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Clinical question: Can virtual reality be an effective adjunctive to conventional treatment in patients with chronic lower back pain? 临床问题:虚拟现实能否有效辅助慢性下背痛患者的常规治疗?
Jee Hun Jang, Jan Miller

Background: Chronic low back pain is the most prevalent chronic pain condition worldwide, accounting for 15-20% of physician visits and costing billions of dollars. Without adequate treatment, it can lead to substance use disorder and increased risk of suicide. Current treatments include non-steroidal anti-inflammatory drugs (NSAIDs), opioids, surgery, and non-pharmacological adjuncts. Evidence suggests cognitive behavioral therapy (CBT) as adjunctive therapy can improve patient commitment to treatment but not pain intensity. However, CBT is limited due to availability, location and shortage of trained personnel. Virtual reality (VR) has been growing in interest in providing affordable, digital, home-based, and self-directed CBT to address the psychosocial aspect of pain.

Methods: We searched the literature for meta-analysis, randomized control trials (RCT), and systemic reviews using the PubMed database with the terms virtual reality and chronic low back pain.

Results: The review identified 31 studies. Six were chosen that were applicable to our clinical questions, one systematic review, two meta-analysis and three RCTs. The RCTs showed that virtual reality can improve pain in patients with chronic lower back pain as an effective adjunctive to pharmacological and surgical intervention. The systemic review and meta-analysis also concluded that VR is beneficial in pain management however, due to inconsistent results and the multifactorial aspect of chronic pain.

Conclusions: Thus further research is required. The number of randomized trials, evidence on long-term application, and the efficacy of self-directed versus guided VR treatment limit our understanding of this topic.

背景:慢性腰背痛是全球最常见的慢性疼痛,占就诊人数的 15-20%,花费数十亿美元。如果得不到适当的治疗,会导致药物使用障碍,增加自杀风险。目前的治疗方法包括非甾体抗炎药(NSAIDs)、阿片类药物、手术和非药物辅助治疗。有证据表明,认知行为疗法(CBT)作为辅助疗法可以改善患者对治疗的承诺,但不能改善疼痛强度。然而,由于可用性、地点和训练有素人员的短缺,认知行为疗法受到了限制。虚拟现实(VR)在提供经济实惠、数字化、基于家庭和自我指导的 CBT 以解决疼痛的社会心理问题方面越来越受到关注:我们使用 PubMed 数据库,以虚拟现实和慢性腰背痛为关键词,检索了荟萃分析、随机对照试验 (RCT) 和系统综述等文献:结果:综述确定了 31 项研究。结果:综述发现了 31 项研究,其中 6 项与我们的临床问题相关,1 项为系统综述,2 项为荟萃分析,3 项为随机对照试验。研究性试验表明,虚拟现实技术可以有效辅助药物和手术治疗,改善慢性腰背痛患者的疼痛状况。系统综述和荟萃分析也得出结论认为,虚拟现实技术有益于疼痛治疗,但由于结果不一致以及慢性疼痛的多因素性:因此,还需要进一步的研究。随机试验的数量、长期应用的证据以及自主 VR 治疗与引导 VR 治疗的疗效都限制了我们对这一主题的理解。
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引用次数: 0
Hospital Admission Rates and Mortality Among Emergency Department Patients with COVID-19 Discharged with Remote Patient Monitoring with or without HO2ME - A Value-Based Approach. 急诊科 COVID-19 患者出院时使用或不使用 HO2ME 进行远程患者监护的入院率和死亡率 - 一种基于价值的方法。
Stacia Shipman, Tomas Owens, Chelsey Gilbertson, Jeffrey Shipman

Background: The pandemic caused by the novel Coronavirus 2019 (COVID-19) overwhelmed healthcare systems with emergency department (ED) and hospital overcrowding. Our hospital system was able to discharge a subset of COVID-19 patients home with remote patient monitoring (RPM) and home oxygen (HO2ME) if needed, which opened up beds for the more critical patients. The objective of this study was to review the all-cause 30-day mortality and admission rates for patients chosen for our program, and to additionally examine the financial impact.

Methods: This was a retrospective cohort study of ED patients who were included if they tested positive for SARS-CoV-2 RNA on nasopharyngeal swab and received emergency care for COVID-19 at any INTEGRIS facility during 10/27/2020-9/8/2021. For the primary statistical analysis, descriptive statistics were calculated and reported as medians with interquartile ranges. For the purpose of financial analysis, we filtered a subset of insured patients who were sent home with oxygen.

