·巴尔克测试是一种测量轮椅使用者氧气摄入量的方法。试验公式为:进气O2 = 33+(平均速度-133)× 0.17 ml/kg × min.(-1)。平均速度代表加速度,可以用来衡量身体健康水平。为了验证这种评估的有效性,我们选择了10名男性久坐截瘫患者,普通康复计划中D5-D12级和10名截瘫运动员。他们都接受了布鲁诺·巴尔克测试。结果表明,运动员的平均速度、覆盖距离和氧气摄入量明显大于久坐不动的人。
{"title":"Evaluation of the physical fitness by the Bruno Balke protocol in sedentary and wheelchair trained paraplegic patients.","authors":"J M Greve,&nbsp;A Santomauro,&nbsp;J Chiovatto,&nbsp;M I Sampaio,&nbsp;L R Battistella,&nbsp;T E de Barros Filho","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Bruno Balke test is one of the methods available to measure the oxygen intake in wheelchair users. The equation of the test is:intake O2 = 33+ (speed average-133) x 0.17 ml/kg x min. (-1). The average speed represents the acceleration and may be used to measure the level of physical fitness. In order to verify the efficiency of this kind of evaluation, we selected ten male, sedentary paraplegic patients, level D5-D12 in an ordinary rehabilitation program and ten paraplegic athletes. All of them were submitted to the Bruno Balke test. The results demonstrated that the average speed, the covered distance and the oxygen intake were significantly greater in athletes than in sedentary individuals.</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 6","pages":"242-4"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12514570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The vertebral artery: its relationship with adjoining tissues in its course intra and inter transverse processes in man. 椎动脉:在人体横突内和横突间与邻近组织的关系。
Pub Date : 1992-11-01
R P Chopard, M H de Miranda Neto, G A Lucas, M R Chopard

The authors study the vertebral artery from its origin to termination, especially in its course inter and intra transverse process and show its relation to venous and nervous structures, as well as its behavior toward adjacent conjunctive tissue. They discuss the relation of the anatomy to the physiopathology of the vertebral artery and come to the conclusion that the vertebral artery is fixed to adjacent structures in the fibrous osteomuscular tunnel by means of a continuous lamina of collagen along its entire course and that there is considerable independence between the artery and the branches of these final nerves.

作者研究了椎动脉从起源到终止,特别是在它的过程中,横向突间和横向突内,并说明了它与静脉和神经结构的关系,以及它对邻近结缔组织的行为。他们讨论了解剖与椎动脉生理病理的关系,并得出结论,椎动脉通过沿其整个过程的连续胶原层固定在纤维骨骼肌隧道中的邻近结构上,并且在动脉和这些最终神经的分支之间存在相当大的独立性。
{"title":"The vertebral artery: its relationship with adjoining tissues in its course intra and inter transverse processes in man.","authors":"R P Chopard,&nbsp;M H de Miranda Neto,&nbsp;G A Lucas,&nbsp;M R Chopard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors study the vertebral artery from its origin to termination, especially in its course inter and intra transverse process and show its relation to venous and nervous structures, as well as its behavior toward adjacent conjunctive tissue. They discuss the relation of the anatomy to the physiopathology of the vertebral artery and come to the conclusion that the vertebral artery is fixed to adjacent structures in the fibrous osteomuscular tunnel by means of a continuous lamina of collagen along its entire course and that there is considerable independence between the artery and the branches of these final nerves.</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 6","pages":"245-50"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12514569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decalcification of mineralized rat mandible tissues with the aid of microwaves. 微波对矿化大鼠下颌骨组织脱钙的影响。
Pub Date : 1992-11-01
M R Faria, P Dechichi, S de M Rode
{"title":"Decalcification of mineralized rat mandible tissues with the aid of microwaves.","authors":"M R Faria,&nbsp;P Dechichi,&nbsp;S de M Rode","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 6","pages":"283-4"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12513750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of X-chromatin in pregnant women during the second trimester of gestation. 妊娠中期妇女x -染色质的频率。
Pub Date : 1992-09-01
L C De Sampaio, L F De Sampaio Neto, J Boschini Filho, M Wajchenberg, J A Galvão, M Ferreiro, N F Novo

The frequency of X-chromatin was determined in pregnant women during the second trimester of gestation in order to establish possible correlations with the changes in steroid hormone levels occurring during this period and compare the curve with that for normal nonpregnant women. The mean frequency of X-chromatin in oral mucosa cells from a salivary suspension was 19.97% for the 24 patients studied, a statistically higher value than that obtained for nonpregnant women.