Results: 490 patients were enrolled with a median age of 62 and median body mass index (BMI) of 31. Of the 490 patients, 151 patients (31%) met requirements for home oxygen and were discharged with oxygen. Over a median enrollment time of 15 days, patients discharged from the emergency department on the RPM program were observed to have an all-cause 30-day mortality rate of 3.2% (95% Cl, 1.8%-5.2%). The observed rate of all-cause hospital admission within 30 days was 17%. The financial analysis revealed savings to insurance companies.

Conclusions: This study demonstrated that rapidly deploying a RPM program for patients with acute COVID-19 infection allowed our health system to safely care for patients in their homes. The program opened hospital beds for more severe and critically ill COVID-19 patients who necessitated more intense monitoring and inpatient care, while simultaneously observing low 30-day all-cause mortality and hospital admission rates.

背景:新型冠状病毒 2019(COVID-19)引起的大流行使医疗系统不堪重负,急诊科(ED)和医院人满为患。我们的医院系统能够让一部分 COVID-19 患者出院回家,并在需要时提供远程患者监护(RPM)和家庭供氧(HO2ME),这就为更危重的患者腾出了床位。本研究的目的是回顾被选中参加我们计划的患者的 30 天全因死亡率和入院率,并进一步研究其对经济的影响:这是一项回顾性队列研究,研究对象是在 2020 年 10 月 27 日至 2021 年 8 月 9 日期间,鼻咽拭子 SARS-CoV-2 RNA 检测呈阳性并在任何一家 INTEGRIS 机构接受 COVID-19 急诊治疗的急诊患者。在主要统计分析中,我们计算了描述性统计数据,并以中位数和四分位数间距的形式进行报告。为了进行财务分析,我们筛选了带氧回家的投保患者子集:490 名患者的中位年龄为 62 岁,中位体重指数 (BMI) 为 31。在 490 名患者中,有 151 名患者(31%)符合家庭供氧的要求,并带氧出院。在 15 天的中位注册时间内,观察到从急诊科出院的 RPM 计划患者的 30 天全因死亡率为 3.2%(95% Cl,1.8%-5.2%)。观察到的 30 天内全因入院率为 17%。财务分析显示,保险公司节省了费用:这项研究表明,为急性 COVID-19 感染患者快速部署 RPM 计划使我们的医疗系统能够安全地在家中护理患者。该计划为病情更严重、需要更严密监测和住院治疗的 COVID-19 患者开放了病床,同时观察到 30 天全因死亡率和入院率都很低。
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引用次数: 0
Investigation of Geographical Disparities: The Use of An Interpolation Method For Cancer Registry Data. 地理差异调查:癌症登记数据的插值方法的使用。
Janis E Campbell, Ami Elizabeth Sedani, Hanh Dung N Dao, Ayesha Sambo, Mark Doescher, Amanda Janitz

The American Cancer Society estimated 1.9 million diagnosed cancer cases and 608,570 cancer deaths in 2021 in the US; for Oklahoma, they estimated 22,820 cases and 8,610 deaths. This project aimed to demonstrate a method to systematically describe cancer in an accurate and visually attractive, yet simple to make, interpolated map using ZIP Code level registry data, as it is the smallest area unit with high accuracy using inverse distance weighting. We describe a process of creating smoothed maps with an appropriate, well-described, simple, replicable method. These smoothed maps display low (cold) or high (hot) areas of incidence rates of: (a) all cancer combined, (b) colorectal cancer and lung cancer rates by gender, (c) female breast cancer, and (d) prostate cancer, by ZIP Codes for Oklahoma from 2013-2017. The methods we present in this paper provide an effective visualization to pinpoint low (cold) or high (hot) areas of cancer incidence.

美国癌症协会估计,2021年美国有190万癌症确诊病例和608570例癌症死亡病例;在俄克拉荷马州,他们估计有22820例病例和8610例死亡。该项目旨在演示一种方法,通过使用邮政编码级别的注册表数据,以精确且具有视觉吸引力但制作简单的插值地图系统地描述癌症,因为它是最小的面积单位,使用逆距离加权具有高精度。我们描述了一个使用适当、描述良好、简单、可复制的方法创建平滑贴图的过程。这些平滑地图显示了2013-2017年俄克拉荷马州所有癌症合并发病率的低(冷)或高(热)区域,(b)按性别划分的癌症和癌症结直肠癌发病率,(c)女性癌症乳腺癌和(d)按邮政编码划分的癌症前列腺癌。我们在本文中提出的方法提供了一个有效的可视化来精确定位癌症发病率的低(冷)或高(热)区域。
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引用次数: 0
In patients with osteoarthritis, is curcumin, compared to placebo, effective in reducing pain? 对于骨关节炎患者,与安慰剂相比,姜黄素是否能有效减轻疼痛?
Morgan Van Ameyde, Jeffrey Hodgden

Clinical question: In patients with osteoarthritis, is curcumin, compared to placebo, effective in reducing pain?

Answer: Yes. Studies have shown that curcumin extract has benefit in treating osteoarthritic pain, compared to placebo. It is reasonable to use curcumin in addition to traditional osteoarthritis treatments, as studies show it has a low side effect profile. However, a greater number of studies as well as larger studies are needed to definitively recommend curcumin, especially as a replacement for more traditional therapies.

Level of evidence of the answer: B.

临床问题:与安慰剂相比,对于骨关节炎患者,姜黄素是否能有效减轻疼痛?答:是的。研究表明,与安慰剂相比,姜黄素提取物对治疗骨关节炎疼痛有好处。除了传统的骨关节炎治疗方法外,使用姜黄素是合理的,因为研究表明它的副作用很小。然而,需要更多的研究和更大规模的研究来明确推荐姜黄素,特别是作为更传统疗法的替代品。答案的证据程度:B。
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引用次数: 0
A Snapshot of Oklahoma's CHR/CHW Workforce: Results from the Region 6 Training Needs Assessment Survey, 2019. 俄克拉荷马州 CHR/CHW 劳动力概况:第 6 地区培训需求评估调查结果,2019 年。
Kerstin M Reinschmidt, Olawale Dudubo, Charles F Shorter, R D Dickens, Marisa New, Pam Rask, Thomas A Teasdale

Background –: The Region 6 South Central Public Health Training Center conducts needs assessments to inform the development of online trainings tailored to the HRSA Region 6 health and public health workforce. The purpose of this study was to assess Oklahoma's Community Health Representative (CHR) / Community Health Worker (CHW) workforce characteristics, current trainings, and training needs to guide the development of online trainings.

Methods –: This survey-based needs assessment for health and public health workforce training needs asked about alternative job titles, top three health issues addressed, roles played, skills used, current trainings, and training needs. Descriptive statistical analysis provided insights about CHRs/CHWs. The Fisher's exact test was used to compare frequency of responses between CHRs and CHWs, with p-values <0.05 considered significant. We analyzed qualitative data by using a modified content analysis.

Results –: Fifty-one self-identified CHRs/CHWs in Oklahoma participated in the 2019 regional health and public health training needs assessment. Most CHRs/CHWs were female and identified as "frontline public health workers." Respondents reported a range of educational attainment and diverse job titles. CHRs worked at tribal health or public health organizations primarily in rural areas. Most CHWs worked in urban areas and were employed by state and local health departments or community-based organizations. CHRs/CHWs had a broad spectrum of roles and skills, with required trainings reflecting various organizational needs. CHRs/CHWs expressed strong interest in receiving additional trainings via multiple delivery formats.

Discussion and conclusions –: Oklahoma's CHRs/CHWs would benefit from and utilize workforce development, including trainings on a broad spectrum of roles and skills in multiple delivery formats. Potential employers and funders across the state would benefit from education on CHRs/CHWs as a workforce, team-integration, and sustainable funding.