在妊娠中期测定了孕妇中x -染色质的频率,以确定在此期间发生的类固醇激素水平变化的可能相关性,并将曲线与正常未怀孕妇女的曲线进行比较。在研究的24例患者中,唾液悬浮液中口腔黏膜细胞中x -染色质的平均频率为19.97%,统计上高于未怀孕妇女。
{"title":"Frequency of X-chromatin in pregnant women during the second trimester of gestation.","authors":"L C De Sampaio,&nbsp;L F De Sampaio Neto,&nbsp;J Boschini Filho,&nbsp;M Wajchenberg,&nbsp;J A Galvão,&nbsp;M Ferreiro,&nbsp;N F Novo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The frequency of X-chromatin was determined in pregnant women during the second trimester of gestation in order to establish possible correlations with the changes in steroid hormone levels occurring during this period and compare the curve with that for normal nonpregnant women. The mean frequency of X-chromatin in oral mucosa cells from a salivary suspension was 19.97% for the 24 patients studied, a statistically higher value than that obtained for nonpregnant women.</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 5","pages":"195-9"},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12513939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arthroplasty of the knee--indications and contraindications. 膝关节置换术——适应症和禁忌症。
Pub Date : 1992-09-01
L A Mestriner

Total knee arthroplasty has been showed to be a satisfactory procedure mainly in relation to designs evolution of condylar or surface prostheses. In this matter, the concepts of prostheses of Gunston Polycentric (2), Freeman-Swanson (1) and the Total Condylar (3) were particularly important. The present status of development of condylar or surface arthroplasties allows to establish that in the majority of cases, arthrodesis of the knee is a salvage procedure. The alternative procedures indicated must always be considered. The conservative treatments as anti-inflammatory drugs and physiotherapy as well as arthroscopy, arthrotomy, synovectomy and osteotomies can be performed. These procedures are indicated depending on age, joint condition and type of disease. The knee arthroplasty requires skill and training of the surgeon, particularly if we consider the deformities and instabilities to be corrected and joint function to be aimed. On the other hand, the major problem may be the selection of the patient who will be operated on for a given type of total knee arthroplasty.

全膝关节置换术已被证明是一种令人满意的手术,主要涉及髁突或表面假体的设计和发展。在这个问题上,Gunston Polycentric(2)、Freeman-Swanson(1)和Total Condylar(3)假体的概念尤为重要。目前髁突或表面关节置换术的发展状况表明,在大多数情况下,膝关节置换术是一种救助性手术。必须始终考虑所指出的替代程序。保守治疗如消炎药、物理治疗及关节镜、关节切开术、滑膜切除术、截骨术。这些手术是根据年龄、关节状况和疾病类型而定的。膝关节置换术需要外科医生的技能和训练,特别是如果我们考虑到要纠正的畸形和不稳定以及关节功能的目标。另一方面,主要的问题可能是选择要进行特定类型全膝关节置换术的患者。
{"title":"Arthroplasty of the knee--indications and contraindications.","authors":"L A Mestriner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Total knee arthroplasty has been showed to be a satisfactory procedure mainly in relation to designs evolution of condylar or surface prostheses. In this matter, the concepts of prostheses of Gunston Polycentric (2), Freeman-Swanson (1) and the Total Condylar (3) were particularly important. The present status of development of condylar or surface arthroplasties allows to establish that in the majority of cases, arthrodesis of the knee is a salvage procedure. The alternative procedures indicated must always be considered. The conservative treatments as anti-inflammatory drugs and physiotherapy as well as arthroscopy, arthrotomy, synovectomy and osteotomies can be performed. These procedures are indicated depending on age, joint condition and type of disease. The knee arthroplasty requires skill and training of the surgeon, particularly if we consider the deformities and instabilities to be corrected and joint function to be aimed. On the other hand, the major problem may be the selection of the patient who will be operated on for a given type of total knee arthroplasty.</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 5","pages":"213-7"},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12514567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semiquantitative culture in diagnosing venous catheter-related sepsis. 半定量培养诊断静脉导管相关性脓毒症。
Pub Date : 1992-09-01
A Capone Neto, A von Nowakonski, A Basile Filho, S B Rizoli, M Mantovani, R G Terzi

Since Aubaniac (1) described the puncture of the subclavian vein in 1952, and specially after the standardization of parenteral nutrition by Dudrick et al. (11) in 1968, much has been published about complications caused by percutaneous central venous catheterization. Among the various complications provoked by this procedure, a very important one is "primary sepsis" or "catheter-related sepsis", both because of its frequency and because of the morbidity and mortality it causes (18,19). It is, however, difficult to diagnose this complication. The main difficulty lies in differentiating catheters that are really causing sepsis from those that, though showing "positive culture" do not cause bacteremia and are not responsible for the occasional signs of infection that a patient may show (6,7). This difficulty in diagnosing has led to the recommendation that all catheters suspected of causing sepsis be systematically removed. This procedure has the effect of exposing patients in serious condition and with limited venous access to the risks of new punctures. Usually these risks are unnecessary, since 75 to 90% of the catheters removed for this reason are not the real source of infection (3, 17, 19, 21, 22). In 1977, Maki et al. (18) proposed a semiquantitative catheter tip culture that showed considerable correlation with positive hemoculture for the same microorganisms; that is, capable of identifying which "positive catheters" were really causing sepsis. Subsequent research confirmed these results, showing that the semiquantitative catheter tip culture had specificity and sensibility over 80% (10, 15).(ABSTRACT TRUNCATED AT 250 WORDS)