背景--:第 6 地区中南部公共卫生培训中心开展需求评估,为开发针对第 6 地区卫生和公共卫生工作人员的在线培训提供信息。本研究的目的是评估俄克拉荷马州社区卫生代表 (CHR) / 社区卫生工作者 (CHW) 劳动力的特点、当前的培训和培训需求,以指导在线培训的开发:这项以调查为基础的卫生和公共卫生劳动力培训需求评估询问了替代职称、处理的前三个卫生问题、扮演的角色、使用的技能、当前的培训和培训需求。描述性统计分析提供了有关 CHRs/CHWs 的见解。费雪精确检验用于比较卫生保健人员和保健社工的回答频率,P 值为 结果--:俄克拉荷马州有 51 名自我认定的卫生保健人员/保健工作者参与了 2019 年地区卫生和公共卫生培训需求评估。大多数 CHRs/CHWs 都是女性,并被认定为 "一线公共卫生工作者"。受访者报告了不同的教育程度和不同的职称。社区保健员主要在农村地区的部落卫生或公共卫生组织工作。大多数社区保健员在城市地区工作,受雇于州和地方卫生部门或社区组织。CHRs/CHWs 的角色和技能范围很广,所需的培训反映了不同组织的需求。社区保健医生/保健工作者对通过多种形式接受更多培训表达了强烈的兴趣:俄克拉荷马州的儿童保健医生/保健工作者将受益于并利用劳动力发展,包括以多种形式提供的有关各种角色和技能的培训。全州的潜在雇主和资助者将受益于有关作为劳动力的 CHRs/CHWs 的教育、团队整合和可持续资助。
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引用次数: 0
Investigation of Geographical Disparities: The Use of An Interpolation Method For Cancer Registry Data. 地理差异调查:癌症登记数据的插值方法的使用。
Pub Date : 2021-06-24 DOI: 10.21203/rs.3.rs-592167/v1
Janis E Campbell, Ami E. Sedani, H. Dao, Ayesha B Sambo, M. Doescher, Amanda E. Janitz
The American Cancer Society estimated 1.9 million diagnosed cancer cases and 608,570 cancer deaths in 2021 in the US; for Oklahoma, they estimated 22,820 cases and 8,610 deaths. This project aimed to demonstrate a method to systematically describe cancer in an accurate and visually attractive, yet simple to make, interpolated map using ZIP Code level registry data, as it is the smallest area unit with high accuracy using inverse distance weighting. We describe a process of creating smoothed maps with an appropriate, well-described, simple, replicable method. These smoothed maps display low (cold) or high (hot) areas of incidence rates of: (a) all cancer combined, (b) colorectal cancer and lung cancer rates by gender, (c) female breast cancer, and (d) prostate cancer, by ZIP Codes for Oklahoma from 2013-2017. The methods we present in this paper provide an effective visualization to pinpoint low (cold) or high (hot) areas of cancer incidence.
美国癌症协会估计,2021年美国将有190万确诊癌症病例和608570例癌症死亡;在俄克拉荷马州,他们估计有22820例病例和8610例死亡。该项目旨在展示一种方法,利用邮政编码级别的注册表数据,系统地准确、美观、简单地描述癌症,因为它是使用逆距离加权的高精度的最小面积单位。我们描述了用适当的、描述良好的、简单的、可复制的方法创建平滑地图的过程。这些平滑的地图显示了2013-2017年俄克拉荷马州低(冷)或高(热)发病率地区:(a)所有癌症的总和,(b)按性别划分的结直肠癌和肺癌发病率,(c)女性乳腺癌和(d)前列腺癌的发病率,按邮政编码划分。我们在本文中提出的方法提供了一个有效的可视化,以查明低(冷)或高(热)地区的癌症发病率。
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引用次数: 0
Are sterile glove precautions necessary for joint injections or is a general aseptic process sufficient? A Clin-IQ. 关节注射是否需要无菌手套防护措施,还是一般的无菌过程就足够了?Clin-IQ。
Gretchen McGee, Brooke Frantz, Anton Dreier, Philip Palmer

Background: Multiple studies have been conducted investigating the use of sterile vs non-sterile gloves. The aim of this Clin-IQ is to determine whether there is a clinically significant difference in the rate of infections in relation to the use of sterile vs non-sterile gloves for joint injections.

Conclusions: Multiple studies have shown no appreciable difference in outcomes using sterile vs clean gloves for a variety of clinical applications including joint injections.

背景:对无菌手套和非无菌手套的使用进行了多项研究。本临床- iq的目的是确定在使用无菌手套和非无菌手套进行关节注射时,感染率是否存在临床显著差异。结论:多项研究表明,在包括关节注射在内的各种临床应用中,使用无菌手套和清洁手套的结果没有明显差异。
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引用次数: 0
Diabetes among Hispanics in Oklahoma: Assessing Disparities to Guide Basic and Applied Research. 俄克拉何马州西班牙裔糖尿病患者:评估差异以指导基础和应用研究。
Kerstin M Reinschmidt, Alicia L Salvatore, Li Ji, Karla J Finnell, Angel E Giron Lopez, Eric R Bump, Timothy J Philip, Julie A Stoner

Background –: Diabetes, a leading cause of morbidity and mortality in the United States, disproportionally affects minority populations. In 2015, Hispanics, the largest minority in the country, had the third highest rate of diabetes prevalence and the third highest age-adjusted rate of diabetes-related mortality. Substantial progress in understanding diabetes disparities nationally and in many areas of the country has been made. However, little is known about diabetes and related mortality among Hispanics in Oklahoma, which is known as a Hispanic "new Settlement" state due to the relatively recent and substantial growth of this population.