自Aubaniac(1)于1952年描述锁骨下静脉穿刺以来,特别是在1968年Dudrick等人(11)将肠外营养标准化之后,关于经皮中心静脉置管引起的并发症的报道越来越多。在该手术引起的各种并发症中,一个非常重要的并发症是“原发性脓毒症”或“导管相关性脓毒症”,这既是因为它的频率,也是因为它引起的发病率和死亡率(18,19)。然而,这种并发症很难诊断。主要的困难在于区分真正引起败血症的导管与那些虽然显示“阳性培养”但不会引起菌血症的导管,也不会引起患者可能出现的偶然感染迹象(6,7)。这种诊断上的困难导致建议所有怀疑引起败血症的导管系统地切除。这种方法会使病情严重且静脉通路有限的患者暴露在新穿刺的风险中。通常这些风险是不必要的,因为75%至90%的导管因此被切除并不是真正的感染源(3,17,19,21,22)。1977年,Maki等人(18)提出了一种半定量的导管尖端培养方法,该方法对同一种微生物与阳性血液培养有相当大的相关性;也就是说,能够识别哪些“阳性导管”真正引起了败血症。随后的研究证实了这些结果,表明半定量导管尖端培养的特异性和敏感性超过80%(10,15)。(摘要删节250字)
{"title":"Semiquantitative culture in diagnosing venous catheter-related sepsis.","authors":"A Capone Neto,&nbsp;A von Nowakonski,&nbsp;A Basile Filho,&nbsp;S B Rizoli,&nbsp;M Mantovani,&nbsp;R G Terzi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since Aubaniac (1) described the puncture of the subclavian vein in 1952, and specially after the standardization of parenteral nutrition by Dudrick et al. (11) in 1968, much has been published about complications caused by percutaneous central venous catheterization. Among the various complications provoked by this procedure, a very important one is \"primary sepsis\" or \"catheter-related sepsis\", both because of its frequency and because of the morbidity and mortality it causes (18,19). It is, however, difficult to diagnose this complication. The main difficulty lies in differentiating catheters that are really causing sepsis from those that, though showing \"positive culture\" do not cause bacteremia and are not responsible for the occasional signs of infection that a patient may show (6,7). This difficulty in diagnosing has led to the recommendation that all catheters suspected of causing sepsis be systematically removed. This procedure has the effect of exposing patients in serious condition and with limited venous access to the risks of new punctures. Usually these risks are unnecessary, since 75 to 90% of the catheters removed for this reason are not the real source of infection (3, 17, 19, 21, 22). In 1977, Maki et al. (18) proposed a semiquantitative catheter tip culture that showed considerable correlation with positive hemoculture for the same microorganisms; that is, capable of identifying which \"positive catheters\" were really causing sepsis. Subsequent research confirmed these results, showing that the semiquantitative catheter tip culture had specificity and sensibility over 80% (10, 15).(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 5","pages":"222-6"},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12514568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytology by capillarity and anatomopathological diagnosis of solid breast tumors. 乳腺实体瘤的毛细细胞学及解剖病理诊断。
Pub Date : 1992-09-01
A A de Freitas Neto, S Kurbet, E Barreto, J E Nestarez

A study was conducted on material obtained by capillarity puncture (74 punctures) from 71 patients with breast tumors. The material was fixed in absolute alcohol and stained by the Papanicolaou method and the result was classified as insufficient material, or as negative, suspect or positive cytology. After tumor exeresis, the anatomopathological results of each patient were compared to the cytology data. A single false-positive case was obtained among 44 patients (97% specificity) and 9 false-negative cases were obtained among 16 patients (56% sensitivity).