Methods –: We used Oklahoma Behavioral and Risk Factor Surveillance Survey data (2011-2016) to calculate population estimates of diabetes prevalence and selected sociodemographic characteristics for Hispanic and Non-Hispanic adults in the state. We used Oklahoma Death Registry data to estimate diabetes-related mortality rates for Hispanic and Non-Hispanic adults for the same five-year period. We examined differences in diabetes prevalence and diabetes-related mortality across selected sociodemographic characteristics.

Results –: Hispanics are the largest minority group in Oklahoma. Spanish is the most common non-English language spoken in the state. Hispanics are younger, poorer, less educated and experience less access to health care compared to other populations in Oklahoma. While Hispanics had the fifth highest reported diabetes prevalence rate during the five-year period examined, they had the third highest diabetes-related mortality rate in the state.

Discussion and conclusions –: There is a need for community engagement and basic and applied research to help identify and reduce diabetes disparities in the growing Hispanic population in Oklahoma.

背景:糖尿病是美国发病率和死亡率的主要原因,对少数民族人群的影响不成比例。2015年,西班牙裔是美国最大的少数族裔,其糖尿病患病率和年龄调整后的糖尿病相关死亡率排名第三。在了解全国和国内许多地区的糖尿病差异方面取得了实质性进展。然而,人们对俄克拉何马州拉美裔人的糖尿病和相关死亡率知之甚少,由于该人口的相对近期和实质性增长,俄克拉何马州被称为拉美裔“新定居”州。方法:我们使用俄克拉荷马州行为和风险因素监测调查数据(2011-2016年)来计算该州西班牙裔和非西班牙裔成年人的糖尿病患病率和选定的社会人口统计学特征。我们使用俄克拉何马州死亡登记处的数据来估计相同五年期间西班牙裔和非西班牙裔成年人与糖尿病相关的死亡率。我们在选定的社会人口学特征中检查了糖尿病患病率和糖尿病相关死亡率的差异。结果:西班牙裔是俄克拉荷马州最大的少数民族。西班牙语是该州最常用的非英语语言。与俄克拉荷马州的其他人口相比,拉美裔人更年轻、更贫穷、受教育程度更低,获得医疗保健的机会也更少。在调查的五年期间,西班牙裔的糖尿病患病率排名第五,他们的糖尿病相关死亡率排名第三。讨论和结论:需要社区参与和基础和应用研究来帮助识别和减少俄克拉何马州不断增长的西班牙裔人口中的糖尿病差异。
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引用次数: 0
Spherocytosis 球形红细胞症
Pub Date : 2020-02-08 DOI: 10.32388/ggjnjo
A hereditary or acquired blood disorder characterized by the presence of smaller than normal, sphere-shaped erythrocytes. It results in hemolytic anemia and splenomegaly.
血友病一种遗传性或获得性血液疾病,其特征是红细胞小于正常的球形红细胞它会导致溶血性贫血和脾肿大。
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引用次数: 1
Contact dermatitis. 接触性皮炎。
Pub Date : 2020-02-07 DOI: 10.32388/ycop2a
W. A. Showman
The journal aims at promoting and maintaining communication among dermatologists, industrial physicians, allergists and clinical immunologists, as well as chemists and research workers involved in industry and the production of consumer goods. Papers are invited on clinical observations, diagnosis and methods of investigation of patients, therapeutic measures, organisation and legislation relating to the control of occupational and consumers' contact dermatitis, preventive measures and educational advice.
该杂志旨在促进和保持皮肤科医生、工业医生、过敏症专家和临床免疫学家,以及涉及工业和消费品生产的化学家和研究工作者之间的交流。欢迎就有关控制职业性和消费者接触性皮炎的临床观察、诊断和调查方法、治疗措施、组织和立法、预防措施和教育建议等方面发表论文。
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引用次数: 0
期刊
The Journal of the Oklahoma State Medical Association
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