对71例乳腺肿瘤患者进行了74次毛细穿刺所得材料的研究。将材料固定在无水酒精中,用Papanicolaou法染色,结果被分类为材料不足、阴性、可疑或阳性细胞学。肿瘤切除后,将每位患者的解剖病理结果与细胞学数据进行比较。44例患者中出现1例假阳性(特异性97%),16例患者中出现9例假阴性(敏感性56%)。
{"title":"Cytology by capillarity and anatomopathological diagnosis of solid breast tumors.","authors":"A A de Freitas Neto,&nbsp;S Kurbet,&nbsp;E Barreto,&nbsp;J E Nestarez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study was conducted on material obtained by capillarity puncture (74 punctures) from 71 patients with breast tumors. The material was fixed in absolute alcohol and stained by the Papanicolaou method and the result was classified as insufficient material, or as negative, suspect or positive cytology. After tumor exeresis, the anatomopathological results of each patient were compared to the cytology data. A single false-positive case was obtained among 44 patients (97% specificity) and 9 false-negative cases were obtained among 16 patients (56% sensitivity).</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 5","pages":"209-12"},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12513940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paracoccidioidomycosis in a patient with HIV-1 infection. 1例HIV-1感染患者的副球孢子菌病。
Pub Date : 1992-09-01
E Bagatin, V L Gonçalves, V P Sabongi, M N Sotto
{"title":"Paracoccidioidomycosis in a patient with HIV-1 infection.","authors":"E Bagatin,&nbsp;V L Gonçalves,&nbsp;V P Sabongi,&nbsp;M N Sotto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 5","pages":"193-4"},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12513938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histological study of the endometrium in menopausal women with breast carcinoma. 绝经期乳腺癌患者子宫内膜的组织学研究。
Pub Date : 1992-09-01
A C Nazário, G R de Lima, A C Alves, N F Novo

The first reference concerning the multiple primary malignant neoplasms was made by Bilroth, 1880 and since then a large number of studies have been published. Furthermore, an increasing incidence of simultaneous cancers are currently observed (16,18). At the same time, several retrospective populational studies evidenced the association between breast and endometrium carcinoma. It is well known that both uterus and breast are hormone-dependent organs and are likely to be influenced by the same oncogenic stimulus, either of endocrine nature or dietary origin (2, 3, 14). The risk of developing endometrial carcinoma is higher in patients already affected by breast neoplasm and is much more evident in older women within the first five years following the diagnosis of breast tumor. Conversely, patients with endometrial carcinoma may present a second mammary neoplasm and the relative risk is around 2.0 (1, 17). Although the existence of a correlation between these two primary malignant neoplasms is clearly observed, the absence of systematic studies directed to the screening of endometrial cancer in women with breast carcinoma is surprising. This study deals with histological analysis of the endometrium of postmenopausal patients with breast cancer and aims to determine the possible changes that might have occurred in the onset of the disease.

关于多发原发恶性肿瘤的文献最早是由Bilroth于1880年提出的,此后发表了大量的研究。此外,目前观察到同时发生癌症的发生率不断增加(16,18)。同时,一些回顾性人群研究证实了乳腺癌和子宫内膜癌之间的联系。众所周知,子宫和乳房都是激素依赖性器官,可能受到内分泌或饮食来源的相同致癌刺激的影响(2,3,14)。已经患过乳腺肿瘤的患者发生子宫内膜癌的风险更高,在诊断出乳腺肿瘤后的头五年内,这一风险在老年妇女中更为明显。相反,子宫内膜癌患者可能出现第二乳腺肿瘤,其相对风险约为2.0(1,17)。虽然这两种原发性恶性肿瘤之间存在相关性,但令人惊讶的是,缺乏针对乳腺癌妇女子宫内膜癌筛查的系统研究。本研究对绝经后乳腺癌患者的子宫内膜进行组织学分析,目的是确定在疾病发病时可能发生的变化。
{"title":"Histological study of the endometrium in menopausal women with breast carcinoma.","authors":"A C Nazário,&nbsp;G R de Lima,&nbsp;A C Alves,&nbsp;N F Novo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The first reference concerning the multiple primary malignant neoplasms was made by Bilroth, 1880 and since then a large number of studies have been published. Furthermore, an increasing incidence of simultaneous cancers are currently observed (16,18). At the same time, several retrospective populational studies evidenced the association between breast and endometrium carcinoma. It is well known that both uterus and breast are hormone-dependent organs and are likely to be influenced by the same oncogenic stimulus, either of endocrine nature or dietary origin (2, 3, 14). The risk of developing endometrial carcinoma is higher in patients already affected by breast neoplasm and is much more evident in older women within the first five years following the diagnosis of breast tumor. Conversely, patients with endometrial carcinoma may present a second mammary neoplasm and the relative risk is around 2.0 (1, 17). Although the existence of a correlation between these two primary malignant neoplasms is clearly observed, the absence of systematic studies directed to the screening of endometrial cancer in women with breast carcinoma is surprising. This study deals with histological analysis of the endometrium of postmenopausal patients with breast cancer and aims to determine the possible changes that might have occurred in the onset of the disease.</p>","PeriodicalId":74720,"journal":{"name":"Revista paulista de medicina","volume":"110 5","pages":"218-21"},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12513941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Revista paulista de medicina
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1